dizec tablet - Pancreatin (175mg) + Simethicone (25mg) medicine

Dizec Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Glaxo SmithKline Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for symptomatic relief of dyspepsia and bloating; limited for pancreatic insufficiency.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain that does not go away
  • Vomiting blood or material that looks like coffee grounds
  • Black, tarry stools
  • Difficulty breathing or swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Signs of intestinal obstruction such as inability to pass stool or gas with severe bloating

If experiencing severe symptoms, call emergency services immediately.

What is dizec tablet used for?

This medicine is a combination of Pancreatin and Simethicone used to relieve indigestion, bloating, and gas. Pancreatin aids digestion of fats, proteins, and carbohydrates, while Simethicone reduces gas bubbles. It is taken with meals, usually one tablet two to three times daily.

  • Generic Name: Pancreatin (175mg) + Simethicone (25mg)
  • Manufacturer: Glaxo SmithKline Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dizec tablet के बारे में (Hindi Summary)

उपयोग: यह दवा पाचन में सहायता करने और पेट की गैस, सूजन और अपच से राहत देने के लिए इस्तेमाल की जाती है। इसमें पैंक्रिएटिन और सिमेथिकोन होते हैं। पैंक्रिएटिन भोजन को पचाने में मदद करता है, जबकि सिमेथिकोन पेट में बनी गैस के बुलबुले को तोड़कर बाहर निकालने में मदद करता है। इसे आमतौर पर भोजन के साथ लिया जाता है।

साइड इफेक्ट्स: आमतौर पर यह दवा सही तरीके से लेने पर अच्छी तरह सहन की जाती है। कुछ लोगों को हल्का पेट दर्द, जी मिचलाना, दस्त या कब्ज हो सकता है। ये लक्षण आमतौर पर अस्थायी होते हैं। कभी-कभी एलर्जी जैसे दाने, खुजली या सूजन हो सकती है। गंभीर लक्षण होने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर या फार्मासिस्ट की सलाह के अनुसार ही लें। टैबलेट को पानी के साथ पूरा निगलें, भोजन के साथ या तुरंत बाद लें। बिना सलाह के इसे चबाएं या तोड़ें नहीं। दवा की मात्रा न बढ़ाएं। अगर आपको पैंक्रियाटाइटिस, आंतों में रुकावट या पेट की सर्जरी हुई है, तो डॉक्टर को बताएं। बच्चों से दूर रखें। ठंडी और सूखी जगह पर स्टोर करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 dizec tablet Uses & Benefits

[{"condition":"Functional dyspepsia","description":"Helps relieve postprandial fullness, bloating, and upper abdominal discomfort by aiding digestion and reducing gas.","evidence":"Moderate"},{"condition":"Flatulence and bloating","description":"Simethicone reduces gas bubbles, while pancreatin supports breakdown of nutrients, easing distension.","evidence":"Moderate"},{"condition":"Mild exocrine pancreatic insufficiency","description":"Provides supplemental pancreatic enzymes to improve digestion of fats, proteins, and carbohydrates.","evidence":"Limited"},{"condition":"Post-meal indigestion","description":"Used to reduce symptoms of heaviness and discomfort after heavy or fatty meals.","evidence":"Limited"}]

Off-label uses: [{"condition":"Irritable bowel syndrome (IBS) with bloating","description":"Sometimes used to alleviate gas-related symptoms in IBS, though evidence is not strong.","evidence":"Limited"},{"condition":"Chronic pancreatitis symptom relief","description":"May be used as adjunctive therapy for bloating, but not a substitute for proper enzyme replacement.","evidence":"Limited"}]

Primary treatment for: Functional dyspepsia

Also treats: Flatulence, Bloating, Mild exocrine pancreatic insufficiency

📋 Drug Information

Generic Name(s)Pancreatin (175mg) + Simethicone (25mg)
Brand Namedizec tablet
ManufacturerGlaxo SmithKline Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with meals to enhance digestion and reduce stomach upset.
2
Do not exceed the recommended dose of three tablets per day unless advised by your doctor.
3
If symptoms persist beyond seven days, consult your doctor for further evaluation.
4
Avoid taking antacids within two hours of this medicine, as they may reduce its effectiveness.
5
Inform your doctor if you have a history of pancreatitis or bowel obstruction before using this medicine.
6
Keep the tablet in its original packaging and store in a cool, dry place.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Bloating and gas
This medicine is commonly used for these symptoms.
Likely Use
✅
Indigestion after meals
It helps improve digestion and reduce discomfort.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Severe abdominal pain
Seek immediate medical attention; this medicine is not for severe pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPancreatin enzymes are not absorbed systemically; they act locally in the gastrointestinal lumen. Simethicone is not absorbed from the gastrointestinal tract and is excreted unchanged in feces.
DistributionPancreatin enzymes remain in the gastrointestinal tract and are not distributed to body tissues. Simethicone is not absorbed and remains in the gut lumen.
Protein BindingNot applicable, as neither pancreatin nor simethicone is absorbed into the bloodstream to a significant extent.
MetabolismPancreatin enzymes are proteins and are digested by other proteases in the gut if not used. Simethicone is chemically inert and not metabolized.
Half-LifeNot established from the available information.
ExcretionPancreatin enzymes are broken down and excreted in feces. Simethicone is excreted unchanged in feces.
BioavailabilityNot applicable, as the active ingredients act locally in the gastrointestinal tract and are not absorbed systemically.
Onset of ActionSymptomatic relief of bloating may begin within 30 minutes to 1 hour after taking the tablet with a meal.
Peak Plasma TimeNot applicable, as the active ingredients are not absorbed into the bloodstream.
Duration of ActionThe effect generally lasts for 2 to 4 hours, corresponding to the digestive period after a meal.

How It Works

This medicine combines two active ingredients with complementary actions. Pancreatin provides exogenous pancreatic enzymes: amylase breaks down starches into simpler sugars, lipase breaks down fats into fatty acids and glycerol, and protease breaks down proteins into peptides and amino acids. These enzymes work in the alkaline environment of the small intestine to aid digestion. Simethicone is a silicone-based surfactant that lowers the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce and be expelled more easily. Together, they improve digestion and reduce gas-related symptoms.

Mechanism Steps

1
Enzyme release in the stomach: After swallowing, the tablet disintegrates in the stomach, releasing pancreatin and simethicone.
2
Pancreatin enzyme activity: Pancreatic enzymes pass into the small intestine, where they break down fats, proteins, and carbohydrates into absorbable components.
3
Simethicone action on gas: Simethicone reduces surface tension of gas bubbles, allowing them to merge and pass out of the body more easily.
4
Symptom relief: Improved digestion and reduced gas lead to less bloating, fullness, and abdominal discomfort.

💡 How to Take dizec tablet

Strength: Each tablet contains Pancreatin 175 mg and Simethicone 25 mg.

1Swallow the tablet whole with a glass of water.
2Take it with or immediately after a meal.
3Do not crush or chew the tablet.
4Do not take more than the recommended dose.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken two to three times daily with meals, or as directed by your doctor. The dose may vary depending on the severity of symptoms and the underlying condition. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may use this medicine at the same adult dose, but should consult a doctor before starting, especially if they have other medical conditions or are taking multiple medications.
Renal ImpairmentNo dose adjustment is required for renal impairment, as the active ingredients are not absorbed systemically.
Hepatic ImpairmentNo dose adjustment is required for hepatic impairment, as the active ingredients act locally in the gut.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets in 24 hours, unless otherwise directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with food
Enhances digestion and reduces stomach upset.
Alcohol
Avoid
May worsen indigestion and reduce effectiveness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dizec tablet

✅ Common Side Effects

Mild stomach discomfort (Common (1-10%))
Usually resolves on its own. Take with food to minimize.
Nausea (Common (1-10%))
Take with a meal and stay hydrated. Consult doctor if persistent.
Diarrhea (Uncommon (0.1-1%))
Ensure adequate fluid intake. Consult doctor if it continues.
Constipation (Uncommon (0.1-1%))
Increase fiber and water intake. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Intestinal obstruction (Very rare (<0.01%))
Seek immediate medical attention if you have severe abdominal pain, vomiting, and inability to pass stool or gas.
Acute pancreatitis (Very rare (<0.01%))
Seek immediate medical attention if you develop severe upper abdominal pain radiating to back, with nausea and vomiting.

⚠️ Rare Side Effects

Skin rash
Stop the medicine and consult your doctor.
Itching
Stop the medicine and consult your doctor.
Swelling of face or throat
Seek emergency medical help immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids (Al/Mg) Major
Iron supplements Moderate
Omeprazole Moderate
Ranitidine Moderate
Anticholinergics Minor

🚨 Major Interactions

  • Antacids containing aluminum or magnesium
  • Oral iron supplements

⚡ Moderate Interactions

  • Proton pump inhibitors (e.g., omeprazole)
  • H2 blockers (e.g., ranitidine)

🍷 Alcohol Interaction

Alcohol may worsen indigestion and bloating, and can reduce the effectiveness of this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to pancreatin, simethicone, or any component of the tablet","Acute pancreatitis or acute exacerbation of chronic pancreatitis","Intestinal obstruction or suspected bowel obstruction","Children under 12 years without medical advice"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose.","Take with meals for best effect.","Consult a doctor if symptoms persist beyond 7 days.","Avoid use in case of acute pancreatitis.","Inform your doctor if you have a history of bowel surgery or obstruction.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether pancreatin or simethicone passes into breast milk. Consult your doctor before use while breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely to cause serious harm because the ingredients act locally in the gut and are not absorbed. However, if you suspect an overdose, contact your doctor or a poison control center immediately. Symptoms of overdose may include nausea, diarrhea, or abdominal cramps. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember, provided it is still close to the scheduled time. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as advised by your doctor or pharmacist. Swallow the tablet whole with a glass of water, preferably with or just after meals. Do not crush or chew the tablet unless your doctor instructs otherwise. Do not exceed the recommended dose. If you have a history of pancreatitis, bowel obstruction, or abdominal surgery, inform your doctor before using this medicine. Avoid taking antacids containing aluminum or magnesium within two hours of this medicine, as they may reduce its effectiveness. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Do not use this medicine for longer than your doctor recommends without review.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients can take this medicine at the same adult dose. However, they should consult a doctor before use, especially if they have other medical conditions or are taking multiple medications.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

If you have recently undergone abdominal surgery, consult your doctor before using this medicine, as it may not be suitable in some post-operative conditions.

🦷 Dental Procedures

No specific precautions are needed for dental procedures. Inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Eat smaller, more frequent meals to reduce bloating.
🥗
Avoid gas-producing foods like beans, cabbage, and carbonated drinks.
😴
Stay physically active to promote healthy digestion.
💧
Manage stress through relaxation techniques like yoga or meditation.
🧘
Chew your food slowly and thoroughly.
🌞
Stay well hydrated throughout the day.

🏋️ Exercise Considerations

No specific exercise restrictions are required while taking this medicine. However, if you experience abdominal discomfort, avoid strenuous activities until you feel better.

🥗 Diet Recommendations

Include fiber-rich foods like fruits and vegetables.
Avoid fatty and fried foods that can worsen indigestion.
Limit carbonated beverages and caffeine.
Eat yogurt or probiotics to support gut health.
Stay hydrated with water and clear fluids.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. It may help you feel more comfortable at work by reducing bloating and indigestion. If you experience any dizziness or unusual symptoms, avoid driving until you feel better.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as severe abdominal pain, allergic reactions, or signs of intestinal obstruction.

📅 Long-Term Use Effects

Long-term use of this medicine is generally considered safe when taken as directed. However, prolonged use without medical supervision may mask underlying digestive disorders. Regular follow-up with your doctor is recommended if you need to use it for more than a few weeks. There is no known risk of serious long-term toxicity.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding gas-producing foods and eating smaller meals can reduce bloating.

Evidence: Well-established
Probiotics

May help balance gut bacteria and improve digestion.

Evidence: Moderate
Herbal remedies like peppermint oil

May help relax gut muscles and relieve gas.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. You can receive vaccinations while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking it with meals as usual. Check customs regulations for carrying medicines in your destination country. Keep enough supply for the entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with frequent bloating after lunch
Ravi often felt bloated and uncomfortable after eating heavy meals at work. His doctor prescribed this medicine to be taken with lunch. Within a week, he noticed significant relief from bloating and fullness. He also started eating smaller, more frequent meals.
💡 Lesson: Taking this medicine with meals and making dietary adjustments can greatly improve digestive comfort.
👤 A 60-year-old woman with mild pancreatic insufficiency
Mrs. Sharma had difficulty digesting fatty foods and experienced gas and discomfort. Her doctor recommended this medicine with meals. She found that her symptoms improved, especially when she avoided high-fat foods. She continues to follow up with her doctor regularly.
💡 Lesson: This medicine can help manage symptoms of mild pancreatic insufficiency, but dietary changes and regular medical follow-up are important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving bloating and indigestion within 30 minutes to 1 hour after taking it with a meal.

Q: Can I take it on an empty stomach?

A: It is best taken with meals for maximum effectiveness. Taking it on an empty stomach may reduce its benefits.

Q: Is it safe to take daily?

A: It can be taken daily for short periods as directed by your doctor. Long-term use should be monitored by a healthcare professional.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember if it is not too close to your next dose. Otherwise, skip it and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure all stomach problems.
    Fact: It only relieves symptoms of indigestion and gas; it does not treat underlying conditions.
  • Myth: It is safe to take indefinitely without doctor's advice.
    Fact: Long-term use should be monitored by a doctor.
  • Myth: It can be taken on an empty stomach.
    Fact: It works best when taken with meals.

🔄 Alternative Options

Generic Alternatives

  • Pancreatin + Simethicone tablets from other manufacturers

Brand Alternatives

  • Dizec Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Pancreatin 175mg + Simethicone 25mg","use":"Indigestion, bloating, gas"},{"medicine":"Simethicone alone","composition":"Simethicone 40mg","use":"Gas and bloating only"},{"medicine":"Pancreatin alone","composition":"Pancreatin 175mg","use":"Pancreatic insufficiency"}]

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