gasfree tablet - Pancreatin (175mg) + Simethicone (50mg) medicine

G-On Plus Tablet: Complete Medicine Guide

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🏭 Wilymed Pharmaceuticals Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Established for pancreatic enzyme replacement; limited for simethicone in combination.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe abdominal pain
  • Blood in vomit or stool
  • Persistent vomiting
  • Signs of allergic reaction like rash or itching
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is gasfree tablet used for?

This medicine is a combination of Pancreatin 175 mg and Simethicone 50 mg used to treat digestive enzyme deficiency and relieve gas and bloating. It works by replacing missing enzymes and reducing gas bubbles in the gut.

  • Generic Name: Pancreatin (175mg) + Simethicone (50mg)
  • Manufacturer: Wilymed Pharmaceuticals Private Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 gasfree tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पैन्क्रिएटिन और सिमेथिकोन का संयोजन है। यह पाचन एंजाइम की कमी को पूरा करती है और पेट की गैस, सूजन और अपच में राहत देती है। यह भोजन के साथ ली जानी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त या कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी हो सकती है। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। शराब से बचें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 gasfree tablet Uses & Benefits

[{"condition":"Exocrine pancreatic insufficiency","description":"Replaces deficient pancreatic enzymes to improve digestion and absorption of fats, proteins, and carbohydrates.","evidence":"Well-established"},{"condition":"Chronic pancreatitis","description":"Helps manage maldigestion and steatorrhea associated with chronic pancreatitis.","evidence":"Well-established"},{"condition":"Cystic fibrosis","description":"Used as pancreatic enzyme replacement therapy to correct malabsorption in cystic fibrosis patients.","evidence":"Well-established"},{"condition":"Post-gastrectomy or pancreatic surgery","description":"Supports digestion when enzyme production is reduced after surgery.","evidence":"Established"},{"condition":"Functional dyspepsia with bloating","description":"Simethicone component helps relieve gas and bloating; pancreatin may aid digestion.","evidence":"Limited"},{"condition":"Flatulence and abdominal distension","description":"Simethicone reduces surface tension of gas bubbles, providing symptomatic relief.","evidence":"Established"}]

Off-label uses: [{"condition":"Irritable bowel syndrome (IBS) with bloating","description":"Sometimes used to alleviate gas-related symptoms in IBS, though evidence is limited.","evidence":"Limited"},{"condition":"Lactose intolerance","description":"Pancreatin may help digest lactose in some individuals, but not a standard treatment.","evidence":"Weak"}]

Primary treatment for: Exocrine pancreatic insufficiency

Also treats: Chronic pancreatitis, Cystic fibrosis, Flatulence, Functional dyspepsia

📋 Drug Information

Generic Name(s)Pancreatin (175mg) + Simethicone (50mg)
Brand Namegasfree tablet
ManufacturerWilymed Pharmaceuticals Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with meals to mimic natural enzyme release.
2
Swallow the tablet whole; do not crush or chew.
3
Avoid alcohol as it can worsen pancreatic inflammation.
4
Monitor for allergic reactions, especially if you have pork allergy.
5
Consult your doctor if symptoms do not improve within a few days.
6
Do not exceed the prescribed dose.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Bloating and gas
This medicine is commonly prescribed for this.
Likely Use
✅
Steatorrhea (fatty stools)
Pancreatin helps digest fats.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPancreatin enzymes are not absorbed systemically; they act locally in the gastrointestinal lumen. Simethicone is not absorbed from the gastrointestinal tract and is excreted unchanged in feces.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismPancreatin enzymes are proteins and are digested in the gastrointestinal tract like other dietary proteins. Simethicone is not metabolized and is excreted unchanged.
Half-LifeNot established from the available information.
ExcretionSimethicone is excreted unchanged in feces. Pancreatin enzymes are broken down and eliminated via normal protein metabolism.
BioavailabilityNot applicable for pancreatin as it acts locally. Simethicone is not systemically absorbed.
Onset of ActionSimethicone may provide relief within minutes to hours. Pancreatin effects depend on enzyme activity and meal composition.
Peak Plasma TimeNot applicable; neither component is significantly absorbed systemically.
Duration of ActionSimethicone effect lasts until gas bubbles are expelled. Pancreatin acts during the digestive period, typically 1-4 hours after a meal.

How It Works

This medicine combines two active ingredients with complementary actions. Pancreatin provides exogenous pancreatic enzymes (amylase, lipase, protease) that catalyze the hydrolysis of carbohydrates, fats, and proteins in the duodenum, compensating for deficient endogenous enzyme secretion. Simethicone is a silicone polymer that lowers surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce and be expelled more easily, thereby relieving bloating and flatulence.

Mechanism Steps

1
Enzyme supplementation: Pancreatin delivers amylase, lipase, and protease to the small intestine, where they break down carbohydrates, fats, and proteins respectively.
2
Fat digestion: Lipase hydrolyzes triglycerides into fatty acids and monoglycerides, which are absorbed with bile salts.
3
Protein and carbohydrate digestion: Proteases break proteins into peptides and amino acids; amylase converts starches into simpler sugars.
4
Gas bubble reduction: Simethicone reduces surface tension of gas bubbles, causing them to merge and pass out of the body more easily.

💡 How to Take gasfree tablet

Strength: Pancreatin 175 mg + Simethicone 50 mg immediate-release tablet

1Swallow the tablet whole with a glass of water.
2Take it with meals or snacks to aid digestion.
3Do not crush or chew the tablet.
4Follow your doctor's instructions on dosage and frequency.
5If you have difficulty swallowing, consult your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken with each meal or as directed by your doctor. The dose may vary depending on the indication, severity of enzyme deficiency, and individual response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dose adjustment is required for elderly patients, but use with caution and monitor clinical response.
Renal ImpairmentNo specific dose adjustment is established. Use with caution in renal impairment.
Hepatic ImpairmentNo specific dose adjustment is established. Use with caution in hepatic impairment.
Maximum Daily DoseThe maximum daily dose should not exceed the amount prescribed by your doctor. Typically, not more than 3 tablets per day unless directed otherwise.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with meals
Enhances enzyme activity and reduces stomach upset.
Alcohol
Avoid
May worsen pancreatitis and reduce efficacy.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of gasfree tablet

✅ Common Side Effects

Nausea (Common (1-10%))
Take with food and water. If persistent, consult your doctor.
Abdominal discomfort (Common (1-10%))
Usually resolves. Avoid large fatty meals. Consult if severe.
Diarrhea (Common (1-10%))
Stay hydrated. If diarrhea persists beyond 48 hours, seek medical advice.
Constipation (Common (1-10%))
Increase fiber and fluid intake. Consult if no relief.
Vomiting (Uncommon (0.1-1%))
Stop the medicine and consult your doctor if vomiting occurs.

🚨 Serious Side Effects

Allergic reaction (rash, itching, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention. Discontinue the medicine.
Hyperuricemia (elevated uric acid) (Very rare (<0.01%))
Monitor uric acid levels if on high doses. Consult doctor.
Hyperuricosuria (excess uric acid in urine) (Very rare (<0.01%))
Report any joint pain or kidney stones to your doctor.
Severe abdominal pain (Rare (<0.1%))
Seek immediate medical evaluation.

⚠️ Rare Side Effects

Fibrosing colonopathy
Report persistent abdominal pain or changes in bowel habits.
Anaphylaxis
Call emergency services immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Acarbose Major
Miglitol Major
Antacids Moderate
Proton pump inhibitors Moderate
H2 blockers Moderate
Iron supplements Minor
Folic acid Minor

🚨 Major Interactions

  • Acarbose
  • Miglitol

⚡ Moderate Interactions

  • Antacids (calcium carbonate, magnesium hydroxide)
  • Proton pump inhibitors (omeprazole, esomeprazole)
  • H2 blockers (ranitidine, famotidine)

🍷 Alcohol Interaction

Alcohol may exacerbate pancreatic inflammation and reduce the effectiveness of pancreatin. It is advisable to avoid alcohol while taking this medicine, especially if you have a history of pancreatitis.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to pancreatin or simethicone","Acute pancreatitis during the early inflammatory phase","Bowel obstruction or ileus","Known porcine protein allergy"]

⚠️ Warnings & Precautions

["Do not crush or chew the tablet; swallow whole.","Take with meals to ensure optimal enzyme activity.","Avoid alcohol while taking this medicine.","Consult your doctor if symptoms persist or worsen.","Use with caution in patients with renal impairment.","Not recommended for children without medical advice."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

Overdose is unlikely to cause serious effects. However, if you suspect an overdose, contact your doctor or poison control center immediately. Symptoms may include nausea, vomiting, and abdominal pain. Treatment is supportive.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush or chew unless advised. Take it with meals or snacks to help digestion and reduce stomach upset. Do not exceed the recommended dose. Inform your doctor if you have a history of pancreatitis, bowel obstruction, or allergies to pork products. If you are pregnant or breastfeeding, consult your doctor before use. Keep this medicine out of reach of children. Store in a cool, dry place away from direct sunlight. Do not use after the expiry date. If symptoms persist or worsen, seek medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects. Use with caution and monitor renal function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. Safety during pregnancy is not established.

🏥 Post-Surgery Considerations

This medicine may be prescribed after gastrointestinal surgery to aid digestion. Follow your surgeon's instructions.

🦷 Dental Procedures

No specific precautions. Inform your dentist about all medicines you take.

💚 Lifestyle Tips for Better Results

🏃
Eat small, frequent meals to ease digestion.
🥗
Avoid fatty and spicy foods that can trigger symptoms.
😴
Stay hydrated throughout the day.
💧
Limit alcohol consumption.
🧘
Manage stress as it can affect digestion.
🌞
Get regular exercise to support overall health.

🏋️ Exercise Considerations

No specific exercise restrictions. However, if you experience abdominal pain or discomfort, avoid strenuous activities and consult your doctor.

🥗 Diet Recommendations

Include easily digestible foods
Avoid high-fat meals
Eat small, frequent meals
Stay hydrated

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or nausea, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or allergic reactions, stop immediately and seek medical help.

📅 Long-Term Use Effects

Long-term use of pancreatin is generally safe when monitored by a doctor. High doses may rarely cause hyperuricemia. Simethicone is not absorbed and is considered safe for long-term use. Regular monitoring of uric acid levels may be advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary modifications

Eating low-fat, easily digestible meals can help manage symptoms.

Evidence: Well-established
Probiotics

May help improve gut health but not a substitute for enzyme replacement.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, take doses with meals as usual. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old man with chronic pancreatitis
He was prescribed this medicine for maldigestion and bloating. After taking it with meals for two weeks, he noticed significant improvement in digestion and less abdominal discomfort. He emphasized the importance of taking it with food.
💡 Lesson: Consistent use with meals improves efficacy and reduces symptoms.
👤 A 35-year-old woman with functional dyspepsia and gas
She started this medicine as advised by her doctor. Within a few days, her bloating and flatulence reduced. She reported mild nausea initially, which subsided after taking it with food.
💡 Lesson: Taking with food can minimize side effects and enhance benefits.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Simethicone may provide relief within minutes to hours. Pancreatin effects depend on enzyme activity and meal composition.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take, especially acarbose, miglitol, antacids, and proton pump inhibitors.

Q: Is it safe during pregnancy?

A: Consult your doctor before use as safety is not established.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my diabetes medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for gasfree tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken without food.
    Fact: It should be taken with meals for best effect.
  • Myth: It is a painkiller.
    Fact: It is a digestive enzyme and anti-gas medicine, not a painkiller.
  • Myth: It can be taken long-term without doctor supervision.
    Fact: Long-term use should be monitored by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Pancreatin + Simethicone combination tablets from other manufacturers

Brand Alternatives

  • G-On Plus Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Pancreatin alone","difference":"Lacks simethicone, so no anti-gas effect."},{"medicine":"Simethicone alone","difference":"Lacks pancreatin, so no enzyme replacement."}]

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