donica-sr capsule
What is donica-sr capsule used for?
Artisid 50mg Capsule (Indomethacin) is used to treat PAIN ANALGESICS. It contains Indomethacin (75mg), which Non-selective inhibition of cyclooxygenase (COX-1 and COX-2) enzymes, reducing p. Always consult your doctor before use. Take as prescribed.
- Generic Name: Indomethacin
- Manufacturer: Ipca Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ donica-sr capsule Uses & Benefits
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gouty arthritis, bursitis, tendinitis, patent ductus arteriosus in neonates.
Off-label uses: Prevention of preterm labor, closure of patent ductus arteriosus in preterm infants, treatment of Bartter syndrome.
๐ Drug Information
| Generic Name(s) | Indomethacin |
| Brand Name | Artisid 50mg Capsule |
| Manufacturer | Ipca Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Non-selective inhibition of cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.
Mechanism Steps
๐ก How to Take donica-sr capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of donica-sr capsule
โ Common Side Effects
- Headache
- dizziness
- nausea
- vomiting
- dyspepsia
- abdominal pain
- constipation
- diarrhea
- heartburn
๐จ Serious Side Effects
- GI bleeding
- peptic ulcer
- perforation
- renal failure
- hypertension
- heart failure
- thrombotic events
- anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Hepatitis
- pancreatitis
- agranulocytosis
- aplastic anemia
- hemolytic anemia
- aseptic meningitis
- psychotic reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Aspirin | Major | Increased risk of GI ulceration and bleeding |
| Lithium | Major | Increased lithium levels and toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| ACE inhibitors | Major | Reduced antihypertensive effect; increased renal impairment risk |
| Diuretics | Major | Reduced diuretic effect; increased risk of renal failure |
| Anticoagulants | Moderate | Increased bleeding risk |
| Corticosteroids | Moderate | Increased risk of GI ulceration |
| SSRIs | Moderate | Increased bleeding risk |
| Digoxin | Moderate | Increased digoxin levels |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Antacids | Minor | Reduced absorption of indomethacin |
| Cholestyramine | Minor | Reduced absorption of indomethacin |
๐จ Major Interactions
- Warfarin
- Aspirin
- Lithium
- Methotrexate
- ACE inhibitors
- Diuretics
โก Moderate Interactions
- Anticoagulants
- Corticosteroids
- SSRIs
- Digoxin
- Cyclosporine
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to indomethacin or other NSAIDs; history of asthma, urticaria, or allergic reactions to NSAIDs; active peptic ulcer disease; severe renal or hepatic impairment; third trimester of pregnancy; perioperative pain in CABG surgery.
๐ Monitoring Parameters
Renal function, hepatic function, blood pressure, CBC, signs of GI bleeding, serum electrolytes.
๐คฑ Lactation Safety
Excreted in breast milk; avoid use due to potential adverse effects in infant.
๐ Overdose Management
Symptomatic and supportive care; induce emesis or gastric lavage; activated charcoal; monitor for GI bleeding, renal failure, and CNS depression.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for donica-sr capsule
View AllAlternative brands with exact same active ingredient (Indomethacin (75mg)):
-
indodrin 75mg capsule srCapsutab Drugs Pvt Ltd โน11.25 86% CHEAPER
-
ancap 75mg capsule srNoel Pharma India Pvt Ltd โน32.60 59.5% CHEAPER
-
microcid 75mg capsuleMicro Labs Ltd โน36.00 55.2% CHEAPER
-
indoflam 75mg capsule trZydus Cadila โน36.86 54.2% CHEAPER
-
artid 75mg capsule srDigmedi Pvt Ltd โน39.38 51% CHEAPER
-
indonet 75mg capsule srBennet Pharmaceuticals Limited โน63.28 21.3% CHEAPER
-
indoset 75mg capsule srStaneil Pharma โน70.31 12.6% CHEAPER
-
inmecin 75mg capsuleSterkem Pharma Pvt Ltd โน78.00 3% CHEAPER
-
ec 75mg tabletDokcare Life Sciences โน86.25 7.2% COSTLIER
-
indozyc 75mg capsule srBluewaterresearch โน86.25 7.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Helpful and effective medicine as per my experience. Always consult a doctor.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.