Ascoril Expectorant: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of face, lips, tongue, or throat
- Severe rash, blistering, or peeling skin
- Blood in sputum or vomit
- Severe abdominal pain or persistent vomiting
- Yellowing of skin or eyes
- Decreased urine output or severe flank pain
- High fever with chills
If experiencing severe symptoms, call emergency services immediately.
What is cofgo syrup used for?
This medicine is a combination of Bromhexine and Guaifenesin used to treat productive cough by thinning mucus and making it easier to cough out. It is taken orally every 4-6 hours as needed, but only under medical advice.
- Generic Name: Bromhexine + Guaifenesin
- Manufacturer: LA Grande Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cofgo syrup के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोमहेक्सिन और ग्वाइफेनेसिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी के इलाज के लिए किया जाता है। यह गले और फेफड़ों में जमा गाढ़े बलगम को पतला करके बाहर निकालने में मदद करती है। यह आमतौर पर तीव्र ब्रोंकाइटिस, सर्दी-जुकाम और अन्य श्वसन संक्रमणों में राहत के लिए दी जाती है। यह सूखी खांसी के लिए नहीं है। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, दस्त, पेट में असहजता और सिरदर्द शामिल हैं। कुछ लोगों को चक्कर आना या नींद आना भी महसूस हो सकता है। दुर्लभ मामलों में गंभीर एलर्जी प्रतिक्रिया हो सकती है, जैसे चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। निर्धारित मात्रा से अधिक न लें। दवा लेते समय खूब पानी पिएं। अगर आपको चक्कर या नींद आती है तो वाहन चलाने या मशीन चलाने से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। दवा को ठंडी और सूखी जगह पर रखें।
💊 cofgo syrup Uses & Benefits
[{"condition":"Productive cough associated with acute bronchitis","description":"Helps loosen thick mucus and makes cough more productive, providing symptomatic relief.","evidence":"Well-established"},{"condition":"Productive cough due to common cold","description":"Used to reduce chest congestion and ease expectoration in viral upper respiratory infections.","evidence":"Commonly used"},{"condition":"Chronic obstructive pulmonary disease (COPD) with thick secretions","description":"May help in clearing airway secretions as an adjunct to other therapies.","evidence":"Limited"},{"condition":"Bronchiectasis with excessive mucus","description":"Sometimes used to aid mucus clearance in patients with bronchiectasis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sinusitis with thick nasal discharge","description":"Occasionally used off-label to thin nasal secretions and relieve sinus congestion.","evidence":"Limited"},{"condition":"Post-operative atelectasis prevention","description":"Rarely used off-label to help clear secretions after surgery, but evidence is insufficient.","evidence":"Insufficient"}]
Primary treatment for: Productive cough
Also treats: Acute bronchitis, Common cold, COPD, Bronchiectasis
📋 Drug Information
| Generic Name(s) | Bromhexine + Guaifenesin |
| Brand Name | Ascoril Plus Expectorant |
| Manufacturer | LA Grande Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Mucolytic and Expectorant |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from direct sunlight and moisture. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two mucoactive agents with complementary actions. Bromhexine is a mucolytic that reduces the viscosity of mucus by breaking down acidic mucopolysaccharide fibers, thereby thinning secretions. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions by increasing hydration, which helps cilia move mucus more effectively. Together, they make coughs more productive and ease the removal of mucus from the airways.
Mechanism Steps
💡 How to Take cofgo syrup
Strength: Each 5 mL of oral liquid contains Bromhexine 4 mg and Guaifenesin 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mL (containing Bromhexine 4 mg and Guaifenesin 100 mg) taken orally every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and other medications being taken. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Use with caution and consult a doctor for dose adjustment based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose for adults is 24 mL (containing Bromhexine 24 mg and Guaifenesin 600 mg) in divided doses, but this must be confirmed by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cofgo syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| MAOIs | Major | |
| Anticholinergics | Moderate | |
| CNS depressants | Moderate | |
| Antacids | Minor | |
| Diuretics | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Warfarin
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine)
- CNS depressants (e.g., benzodiazepines, opioids)
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and stomach upset while taking this medicine. It is advisable to avoid alcohol or limit intake during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Bromhexine, Guaifenesin, or any component of the formulation","Active peptic ulcer disease","Severe hepatic impairment","Severe renal impairment","Children under 2 years of age","Use with MAOIs"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose or duration of use.","Consult a doctor if cough persists for more than 7 days, or if it is accompanied by fever, rash, or persistent headache.","Avoid driving or operating machinery if you experience dizziness or drowsiness.","Use with caution in patients with asthma or COPD; consult a doctor before use.","Not recommended for chronic cough unless advised by a doctor.","Keep out of reach of children.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not use with other cough and cold medicines without medical advice."]
🤱 Lactation Safety
It is not known whether Bromhexine and Guaifenesin are excreted in human breast milk. Consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal discomfort. In severe cases, dizziness, drowsiness, and hypotension may occur. There is no specific antidote. Treatment is supportive and symptomatic. Seek immediate medical attention if overdose is suspected. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of use. Drink plenty of water while taking this medicine to help loosen mucus. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not take this medicine with other cough and cold products that contain similar ingredients unless advised by a doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use it after the expiry date. If your cough persists for more than 7 days, or if you develop fever, rash, or persistent headache, stop the medicine and consult your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, drowsiness, and gastrointestinal upset. Use with caution and consult a doctor for dose adjustment based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed and after medical advice.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your doctor. It may help clear secretions, but caution is needed if you have difficulty coughing due to pain. Follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental work. No major interactions are expected, but your dentist should be aware.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have a productive cough or feel unwell. Light activity like walking may be fine, but consult your doctor before resuming intense workouts. If you experience dizziness or shortness of breath, stop exercising and seek medical advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Otherwise, it does not significantly impact daily work life.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, or if you develop fever, rash, persistent headache, or any severe side effects. Do not stop abruptly if you have been on it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless advised by a doctor. Prolonged use may increase the risk of kidney stones due to Guaifenesin and may cause liver enzyme changes. Regular monitoring of kidney and liver function may be required if used for extended periods. Always consult your doctor before using it for more than 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve chest congestion naturally.
Evidence: Well-establishedCan help clear nasal passages and reduce postnasal drip.
Evidence: Well-establishedSoothes the throat and may reduce cough frequency.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage if you need it during the flight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose.
A: Generally yes, but consult your doctor as some antibiotics may interact. Always inform your doctor about all medicines you are taking.
A: It is not recommended for children under 2 years. For older children, consult a pediatrician for appropriate dosing.
A: Yes, but if it causes drowsiness, take it earlier in the evening. Follow your doctor's advice.
🤔 Common Patient Concerns
🔄 Substitutes for cofgo syrup
View AllAlternative brands with exact same active ingredient:
-
cufed expectorantAdcco Limited ₹24.00 38.5% CHEAPER
-
gdc 100mg/4mg/2mg/10mg tabletLexicon Biotech India Ltd ₹27.00 30.8% CHEAPER
-
brorex plus expectorantMedihands Pharmaceuticals ₹29.06 25.5% CHEAPER
-
brometh syrupHealth Guard India Pvt Ltd ₹36.56 6.3% CHEAPER
-
alcoryl syrupAlice Healthcare Pvt Ltd ₹39.00 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: It is only effective for productive cough with thick mucus. It is not for dry cough. - Myth: It is safe to take this medicine for weeks without doctor supervision.
Fact: Prolonged use should be avoided unless advised by a doctor. It may cause side effects. - Myth: More medicine means faster relief.
Fact: Taking more than the recommended dose can be harmful and does not speed up recovery.
🔄 Alternative Options
Generic Alternatives
- Bromhexine + Guaifenesin oral solution
- Bromhexine + Guaifenesin syrup
Brand Alternatives
- Ascoril Expectorant
- Ascoril LS
- Ascoril D
- Cheston
- Mucolite
- Grilinctus