dydro 10mg tablet - Dydrogesterone (10mg) medicine

dydro 10mg tablet

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๐Ÿญ Integrace Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Sep 6, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Sep 06, 2026

What is dydro 10mg tablet used for?

Celogest 100mg Capsule (Dydrogesterone) is used to treat GYNAECOLOGICAL. It contains Dydrogesterone (10mg), which Selective progestogen that binds to progesterone receptors, inducing secretory t. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Dydrogesterone
  • Manufacturer: Integrace Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š dydro 10mg tablet Uses & Benefits

Progesterone supplementation in assisted reproductive technology; treatment of threatened and recurrent miscarriage; dysmenorrhea; endometriosis; secondary amenorrhea; dysfunctional uterine bleeding.

Off-label uses: Premenstrual syndrome; luteal phase support in IVF; hormone replacement therapy.

๐Ÿ“‹ Drug Information

Generic Name(s)Dydrogesterone
Brand NameCelogest 100mg Capsule
ManufacturerIntegrace Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassProgestins (First generation)
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; peak plasma concentration reached within 2-5 hours.
DistributionDistributed widely; crosses placenta; enters breast milk.
Protein Binding>90% bound to albumin and sex hormone-binding globulin.
MetabolismExtensively metabolized in the liver via reduction and conjugation; major metabolite is 20ฮฑ-dihydrodydrogesterone.
Half-Life5-7 hours for parent drug; 14-17 hours for active metabolite.
ExcretionPrimarily in urine (as metabolites); small amount in feces.
Bioavailability28% (oral) due to first-pass metabolism.
Onset of ActionWithin 24-48 hours for endometrial transformation.
Peak Plasma Time2-5 hours.
Duration of ActionApproximately 24 hours.

How It Works

Selective progestogen that binds to progesterone receptors, inducing secretory transformation of the endometrium and maintaining pregnancy.

Mechanism Steps

1Binds to progesterone receptors in target tissues.
2Induces conformational change and receptor dimerization.
3Translocation to nucleus and binding to progesterone response elements.

๐Ÿ’ก How to Take dydro 10mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of dydro 10mg tablet

โœ… Common Side Effects

  • Headache
  • Nausea
  • Abdominal pain
  • Breast tenderness
  • Dizziness
  • Vaginal spotting

๐Ÿšจ Serious Side Effects

  • Thromboembolism
  • Severe allergic reaction
  • Liver dysfunction
  • Depression

โš ๏ธ Rare Side Effects

  • Cholestatic jaundice
  • Anaphylaxis
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Rifampin Major Decreased dydrogesterone efficacy due to CYP3A4 induction.
Ketoconazole Major Increased dydrogesterone exposure; risk of side effects.
Warfarin Moderate Possible altered anticoagulant effect; monitor INR.
Corticosteroids Moderate Potential increased corticosteroid effects.
Grapefruit juice Minor May slightly increase dydrogesterone levels.

๐Ÿšจ Major Interactions

  • CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

โšก Moderate Interactions

  • Warfarin
  • Corticosteroids
  • Antidiabetic agents

โ„น๏ธ Minor Interactions

  • Grapefruit juice
  • St. John's Wort

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

No known interaction; moderate consumption unlikely to affect efficacy.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to dydrogesterone; known or suspected progestogen-dependent tumors; undiagnosed vaginal bleeding; severe liver disease.

๐Ÿ“Š Monitoring Parameters

Pregnancy test; liver function tests; endometrial biopsy if indicated; bleeding patterns.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

No specific antidote; symptomatic and supportive care; gastric lavage if recent ingestion.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Sep 06, 2026

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๐Ÿ”„ Substitutes for dydro 10mg tablet

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Alternative brands with exact same active ingredient (Dydrogesterone (10mg)):

Medical Note: Always consult your doctor before switching medications.

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