Dyzerax Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain
- Difficulty breathing or swelling of face, lips, or throat
- Blood in stool or vomit
- Persistent diarrhea or constipation
- Signs of allergic reaction such as rash, itching, or hives
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is evanzyme 192mg/25mg/40mg tablet used for?
This medicine is a pancreatic enzyme and bile constituent combination used to treat pancreatic exocrine insufficiency. It helps digest food by replacing missing enzymes and bile, improving absorption of fats, proteins, and carbohydrates. It is taken with meals and should only be used under medical supervision.
- Generic Name: Pancreatin (192mg) + Bile constituents (25mg)
- Manufacturer: Evax Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 evanzyme 192mg/25mg/40mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैन्क्रियाटिक एंजाइम और बाइल घटकों का संयोजन है, जिसका उपयोग पैन्क्रियाज से अपर्याप्त पाचक एंजाइम का उत्पादन होने पर किया जाता है। यह भोजन के पाचन में मदद करती है, विशेष रूप से वसा, प्रोटीन और कार्बोहाइड्रेट के पाचन में। यह दवा आमतौर पर भोजन के साथ ली जाती है। यह पैन्क्रियाटिक अपर्याप्तता, क्रोनिक पैन्क्रियाटाइटिस, सिस्टिक फाइब्रोसिस और पैन्क्रियाज सर्जरी के बाद उपयोग की जाती है। इसका उपयोग डॉक्टर की सलाह के बिना न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में गैस, दस्त, कब्ज और पेट में असुविधा शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी एलर्जी जैसे दाने, खुजली या सूजन हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर पेट दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। डॉक्टर द्वारा बताई गई खुराक से अधिक न लें। यदि आपको सूअर के मांस से एलर्जी है, पैन्क्रियाटाइटिस है, या आंतों में रुकावट है, तो डॉक्टर को बताएं। दवा को बच्चों से दूर रखें। सूखी और ठंडी जगह पर स्टोर करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। अन्य दवाओं के साथ लेने से पहले डॉक्टर से पूछें।
💊 evanzyme 192mg/25mg/40mg tablet Uses & Benefits
[{"condition":"Pancreatic exocrine insufficiency","description":"This medicine replaces missing pancreatic enzymes to improve digestion and absorption of fats, proteins, and carbohydrates in people with chronic pancreatitis, cystic fibrosis, or after pancreatic surgery.","evidence":"Well-established"},{"condition":"Steatorrhea","description":"Helps reduce fatty stools and improve fat absorption in conditions where bile or pancreatic enzyme production is inadequate.","evidence":"Well-established"},{"condition":"Chronic pancreatitis","description":"Used as enzyme replacement therapy to manage maldigestion and malabsorption associated with chronic pancreatitis.","evidence":"Well-established"},{"condition":"Post-pancreatectomy","description":"Supports digestion after surgical removal of part or all of the pancreas.","evidence":"Well-established"},{"condition":"Cystic fibrosis","description":"Used in patients with cystic fibrosis who have pancreatic insufficiency to improve nutrient absorption.","evidence":"Well-established"},{"condition":"Biliary dyskinesia","description":"May be used to supplement bile constituents in certain gallbladder or bile duct disorders, though evidence is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Functional dyspepsia","description":"Sometimes prescribed off-label to aid digestion in people with unexplained indigestion, but evidence is not strong.","evidence":"Limited"},{"condition":"Irritable bowel syndrome","description":"Occasionally used off-label for bloating and gas, but not routinely recommended.","evidence":"Limited"}]
Primary treatment for: Pancreatic exocrine insufficiency
Also treats: Chronic pancreatitis, Cystic fibrosis, Steatorrhea, Post-pancreatectomy
📋 Drug Information
| Generic Name(s) | Pancreatin (192mg) + Bile constituents (25mg) |
| Brand Name | evanzyme 192mg/25mg/40mg tablet |
| Manufacturer | Evax Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by supplying exogenous pancreatic enzymes and bile constituents to the gastrointestinal tract. Pancreatin contains lipase, amylase, and protease, which break down fats, carbohydrates, and proteins respectively. Bile constituents help emulsify dietary fats into smaller droplets, increasing the surface area for lipase to act. Together, they mimic the natural digestive process, improving the breakdown and absorption of nutrients in people with pancreatic or biliary insufficiency.
Mechanism Steps
💡 How to Take evanzyme 192mg/25mg/40mg tablet
Strength: Pancreatin 192 mg + Bile constituents 25 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one to two tablets taken with each meal, but the exact dose depends on the severity of pancreatic insufficiency and the fat content of your diet. Your doctor will determine the right dose for you based on your condition, age, weight, and kidney and liver function. Do not adjust the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on kidney and liver function. Consult your doctor for personalized dosing. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Consult your doctor. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed the amount prescribed by your doctor. Typically, doses are adjusted based on the fat content of meals and clinical response. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of evanzyme 192mg/25mg/40mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Acarbose | Major | |
| Iron supplements | Major | |
| Antacids | Moderate | |
| Proton pump inhibitors | Moderate | |
| Folic acid | Minor |
🚨 Major Interactions
- Acarbose
- Iron supplements
⚡ Moderate Interactions
- Antacids
- Proton pump inhibitors
🍷 Alcohol Interaction
Alcohol may worsen pancreatitis and reduce the effectiveness of this medicine. It is advisable to avoid alcohol while taking this medicine, especially if you have a history of pancreatitis or liver disease.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to pork or any component of the medicine","Acute pancreatitis","Complete bowel obstruction","Acute exacerbation of chronic pancreatitis"]
⚠️ Warnings & Precautions
["Do not use if you have a history of allergy to pork products.","Use with caution in patients with gout or kidney stones due to purine content.","High doses may cause fibrosing colonopathy, especially in children with cystic fibrosis.","Do not exceed the recommended dose.","Consult your doctor before use if you are pregnant or breastfeeding.","Inform your doctor if you have liver or kidney disease.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine is unlikely to cause serious harm because it acts locally in the gut. However, very high doses may cause nausea, diarrhea, or abdominal pain. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it with your next meal if it is almost time. Otherwise, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine with meals or snacks as directed by your doctor. Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor advises otherwise. Do not exceed the prescribed dose. If you have a history of allergy to pork, pancreatitis, or bowel obstruction, inform your doctor before taking this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Inform your doctor about all other medicines you are taking, especially antacids, iron supplements, and diabetes medicines, as they may interact. Do not use this medicine for conditions other than those prescribed. If you miss a dose, take it with your next meal if it is almost time, otherwise skip it and continue with your regular schedule. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed after pancreatic or gallbladder surgery to aid digestion. Follow your doctor's instructions carefully.
🦷 Dental Procedures
No specific precautions are needed for dental procedures. However, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience abdominal pain or discomfort, avoid strenuous activities and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or discomfort, avoid these activities until you feel better.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your condition improves, your doctor may adjust or stop the dose.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when taken as prescribed. However, high doses may increase the risk of fibrosing colonopathy, especially in children with cystic fibrosis. Regular monitoring of nutritional status and stool patterns is recommended. Consult your doctor for periodic reviews.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating low-fat, easily digestible meals can complement medicine.
Evidence: Well-establishedMay help if deficiencies are present.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before any vaccination if you have a chronic illness.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it with meals as usual. Check customs regulations for carrying prescription medicines. Always carry enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes after taking it with food. You may notice improvement in digestion and stool consistency within a few days.
A: No, this medicine should always be taken with meals to be effective.
A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed.
🤔 Common Patient Concerns
🔄 Substitutes for evanzyme 192mg/25mg/40mg tablet
View AllAlternative brands with exact same active ingredient:
-
rizyme 192mg/25mg/40mg tabletMerril Pharma Pvt Ltd ₹56.25 36.8% CHEAPER
-
dyzerax tabletRax Health Care Pvt Ltd ₹70.00 21.4% CHEAPER
-
enzoset pb 192mg/25mg/40mg tabletSargas Life Sciences Pvt Ltd ₹84.38 5.3% CHEAPER
-
weldenz 192mg/25mg/40mg tabletWelgenic Pharma ₹84.38 5.3% CHEAPER
-
enzygut forte 192mg/25mg/40mg tabletTas Med India Pvt Ltd ₹87.66 1.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without food.
Fact: This medicine should be taken with meals to be effective. - Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller; it aids digestion. - Myth: This medicine can be used for any stomach problem.
Fact: This medicine is specifically for pancreatic enzyme insufficiency.
🔄 Alternative Options
Generic Alternatives
- Pancreatin + Bile constituents tablets
Brand Alternatives
- Creon
- Pancreaze
- Zenpep