Arixib 90 Tablet: Uses, Side Effects, Dosage, and Safety Guide
What is arixib 90 tablet used for?
Arixib 90 tablet contains Etoricoxib 90 mg, a selective COX-2 inhibitor used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, and acute gout. It is taken orally once daily as prescribed.
- Generic Name: Etoricoxib
- Manufacturer: Pulse Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 arixib 90 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरिकॉक्सिब 90 मिलीग्राम युक्त एक प्रिस्क्रिप्शन टैबलेट है। इसका उपयोग ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस, और तीव्र गाउट में दर्द और सूजन को कम करने के लिए किया जाता है। यह दांत की सर्जरी के बाद होने वाले दर्द के इलाज के लिए भी उपयोग की जाती है।
साइड इफेक्ट्स: सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, पेट दर्द, अपच, मतली और दस्त शामिल हैं। गंभीर दुष्प्रभावों में पेट के अल्सर या रक्तस्राव, गुर्दे की समस्याएं, यकृत की समस्याएं, और उच्च रक्तचाप शामिल हो सकते हैं।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। खुराक या उपचार की अवधि से अधिक न लें। इसे पानी के साथ लें, भोजन के साथ या बिना। इस दवा के साथ शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से परामर्श लें।
💊 arixib 90 tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"This medicine is used to relieve pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in joints caused by osteoarthritis."},{"condition":"Rheumatoid arthritis","description":"This medicine helps reduce pain and inflammation in rheumatoid arthritis."},{"condition":"Acute gouty arthritis","description":"This medicine is used for short-term relief of pain and inflammation during acute gout attacks."},{"condition":"Acute musculoskeletal pain","description":"This medicine may be used for short-term management of moderate musculoskeletal pain."},{"condition":"Postoperative dental pain","description":"This medicine is used for short-term relief of moderate pain following dental surgery."}]
Off-label uses: []
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Acute gouty arthritis, Postoperative dental pain, Acute musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Etoricoxib |
| Brand Name | Arixib 90 Tablet |
| Manufacturer | Pulse Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's -Selective COX-2 Inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature (below 30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Etoricoxib selectively inhibits the enzyme cyclooxygenase-2 (COX-2), which is responsible for the production of prostaglandins that mediate pain, inflammation, and fever. By blocking COX-2, this medicine reduces the formation of these prostaglandins, thereby decreasing pain and swelling. Unlike non-selective NSAIDs, it has less effect on COX-1, which is involved in protecting the stomach lining and maintaining normal platelet function.
Mechanism Steps
💡 How to Take arixib 90 tablet
Strength: 90 mg
Dosage Information
| Adult Dosage | The usual adult dose for osteoarthritis and rheumatoid arthritis is 60 mg once daily. For acute gouty arthritis, the dose is 120 mg once daily for the shortest duration. For postoperative dental pain, the dose is 90 mg once daily for up to 7 days. The dose may be adjusted based on the condition and response. Do not exceed the recommended dose. |
| Pediatric Dosage | The safety and efficacy of etoricoxib in children under 16 years of age have not been established. Dose must be determined by a qualified clinician based on indication, age, weight, and renal/hepatic function. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but caution is advised due to increased risk of cardiovascular, kidney, and gastrointestinal side effects. Use the lowest effective dose for the shortest duration. |
| Renal Impairment | In patients with mild to moderate kidney impairment (creatinine clearance 30-60 mL/min), no dose adjustment is needed. In severe kidney impairment (creatinine clearance <30 mL/min), etoricoxib is contraindicated. |
| Hepatic Impairment | In patients with mild liver impairment (Child-Pugh A), no dose adjustment is needed. In moderate liver impairment (Child-Pugh B), the dose should not exceed 60 mg once daily. In severe liver impairment (Child-Pugh C), etoricoxib is contraindicated. |
| Maximum Daily Dose | The maximum recommended daily dose is 120 mg for acute gouty arthritis, and 90 mg for other indications. Do not exceed 120 mg per day. |
Dosage Timeline
⚠️ Side Effects of arixib 90 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Minor | ||
| Minor | ||
| Minor | ||
| Minor | ||
| Minor |
🚨 Major Interactions
- Warfarin and other anticoagulants
- ACE inhibitors and angiotensin receptor blockers (ARBs)
- Diuretics
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Corticosteroids
- Other NSAIDs
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Alcohol may increase the risk of gastrointestinal bleeding and ulcers when taken with etoricoxib. It is advisable to avoid alcohol while taking this medicine.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to etoricoxib or any component of the formulation.","Active peptic ulcer or gastrointestinal bleeding.","Severe heart failure (NYHA class II-IV).","Uncontrolled hypertension.","Established ischemic heart disease, peripheral arterial disease, or cerebrovascular disease.","Severe liver impairment (Child-Pugh C).","Severe kidney impairment (creatinine clearance
⚠️ Warnings & Precautions
[{"warning":"Cardiovascular risk","reason":"Etoricoxib may increase the risk of serious cardiovascular events.","action":"Use the lowest effective dose for the shortest duration. Avoid in patients with established cardiovascular disease."},{"warning":"Gastrointestinal risk","reason":"Etoricoxib can cause ulcers and bleeding in the stomach and intestines.","action":"Monitor for signs of bleeding. Consider gastroprotective agents in high-risk patients."},{"warning":"Kidney risk","reason":"Etoricoxib can impair kidney function.","action":"Monitor kidney function. Avoid in severe kidney disease."},{"warning":"Liver risk","reason":"Etoricoxib can cause liver injury.","action":"Monitor liver enzymes. Discontinue if signs of liver failure occur."},{"warning":"Hypertension","reason":"Etoricoxib can increase blood pressure.","action":"Monitor blood pressure. Use with caution in patients with hypertension."},{"warning":"Allergic reactions","reason":"Serious allergic reactions can occur.","action":"Discontinue and seek immediate medical help if allergic symptoms occur."}]
🤱 Lactation Safety
Etoricoxib is excreted in human milk. It is not recommended during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor.
💊 Overdose Management
Overdose of etoricoxib may cause symptoms such as nausea, vomiting, stomach pain, and drowsiness. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take the tablet with a glass of water, with or without food. Avoid alcohol while taking this medicine as it may increase the risk of stomach bleeding. Inform your doctor if you have a history of stomach ulcers, heart disease, high blood pressure, kidney or liver problems, or asthma. Do not use this medicine if you are pregnant, especially in the third trimester, or if you are breastfeeding without consulting your doctor. Regular monitoring of blood pressure, kidney function, and liver function may be required during long-term use. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.
🔄 Substitutes for arixib 90 tablet
View AllAlternative brands with exact same active ingredient:
-
zeexib 90 tabletZeelab Pharmacy Pvt Ltd ₹27.00 81.7% CHEAPER
-
etoridoc 90mg tabletMorepen Laboratories Ltd ₹29.30 80.1% CHEAPER
-
etrolup 90mg tabletLupin Ltd ₹30.11 79.5% CHEAPER
-
stayhappi etoricoxib 90mg tabletSarvagunaushdhi Pvt Ltd ₹37.50 74.5% CHEAPER
-
davaindia etoricoxib 90mg tabletDavaindia Generic Pharmacy ₹38.00 74.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Arixib 90 tablet is a steroid.
Fact: Arixib 90 tablet is not a steroid. It is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits COX-2. - Myth: Arixib 90 tablet can be taken for any type of pain.
Fact: Arixib 90 tablet is indicated for specific inflammatory conditions and should only be used as prescribed by a doctor. - Myth: Arixib 90 tablet is safe to take without a prescription.
Fact: Arixib 90 tablet is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Etoricoxib 90 mg tablet