doxikind-od tablet - Doxylamine (20mg) + Vitamin B6 (Pyridoxine) (20mg) medicine

doxikind-od tablet

4.6 (14 reviews)
๐Ÿญ Vhl Pharmaceuticals Private Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is doxikind-od tablet used for?

Act NVP Tablet (Doxylamine + Vitamin B6) is used to treat GASTRO INTESTINAL. It contains Doxylamine (20mg) + Vitamin B6 (Pyridoxine) (20mg), which Doxylamine: H1-receptor antagonist; Pyridoxine: cofactor for neurotransmitter sy. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Doxylamine + Vitamin B6
  • Manufacturer: Vhl Pharmaceuticals Private Limited
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š doxikind-od tablet Uses & Benefits

Nausea and vomiting in pregnancy.

Off-label uses: Insomnia, Allergic rhinitis

๐Ÿ“‹ Drug Information

Generic Name(s)Doxylamine + Vitamin B6
Brand NameAct NVP Tablet
ManufacturerVhl Pharmaceuticals Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntihistamine + Vitamin Supplement
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract.
DistributionDistributes widely in body tissues; crosses the placenta.
Protein BindingDoxylamine: ~50% bound to plasma proteins; Pyridoxine: minimal binding.
MetabolismDoxylamine: Hepatic via CYP450; Pyridoxine: Hepatic to pyridoxal phosphate.
Half-LifeDoxylamine: 10-12 hours; Pyridoxine: 15-20 days.
ExcretionDoxylamine: Renal (as metabolites); Pyridoxine: Renal (as metabolites).
BioavailabilityDoxylamine: ~70%; Pyridoxine: ~80%.
Onset of Action30-60 minutes.
Peak Plasma TimeDoxylamine: 2-3 hours; Pyridoxine: 1-2 hours.
Duration of Action4-6 hours.

How It Works

Doxylamine: H1-receptor antagonist; Pyridoxine: cofactor for neurotransmitter synthesis.

Mechanism Steps

1Doxylamine competitively blocks histamine at H1 receptors in the vomiting center.
2Pyridoxine acts as a cofactor for enzymes involved in neurotransmitter synthesis, reducing nausea.
3Combined effect reduces emetic signals and provides sedation.

๐Ÿ’ก How to Take doxikind-od tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of doxikind-od tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Constipation

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Urinary retention
  • Blurred vision

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
CNS depressants Major Enhanced sedation and respiratory depression
MAO inhibitors Major Increased anticholinergic and sedative effects
Anticholinergics Moderate Additive anticholinergic effects
Alcohol Moderate Increased sedation
Oral contraceptives Minor Reduced pyridoxine levels
Isoniazid Minor Reduced pyridoxine levels

๐Ÿšจ Major Interactions

  • CNS depressants
  • MAO inhibitors

โšก Moderate Interactions

  • Anticholinergics
  • Alcohol

โ„น๏ธ Minor Interactions

  • Oral contraceptives
  • Isoniazid

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase absorption

๐Ÿท Alcohol Interaction

Increased sedation and CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to doxylamine or pyridoxine; narrow-angle glaucoma; urinary retention; asthma attack.

๐Ÿ“Š Monitoring Parameters

Nausea/vomiting relief; sedation level; anticholinergic effects.

๐Ÿคฑ Lactation Safety

Use with caution; may cause drowsiness in infant.

๐Ÿ’Š Overdose Management

Symptomatic and supportive; activated charcoal if recent ingestion; monitor for CNS depression and anticholinergic effects.

โฐ Missed Dose

Take as soon as remembered unless near next dose; skip if close to next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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