gemrich d3 tablet - Calcium Citrate Malate (250mg) + Vitamin D3 (100IU) medicine

Gemrich D3 Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Gonan Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category This medicine is generally considered safe during pregnancy when taken as directed. Adequate calcium and vitamin D intake is essential for fetal bone development. Consult your doctor for appropriate dosing. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for calcium and vitamin D supplementation.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe nausea, vomiting, or abdominal pain
  • Confusion or lethargy
  • Increased thirst and frequent urination
  • Blood in urine or severe flank pain
  • Rash, itching, or swelling of face, lips, or throat
  • Irregular heartbeat or palpitations

If experiencing severe symptoms, call emergency services immediately.

What is gemrich d3 tablet used for?

This medicine is a calcium and vitamin D3 supplement used to treat calcium deficiency and support bone health. It is taken orally, usually once daily with food.

  • Generic Name: Calcium Citrate Malate (250mg) + Vitamin D3 (100IU)
  • Manufacturer: Gonan Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gemrich d3 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा कैल्शियम और विटामिन डी3 का संयोजन है, जो हड्डियों की मजबूती के लिए आवश्यक है। इसका उपयोग कैल्शियम की कमी, ऑस्टियोपोरोसिस, और गर्भावस्था के दौरान पोषण संबंधी जरूरतों को पूरा करने के लिए किया जाता है। यह हड्डियों के विकास और रखरखाव में मदद करता है।

साइड इफेक्ट्स: आमतौर पर यह दवा सुरक्षित मानी जाती है, लेकिन कुछ लोगों को कब्ज, पेट फूलना, मतली या पेट में गड़बड़ी हो सकती है। दुर्लभ मामलों में हाइपरकैल्सीमिया या गुर्दे की पथरी हो सकती है। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इसे भोजन के साथ लें ताकि अवशोषण बेहतर हो और पेट की परेशानी कम हो। अनुशंसित खुराक से अधिक न लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 gemrich d3 tablet Uses & Benefits

[{"condition":"Calcium deficiency","description":"Used to prevent and treat calcium deficiency when dietary intake is inadequate.","evidence":"Well-established"},{"condition":"Osteoporosis prevention and treatment","description":"Supports bone mineral density and reduces fracture risk when combined with adequate vitamin D.","evidence":"Well-established"},{"condition":"Pregnancy and lactation","description":"Provides supplemental calcium and vitamin D to meet increased demands during pregnancy and breastfeeding.","evidence":"Well-established"},{"condition":"Postmenopausal women","description":"Helps maintain bone health in postmenopausal women at risk of osteoporosis.","evidence":"Well-established"},{"condition":"Malabsorption syndromes","description":"Beneficial for individuals with conditions that impair calcium absorption, such as celiac disease or inflammatory bowel disease.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Premenstrual syndrome (PMS)","description":"Calcium supplementation may help reduce PMS symptoms, though not a primary indication.","evidence":"Limited"},{"condition":"Colorectal cancer prevention","description":"Some studies suggest calcium may reduce colorectal cancer risk, but evidence is not conclusive.","evidence":"Limited"}]

Primary treatment for: Calcium deficiency

Also treats: Osteoporosis, Osteomalacia, Rickets, Hypoparathyroidism

📋 Drug Information

Generic Name(s)Calcium Citrate Malate (250mg) + Vitamin D3 (100IU)
Brand Namegemrich d3 tablet
ManufacturerGonan Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to enhance absorption and reduce stomach upset.
2
Maintain adequate hydration while taking this supplement.
3
Avoid taking this medicine with iron, zinc, or certain antibiotics; separate by at least 2 hours.
4
Do not exceed the recommended dose without consulting your doctor.
5
Inform your doctor if you have a history of kidney stones or kidney disease.
6
Regular monitoring of calcium levels may be needed during long-term use.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Bone pain
This medicine is commonly prescribed for calcium deficiency-related bone pain.
Likely Use
✅
Muscle cramps
Calcium and vitamin D supplementation can help relieve muscle cramps due to deficiency.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCalcium citrate malate is absorbed efficiently in the small intestine, and its absorption is enhanced by vitamin D3. The presence of food may improve tolerability but does not significantly affect overall absorption.
DistributionCalcium is distributed primarily to bones and teeth, with smaller amounts in extracellular fluids and soft tissues. Vitamin D3 is distributed to various tissues, including bone, intestine, kidney, and liver.
Protein BindingCalcium is approximately 40% bound to plasma proteins, mainly albumin. Vitamin D3 and its metabolites are highly bound to vitamin D-binding protein.
MetabolismVitamin D3 is metabolized in the liver to 25-hydroxyvitamin D and further in the kidneys to 1,25-dihydroxyvitamin D. Calcium is not metabolized.
Half-LifeThe half-life of vitamin D3 is approximately 15 days, while calcium is eliminated via renal and fecal routes with a half-life of several hours.
ExcretionExcess calcium is excreted primarily in urine and feces. Vitamin D metabolites are excreted mainly in bile and urine.
BioavailabilityCalcium citrate malate has high bioavailability, especially when taken with food. Vitamin D3 bioavailability is enhanced by dietary fats.
Onset of ActionEffects on calcium absorption begin within hours, but improvements in bone density may take weeks to months.
Peak Plasma TimePeak serum calcium levels occur 2-4 hours after oral administration. Vitamin D3 peak levels are reached after several hours.
Duration of ActionThe effects on calcium homeostasis last for about 24 hours, but bone health benefits require continuous supplementation.

How It Works

This medicine works by providing two essential nutrients: calcium and vitamin D3. Calcium citrate malate is a highly bioavailable form of calcium that directly supplies the mineral needed for bone mineralization, muscle contraction, nerve signaling, and blood clotting. Vitamin D3 (cholecalciferol) acts as a hormone precursor that enhances intestinal calcium absorption by increasing the synthesis of calcium-binding proteins in the gut. It also promotes renal calcium reabsorption and mobilizes calcium from bone when needed. Together, they maintain calcium homeostasis and support skeletal health.

Mechanism Steps

1
Calcium absorption: Calcium citrate malate dissociates in the stomach, releasing calcium ions that are absorbed primarily in the small intestine.
2
Vitamin D3 activation: Vitamin D3 is converted in the liver to 25-hydroxyvitamin D and then in the kidneys to its active form, 1,25-dihydroxyvitamin D.
3
Enhanced calcium uptake: Active vitamin D increases the expression of calcium transport proteins in the intestinal lining, boosting calcium absorption.
4
Bone mineralization: Calcium and phosphate combine to form hydroxyapatite crystals, which are deposited in bone matrix, increasing bone strength.
5
Calcium homeostasis: Vitamin D and parathyroid hormone regulate blood calcium levels by controlling absorption, excretion, and bone resorption.

💡 How to Take gemrich d3 tablet

Strength: Calcium Citrate Malate 250mg + Vitamin D3 100IU immediate-release tablet.

1Take the tablet orally with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food to enhance absorption and reduce stomach upset.
4Follow the dosage schedule prescribed by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet daily or as directed by a physician. The dose may be adjusted based on individual needs, such as age, dietary intake, and medical condition. It is best taken with meals to enhance absorption and reduce gastrointestinal upset. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require lower doses due to reduced renal function. Consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be necessary in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Consult a doctor.
Maximum Daily DoseThe maximum daily dose should not exceed the recommended amount unless prescribed by a doctor. Typically, one tablet daily is sufficient.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Enhances absorption and reduces stomach upset.
Oxalate-rich foods (spinach, rhubarb)
Avoid taking at the same time
Oxalates can bind calcium and reduce absorption.
Phytate-rich foods (whole grains, legumes)
Separate by 2 hours
Phytates can interfere with calcium absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gemrich d3 tablet

✅ Common Side Effects

Constipation (Common (5-10%))
Increase dietary fiber and fluid intake. Consult doctor if persistent.
Bloating (Common (5-10%))
Take with food and stay hydrated. Usually resolves on its own.
Nausea (Uncommon (1-5%))
Take with meals to reduce nausea. Consult doctor if severe.
Stomach upset (Uncommon (1-5%))
Take with a full glass of water and food. If persists, consult doctor.

🚨 Serious Side Effects

Hypercalcemia (Rare (<0.1%))
Seek immediate medical attention if you experience nausea, vomiting, confusion, or increased thirst.
Kidney stones (Rare (<0.1%))
Report severe flank pain or blood in urine to your doctor immediately.
Allergic reaction (Rare (<0.1%))
Seek emergency help if you notice rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hypercalciuria
Regular monitoring may be needed. Consult doctor if symptoms occur.
Soft tissue calcification
Requires medical evaluation and dose adjustment.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Thiazide diuretics Major
Digoxin Major
Tetracycline Major
Fluoroquinolones Major
Iron supplements Moderate
Zinc supplements Moderate
Levothyroxine Moderate
Corticosteroids Minor
Laxatives Minor
Alcohol Moderate

🚨 Major Interactions

  • Thiazide diuretics
  • Digoxin
  • Tetracycline antibiotics
  • Fluoroquinolone antibiotics

⚡ Moderate Interactions

  • Iron supplements
  • Zinc supplements
  • Levothyroxine

🍷 Alcohol Interaction

Alcohol may impair calcium absorption and increase the risk of bone loss. It is advisable to limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypercalcemia","Hypercalciuria","Severe renal impairment","Hypersensitivity to any component","Active kidney stones"]

⚠️ Warnings & Precautions

["Use with caution in patients with a history of kidney stones.","Avoid concurrent use with other calcium or vitamin D supplements without medical advice.","Monitor calcium levels during long-term therapy.","Not recommended for patients with sarcoidosis due to risk of hypercalcemia.","Consult doctor before use in patients with heart disease or on digoxin."]

🤱 Lactation Safety

This medicine is compatible with breastfeeding. Calcium and vitamin D are excreted in breast milk and are safe for the infant. Consult your doctor for proper dosage.

💊 Overdose Management

Overdose may cause hypercalcemia, leading to symptoms such as nausea, vomiting, confusion, and increased thirst. Seek immediate medical attention. Treatment may include discontinuation of the supplement, hydration, and medications to lower calcium levels.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have a history of kidney stones, kidney disease, heart disease, or high calcium levels. Do not exceed the recommended dose without medical advice. Take this medicine with a full glass of water, preferably with meals, to enhance absorption and reduce stomach upset. Avoid taking it at the same time as iron supplements, zinc, or certain antibiotics (like tetracyclines and fluoroquinolones) as calcium can interfere with their absorption; separate these by at least 2 hours. If you are pregnant or breastfeeding, consult your doctor before use. This medicine may interact with thiazide diuretics, digoxin, and other medications; always provide a complete list of your medications to your healthcare provider. Regular monitoring of calcium levels may be necessary during long-term therapy. Keep out of reach of children. Do not use if the seal is broken or if the expiry date has passed. Store in a cool, dry place away from direct sunlight. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and may require lower doses. Regular monitoring of calcium and vitamin D levels is recommended.

🤰 Pregnancy Planning (TTC)

Ensure adequate calcium and vitamin D intake before and during pregnancy. Consult your doctor for appropriate supplementation.

🏥 Post-Surgery Considerations

Calcium and vitamin D supplementation may be beneficial for bone healing after surgery. Consult your doctor for personalized advice.

🦷 Dental Procedures

No specific precautions are needed for dental procedures. Inform your dentist about all medications you are taking.

💚 Lifestyle Tips for Better Results

🏃
Maintain a balanced diet rich in calcium and vitamin D.
🥗
Engage in weight-bearing exercises to strengthen bones.
😴
Avoid smoking and limit alcohol consumption.
💧
Get adequate sunlight exposure for natural vitamin D synthesis.
🧘
Stay hydrated to support kidney function.

🏋️ Exercise Considerations

No specific exercise restrictions are associated with this medicine. However, if you have bone or joint pain, consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include dairy products, leafy greens, and fortified foods.
Consume fatty fish for vitamin D.
Limit caffeine and alcohol intake.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine does not typically affect your ability to drive or operate machinery. However, if you experience dizziness or unusual symptoms, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, especially if it was prescribed for a specific condition. If you experience severe side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine at recommended doses is generally safe. However, excessive intake may lead to hypercalcemia or kidney stones. Regular monitoring of calcium levels and renal function is advised for individuals on prolonged therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary calcium

Increasing intake of calcium-rich foods can help maintain bone health.

Evidence: Well-established
Sunlight exposure

Regular sunlight exposure helps the body synthesize vitamin D.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions between this medicine and vaccines. Continue with your regular vaccination schedule.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking it at your usual time or adjust gradually. Check customs regulations for supplements before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old postmenopausal woman with osteopenia
She was prescribed this medicine to support bone health. After 6 months of consistent use along with dietary changes, her bone density improved slightly. She reported mild constipation initially, which resolved after increasing fiber intake.
💡 Lesson: Consistency and lifestyle modifications enhance the benefits of calcium and vitamin D supplementation.
👤 A 30-year-old pregnant woman in her second trimester
Her doctor recommended this medicine to meet increased calcium demands. She took it with breakfast daily and experienced no side effects. Her calcium levels remained normal throughout pregnancy.
💡 Lesson: Calcium and vitamin D supplementation is safe and beneficial during pregnancy when taken as directed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvements in calcium levels may be seen within days, but bone health benefits take weeks to months of consistent use.

Q: Can I take it on an empty stomach?

A: It is best taken with food to enhance absorption and reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I take it with other medications?
  • What if I miss a dose?
  • Is it safe during pregnancy?
  • Does it cause weight gain?

🔄 Substitutes for gemrich d3 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Calcium supplements can cause kidney stones in everyone.
    Fact: Kidney stones are rare and usually occur with excessive doses or pre-existing risk factors.
  • Myth: Vitamin D3 is only for bone health.
    Fact: Vitamin D3 also supports immune function, muscle health, and mood regulation.

🔄 Alternative Options

Generic Alternatives

  • Calcium Citrate Malate + Vitamin D3 tablets

Brand Alternatives

  • Gemrich D3 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Calcium Citrate Malate + Vitamin D3","key_difference":"Highly bioavailable form of calcium, less dependent on stomach acid."},{"medicine":"Calcium Carbonate + Vitamin D3","key_difference":"Requires stomach acid for absorption, may cause more GI side effects."}]

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