Carbasma Tablet (Doxofylline): Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fast, irregular, or pounding heartbeat
- Seizures or convulsions
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Chest pain or severe shortness of breath
- Yellowing of skin or eyes (jaundice)
- Decreased urine output
- Severe nausea or vomiting that prevents keeping the medicine down
If experiencing severe symptoms, call emergency services immediately.
What is carbasma tablet used for?
This medicine contains doxofylline, a bronchodilator used to treat asthma and COPD. It works by relaxing airway muscles and reducing inflammation, making breathing easier. It is taken orally, usually twice daily, and should not be used for acute attacks.
- Generic Name: Doxofylline
- Manufacturer: Strides shasun Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 carbasma tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डॉक्सोफाइलिन नामक ब्रोंकोडाइलेटर है, जिसका उपयोग अस्थमा और सीओपीडी के इलाज में किया जाता है। यह श्वास नलियों की मांसपेशियों को आराम देकर सांस लेने में आसानी करती है। यह सूजन को भी कम करती है। यह दवा लंबे समय तक नियंत्रण के लिए है, तुरंत राहत के लिए नहीं। इसे डॉक्टर के बताए अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द, पेट दर्द और बेचैनी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि दिल की धड़कन तेज हो, दौरा पड़े या गंभीर एलर्जी हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गोली को चबाएं नहीं, पूरा निगल लें। इस दवा के साथ शराब न लें। यदि आपको हृदय, यकृत या गुर्दे की बीमारी है, या आप गर्भवती या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। तीव्र अस्थमा अटैक के लिए इस दवा का उपयोग न करें; रेस्क्यू इनहेलर पास रखें।
💊 carbasma tablet Uses & Benefits
[{"condition":"Bronchial asthma","description":"Helps control symptoms of asthma by relaxing airway muscles and reducing inflammation.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Improves breathing and reduces exacerbations in patients with COPD.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Bronchitis","description":"Sometimes used to relieve bronchospasm associated with bronchitis.","evidence":"Limited"}]
Primary treatment for: Bronchial asthma
Also treats: Chronic obstructive pulmonary disease (COPD), Bronchitis
📋 Drug Information
| Generic Name(s) | Doxofylline |
| Brand Name | Amril Plus 400mg Tablet |
| Manufacturer | Strides shasun Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Theophylline & its derivatives |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Doxofylline is a xanthine derivative that inhibits phosphodiesterase enzymes, primarily PDE3 and PDE4, leading to increased intracellular cyclic AMP levels. This results in relaxation of bronchial smooth muscle and bronchodilation. Additionally, it blocks adenosine receptors, which contributes to its bronchodilator and anti-inflammatory effects. Unlike other xanthines, doxofylline has a better safety profile with fewer cardiac and central nervous system side effects.
Mechanism Steps
💡 How to Take carbasma tablet
Strength: This medicine is available as an immediate-release tablet. The strength is not specified in the available information.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 400 mg twice daily or as prescribed by your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require a lower dose due to reduced renal and hepatic function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Dose adjustment may be required in patients with hepatic impairment. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 800 mg, but this may vary based on individual patient factors. Always follow your doctor's prescription. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of carbasma tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ciprofloxacin | Major | |
| Erythromycin | Major | |
| Propranolol | Moderate | |
| Phenytoin | Moderate | |
| Cimetidine | Minor |
🚨 Major Interactions
- Ciprofloxacin
- Erythromycin
⚡ Moderate Interactions
- Propranolol
- Phenytoin
🍷 Alcohol Interaction
Alcohol may increase the risk of central nervous system side effects such as dizziness and drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to doxofylline or other xanthines","Acute myocardial infarction","Severe cardiac arrhythmias","Severe hepatic impairment","Severe renal impairment","Children under 12 years of age (safety not established)"]
⚠️ Warnings & Precautions
["Do not use for acute asthma attacks; use a rescue inhaler.","Use with caution in patients with peptic ulcer disease.","Use with caution in patients with hyperthyroidism.","Use with caution in patients with epilepsy.","Avoid concurrent use with other xanthine derivatives.","Inform your doctor if you are taking any other medications."]
🤱 Lactation Safety
Not established from the available information. Doxofylline may pass into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, tachycardia, seizures, and cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. Avoid consuming alcohol while taking this medicine as it may increase the risk of side effects. Inform your doctor if you have heart disease, liver disease, kidney disease, or if you are pregnant or breastfeeding. Do not use this medicine to treat an acute asthma attack; always keep a rescue inhaler available. Regular follow-up with your doctor is important to monitor your condition and adjust the dose if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially cardiac effects. Dose adjustment may be necessary based on renal and hepatic function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor to review your asthma or COPD management. The safety of this medicine during pregnancy is not well established, and alternative treatments may be considered.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is beneficial, but avoid strenuous activity in cold or polluted air. Use your rescue inhaler if needed before exercise. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or restlessness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most desk jobs, but take precautions if your work involves physical exertion.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated, but regular monitoring of heart rate, liver and kidney function, and electrolytes may be required. It is not habit-forming. Do not stop taking it without consulting your doctor, as sudden discontinuation may worsen your respiratory condition.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement or be an alternative for long-term asthma control.
Evidence: Well-establishedOral medications that can help control asthma symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Ensure you are up to date with influenza and pneumococcal vaccinations, as respiratory infections can worsen asthma and COPD. Consult your doctor about the best timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Store away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 minutes to 1 hour after taking a dose, but its full benefits for controlling asthma or COPD may take several days to weeks of regular use.
A: Yes, but you must inform your doctor about all other medicines you are taking, as some may interact. Your doctor will adjust doses if needed.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor to weigh the benefits and risks.
🤔 Common Patient Concerns
🔄 Substitutes for carbasma tablet
View AllAlternative brands with exact same active ingredient:
-
doxonimar tabletEmcee Pharmaceuticals Pvt Ltd ₹38.46 50.6% COSTLIER
-
p dox tabletMarc Laboratories Pvt Ltd ₹55.31 116.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for immediate relief of asthma attacks.
Fact: This medicine is for long-term control and should not be used for acute attacks. A rescue inhaler is needed for sudden symptoms. - Myth: It is safe to take extra doses if symptoms worsen.
Fact: Taking more than the prescribed dose can lead to serious side effects. Always follow your doctor's instructions.
🔄 Alternative Options
Generic Alternatives
- Doxofylline
Brand Alternatives
- Doxofylline 400 mg tablet