ducaine tablet - Oxetacaine (5mg) + Magaldrate (400mg) medicine

ducaine tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ SKN Organics ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 3, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 03, 2026

What is ducaine tablet used for?

Ducaine (Oxetacaine + Magaldrate) is used to treat GASTRO INTESTINAL. It contains Oxetacaine (5mg) + Magaldrate (400mg), which Magaldrate neutralizes gastric acid; oxetacaine provides local anesthetic effect. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Oxetacaine + Magaldrate
  • Manufacturer: SKN Organics
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š ducaine tablet Uses & Benefits

Gastric ulcers, duodenal ulcers, hyperacidity, heartburn.

Off-label uses: Gastroesophageal reflux disease (GERD) off-label.

๐Ÿ“‹ Drug Information

Generic Name(s)Oxetacaine + Magaldrate
Brand NameDucaine
ManufacturerSKN Organics
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntacid + Local Anesthetic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMagaldrate is poorly absorbed; oxetacaine is minimally absorbed from GI tract.
DistributionMinimal systemic distribution due to low absorption.
Protein BindingNot applicable due to minimal absorption.
MetabolismNot metabolized significantly.
Half-LifeNot applicable.
ExcretionPrimarily fecal.
BioavailabilityNegligible systemic bioavailability.
Onset of ActionRapid (within minutes) for antacid effect.
Peak Plasma TimeNot applicable.
Duration of Action1-2 hours.

How It Works

Magaldrate neutralizes gastric acid; oxetacaine provides local anesthetic effect on gastric mucosa.

Mechanism Steps

1Magaldrate reacts with gastric acid to form aluminum and magnesium salts, reducing acidity.
2Oxetacaine stabilizes neuronal membranes and inhibits sodium influx, providing local anesthesia.
3Combined effect reduces pain and discomfort from gastric irritation.

๐Ÿ’ก How to Take ducaine tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of ducaine tablet

โœ… Common Side Effects

  • Constipation
  • Diarrhea
  • Nausea

๐Ÿšจ Serious Side Effects

  • Hypophosphatemia
  • Magnesium toxicity (rare)

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Metabolic alkalosis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Tetracyclines Major Reduced absorption of tetracyclines
Fluoroquinolones Major Reduced absorption of fluoroquinolones
Iron supplements Major Reduced iron absorption
Digoxin Moderate Possible reduced digoxin absorption
Indomethacin Moderate Possible reduced indomethacin absorption
Corticosteroids Moderate Possible reduced corticosteroid absorption
Anticholinergics Minor Possible additive anticholinergic effects
Benzodiazepines Minor Possible reduced absorption of benzodiazepines

๐Ÿšจ Major Interactions

  • Tetracyclines
  • Fluoroquinolones
  • Iron supplements

โšก Moderate Interactions

  • Digoxin
  • Indomethacin
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Anticholinergics
  • Benzodiazepines

๐Ÿฝ๏ธ Food Interactions

Milk and dairy products may reduce efficacy

๐Ÿท Alcohol Interaction

No significant interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe renal impairment.

๐Ÿ“Š Monitoring Parameters

Gastric pH, symptom relief, renal function in long-term use.

๐Ÿคฑ Lactation Safety

Likely safe; minimal systemic absorption.

๐Ÿ’Š Overdose Management

Gastric lavage, supportive measures; monitor electrolytes.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jul 03, 2026

๐Ÿ”— View Profile

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