Acrid PD 30mg/20mg Capsule SR: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or cramping
- Chest pain or difficulty breathing
- Irregular heartbeat or palpitations
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output or swelling in legs
- Uncontrolled muscle spasms or tremors
If experiencing severe symptoms, call emergency services immediately.
What is dompax dsr 30mg/20mg capsule used for?
This medicine is a combination of Domperidone and Pantoprazole used to treat acid reflux, GERD, and associated nausea. It works by reducing stomach acid and improving gastric motility. It is usually taken once daily before breakfast.
- Generic Name: Domperidone (30mg) + Pantoprazole (20mg)
- Manufacturer: Ginpax Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dompax dsr 30mg/20mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और पैंटोप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, जीईआरडी, और इससे जुड़ी मतली और उल्टी के इलाज के लिए किया जाता है। यह पेट में एसिड का उत्पादन कम करती है और पेट की गति को बढ़ाती है, जिससे सीने में जलन, खट्टी डकार, और पेट फूलने जैसे लक्षणों में राहत मिलती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मुँह सूखना, दस्त, पेट दर्द, मतली और चक्कर आना शामिल हैं। कभी-कभी स्तन में दर्द या सूजन, और दूध का स्राव भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन मांसपेशियों में ऐंठन, बेचैनी, या दिल की धड़कन में गड़बड़ी हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं। इसे खाली पेट, नाश्ते से 30-60 मिनट पहले लेना सबसे अच्छा है। अगर पेट में जलन हो तो डॉक्टर की सलाह पर भोजन के साथ ले सकते हैं। शराब का सेवन न करें। चक्कर आने पर वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बिना डॉक्टर की सलाह के लंबे समय तक न लें।
💊 dompax dsr 30mg/20mg capsule Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by decreasing stomach acid production and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps relieve symptoms like bloating, early satiety, and upper abdominal discomfort by enhancing gastric motility and reducing acid.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"Improves gastric emptying and reduces nausea and vomiting in patients with delayed stomach emptying.","evidence":"Moderate"},{"condition":"Nausea and vomiting associated with acid peptic disorders","description":"Domperidone component helps control nausea and vomiting, while Pantoprazole treats underlying acid-related issues.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Refractory nausea and vomiting in palliative care","description":"Sometimes used off-label for symptom control in terminally ill patients, but evidence is limited.","evidence":"Limited"},{"condition":"Diabetic gastroparesis","description":"May be used off-label to improve gastric emptying in diabetic patients, but not FDA-approved for this indication.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastroparesis, Peptic ulcer disease, Nausea and vomiting
📋 Drug Information
| Generic Name(s) | Domperidone (30mg) + Pantoprazole (20mg) |
| Brand Name | dompax dsr 30mg/20mg capsule |
| Manufacturer | Ginpax Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Pantoprazole is a proton pump inhibitor that irreversibly inhibits the H+/K+-ATPase enzyme in gastric parietal cells, blocking the final step of acid secretion. This leads to a profound and long-lasting reduction in both basal and stimulated gastric acid production. Domperidone is a peripherally acting dopamine D2 receptor antagonist that blocks dopamine receptors in the chemoreceptor trigger zone and the gastrointestinal tract. This action enhances gastric motility, accelerates gastric emptying, and increases lower esophageal sphincter tone, thereby reducing nausea, vomiting, and reflux. Together, they provide both acid suppression and prokinetic effects.
Mechanism Steps
💡 How to Take dompax dsr 30mg/20mg capsule
Strength: Capsule containing Domperidone 30 mg and Pantoprazole 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken orally once daily, preferably on an empty stomach 30 to 60 minutes before breakfast. However, the dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to therapy. Do not self-adjust the dose. For GERD, treatment is typically continued for 4 to 8 weeks. For functional dyspepsia, it may be used for shorter periods. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially extrapyramidal reactions and QT prolongation. Use with caution and monitor closely. Dose adjustment may be necessary based on renal and hepatic function. |
| Renal Impairment | Domperidone is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). In mild to moderate renal impairment, use with caution and monitor for side effects. Pantoprazole does not require dose adjustment in renal impairment. |
| Hepatic Impairment | Domperidone is contraindicated in moderate to severe hepatic impairment. In mild hepatic impairment, use with caution and consider dose reduction. Pantoprazole dose should not exceed 40 mg per day in patients with severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Domperidone 30 mg + Pantoprazole 20 mg) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dompax dsr 30mg/20mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Warfarin | Major | |
| Methotrexate | Major | |
| Atazanavir | Major | |
| Clopidogrel | Moderate | |
| Fluconazole | Moderate | |
| Digoxin | Moderate | |
| Iron supplements | Moderate | |
| Antacids | Minor | |
| Sucralfate | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, ritonavir
- Warfarin
- Methotrexate
- Atazanavir, nelfinavir
⚡ Moderate Interactions
- Clopidogrel
- Fluconazole
- Digoxin
- Iron supplements
🍷 Alcohol Interaction
Alcohol can worsen acid reflux and increase the risk of gastrointestinal bleeding. It may also enhance the sedative effects of Domperidone, leading to increased drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Domperidone, Pantoprazole, or any component of the formulation","Moderate to severe hepatic impairment","Known long QT syndrome or family history of sudden cardiac death","Concomitant use with QT-prolonging drugs or potent CYP3A4 inhibitors","Gastrointestinal bleeding, mechanical obstruction, or perforation","Prolactin-releasing pituitary tumor (prolactinoma)","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease or risk factors for QT prolongation.","Avoid in patients with electrolyte imbalances (hypokalemia, hypomagnesemia).","Monitor for signs of extrapyramidal reactions, especially in elderly patients.","Long-term use may increase the risk of bone fractures, vitamin B12 deficiency, and gut infections.","Do not use for more than 12 weeks without medical supervision.","Use with caution in patients with mild to moderate hepatic impairment; dose adjustment may be needed.","Domperidone may increase prolactin levels; monitor for galactorrhea or gynecomastia.","Pantoprazole may mask symptoms of gastric malignancy; rule out malignancy before starting therapy."]
🤱 Lactation Safety
Domperidone is excreted in breast milk and may cause side effects in the infant. Pantoprazole is also excreted in breast milk but in small amounts. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause severe drowsiness, extrapyramidal symptoms, and QT prolongation. There is no specific antidote. Treatment is supportive and symptomatic. Gastric lavage may be considered if overdose is recent. Monitor ECG and electrolytes. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with water. It is best taken on an empty stomach, at least 30 to 60 minutes before a meal, to allow Pantoprazole to work effectively. However, if it causes stomach upset, you may take it with food after consulting your doctor. Avoid alcohol while taking this medicine, as it can worsen acid reflux and increase the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Inform your doctor if you have liver or kidney disease, heart rhythm problems, or if you are taking other medications, especially blood thinners, antifungals, or HIV drugs. Do not take this medicine for longer than prescribed without medical supervision. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of extrapyramidal side effects, QT prolongation, and bone fractures. Use with caution and monitor renal and hepatic function regularly. Dose adjustment may be needed.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy if you are taking this medicine. The safety of this combination during pregnancy is not well established. Your doctor may switch to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before any surgery. It may need to be stopped temporarily, especially before surgeries involving the gastrointestinal tract.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may interact with certain medications used during dental work, and dry mouth is a common side effect that can affect dental health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid vigorous exercise immediately after meals as it may worsen reflux. Listen to your body and stop if you feel dizzy or uncomfortable.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and avoid lying down immediately after meals.
🛑 When to Stop This Medicine
Do not stop this medicine abruptly without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Long-term use should be reviewed periodically.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to vitamin B12 deficiency, increased risk of bone fractures, and gut infections like Clostridium difficile. Domperidone may cause hyperprolactinemia with prolonged use. Regular monitoring of vitamin B12, magnesium, and bone health is recommended. Do not use for more than 12 weeks without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and avoiding trigger foods can significantly reduce GERD symptoms.
Evidence: Well-establishedOmeprazole, Rabeprazole, or Esomeprazole may be used as alternatives based on doctor's recommendation.
Evidence: Well-establishedRanitidine or Famotidine may be used for milder symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, long-term use of proton pump inhibitors may slightly reduce the immune response to certain vaccines. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling across time zones, continue taking it at the same time relative to your meals. For long trips, pack enough supply. Check customs regulations for carrying prescription medicines. Do not stop the medicine abruptly without consulting your doctor.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief from symptoms within a few days, but it may take 1 to 2 weeks for full effect.
A: It is best taken on an empty stomach, but if it causes stomach upset, you can take it with food after consulting your doctor.
A: Long-term use should be monitored by a doctor due to potential side effects like vitamin B12 deficiency and bone fractures.
A: Take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is advisable to avoid alcohol as it can worsen acid reflux and increase the risk of stomach bleeding.
🤔 Common Patient Concerns
🔄 Substitutes for dompax dsr 30mg/20mg capsule
View AllAlternative brands with exact same active ingredient:
-
letopan-dsr capsuleIntegra Life Sciences Pvt Ltd ₹65.63 12.5% CHEAPER
-
protera d 30mg/20mg capsuleLupin Ltd ₹66.96 10.7% CHEAPER
-
zenta dsr 30mg/20mg capsuleAbron Healthcare ₹70.31 6.3% CHEAPER
-
Rabisim D 30mg/20mg Capsule SRAlive Healthcare ₹70.31 6.3% CHEAPER
-
rabirow-dsr capsuleDrug For Life India Pvt Ltd ₹79.69 6.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure acid reflux permanently.
Fact: This medicine provides symptom relief but does not cure the underlying condition. Lifestyle changes and long-term management are often needed. - Myth: It is safe to take indefinitely without monitoring.
Fact: Long-term use requires periodic monitoring for side effects like vitamin B12 deficiency, bone fractures, and infections. - Myth: It can be taken with any other medication without interaction.
Fact: It interacts with several drugs, including blood thinners, antifungals, and HIV medications. Always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Pantoprazole generic capsules
Brand Alternatives
- Dompan
- Pantop-D
- Domperidone + Pantoprazole combinations