Diclofenac Sodium & Paracetamol 50mg/500mg Tablet: Complete Information
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is dicloact plus 50 mg/500 mg tablet used for?
This medicine is a combination of Diclofenac Sodium 50 mg and Paracetamol 500 mg used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain. Take it with food, do not exceed 3 tablets in 24 hours, and avoid alcohol.
- Generic Name: Diclofenac (50mg) + Paracetamol (500mg)
- Manufacturer: Cadila Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dicloact plus 50 mg/500 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइक्लोफेनाक सोडियम 50 मिलीग्राम और पैरासिटामोल 500 मिलीग्राम का संयोजन है। इसका उपयोग तीव्र दर्द और सूजन जैसे मांसपेशियों के दर्द, जोड़ों के दर्द, दांत दर्द, मासिक धर्म के दर्द और सर्जरी के बाद के दर्द के लिए किया जाता है। यह दवा सूजन पैदा करने वाले प्रोस्टाग्लैंडिन को कम करके काम करती है। इसे भोजन के साथ लें और 24 घंटे में 3 गोलियों से अधिक न लें। शराब का सेवन न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, एलर्जी प्रतिक्रिया, गुर्दे की समस्या, यकृत की क्षति और हृदय संबंधी घटनाएं शामिल हैं। यदि आपको काला मल, खून की उल्टी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब में कमी जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन या दूध के साथ लें ताकि पेट में जलन न हो। निर्धारित खुराक से अधिक न लें। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की क्षति का खतरा बढ़ जाता है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, यकृत, या हृदय की समस्या है, तो डॉक्टर से परामर्श लें। चक्कर आ सकते हैं, इसलिए वाहन चलाने से बचें।
💊 dicloact plus 50 mg/500 mg tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective for relief of toothache and pain following dental extraction.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Provides symptomatic relief of pain and stiffness in osteoarthritis, but only for short-term use.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"May be used for short-term relief of pain and inflammation in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Renal colic","description":"May be used off-label for pain relief in kidney stones, but requires medical supervision.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Dysmenorrhea, Post-operative pain, Dental pain
📋 Drug Information
| Generic Name(s) | Diclofenac (50mg) + Paracetamol (500mg) |
| Brand Name | dicloact plus 50 mg/500 mg tablet |
| Manufacturer | Cadila Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Diclofenac Sodium is a non-steroidal anti-inflammatory drug that reversibly inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane. This results in reduced inflammation, pain, and fever. Paracetamol (acetaminophen) acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis with minimal anti-inflammatory effects. The combination provides enhanced pain relief through different pathways.
Mechanism Steps
💡 How to Take dicloact plus 50 mg/500 mg tablet
Strength: Tablet containing Diclofenac Sodium 50 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Diclofenac Sodium 50 mg + Paracetamol 500 mg) taken orally every 6 to 8 hours as needed for pain relief, not exceeding 3 tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration. Take with food or milk to reduce stomach upset. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Avoid use in severe renal impairment (eGFR <30 mL/min). Consult a doctor for appropriate dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid use in severe hepatic impairment. Consult a doctor for appropriate dosing. |
| Maximum Daily Dose | Maximum daily dose: 3 tablets (Diclofenac Sodium 150 mg + Paracetamol 1500 mg) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dicloact plus 50 mg/500 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Lithium | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, aspirin)
- Methotrexate
- ACE inhibitors and angiotensin receptor blockers
- Diuretics
⚡ Moderate Interactions
- Corticosteroids
- Selective serotonin reuptake inhibitors (SSRIs)
- Lithium
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage, especially with paracetamol. It may also enhance the central nervous system effects such as dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to diclofenac, paracetamol, or any NSAID","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure, ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease","Severe hepatic impairment or active liver disease","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Take with food or milk to reduce gastrointestinal irritation.","Avoid alcohol consumption.","Do not exceed recommended dose or duration.","Use with caution in elderly patients due to increased risk of side effects.","Use with caution in patients with dehydration, kidney disease, or heart failure.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use concurrently with other NSAIDs or paracetamol-containing products.","Consult doctor if symptoms persist beyond 7 days or worsen."]
🤱 Lactation Safety
Diclofenac and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding, kidney failure, and central nervous system effects due to diclofenac. Seek immediate medical attention. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine with food or milk to reduce stomach upset. Do not exceed the recommended dose or duration of treatment. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding and liver damage. Do not take other NSAIDs or paracetamol-containing products simultaneously to prevent overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat. Do not use after the expiry date. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose; do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning pregnancy. Diclofenac is generally avoided in the third trimester. Paracetamol is considered relatively safe but should be used at the lowest effective dose for the shortest duration.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but it can increase the risk of bleeding. Inform your surgeon if you are taking this medicine before surgery. It may need to be stopped before certain procedures.
🦷 Dental Procedures
This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may increase pain while taking this medicine. Gentle stretching and low-impact exercises are generally safe. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly impact desk work.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly if you are on long-term therapy without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events. It is not recommended for chronic use without regular monitoring. If long-term therapy is necessary, your doctor may monitor liver and kidney function, blood counts, and blood pressure. Use the lowest effective dose for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help relieve localized pain and inflammation.
Evidence: LimitedSome evidence for pain relief in certain conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines. Do not leave it in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30-60 minutes after taking it orally.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: Do not take with other NSAIDs or paracetamol-containing products without consulting your doctor, as it can increase the risk of side effects.
A: Do not exceed 3 tablets in 24 hours unless directed by your doctor.
A: No, alcohol should be avoided as it increases the risk of stomach bleeding and liver damage.
🤔 Common Patient Concerns
🔄 Substitutes for dicloact plus 50 mg/500 mg tablet
View AllAlternative brands with exact same active ingredient:
-
diclot plus 50 mg/500 mg tabletGlenmark Pharmaceuticals Ltd ₹3.43 16.3% CHEAPER
-
dicloross 50 mg/500 mg tabletShreya Life Sciences Pvt Ltd ₹3.50 14.6% CHEAPER
-
dicoliv plus 50 mg/500 mg tabletInd Swift Laboratories Ltd ₹4.22 2.9% COSTLIER
-
diclopil plus 50 mg/500 mg tabletPsychotropics India Ltd ₹4.33 5.6% COSTLIER
-
emergesic 50 mg/500 mg tabletAnglo-French Drugs & Industries Ltd ₹4.59 12% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: It is intended for short-term use only. Long-term use increases the risk of gastrointestinal, cardiovascular, and kidney side effects. - Myth: It can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach upset. - Myth: It is safe to take with alcohol.
Fact: Alcohol increases the risk of stomach bleeding and liver damage. Avoid alcohol. - Myth: It can be combined with other painkillers.
Fact: Combining with other NSAIDs or paracetamol can lead to overdose and serious side effects. Consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Diclofenac Sodium 50 mg + Paracetamol 500 mg Tablet (various manufacturers)
Brand Alternatives
- Blue Cross Laboratories Ltd's Diclofenac Sodium & Paracetamol 50mg/500mg Tablet