e ova tablet - Enclomiphene (NA) medicine

E Ova Tablet (Enclomiphene): Comprehensive Medicine Guide

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🏭 Koye Pharmaceuticals Pvt ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not recommended in pregnancy. May cause fetal harm. Contraindicated in women who are or may become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden vision changes or blurred vision
  • Severe headache with nausea or vomiting
  • Chest pain or difficulty breathing
  • Swelling, pain, or redness in the legs
  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain
  • Signs of allergic reaction such as rash, itching, or swelling of face

If experiencing severe symptoms, call emergency services immediately.

What is e ova tablet used for?

This medicine contains enclomiphene, a selective estrogen receptor modulator used to treat low testosterone in men by stimulating natural hormone production.

  • Generic Name: Enclomiphene (NA)
  • Manufacturer: Koye Pharmaceuticals Pvt ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 e ova tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मुख्य रूप से पुरुषों में टेस्टोस्टेरोन की कमी (हाइपोगोनाडिज्म) के इलाज के लिए उपयोग की जाती है। यह शरीर में प्राकृतिक रूप से टेस्टोस्टेरोन का उत्पादन बढ़ाने में मदद करती है। इसके अलावा, कुछ मामलों में पुरुष बांझपन के इलाज में भी इसका उपयोग किया जा सकता है। यह दवा डॉक्टर के परामर्श के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, गर्म चमक, मूड में बदलाव और थकान शामिल हो सकते हैं। कुछ पुरुषों में स्तन में कोमलता या वृद्धि, मुँहासे, या यौन इच्छा में बदलाव भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दृष्टि में बदलाव, गंभीर सिरदर्द, सीने में दर्द, या पैरों में सूजन होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल योग्य डॉक्टर की देखरेख में ही लें। इस दवा को दूसरों के साथ साझा न करें। इलाज के दौरान नियमित रूप से टेस्टोस्टेरोन स्तर, लीवर फंक्शन और अन्य पैरामीटर की जांच करवाएं। शराब का सेवन न करें क्योंकि इससे दुष्प्रभाव बढ़ सकते हैं। यदि आपको दृष्टि में कोई बदलाव दिखे तो तुरंत दवा बंद करें और डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 e ova tablet Uses & Benefits

[{"condition":"Secondary hypogonadism in men","description":"This medicine is used to stimulate endogenous testosterone production in men with low testosterone due to inadequate pituitary signaling.","evidence":"Well-established"},{"condition":"Male infertility","description":"May be used to improve sperm count and motility in certain cases of male factor infertility.","evidence":"Moderate"},{"condition":"Delayed puberty in boys","description":"Occasionally used to induce puberty in adolescent boys with delayed onset.","evidence":"Limited"}]

Off-label uses: [{"condition":"Testosterone replacement alternative","description":"Sometimes used off-label as an alternative to testosterone therapy to maintain fertility.","evidence":"Limited"},{"condition":"Anabolic steroid-induced hypogonadism","description":"May be used to restore natural testosterone production after anabolic steroid use.","evidence":"Limited"}]

Primary treatment for: Secondary hypogonadism in men

Also treats: Male infertility, Delayed puberty

📋 Drug Information

Generic Name(s)Enclomiphene (NA)
Brand Namee ova tablet
ManufacturerKoye Pharmaceuticals Pvt ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassPartial estrogen agonist
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent levels.
2
Regular blood tests are essential to monitor testosterone and liver function.
3
Report any vision changes immediately, as this may require stopping the medicine.
4
Avoid alcohol to reduce liver strain and potential side effects.
5
Do not use this medicine if you are pregnant or planning to become pregnant.
6
Inform your doctor about all other medications you are taking to avoid interactions.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Low testosterone symptoms
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information.
DistributionNot established from the available information.
Protein BindingNot established from the available information.
MetabolismNot established from the available information.
Half-LifeNot established from the available information.
ExcretionNot established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionNot established from the available information.
Peak Plasma TimeNot established from the available information.
Duration of ActionNot established from the available information.

How It Works

Enclomiphene is a selective estrogen receptor modulator (SERM) that acts as an antagonist at estrogen receptors in the hypothalamus and pituitary gland. By blocking estrogen's negative feedback, it increases the secretion of gonadotropin-releasing hormone (GnRH), which leads to increased release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. Elevated LH and FSH then stimulate the testes to produce more testosterone and sperm.

Mechanism Steps

1
Estrogen receptor blockade: Enclomiphene binds to estrogen receptors in the hypothalamus and pituitary, preventing estrogen from exerting its negative feedback.
2
Increased GnRH secretion: With estrogen feedback blocked, the hypothalamus increases its release of gonadotropin-releasing hormone (GnRH).
3
Pituitary stimulation: GnRH stimulates the pituitary gland to secrete more luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
4
Testicular response: LH acts on Leydig cells to increase testosterone production, while FSH supports spermatogenesis in Sertoli cells.

💡 How to Take e ova tablet

Strength: Tablet, strength not specified.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food, but be consistent.
4Do not crush, chew, or break the tablet.
5If you miss a dose, follow the missed dose instructions.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe typical adult dose of this medicine is individualized by a qualified clinician based on the indication, patient's age, weight, and clinical response. It is usually taken once daily, with or without food. Dose adjustments may be necessary based on testosterone levels and side effects. Do not self-medicate; follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustments based on renal and hepatic function. Consult a healthcare provider.
Renal ImpairmentNot established from the available information. Use with caution in patients with renal impairment.
Hepatic ImpairmentNot established from the available information. Use with caution in patients with hepatic impairment.
Maximum Daily DoseNot established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Consistency is key; food does not significantly affect absorption.
Grapefruit
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of e ova tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if severe.
Hot flashes (Common (5-10%))
Usually temporary. Discuss with doctor if bothersome.
Mood swings (Common (5-10%))
Monitor mood changes. Consult doctor if significant.
Fatigue (Common (5-10%))
Ensure adequate rest. Consult doctor if persistent.

🚨 Serious Side Effects

Visual disturbances (Rare (<0.1%))
Stop medicine and seek immediate medical attention.
Liver enzyme elevation (Rare (<0.1%))
Regular monitoring required. Report jaundice or abdominal pain.
Blood clots (Rare (<0.1%))
Seek emergency care if chest pain, leg swelling, or shortness of breath occurs.

⚠️ Rare Side Effects

Gynecomastia
Consult doctor if breast tenderness or enlargement occurs.
Acne
Usually temporary. Consult dermatologist if severe.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ketoconazole Moderate
Rifampin Moderate
Antacids Minor

🚨 Major Interactions

  • Anticoagulants (e.g., warfarin)
  • Hormonal contraceptives

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., rifampin)

🍷 Alcohol Interaction

Alcohol may worsen liver side effects and increase dizziness or mood changes. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to enclomiphene or any component","Pregnancy or suspected pregnancy","Women of childbearing potential not using contraception","Uncontrolled prostate cancer","Severe liver disease"]

⚠️ Warnings & Precautions

["May cause visual disturbances; stop use and consult doctor if vision changes occur.","Regular monitoring of liver function is recommended.","May increase risk of blood clots; use with caution in patients with history of thromboembolism.","Not for use in women who are breastfeeding.","Avoid in patients with uncontrolled hormone-sensitive cancers."]

🤱 Lactation Safety

Not established from the available information. Consult a healthcare provider before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, visual disturbances, and dizziness. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

This medicine should only be taken under the supervision of a qualified healthcare provider. Do not share this medicine with others, even if they have similar symptoms. Before starting treatment, inform your doctor about all your medical conditions, especially liver disease, kidney disease, or a history of blood clots. Regular blood tests to monitor testosterone levels, liver function, and other parameters are essential during treatment. Avoid alcohol consumption as it may worsen side effects and affect liver health. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Never double the dose. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children. If you experience any vision changes, stop the medicine and contact your doctor immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to side effects. Dose adjustments may be necessary based on renal and hepatic function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated in women who are pregnant or planning to become pregnant. Men taking this medicine should discuss fertility plans with their doctor.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery due to potential risk of blood clots.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. No specific precautions are known, but maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to support hormone balance.
🥗
Exercise regularly to improve testosterone levels naturally.
😴
Get adequate sleep to support hormone production.
💧
Manage stress through relaxation techniques.
🧘
Avoid excessive alcohol and smoking.

🏋️ Exercise Considerations

No specific exercise restrictions are known, but if you experience dizziness or visual changes, avoid strenuous activities until you consult your doctor.

🥗 Diet Recommendations

Include zinc-rich foods like nuts and seeds.
Eat a balanced diet with plenty of fruits and vegetables.
Stay hydrated.
Limit processed foods and sugary drinks.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or visual changes in some individuals. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their daily activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like vision changes or severe allergic reactions, stop immediately and seek medical help.

📅 Long-Term Use Effects

Long-term use of this medicine requires regular monitoring of testosterone levels, liver function, and visual acuity. Some patients may experience persistent side effects like mood changes or gynecomastia. It is important to have periodic evaluations to ensure safety and efficacy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Testosterone replacement therapy

Directly increases testosterone levels but may suppress fertility.

Evidence: Well-established
Lifestyle modifications

Diet, exercise, and stress reduction can naturally boost testosterone.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. Consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule gradually as advised by your doctor. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with low testosterone and fatigue
He was prescribed this medicine by his endocrinologist. After 6 weeks, his energy levels improved and blood tests showed increased testosterone. He experienced mild headache initially, which resolved. He emphasizes the importance of regular follow-ups.
💡 Lesson: Consistent use and monitoring lead to improved outcomes.
👤 A 42-year-old man with male infertility
He and his partner were trying to conceive for 2 years. After taking this medicine for 3 months, his sperm count improved significantly. He advises others to be patient and follow the doctor's advice.
💡 Lesson: This medicine can improve fertility parameters when taken as prescribed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvements in testosterone levels may be seen within 2-4 weeks, but full effects may take 3 months. Follow your doctor's monitoring schedule.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food, but be consistent.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but skip if it's almost time for the next dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for e ova tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Enclomiphene is a steroid.
    Fact: Enclomiphene is not a steroid; it is a selective estrogen receptor modulator that stimulates natural testosterone production.
  • Myth: Enclomiphene is only for bodybuilders.
    Fact: It is a prescription medicine for medical conditions like hypogonadism, not for performance enhancement.

📊 Comparison with Similar Medicines

[{"medicine":"Enclomiphene","class":"SERM","main_use":"Hypogonadism","route":"Oral"},{"medicine":"Clomiphene","class":"SERM","main_use":"Infertility","route":"Oral"},{"medicine":"Testosterone","class":"Androgen","main_use":"Hypogonadism","route":"Various"}]

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