Biflozin 5 Tablet: A Complete Guide to Uses, Benefits, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe nausea, vomiting, or abdominal pain
- Deep rapid breathing or difficulty breathing
- Fruity-smelling breath
- Severe pain, redness, or swelling in the genital or perineal area with fever
- Decreased urine output or swelling in the legs
- Dizziness, lightheadedness, or fainting
- Signs of severe allergic reaction such as swelling of face, lips, or throat
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is dpo 5mg tablet used for?
This medicine contains dapagliflozin 5 mg, an SGLT2 inhibitor used to treat type 2 diabetes, heart failure, and chronic kidney disease. It works by helping the kidneys remove excess glucose through urine. It is taken orally once daily, with or without food, as prescribed by a doctor.
- Generic Name: Dapagliflozin (5mg)
- Manufacturer: RPG Life Sciences Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dpo 5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डैपाग्लिफ्लोज़िन 5 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग टाइप 2 डायबिटीज में ब्लड शुगर को नियंत्रित करने के लिए किया जाता है। यह दवा किडनी में ग्लूकोज के पुनर्अवशोषण को कम करके अतिरिक्त शर्करा को पेशाब के माध्यम से बाहर निकालने में मदद करती है। इसके अलावा, यह हृदय विफलता और क्रोनिक किडनी रोग वाले मरीजों में अस्पताल में भर्ती होने का खतरा कम करने और किडनी की कार्यक्षमता को बनाए रखने में भी सहायक है। यह दवा डॉक्टर के परामर्श के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जननांगों में फंगल संक्रमण, मूत्र मार्ग में संक्रमण और पेशाब की मात्रा बढ़ना शामिल हैं। कुछ लोगों को चक्कर आना, निम्न रक्तचाप या हल्की निर्जलीकरण का अनुभव हो सकता है। दुर्लभ मामलों में डायबिटिक कीटोएसिडोसिस हो सकता है, जिसके लक्षण जैसे मतली, उल्टी, पेट दर्द, सांस लेने में कठिनाई हो सकते हैं। अगर आपको जननांग क्षेत्र में गंभीर दर्द, लालिमा या सूजन के साथ बुखार हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में एक बार सुबह के समय, भोजन के साथ या बिना। पर्याप्त पानी पिएं ताकि शरीर में पानी की कमी न हो। जननांगों की सफाई का ध्यान रखें ताकि संक्रमण से बचाव हो सके। अपने ब्लड शुगर की नियमित जांच करते रहें। अगर आपको मतली, उल्टी, पेट दर्द या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर को बताएं। शराब का सेवन न करें क्योंकि इससे निर्जलीकरण और लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। सर्जरी या डेंटल प्रक्रिया से पहले अपने डॉक्टर को इस दवा के बारे में जरूर बताएं।
💊 dpo 5mg tablet Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"This medicine helps lower blood sugar levels in adults with type 2 diabetes by increasing glucose excretion through urine.","evidence":"Well-established"},{"condition":"Heart failure with reduced ejection fraction","description":"This medicine reduces the risk of cardiovascular death and hospitalization for heart failure in adults with symptomatic chronic heart failure.","evidence":"Well-established"},{"condition":"Chronic kidney disease","description":"This medicine slows the decline of kidney function and reduces the risk of end-stage kidney disease in adults with chronic kidney disease, with or without type 2 diabetes.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Weight management in obesity","description":"Sometimes prescribed off-label to support modest weight loss in people with obesity and type 2 diabetes, but it is not approved for weight loss alone.","evidence":"Limited"},{"condition":"Non-alcoholic fatty liver disease","description":"Preliminary studies suggest possible benefit in reducing liver fat, but this is not an approved indication.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Heart failure with reduced ejection fraction, Chronic kidney disease
📋 Drug Information
| Generic Name(s) | Dapagliflozin (5mg) |
| Brand Name | dpo 5mg tablet |
| Manufacturer | RPG Life Sciences Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | SGLT2 inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, and protect them from moisture and light. Do not refrigerate unless specified by the manufacturer. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. Guidelines from various professional bodies recommend SGLT2 inhibitors like dapagliflozin as second-line or add-on therapy for type 2 diabetes and as preferred agents in patients with heart failure or chronic kidney disease. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research (ICMR) guidelines for diabetes management may include SGLT2 inhibitors as part of a comprehensive treatment plan. Consult the latest ICMR guidelines for specific recommendations. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine selectively inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal tubules of the kidneys. By blocking this transporter, it reduces the reabsorption of filtered glucose and sodium, leading to increased urinary glucose excretion and mild osmotic diuresis. This effect lowers blood glucose levels independently of insulin secretion. The accompanying natriuresis and osmotic diuresis contribute to reductions in blood pressure and body weight. Additionally, this medicine may improve cardiac and renal outcomes through mechanisms that are not fully understood, possibly involving improved renal oxygenation, reduced inflammation, and favorable metabolic shifts.
Mechanism Steps
💡 How to Take dpo 5mg tablet
Strength: Immediate-release tablet containing 5 mg of dapagliflozin.
Dosage Information
| Adult Dosage | The usual recommended dose of this medicine for adults is 5 mg taken orally once daily, with or without food. The dose may be increased to 10 mg once daily if additional blood sugar control is needed and the medicine is well tolerated. For heart failure and chronic kidney disease, the recommended dose is 10 mg once daily, but your doctor may start with 5 mg. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, particularly regarding dehydration and low blood pressure. Dose selection should be cautious, and kidney function should be monitored regularly. No specific dose adjustment is recommended based solely on age, but individualization is important. |
| Renal Impairment | For patients with mild to moderate renal impairment (eGFR 45 to less than 90 mL/min/1.73 m2), no dose adjustment is needed. For patients with moderate renal impairment (eGFR 30 to less than 45 mL/min/1.73 m2), the dose may be limited to 5 mg once daily for glycemic control, but for heart failure and chronic kidney disease, 10 mg once daily may be used. This medicine is not recommended for patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2) or on dialysis. |
| Hepatic Impairment | No dose adjustment is recommended for patients with mild or moderate hepatic impairment. The use of this medicine in patients with severe hepatic impairment is not recommended due to limited data. |
| Maximum Daily Dose | 10 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dpo 5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | |
| Sulfonylureas | Major | |
| Furosemide | Major | |
| Hydrochlorothiazide | Major | |
| Lisinopril | Moderate | |
| Losartan | Moderate | |
| Ibuprofen | Moderate | |
| Naproxen | Moderate | |
| Rifampicin | Minor | |
| Digoxin | Minor |
🚨 Major Interactions
- Insulin or insulin secretagogues (e.g., sulfonylureas)
- Diuretics (e.g., furosemide, hydrochlorothiazide)
⚡ Moderate Interactions
- ACE inhibitors or angiotensin receptor blockers (ARBs)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
🍷 Alcohol Interaction
Alcohol may increase the risk of lactic acidosis and dehydration when taken with this medicine. It is advisable to limit or avoid alcohol consumption while on this medicine, especially if you have liver or kidney problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to dapagliflozin or any component of the formulation","Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment (eGFR less than 30 mL/min/1.73 m2) or on dialysis","Pregnancy (especially second and third trimesters)","Breastfeeding"]
⚠️ Warnings & Precautions
["Risk of diabetic ketoacidosis: This medicine can cause ketoacidosis even if blood sugar is not high. Seek medical help if you have nausea, vomiting, abdominal pain, or difficulty breathing.","Risk of genital mycotic infections: Maintain good hygiene and report symptoms such as itching, redness, or discharge.","Risk of urinary tract infections: Drink plenty of water and report symptoms such as burning sensation or frequent urination.","Risk of volume depletion and hypotension: This medicine can cause dehydration and low blood pressure. Monitor for dizziness and lightheadedness.","Risk of acute kidney injury: Kidney function should be monitored, especially in patients with existing kidney disease or those taking other kidney-affecting medicines.","Risk of hypoglycemia when used with insulin or sulfonylureas: Dose adjustment of these medicines may be needed.","Risk of necrotizing fasciitis of the perineum: A rare but serious condition. Seek immediate medical attention if you experience severe pain, redness, or swelling in the genital area with fever.","Not recommended for patients with type 1 diabetes or diabetic ketoacidosis.","Not recommended during pregnancy and breastfeeding."]
🤱 Lactation Safety
Not established from the available information. It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in a breastfed infant, breastfeeding is not recommended while taking this medicine. Consult your doctor for guidance.
💊 Overdose Management
In case of overdose, seek immediate medical attention. There is no specific antidote for this medicine. Treatment should be supportive and symptomatic. Monitor blood glucose, blood pressure, and kidney function. Hemodialysis may be considered in severe cases, but the effectiveness of dialysis in removing this medicine is not well established.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily in the morning, with or without food. Do not crush, chew, or split the tablet unless your doctor specifically tells you to do so. Drink plenty of water throughout the day to stay well hydrated, especially in hot weather or during physical activity. Maintain good genital hygiene to reduce the risk of fungal and urinary tract infections. Check your blood sugar levels regularly as advised by your healthcare provider. Inform your doctor immediately if you experience symptoms of ketoacidosis such as nausea, vomiting, stomach pain, tiredness, or difficulty breathing. Do not start or stop any other medicine without consulting your doctor, as some medicines can interact with this product. Avoid excessive alcohol consumption because it can increase the risk of lactic acidosis and dehydration. If you are scheduled for surgery or a dental procedure, tell your doctor that you are taking this medicine. Keep this medicine out of the reach of children and store it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to dehydration and low blood pressure while taking this medicine. Kidney function should be monitored regularly. The dose may need to be adjusted based on kidney function. Falls due to dizziness should be prevented.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative. Effective contraception should be used while taking this medicine. If you become pregnant while on this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily stopped before surgery due to the risk of ketoacidosis and dehydration. Inform your surgeon and anesthesiologist that you are taking this medicine. Your doctor will advise when to restart it after surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. There is no specific contraindication for dental procedures, but maintaining good oral hygiene is important, especially if you have diabetes. Your dentist may recommend monitoring blood sugar levels before and after the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine, but you should stay well hydrated to prevent dehydration and low blood pressure. If you experience dizziness or weakness during exercise, stop and rest. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness in some people, especially during the initial days of treatment. If you experience these symptoms, avoid driving or operating heavy machinery until you feel better. Otherwise, it should not significantly affect your daily work life. Maintain regular meals and hydration to minimize side effects.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as ketoacidosis, severe allergic reactions, or necrotizing fasciitis, seek immediate medical attention and your doctor will advise whether to stop the medicine. Your doctor may also stop the medicine if your kidney function declines significantly or if you become pregnant.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and well-tolerated. It may lead to sustained improvements in blood sugar control, reduced risk of heart failure hospitalization, and slowed progression of kidney disease. Regular monitoring of kidney function, blood sugar, and blood pressure is recommended. Some patients may experience persistent genital fungal infections or urinary tract infections, which may require treatment. Rarely, long-term use may be associated with vitamin B12 deficiency, so monitoring may be advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are essential for managing diabetes and can complement medicine.
Evidence: Well-establishedMetformin, sulfonylureas, DPP-4 inhibitors, and other SGLT2 inhibitors are alternatives.
Evidence: Well-establishedMay be needed if oral medicines are not enough to control blood sugar.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, people with diabetes should stay up to date with recommended vaccinations, including influenza and pneumococcal vaccines, as they are at higher risk of infections.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. Store it at room temperature and away from direct sunlight. If you are crossing time zones, continue taking your dose at the same time each day as much as possible. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within a few hours, but the full effect may take several days to weeks. Your doctor will monitor your progress.
A: Yes, it is often used in combination with other diabetes medicines such as metformin, sulfonylureas, or insulin. However, your doctor may need to adjust the doses to avoid low blood sugar.
A: Seek immediate medical help if you experience nausea, vomiting, abdominal pain, difficulty breathing, severe genital pain or swelling, or signs of an allergic reaction.
A: This medicine may actually protect the kidneys in people with chronic kidney disease. However, it can cause acute kidney injury in some situations, so regular monitoring is important.
🤔 Common Patient Concerns
🔄 Substitutes for dpo 5mg tablet
View AllAlternative brands with exact same active ingredient:
-
dgson 5 tabletUnison Pharmaceuticals Pvt Ltd ₹29.63 60.5% CHEAPER
-
dapazee 5 tabletZeelab Pharmacy Pvt Ltd ₹42.00 44% CHEAPER
-
dapagain 5mg tabletSystopic Laboratories Pvt Ltd ₹54.84 26.9% CHEAPER
-
switdapa 5mg tabletAkumentis Healthcare Ltd ₹55.31 26.3% CHEAPER
-
dapamax 5mg tabletShinto Organics (P) Limited ₹73.13 2.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a weight loss pill.
Fact: This medicine may cause modest weight loss as a side effect, but it is not approved for weight loss and should not be used for that purpose alone. - Myth: This medicine can be taken by anyone with diabetes.
Fact: This medicine is not suitable for people with type 1 diabetes or diabetic ketoacidosis. It is specifically approved for type 2 diabetes and certain heart and kidney conditions. - Myth: This medicine can be stopped once blood sugar is normal.
Fact: This medicine is a long-term treatment. Stopping it without medical advice can lead to worsening of blood sugar control and increased risk of complications. - Myth: This medicine causes kidney damage.
Fact: This medicine may actually protect the kidneys in people with chronic kidney disease. However, it can cause acute kidney injury in some situations, so monitoring is important.
🔄 Alternative Options
Generic Alternatives
- Dapagliflozin 5 mg tablet
Brand Alternatives
- Biflozin 5 Tablet