alesa gel allopathy (Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India
alesa gel allopathy (Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by Integrace Pvt Ltd. Contains Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w).

alesa gel - Uses, Price, Side Effects & Substitutes

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🏭 Integrace Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 22, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is alesa gel used for?

Aclind BP 2.5% Gel (Benzoyl Peroxide + Clindamycin) is used to treat Acne vulgaris (inflammatory and non-inflammatory lesions). It contains Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w), which Benzoyl peroxide: oxidizing agent with bactericidal activity against Propionibac. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Benzoyl Peroxide + Clindamycin
  • Manufacturer: Integrace Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: C

🇮🇳 alesa gel के बारे में संक्षिप्त जानकारी (Hindi Summary)

alesa gel का उपयोग मुख्य रूप से derma और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Benzoyl Peroxide + Clindamycin
Brand NameAclind BP 2.5% Gel
ManufacturerIntegrace Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassTopical Antibiotic + Keratolytic
Route of AdministrationTopical
StorageStore at 20-25°C (68-77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption; primarily local action on skin
DistributionLimited to skin layers; negligible systemic distribution
Protein BindingClindamycin: ~94% bound to plasma proteins; Benzoyl Peroxide: not applicable
MetabolismClindamycin: Hepatic via CYP3A4; Benzoyl Peroxide: degraded to benzoic acid on skin
Half-LifeClindamycin: ~2.4 hours (systemic); Benzoyl Peroxide: not applicable
ExcretionClindamycin: Renal and biliary; Benzoyl Peroxide: excreted as benzoic acid in urine
BioavailabilityMinimal systemic bioavailability due to topical application
Onset of ActionWithin 2 weeks of regular use
Peak Plasma TimeNot applicable (topical)
Duration of ActionSustained with regular application

Pharmacodynamics

Mechanism of ActionBenzoyl peroxide: oxidizing agent with bactericidal activity against Propionibacterium acnes and keratolytic effect; Clindamycin: inhibits bacterial protein synthesis by binding to 50S ribosomal subunit
Target ReceptorBacterial 50S ribosomal subunit (Clindamycin); microbial cell components (Benzoyl peroxide)
Pharmacodynamic EffectsReduction of P. acnes count, decreased inflammation, normalization of follicular keratinization

💡 How and when to take alesa gel?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 20-25°C (68-77°F); protect from light and moisture

⚙️ How alesa gel Works

Benzoyl peroxide: oxidizing agent with bactericidal activity against Propionibacterium acnes and keratolytic effect; Clindamycin: inhibits bacterial protein synthesis by binding to 50S ribosomal subunit

1 Benzoyl peroxide releases free oxygen radicals that oxidize bacterial proteins, killing P. acnes
⬇️
2 Benzoyl peroxide also has keratolytic effect, reducing follicular hyperkeratinization
⬇️
3 Clindamycin binds to 50S ribosomal subunit of bacteria, inhibiting peptide bond formation and protein synthesis
⬇️
4 Reduction of bacterial population decreases inflammatory mediators and comedone formation

💊 alesa gel Uses in Hindi (Ke Fayde), Benefits & Indications

Acne vulgaris (inflammatory and non-inflammatory lesions)

Off-label uses: Rosacea, Folliculitis, Hidradenitis suppurativa

⚠️ What are the side effects of alesa gel?

✅ Common Side Effects

  • Skin dryness
  • Peeling
  • Erythema
  • Burning sensation
  • Pruritus

🚨 Serious Side Effects

  • Severe allergic reaction
  • Pseudomembranous colitis (rare)
  • Stevens-Johnson syndrome (very rare)

⚠️ Rare Side Effects

  • Contact dermatitis
  • Photosensitivity
  • Urticaria

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Erythromycin Major Antagonism of antibacterial effect
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Warfarin Moderate Possible increased INR
Oral contraceptives Moderate Reduced contraceptive efficacy (rare)
Topical retinoids Minor Increased skin irritation
Sunscreens Minor Possible reduced efficacy of sunscreen

🚨 Major Interactions

  • Erythromycin
  • Other topical antibiotics
  • Neuromuscular blocking agents

⚡ Moderate Interactions

  • Warfarin
  • Oral contraceptives

ℹ️ Minor Interactions

  • Topical retinoids
  • Sunscreens

🍽️ Food Interactions

None known

🍷 Alcohol Interaction

No known interaction

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to benzoyl peroxide, clindamycin, or any component; history of enteritis or antibiotic-associated colitis

📊 Monitoring Parameters

Skin irritation, dryness, peeling; clinical improvement of acne lesions

🤱 Lactation Safety

Use with caution; limited data on excretion in breast milk

💊 Overdose Management

Topical overdose unlikely; if excessive application, wash skin with mild soap and water; symptomatic treatment

⏰ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose; do not double dose

🛑 Myths vs. Facts about alesa gel

  • Myth: Generic substitutes of alesa gel are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Benzoyl Peroxide (5% w/w) + Clindamycin (1% w/w)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of alesa gel can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

💬 Real Patient Experiences (Astitva)

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