gdc 100mg/4mg/2mg/10mg tablet - Guaifenesin (100mg) + Bromhexine (4mg) medicine

GDC 100mg/4mg Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Lexicon Biotech India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for symptomatic relief of productive cough.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in your cough or sputum.
  • Severe chest pain or difficulty breathing.
  • High fever (above 101°F) that lasts more than 3 days.
  • Cough lasting more than 7 days without improvement.
  • Swelling of your face, lips, tongue, or throat.
  • Severe dizziness or fainting.
  • Rash or hives covering your body.
  • Coughing up large amounts of blood.

If experiencing severe symptoms, call emergency services immediately.

What is gdc 100mg/4mg/2mg/10mg tablet used for?

This medicine is a combination of guaifenesin and bromhexine used to treat productive cough by thinning mucus and making it easier to cough out. It is taken orally, usually 1 tablet 2-3 times a day, and should not be used for more than 7 days without medical advice.

  • Generic Name: Guaifenesin (100mg) + Bromhexine (4mg)
  • Manufacturer: Lexicon Biotech India Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gdc 100mg/4mg/2mg/10mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा गुआइफेनेसिन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी के इलाज के लिए किया जाता है। यह बलगम को पतला करके उसे बाहर निकालने में मदद करती है। यह आमतौर पर सर्दी, ब्रोंकाइटिस और अन्य श्वसन संक्रमणों में होने वाली गाढ़ी बलगम वाली खांसी में राहत देती है। यह दवा खांसी को रोकती नहीं है, बल्कि बलगम को बाहर निकालने में सहायता करती है। इसे डॉक्टर की सलाह के अनुसार ही लें और 7 दिनों से अधिक न लें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट में परेशानी और सिरदर्द शामिल हो सकते हैं। कुछ लोगों को चक्कर आना या नींद आना भी महसूस हो सकता है। ये दुष्प्रभाव आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। यदि आपको त्वचा पर चकत्ते, खुजली, सूजन, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या गर्भधारण की योजना बना रही हैं, तो डॉक्टर से सलाह लें। इस दवा को लेते समय शराब का सेवन न करें। यदि खांसी 7 दिनों से अधिक रहती है, बुखार, दाने, या लगातार सिरदर्द हो, तो दवा बंद करें और डॉक्टर से मिलें। दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 gdc 100mg/4mg/2mg/10mg tablet Uses & Benefits

[{"condition":"Productive cough (wet cough)","description":"Helps loosen and thin mucus in the airways, making it easier to cough out and providing symptomatic relief.","evidence":"Well-established for symptomatic relief"},{"condition":"Acute bronchitis","description":"Used as an adjunct to help clear mucus from the airways during acute bronchitis.","evidence":"Commonly used, evidence supportive"},{"condition":"Chronic bronchitis","description":"May help manage chronic mucus hypersecretion in conditions like chronic bronchitis.","evidence":"Limited evidence, used symptomatically"},{"condition":"Common cold with chest congestion","description":"Provides relief from chest congestion by thinning mucus, though it does not treat the viral infection itself.","evidence":"Commonly used for symptom relief"}]

Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to help thin mucus in sinus passages, but not a primary treatment.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally used to help clear middle ear fluid, but evidence is weak.","evidence":"Insufficient"}]

Primary treatment for: Productive cough

Also treats: Acute bronchitis, Chronic bronchitis, Common cold with chest congestion

📋 Drug Information

Generic Name(s)Guaifenesin (100mg) + Bromhexine (4mg)
Brand Namegdc 100mg/4mg/2mg/10mg tablet
ManufacturerLexicon Biotech India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce the chance of stomach upset.
2
Drink plenty of water throughout the day to help loosen mucus and make coughing more productive.
3
Do not use this medicine for more than 7 days without consulting your doctor.
4
Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause dizziness.
5
If you are taking any other cough or cold medicine, check with your doctor or pharmacist before combining them.
6
Do not exceed the recommended dose; taking more will not provide faster relief and may increase side effects.
7
If your cough is accompanied by high fever, rash, or persistent headache, stop the medicine and seek medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough and may not be appropriate.
Not Primary
✅
Chest congestion
Helps loosen mucus and relieve congestion.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

This medicine combines two active ingredients with complementary actions. Guaifenesin is an expectorant that works by increasing the volume and reducing the viscosity of mucus in the respiratory tract. It does this by drawing water into the mucus, making it thinner and easier to cough up. Bromhexine is a mucolytic that works by breaking down the chemical bonds in mucus, further reducing its thickness and stickiness. Together, they help clear the airways of thick, tenacious mucus, providing symptomatic relief from a productive cough. They do not suppress the cough reflex and are not intended to treat the underlying cause of the cough.

Mechanism Steps

1
Guaifenesin increases mucus hydration: Guaifenesin is thought to increase the water content of mucus by stimulating secretions from the respiratory tract, making the mucus less viscous.
2
Bromhexine breaks down mucus structure: Bromhexine works by breaking down the acidic mucopolysaccharide fibers in mucus, reducing its stickiness and thickness.
3
Enhanced mucus clearance: The combined effect makes it easier for the patient to cough out the loosened mucus, helping to clear the airways.

💡 How to Take gdc 100mg/4mg/2mg/10mg tablet

Strength: Each tablet contains Guaifenesin 100 mg and Bromhexine 4 mg.

1Swallow the tablet whole with a glass of water.
2Take it with food or milk to prevent stomach upset.
3Do not crush, chew, or break the tablet unless advised by your doctor.
4Follow the dosage schedule prescribed by your doctor.
5Drink plenty of fluids while taking this medicine to help loosen mucus.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1 tablet taken orally 2 to 3 times a day, or as directed by your physician. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be needed in patients with severe kidney impairment. Consult your doctor.
Hepatic ImpairmentDose adjustment may be needed in patients with severe liver impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets in 24 hours, or as prescribed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals or snacks
Reduces stomach upset and nausea.
Water
Drink plenty of fluids
Helps thin mucus and makes coughing more productive.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gdc 100mg/4mg/2mg/10mg tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food or milk to reduce stomach upset. If it persists, consult your doctor.
Vomiting (Common (1-10%))
Stay hydrated with small sips of water. If vomiting is severe or persistent, contact your doctor.
Diarrhea (Common (1-10%))
Drink plenty of fluids to prevent dehydration. Avoid fatty or spicy foods. Consult doctor if it lasts more than a few days.
Stomach discomfort (Common (1-10%))
Take the medicine with a meal or snack. If discomfort continues, speak to your doctor.
Headache (Common (1-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Stop the medicine and seek immediate medical attention if you develop a painful rash, blistering, or peeling skin.
Bronchospasm (Rare)
Seek immediate medical help if you experience wheezing, chest tightness, or difficulty breathing.

⚠️ Rare Side Effects

Dizziness
Avoid driving or operating machinery until you feel normal. If dizziness persists, consult your doctor.
Drowsiness
Avoid activities requiring alertness. Consult your doctor if it interferes with daily activities.
Increased heart rate
Report to your doctor if you notice a persistent fast heartbeat.
Tremors
Consult your doctor if you experience uncontrolled shaking.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Codeine Major
Dextromethorphan Major
MAOIs Major
Atropine Moderate
Antihistamines Moderate
Amoxicillin Moderate
Tetracycline Moderate
Diuretics Minor

🚨 Major Interactions

  • Cough suppressants (e.g., codeine, dextromethorphan)
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, antihistamines)
  • Antibiotics (e.g., amoxicillin, tetracycline)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and stomach upset while taking this medicine. It is advisable to avoid alcohol during treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to guaifenesin, bromhexine, or any other ingredient in this medicine.","Children under 2 years of age (due to risk of severe side effects).","Active peptic ulcer disease."]

⚠️ Warnings & Precautions

["Do not use for a chronic cough that persists for more than 7 days, or for a cough accompanied by excessive phlegm, fever, rash, or persistent headache, unless directed by a doctor.","Use with caution in patients with a history of stomach ulcers.","Use with caution in patients with severe liver or kidney impairment.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not exceed the recommended dose.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention or contact a poison control center. Symptoms of overdose may include nausea, vomiting, diarrhea, and abdominal discomfort. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also, tell your doctor about any medical conditions you have, especially stomach ulcers, liver disease, kidney disease, or heart problems. Do not take this medicine for more than the recommended duration without consulting a doctor. If your cough persists for more than a week, recurs, or is accompanied by fever, rash, or persistent headache, stop taking this medicine and seek medical advice. Avoid drinking alcohol while taking this medicine as it may increase drowsiness and dizziness. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of the reach of children. Store it in a cool, dry place away from direct sunlight. Always check the expiry date before use and do not use if expired. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, particularly dizziness, drowsiness, and confusion. They may also have reduced kidney or liver function, which can affect drug clearance. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the potential benefits against any possible risks.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, inform your surgeon or anesthesiologist that you are taking this medicine. It may interact with other medications used during or after surgery. Do not restart this medicine after surgery without your doctor's approval.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental work. Also, if you are taking other medications, there could be interactions.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water and warm fluids.
🥗
Use a humidifier or take steamy showers to help loosen mucus.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body recover.
🧘
Practice good hand hygiene to prevent spreading infections.
🌞
Use a saline nasal spray to help clear nasal congestion.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require balance and alertness until you know how the medicine affects you. Light activity like walking is generally safe if you feel up to it.

🥗 Diet Recommendations

Drink warm fluids like herbal tea, soup, and warm water with honey.
Include foods rich in vitamin C like oranges, lemons, and bell peppers.
Avoid cold, sugary, and processed foods that can thicken mucus.
Eat light, easily digestible meals.
Avoid dairy products if they seem to increase mucus thickness for you.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. If affected, avoid driving, operating machinery, or performing tasks that require mental alertness. Most people can continue their usual activities, but take precautions until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, if it comes back, or if you experience fever, rash, or persistent headache. Also stop if you experience any severe side effects or allergic reactions.

📅 Long-Term Use Effects

This medicine is intended for short-term use only. Long-term use is not recommended without medical supervision. Prolonged use may mask underlying conditions and delay proper diagnosis. If your cough persists for more than 7 days, consult a doctor to rule out serious conditions. There is no established benefit of long-term use for chronic cough without a specific diagnosis.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and soothe irritated airways.

Evidence: Commonly used, supportive evidence
Saline nasal irrigation

Using a saline solution to rinse nasal passages can help clear congestion.

Evidence: Well-established for nasal congestion
Honey

A spoonful of honey can help soothe cough, especially at night.

Evidence: Some evidence for cough relief

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccination, inform your healthcare provider that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking the medicine at the same intervals as prescribed, but adjust to local time gradually. Keep it in your carry-on luggage if flying, and check customs regulations for your destination. Do not leave it in a hot car or checked baggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He had a persistent wet cough with thick yellow mucus for 4 days. His doctor prescribed this medicine along with rest and fluids. He took it three times a day with meals. By day 3, his cough became more productive and easier to manage. He completed the 5-day course and recovered fully.
💡 Lesson: Taking this medicine with food and staying hydrated helps loosen mucus and improves cough clearance.
👤 A 50-year-old woman with chronic bronchitis
She experienced frequent episodes of chest congestion and difficulty coughing out mucus. Her doctor recommended this medicine for short-term symptom relief during flare-ups. She found it helpful but was advised not to use it continuously. She also quit smoking and started breathing exercises.
💡 Lesson: This medicine provides symptomatic relief but should be used short-term. Lifestyle changes like smoking cessation are crucial for long-term management.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts providing relief within a few hours to a day, but the full effect may take 1-2 days. It works by thinning mucus, making it easier to cough out.

Q: Can I take this medicine on an empty stomach?

A: It is best to take this medicine with food or milk to reduce the risk of stomach upset. If you take it on an empty stomach and experience nausea, try taking it with a snack next time.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children under 2 years of age. For older children, consult a pediatrician for appropriate dosing and safety.

Q: Can I take this medicine with other cough medicines?

A: You should avoid taking this medicine with cough suppressants (like codeine or dextromethorphan) as they have opposing effects. Always consult your doctor or pharmacist before combining any medications.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for my child?
  • Can I take it with antibiotics?

🔄 Substitutes for gdc 100mg/4mg/2mg/10mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for productive cough with mucus. It is not effective for dry cough and may be harmful if used inappropriately.
  • Myth: It is safe to take this medicine for weeks.
    Fact: This medicine is for short-term use. If cough persists beyond 7 days, consult a doctor.
  • Myth: More medicine means faster relief.
    Fact: Taking more than the recommended dose can increase side effects without providing extra benefit.

🔄 Alternative Options

Generic Alternatives

  • Guaifenesin + Bromhexine tablet (various manufacturers)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Guaifenesin + Bromhexine)","composition":"Guaifenesin 100 mg + Bromhexine 4 mg","primary_use":"Productive cough","notes":"Combines expectorant and mucolytic."},{"medicine":"Ambroxol + Guaifenesin","composition":"Ambroxol + Guaifenesin","primary_use":"Productive cough","notes":"Ambroxol is a metabolite of bromhexine with similar effects."},{"medicine":"Bromhexine + Dextromethorphan","composition":"Bromhexine + Dextromethorphan","primary_use":"Cough with mucus","notes":"Combines mucolytic with cough suppressant; used when cough is exhausting."}]

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