doxonimar tablet - Doxofylline (NA) medicine

Doxonimar Tablet: Complete Medicine Guide

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🏭 Emcee Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for asthma and COPD.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Rapid or irregular heartbeat
  • Seizures
  • Severe allergic reactions like swelling of face, lips, or throat
  • Difficulty breathing
  • Severe nausea or vomiting
  • Blood in vomit or stool

If experiencing severe symptoms, call emergency services immediately.

What is doxonimar tablet used for?

This medicine is a bronchodilator used to treat asthma and COPD. It works by relaxing the muscles in the airways to make breathing easier. It is usually taken 2-3 times daily with food.

  • Generic Name: Doxofylline (NA)
  • Manufacturer: Emcee Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 doxonimar tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डॉक्सोफाइलिन नामक सक्रिय तत्व से बनी है और अस्थमा तथा क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिजीज (सीओपीडी) के इलाज में उपयोग की जाती है। यह श्वास नलियों की मांसपेशियों को आराम देकर सांस लेने में आसानी प्रदान करती है। यह दवा सूजन को भी कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द और बेचैनी शामिल हैं। गंभीर दुष्प्रभाव जैसे तेज़ धड़कन, दौरे और एलर्जी प्रतिक्रियाएँ दुर्लभ हैं लेकिन तुरंत चिकित्सा की आवश्यकता होती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ निगलें, चबाएं नहीं। शराब का सेवन न करें। यदि आपको हृदय, यकृत, गुर्दे की बीमारी या पेप्टिक अल्सर है तो डॉक्टर को बताएं। दवा अचानक बंद न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 doxonimar tablet Uses & Benefits

[{"condition":"Asthma","description":"This medicine helps relieve bronchospasm and improves breathing in patients with asthma.","evidence":"Well-established"},{"condition":"Chronic Obstructive Pulmonary Disease (COPD)","description":"It reduces airway obstruction and improves lung function in patients with COPD, including chronic bronchitis and emphysema.","evidence":"Well-established"},{"condition":"Bronchospasm","description":"This medicine relaxes the smooth muscles of the airways, providing relief from bronchospasm.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Apnea of prematurity","description":"Sometimes used off-label in premature infants to stimulate breathing, but this is not a standard use and requires specialist supervision.","evidence":"Limited"}]

Primary treatment for: Asthma

Also treats: Chronic Obstructive Pulmonary Disease (COPD), Chronic Bronchitis, Emphysema

📋 Drug Information

Generic Name(s)Doxofylline (NA)
Brand Namedoxonimar tablet
ManufacturerEmcee Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassTheophylline & its derivatives
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual heartbeat or restlessness immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for this.
Likely Use
✅
Shortness of breath
This medicine helps relieve this symptom.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDoxofylline is rapidly absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 60-70%.
DistributionDoxofylline is widely distributed in the body, with a volume of distribution of about 1 L/kg. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 30% of doxofylline is bound to plasma proteins.
MetabolismDoxofylline is metabolized in the liver by cytochrome P450 enzymes, primarily CYP1A2 and CYP3A4.
Half-LifeThe elimination half-life of doxofylline is approximately 6-8 hours in healthy adults.
ExcretionDoxofylline and its metabolites are primarily excreted through the kidneys. About 80% of a dose is excreted in urine within 24 hours.
BioavailabilityThe oral bioavailability of doxofylline is about 60-70%.
Onset of ActionThe onset of action is usually within 30 minutes to 1 hour after oral administration.
Peak Plasma TimePeak plasma concentration is reached approximately 1-2 hours after oral administration.
Duration of ActionThe duration of action is about 6-8 hours, so it is usually taken 2-3 times daily.

How It Works

Doxofylline works by inhibiting the enzyme phosphodiesterase, which increases the levels of cyclic AMP in the airway smooth muscle cells. This leads to relaxation of the bronchial smooth muscles and widening of the airways. Additionally, it has anti-inflammatory effects by reducing the release of inflammatory mediators from mast cells and other cells. Unlike other methylxanthines, doxofylline has a better safety profile with fewer cardiac and central nervous system side effects.

Mechanism Steps

1
Inhibition of phosphodiesterase: This medicine inhibits the phosphodiesterase enzyme in airway smooth muscle cells.
2
Increase in cyclic AMP: Inhibition of phosphodiesterase leads to increased levels of cyclic AMP within the cells.
3
Relaxation of smooth muscles: Elevated cyclic AMP causes relaxation of the bronchial smooth muscles, resulting in bronchodilation.
4
Reduction of inflammation: This medicine also reduces the release of inflammatory mediators, contributing to its therapeutic effect.

💡 How to Take doxonimar tablet

Strength: This medicine is available as a tablet. The strength is not specified in the available information.

1Swallow the tablet whole with a glass of water.
2Take it with food to reduce stomach upset.
3Do not crush or chew the tablet.
4Take it at the same times each day.
5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 400 mg two to three times daily, but the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment due to reduced liver and kidney function. Consult your doctor.
Renal ImpairmentDose adjustment may be needed in patients with renal impairment. Consult your doctor.
Hepatic ImpairmentDose adjustment may be needed in patients with hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 1200 mg, but this must be confirmed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase restlessness and palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of doxonimar tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and avoid heavy meals. Consult doctor if severe.
Stomach pain (Common (5-10%))
Take with food or milk to reduce irritation.
Headache (Common (5-10%))
Rest and stay hydrated. Use over-the-counter pain relief if needed, but consult doctor first.
Restlessness (Common (5-10%))
Avoid caffeine and get adequate rest. Consult doctor if it interferes with daily activities.

🚨 Serious Side Effects

Rapid or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations or chest discomfort.
Seizures (Rare (<0.1%))
Call emergency services if seizures occur.
Severe allergic reactions (Rare (<0.1%))
Seek immediate medical help if you notice rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hyperglycemia
Monitor blood sugar if diabetic. Consult doctor if levels rise.
Hypokalemia
Report muscle weakness or cramps to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Erythromycin Major
Phenytoin Moderate
Rifampicin Moderate
Cimetidine Minor

🚨 Major Interactions

  • Ciprofloxacin
  • Erythromycin

⚡ Moderate Interactions

  • Phenytoin
  • Rifampicin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it may increase the risk of central nervous system side effects and gastrointestinal irritation.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to doxofylline or other methylxanthines","Severe cardiac arrhythmias","Active peptic ulcer","Severe liver disease","Children under 12 years of age"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease, hypertension, or arrhythmias.","Use with caution in patients with liver or kidney disease.","Avoid in patients with peptic ulcer.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not exceed the recommended dose."]

🤱 Lactation Safety

Doxofylline is excreted in breast milk. It is not known if it is safe for the baby. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, rapid heartbeat, seizures, and cardiac arrest. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush or chew the tablet; swallow it whole with a glass of water. Avoid consuming alcohol while taking this medicine as it may increase the risk of side effects. Inform your doctor if you have heart disease, liver disease, kidney disease, or peptic ulcer before starting this medicine. Do not stop taking this medicine suddenly without consulting your doctor, as it may worsen your symptoms. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be needed based on liver and kidney function.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or interact with dental anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Maintain a healthy weight to reduce breathing effort.
😴
Practice breathing exercises regularly.
💧
Stay up to date with vaccinations (flu, pneumonia).
🧘
Get adequate rest and sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have breathing difficulties. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine intake.
Stay well hydrated.
Avoid heavy, oily meals that can worsen breathing.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or restlessness. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your daily activities if taken as prescribed.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance and reduced effectiveness. Regular monitoring of heart rate, blood pressure, and liver and kidney function is recommended. Consult your doctor for periodic reviews.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

Inhaled medicines can provide rapid relief and may be used alongside or instead of oral medicines.

Evidence: Well-established
Pulmonary rehabilitation

Exercise and education programs can improve breathing and quality of life.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Ensure you are up to date with influenza and pneumococcal vaccinations, as respiratory infections can worsen asthma and COPD.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust your dosing schedule gradually under medical guidance. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with chronic asthma
He was prescribed this medicine for his asthma. He took it regularly with food and noticed significant improvement in his breathing within a week. He also avoided alcohol and caffeine, which helped reduce restlessness.
💡 Lesson: Taking this medicine with food and avoiding alcohol can improve tolerability and effectiveness.
👤 A 60-year-old woman with COPD
She started this medicine as part of her COPD treatment. She experienced mild nausea initially, but it subsided after taking it with meals. She emphasized the importance of not missing doses.
💡 Lesson: Consistency with dosing and taking with food can minimize side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes to 1 hour after taking it.

Q: Can I take it with food?

A: Yes, taking it with food can reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for doxonimar tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine controls symptoms but does not cure asthma. It must be used regularly as prescribed.
  • Myth: It is safe to double the dose if you miss one.
    Fact: Doubling the dose can lead to serious side effects. Follow the missed dose instructions.

🔄 Alternative Options

Generic Alternatives

  • Doxofylline 400 mg tablet

Brand Alternatives

  • Doxonimar tablet

📊 Comparison with Similar Medicines

[{"medicine":"Doxofylline","class":"Methylxanthine bronchodilator","common_uses":"Asthma, COPD","side_effects":"Nausea, headache, restlessness"},{"medicine":"Theophylline","class":"Methylxanthine bronchodilator","common_uses":"Asthma, COPD","side_effects":"Nausea, insomnia, arrhythmias"}]

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