Abetin-nt 200 Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Irregular heartbeat or palpitations
- Severe dizziness or fainting
- Suicidal thoughts or self-harm ideation
- Yellowing of skin or eyes (jaundice)
- Severe rash with blisters or peeling skin
- Confusion or extreme drowsiness
If experiencing severe symptoms, call emergency services immediately.
What is doloneuron-nt 200 tablet used for?
This medicine is a combination of gabapentin and nortriptyline used to treat nerve pain. It works by calming overactive nerves and increasing pain-relieving chemicals in the brain. It is taken orally, usually once or twice daily, and should not be stopped suddenly.
- Generic Name: Gabapentin + Nortriptyline
- Manufacturer: Pulse Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 doloneuron-nt 200 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा गैबापेंटिन और नॉर्ट्रिप्टिलाइन का संयोजन है, जिसका उपयोग मुख्य रूप से तंत्रिका दर्द (न्यूरोपैथिक दर्द) के इलाज के लिए किया जाता है। यह मधुमेह से होने वाले तंत्रिका दर्द, दाद के बाद होने वाले दर्द, और अन्य पुराने तंत्रिका दर्द में राहत देती है। यह दवा दर्द के संकेतों को कम करके और मस्तिष्क में दर्द-निवारक रसायनों को बढ़ाकर काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, कब्ज, और वजन बढ़ना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, धड़कन अनियमित होना, या साँस लेने में कठिनाई हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें, इससे withdrawal के लक्षण हो सकते हैं। शराब का सेवन बिल्कुल न करें। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 doloneuron-nt 200 tablet Uses & Benefits
[{"condition":"Diabetic peripheral neuropathy","description":"Helps reduce burning, shooting, and tingling pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"Relieves persistent nerve pain that can occur after a shingles infection.","evidence":"Well-established"},{"condition":"Chronic neuropathic pain","description":"Used for various types of chronic nerve pain not responding to simple painkillers.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed to prevent migraines, though not a first-line treatment.","evidence":"Limited"},{"condition":"Fibromyalgia","description":"May be used to reduce widespread pain and improve sleep in some patients.","evidence":"Limited"}]
Primary treatment for: Neuropathic pain
Also treats: Diabetic neuropathy, Postherpetic neuralgia, Chronic musculoskeletal pain with neuropathic component
📋 Drug Information
| Generic Name(s) | Gabapentin + Nortriptyline |
| Brand Name | Acegaba NT 400mg/10mg Tablet |
| Manufacturer | Pulse Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Gabapentinoid + Tricyclic Antidepressant |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different but complementary actions. Gabapentin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the nervous system, reducing the release of excitatory neurotransmitters and calming overactive nerve signals. Nortriptyline increases the levels of serotonin and norepinephrine in the brain by blocking their reuptake, which helps modulate pain perception and improve mood and sleep. Together, they provide better relief for nerve pain than either alone.
Mechanism Steps
💡 How to Take doloneuron-nt 200 tablet
Strength: Each tablet contains gabapentin 200 mg and nortriptyline 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, or as directed by your doctor. The dose may be adjusted based on your response and tolerability. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially drowsiness, dizziness, and anticholinergic effects. Start with a lower dose and titrate slowly. Regular monitoring for falls and cognitive changes is advised. |
| Renal Impairment | Gabapentin requires dose reduction in renal impairment. Nortriptyline is primarily hepatically metabolized, but caution is advised. Consult your doctor for individualized dosing based on creatinine clearance. |
| Hepatic Impairment | Nortriptyline should be used with caution in hepatic impairment; dose reduction may be necessary. Gabapentin does not require hepatic adjustment. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is generally 2 tablets (gabapentin 400 mg + nortriptyline 20 mg) per day, but this must be individualized by a clinician. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of doloneuron-nt 200 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| Opioids | Major | |
| Benzodiazepines | Major | |
| Alcohol | Major | |
| Fluoxetine | Moderate | |
| Paroxetine | Moderate | |
| Quinidine | Moderate | |
| Rifampin | Moderate | |
| Carbamazepine | Moderate | |
| Antihypertensives | Moderate |
🚨 Major Interactions
- MAO inhibitors
- CNS depressants (e.g., opioids, benzodiazepines, alcohol)
- Anticholinergic drugs (e.g., antihistamines, antipsychotics)
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP2D6 inducers (e.g., rifampin, carbamazepine)
- Antihypertensives
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. It can significantly increase drowsiness, dizziness, and the risk of accidental injury. It may also worsen the sedative effects on breathing and coordination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to gabapentin, nortriptyline, or any component of the formulation","Concurrent use or within 14 days of MAO inhibitors","Acute recovery phase after myocardial infarction","Uncontrolled narrow-angle glaucoma","Severe liver disease","Breastfeeding without medical advice"]
⚠️ Warnings & Precautions
["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","Do not stop abruptly; withdrawal symptoms may occur. Taper gradually under medical supervision.","May increase suicidal thoughts; monitor mood closely, especially in young adults.","Use with caution in elderly patients due to increased risk of falls, confusion, and urinary retention.","May cause anticholinergic effects; use with caution in patients with glaucoma, benign prostatic hyperplasia, or constipation.","Avoid alcohol and other CNS depressants.","Inform your doctor if you have kidney or liver disease; dose adjustment may be needed."]
🤱 Lactation Safety
Gabapentin and nortriptyline are excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor after weighing benefits and risks.
💊 Overdose Management
Overdose can cause severe drowsiness, confusion, irregular heartbeat, seizures, and difficulty breathing. Seek emergency medical help immediately. Treatment is supportive and symptomatic; there is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs and cardiac rhythm.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop suddenly, as this can cause withdrawal symptoms such as anxiety, insomnia, and sweating. Avoid alcohol completely while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep all follow-up appointments and report any unusual symptoms promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to side effects such as confusion, falls, and urinary retention. Start with a lower dose and monitor closely. Regular review of kidney function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Both gabapentin and nortriptyline may pose risks to the fetus. Your doctor may consider alternative treatments or adjust the dose.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it may interact with anesthetic agents and increase sedation. It may need to be temporarily stopped before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause dry mouth and increase the risk of dental problems. It may also interact with local anesthetics or sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities requiring alertness until you know how this medicine affects you. Dizziness and drowsiness may increase the risk of falls. Start with light exercises and gradually increase as tolerated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and dizziness, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also affect concentration; take breaks and avoid multitasking if you feel impaired.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or no improvement after a reasonable trial, your doctor may decide to taper and stop it. Abrupt discontinuation can cause withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use may require periodic monitoring of kidney and liver function, especially in patients with pre-existing conditions. Dependence and withdrawal symptoms can occur if stopped abruptly. Regular follow-up with your doctor is essential to assess continued benefit and adjust the dose.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedHelps manage chronic pain and improve coping skills.
Evidence: ModerateMay provide additional pain relief for some patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Check local customs regulations for controlled substances, as nortriptyline may be regulated in some countries.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief may begin within a few days, but full effect can take 2-4 weeks. Continue taking it as prescribed.
A: No, do not stop suddenly. Consult your doctor to taper the dose gradually to avoid withdrawal symptoms.
A: Consult your doctor before taking any other painkillers, as interactions may occur.
🤔 Common Patient Concerns
🔄 Substitutes for doloneuron-nt 200 tablet
View AllAlternative brands with exact same active ingredient:
-
abetin-nt 200 tabletNumedix Life Sciences ₹130.00 27.8% CHEAPER
-
gabapin nt 200 tabletIntas Pharmaceuticals Ltd ₹173.44 3.6% CHEAPER
-
gabator nt 200 tabletTorrent Pharmaceuticals Ltd ₹284.20 57.9% COSTLIER
-
gabapax nt 200mg/10mg tabletAlteus Biogenics Pvt Ltd ₹307.40 70.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a simple painkiller for any type of pain.
Fact: It is specifically for nerve pain and is not effective for ordinary headaches or muscle strains. - Myth: You can stop taking this medicine whenever you feel better.
Fact: Stopping suddenly can cause withdrawal symptoms. Always taper under medical supervision. - Myth: It is safe to drink alcohol while on this medicine.
Fact: Alcohol increases drowsiness and dizziness and should be avoided completely.
🔄 Alternative Options
Generic Alternatives
- Gabapentin 200 mg + Nortriptyline 10 mg tablet (generic versions available)
Brand Alternatives
- Gabapentin 200 mg + Nortriptyline 10 mg tablet (various brands)