Dapanorm-M 5mg/500mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or rapid breathing
- Severe nausea, vomiting, or abdominal pain
- Muscle pain or unusual tiredness
- Fruity breath odor
- Swelling of face, lips, or throat
- Decreased urine output or swelling in legs
- Severe pain, redness, or swelling in genital or perineal area with fever
- Blood in urine or stool
If experiencing severe symptoms, call emergency services immediately.
What is dapasach m 5mg/500mg tablet used for?
This medicine is a combination of dapagliflozin and metformin used to treat type 2 diabetes. It helps lower blood sugar by increasing glucose excretion in urine and reducing glucose production in the liver. Take it with meals as prescribed by your doctor.
- Generic Name: Dapagliflozin + Metformin
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dapasach m 5mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। इसमें डापाग्लिफ्लोज़िन और मेटफॉर्मिन दो सक्रिय तत्व होते हैं जो मिलकर ब्लड शुगर को कंट्रोल करने में मदद करते हैं। डापाग्लिफ्लोज़िन किडनी के जरिए अतिरिक्त शुगर को यूरिन से बाहर निकालता है, जबकि मेटफॉर्मिन लिवर में शुगर बनने की प्रक्रिया को कम करता है और शरीर की इंसुलिन के प्रति संवेदनशीलता बढ़ाता है। यह दवा उन वयस्कों के लिए है जिनका ब्लड शुगर सिर्फ डाइट और एक्सरसाइज से कंट्रोल नहीं हो पाता। इसे डॉक्टर की सलाह के अनुसार खाने के साथ लेना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जननांगों में फंगल इन्फेक्शन, यूरिनरी ट्रैक्ट इन्फेक्शन, जी मिचलाना, दस्त, पेट में असहजता, सिरदर्द और बार-बार पेशाब आना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें डायबिटिक कीटोएसिडोसिस, लैक्टिक एसिडोसिस, गंभीर यूरिनरी इन्फेक्शन और किडनी की समस्या शामिल हो सकती है। अगर आपको सांस लेने में तकलीफ, गंभीर पेट दर्द, मांसपेशियों में दर्द, असामान्य थकान या चेहरे-होंठ-गले में सूजन हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार खाने के साथ लें। टैबलेट को चबाएं या तोड़ें नहीं। दिनभर पर्याप्त पानी पिएं ताकि किडनी अतिरिक्त शुगर को बाहर निकाल सके और यूरिन इन्फेक्शन का खतरा कम हो। जननांगों और यूरिनरी हाइजीन का ध्यान रखें। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस और लो ब्लड शुगर का खतरा बढ़ सकता है। ब्लड शुगर की नियमित जांच करें। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के दवा बंद न करें।
💊 dapasach m 5mg/500mg tablet Uses & Benefits
[{"condition":"Type 2 Diabetes Mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes, especially when metformin alone is insufficient.","evidence":"Well-established"},{"condition":"Type 2 Diabetes with Cardiovascular Risk","description":"Dapagliflozin component may reduce the risk of cardiovascular death and hospitalization for heart failure in patients with type 2 diabetes and established cardiovascular disease.","evidence":"Well-established"},{"condition":"Type 2 Diabetes with Chronic Kidney Disease","description":"May slow the progression of kidney disease in patients with type 2 diabetes and diabetic nephropathy.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Weight Management in Type 2 Diabetes","description":"Dapagliflozin component may promote modest weight loss through urinary glucose excretion, but this is not a primary indication.","evidence":"Limited"},{"condition":"Non-Alcoholic Fatty Liver Disease (NAFLD)","description":"Some studies suggest potential benefit in improving liver enzymes and steatosis in patients with type 2 diabetes and NAFLD.","evidence":"Limited"}]
Primary treatment for: Type 2 Diabetes Mellitus
Also treats: Cardiovascular disease, Chronic kidney disease, Heart failure
📋 Drug Information
| Generic Name(s) | Dapagliflozin + Metformin |
| Brand Name | Cididap M 10mg/500mg Tablet |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | SGLT2 Inhibitor + Biguanide |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place. Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Dapagliflozin selectively inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules, reducing renal glucose reabsorption and increasing urinary glucose excretion, which lowers blood glucose independently of insulin. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and improves peripheral insulin sensitivity by activating AMP-activated protein kinase (AMPK). Together, they improve glycemic control through multiple pathways.
Mechanism Steps
💡 How to Take dapasach m 5mg/500mg tablet
Strength: Dapagliflozin 5 mg + Metformin 500 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily with meals, as prescribed by your doctor. The dose may be adjusted based on your blood sugar levels, kidney function, and overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially regarding kidney function. Dose should be adjusted based on renal function. Regular monitoring of renal function is recommended. |
| Renal Impairment | Dapagliflozin: No dose adjustment is required for mild to moderate renal impairment. Not recommended for severe renal impairment (eGFR <30 mL/min/1.73 m²). Metformin: Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73 m²). Dose adjustment may be needed for moderate renal impairment. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Dapagliflozin: No dose adjustment is required for mild to moderate hepatic impairment. Not recommended for severe hepatic impairment. Metformin: Use with caution in patients with hepatic impairment due to increased risk of lactic acidosis. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is dapagliflozin 10 mg and metformin 2000 mg. However, the exact dose depends on the individual patient's condition and should be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dapasach m 5mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | |
| Sulfonylureas | Major | |
| Alcohol | Major | |
| Iodinated contrast media | Major | |
| Diuretics | Moderate | |
| Cationic drugs | Moderate | |
| Nifedipine | Minor | |
| Furosemide | Minor |
🚨 Major Interactions
- Insulin or sulfonylureas
- Alcohol
- Iodinated contrast media
⚡ Moderate Interactions
- Diuretics
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, ranitidine, triamterene, trimethoprim, vancomycin)
🍷 Alcohol Interaction
Avoid excessive alcohol consumption while taking this medicine. Alcohol increases the risk of lactic acidosis, a rare but serious complication of metformin, and can also cause hypoglycemia. If you drink alcohol, do so in moderation and only after consulting your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Risk of lactic acidosis with metformin, especially in patients with renal impairment, liver disease, or excessive alcohol use.","Risk of diabetic ketoacidosis with dapagliflozin, which can occur even with normal blood glucose levels.","Increased risk of genital mycotic infections and urinary tract infections.","May cause volume depletion and hypotension; monitor hydration status.","Not recommended for patients with type 1 diabetes.","Discontinue before surgery or iodinated contrast procedures as advised by doctor.","May cause vitamin B12 deficiency with long-term use.","Use with caution in elderly patients due to increased risk of renal impairment."]
🤱 Lactation Safety
Not established from the available information. Dapagliflozin and metformin are excreted in human milk. Breastfeeding is not recommended while taking this medicine due to potential risk to the infant.
💊 Overdose Management
Overdose of this medicine may cause hypoglycemia (if combined with other antidiabetic agents), lactic acidosis, or severe gastrointestinal symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered to remove metformin in cases of severe lactic acidosis. Dapagliflozin is not significantly removed by hemodialysis.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once or twice daily with meals to reduce stomach upset. Do not crush, chew, or split the tablet unless your doctor advises otherwise. Stay well hydrated throughout the day to help your kidneys flush out excess glucose and reduce the risk of urinary infections. Maintain good genital and urinary hygiene to prevent infections. Avoid excessive alcohol consumption because it increases the risk of lactic acidosis and low blood sugar. Monitor your blood sugar levels regularly as advised. Inform your doctor if you have kidney or liver disease, are scheduled for surgery, or are pregnant or planning pregnancy. Do not stop this medicine suddenly without consulting your doctor. Keep this medicine out of reach of children and store it at room temperature away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, particularly renal impairment and dehydration. Regular monitoring of kidney function and blood sugar is recommended. Dose adjustments may be necessary based on renal function. Falls and fractures risk may be increased with dapagliflozin; take precautions.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative, such as insulin. Uncontrolled diabetes during pregnancy can harm both mother and baby. Preconception counseling is essential.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily stopped before surgery due to the risk of lactic acidosis and dehydration. Inform your surgeon and anesthesiologist that you are taking this medicine. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed for routine dental procedures, but if you are having surgery or are unable to eat normally, consult your doctor about dose adjustments.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is beneficial for managing diabetes, but take precautions to avoid hypoglycemia if you are also taking insulin or sulfonylureas. Check your blood sugar before and after exercise. Stay hydrated, especially if you are taking dapagliflozin, as it can cause mild dehydration. Avoid strenuous exercise in extreme heat.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine generally does not affect your ability to work or drive. However, if you experience dizziness or symptoms of low blood sugar (when combined with other antidiabetic agents), avoid driving or operating heavy machinery until you feel better. Take regular breaks if your job involves prolonged standing or physical activity, and stay hydrated.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as lactic acidosis, diabetic ketoacidosis, or severe allergic reactions, seek immediate medical attention and follow your doctor's advice regarding discontinuation. Your doctor may adjust or stop the medicine based on your kidney function, blood sugar control, or other health conditions.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to vitamin B12 deficiency due to metformin, which can cause anemia and nerve problems. Regular monitoring of vitamin B12 levels is advised. Dapagliflozin may continue to provide cardiovascular and renal benefits. Kidney function should be monitored periodically. Weight loss may be maintained. Rarely, long-term use may be associated with an increased risk of bone fractures or amputations, though evidence is limited.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are cornerstone therapies for type 2 diabetes and can complement or reduce the need for medication.
Evidence: Well-establishedAlternatives include sulfonylureas, DPP-4 inhibitors, GLP-1 receptor agonists, and insulin, depending on individual needs.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, patients with diabetes are at higher risk of infections, so ensure you are up to date with recommended vaccinations, including influenza and pneumococcal vaccines. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If crossing time zones, consult your doctor about adjusting the timing of your doses. Store at room temperature and protect from moisture. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few days, but it may take several weeks to see the full effect on HbA1c levels.
A: It is best taken with meals to reduce stomach upset and improve tolerability.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not stop taking this medicine without consulting your doctor. Diabetes is a chronic condition, and stopping medication can cause blood sugar to rise again.
🤔 Common Patient Concerns
🔄 Substitutes for dapasach m 5mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
dapatab m 5mg/500mg tabletOrris Pharmaceuticals ₹65.34 6.7% CHEAPER
-
dapixa m 5mg/500mg tablet erTas Med India Pvt Ltd ₹70.31 0.4% COSTLIER
-
justoza-m 5/500 tablet erMankind Pharma Ltd ₹72.18 3.1% COSTLIER
-
dexiglu m 5 tablet erFusion Healthcare Pvt Ltd ₹72.19 3.1% COSTLIER
-
gluxida m5 tablet erMetalis Lifesciences Pvt Ltd ₹73.59 5.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar levels but does not cure diabetes. Lifestyle changes and ongoing medical care are essential. - Myth: This medicine can be taken without food.
Fact: It is best taken with meals to reduce stomach upset and improve tolerability. - Myth: This medicine causes weight gain.
Fact: Dapagliflozin may actually promote modest weight loss. Metformin is weight-neutral.
🔄 Alternative Options
Generic Alternatives
- Dapagliflozin + Metformin generic tablets
Brand Alternatives
- Dapanorm-M 5mg/500mg Tablet