Gutrex D 2.5mg/5mg Tablet: Complete Information
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or cramping that does not improve
- Blood in stool or vomit
- Difficulty breathing or shortness of breath
- Severe dizziness or fainting
- Confusion, hallucinations, or memory problems
- Signs of allergic reaction: rash, itching, swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or inability to urinate
If experiencing severe symptoms, call emergency services immediately.
What is depcon tablet used for?
This medicine is a combination of clidinium (an antispasmodic) and chlordiazepoxide (a benzodiazepine) used for short-term relief of irritable bowel syndrome symptoms such as abdominal pain, cramping, and anxiety. It is taken orally, usually three to four times daily before meals and at bedtime, and should not be used long-term due to risk of dependence.
- Generic Name: Clidinium (2.5mg) + Chlordiazepoxide (5mg)
- Manufacturer: Unisharp Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 depcon tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लिडिनियम और क्लोरडायजेपॉक्साइड का संयोजन है, जिसका उपयोग इरिटेबल बाउल सिंड्रोम (IBS) के लक्षणों जैसे पेट दर्द, ऐंठन, सूजन और चिंता के अल्पकालिक उपचार के लिए किया जाता है। यह पेट की मांसपेशियों को आराम देती है और चिंता को कम करती है। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें और लंबे समय तक न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, धुंधली दृष्टि, नींद आना, चक्कर आना, कब्ज और पेशाब में रुकावट शामिल हैं। गंभीर दुष्प्रभावों में भ्रम, याददाश्त में कमी, और निर्भरता हो सकती है। यदि आपको गंभीर पेट दर्द, सांस लेने में कठिनाई, या एलर्जी के लक्षण हों तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न बढ़ाएं और न ही लंबे समय तक लें। दवा लेने के बाद वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें। यदि आपको यकृत या गुर्दे की बीमारी है, या आप गर्भवती हैं, तो डॉक्टर को बताएं। दवा बंद करने से पहले डॉक्टर से सलाह लें।
💊 depcon tablet Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS)","description":"Relieves abdominal pain, cramping, bloating, and altered bowel habits, particularly when associated with anxiety.","evidence":"Well-established for short-term use"},{"condition":"Gastrointestinal spasm","description":"Helps relax smooth muscles of the gastrointestinal tract to reduce spasm-related pain.","evidence":"Established"},{"condition":"Anxiety associated with gastrointestinal disorders","description":"The chlordiazepoxide component helps reduce anxiety that may exacerbate gastrointestinal symptoms.","evidence":"Established for short-term use"}]
Off-label uses: [{"condition":"Peptic ulcer disease","description":"Sometimes used as an adjunct to reduce spasm and anxiety, though not a primary treatment.","evidence":"Limited"},{"condition":"Biliary dyskinesia","description":"May be used off-label to relieve biliary tract spasm.","evidence":"Limited"}]
Primary treatment for: Irritable bowel syndrome
Also treats: Gastrointestinal spasm, Anxiety associated with gastrointestinal disorders
📋 Drug Information
| Generic Name(s) | Clidinium (2.5mg) + Chlordiazepoxide (5mg) |
| Brand Name | depcon tablet |
| Manufacturer | Unisharp Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Clidinium bromide is a quaternary ammonium antimuscarinic agent that inhibits muscarinic acetylcholine receptors on smooth muscle cells in the gastrointestinal tract, leading to reduced motility and spasm. Chlordiazepoxide is a benzodiazepine that binds to the benzodiazepine site on the GABA-A receptor, enhancing the inhibitory effects of GABA, which results in anxiolytic, sedative, and muscle-relaxant effects. Together, they address both the spastic and anxiety components of functional gastrointestinal disorders.
Mechanism Steps
💡 How to Take depcon tablet
Strength: Tablet containing clidinium 2.5 mg and chlordiazepoxide 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally three to four times daily, before meals and at bedtime. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, and renal and hepatic function. Do not exceed the prescribed dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of benzodiazepines and anticholinergics. Start with a lower dose and titrate slowly. Use with caution due to increased risk of confusion, falls, and cognitive impairment. |
| Renal Impairment | Dose adjustment may be necessary in patients with renal impairment. Chlordiazepoxide metabolites are renally excreted; consult a clinician for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Chlordiazepoxide is extensively metabolized in the liver; dose reduction may be required. Avoid in severe liver disease. |
| Maximum Daily Dose | The maximum recommended daily dose is not established from available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of depcon tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Opioids | Major | |
| Alcohol | Major | |
| Cimetidine | Moderate | |
| MAO inhibitors | Major | |
| Anticholinergics | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor | |
| Rifampicin | Minor |
🚨 Major Interactions
- CNS depressants (e.g., opioids, alcohol, barbiturates)
- MAO inhibitors
- Anticholinergic drugs (e.g., atropine, antihistamines, tricyclic antidepressants)
⚡ Moderate Interactions
- Cimetidine
- Oral contraceptives
- Antacids
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine. Alcohol enhances the CNS depressant effects of chlordiazepoxide, leading to increased drowsiness, dizziness, impaired judgment, and risk of respiratory depression. It can also worsen anticholinergic side effects such as dry mouth and constipation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clidinium, chlordiazepoxide, or any component of the formulation","Glaucoma (angle-closure)","Urinary retention","Myasthenia gravis","Severe liver disease","Pregnancy (especially first and third trimesters)","Breastfeeding","Children under 6 years of age","Severe respiratory insufficiency","Sleep apnea"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness and impair ability to drive or operate machinery. Avoid these activities until you know how it affects you.","Do not consume alcohol or other CNS depressants while taking this medicine.","Use with caution in elderly patients due to increased risk of confusion, falls, and cognitive impairment.","Prolonged use can lead to physical and psychological dependence. Use for the shortest duration possible.","Do not stop abruptly after prolonged use; taper gradually under medical supervision to avoid withdrawal symptoms.","Use with caution in patients with hepatic or renal impairment; dose adjustment may be necessary.","May exacerbate symptoms of myasthenia gravis, prostatic hyperplasia, and hyperthyroidism.","Anticholinergic effects can cause heat intolerance; avoid exposure to high temperatures.","May cause paradoxical excitement, agitation, or hallucinations, especially in elderly or psychiatric patients.","Not recommended for use in children under 6 years of age."]
🤱 Lactation Safety
Chlordiazepoxide is excreted in breast milk and may cause sedation, poor feeding, and weight loss in the infant. Clidinium may also pass into breast milk. This medicine is not recommended during breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe anticholinergic symptoms (dry mouth, blurred vision, tachycardia, urinary retention, ileus) and benzodiazepine toxicity (drowsiness, confusion, coma, respiratory depression). Management includes supportive care, gastric lavage if within 1-2 hours of ingestion, activated charcoal, and monitoring of vital signs. Flumazenil, a benzodiazepine antagonist, may be used cautiously but can precipitate seizures in dependent patients. Physostigmine may be considered for severe anticholinergic toxicity. Seek immediate emergency medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it for longer than recommended. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine as it can increase drowsiness and impair judgment. Inform your doctor if you have a history of substance abuse, liver or kidney disease, or mental health conditions. Do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of benzodiazepines and anticholinergics. They are at higher risk of confusion, falls, and cognitive impairment. Use with caution, starting at a lower dose and monitoring closely.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to discuss alternative treatments. Effective contraception should be used while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it can interact with anesthetic agents and increase the risk of respiratory depression. It may need to be stopped before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it can cause dry mouth and increase the risk of dental caries. It may also interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid strenuous activities if you experience dizziness or drowsiness. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine abruptly without consulting your doctor. Your doctor will gradually reduce the dose to prevent withdrawal symptoms. If you experience side effects or your symptoms improve, consult your doctor before making any changes.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation. It may also cause cognitive impairment, especially in the elderly. Regular monitoring of liver function and mental status is recommended. Use for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A low-FODMAP diet or high-fiber diet can help manage IBS symptoms.
Evidence: Well-establishedYoga, meditation, and cognitive-behavioral therapy can reduce anxiety and improve IBS symptoms.
Evidence: Well-establishedCertain probiotic strains may help balance gut bacteria and reduce symptoms.
Evidence: Emerging💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Be aware of customs regulations regarding prescription medications in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antispasmodic effects may begin within 30-60 minutes, while the anxiolytic effects may take a few days to fully manifest.
A: Always inform your doctor about all medications you are taking, as this medicine can interact with many drugs, including CNS depressants, MAO inhibitors, and anticholinergics.
A: Take it as soon as you remember if it's not too close to the next dose. Otherwise, skip it and continue with your regular schedule. Do not double dose.
A: This medicine can cause drowsiness and dizziness. Avoid driving or operating machinery until you know how it affects you.
A: No, do not stop abruptly as it can cause withdrawal symptoms. Consult your doctor for a gradual tapering plan.
🤔 Common Patient Concerns
🔄 Substitutes for depcon tablet
View AllAlternative brands with exact same active ingredient:
-
libopil 5 mg/2.5 mg tabletPsychotropics India Ltd ₹5.33 79.7% CHEAPER
-
cromide forte 2.5 mg/5 mg/10 mg tabletLeeford Healthcare Ltd ₹7.50 71.4% CHEAPER
-
libnam 5 mg/2.5 mg tabletMankind Pharma Ltd ₹8.20 68.8% CHEAPER
-
libsana 5mg/2.5mg tabletRyon Pharma ₹9.38 64.3% CHEAPER
-
cromide 5mg/2.5mg tabletLeeford Healthcare Ltd ₹11.72 55.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for IBS.
Fact: This medicine is intended for short-term use only due to the risk of dependence and tolerance associated with chlordiazepoxide. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be strictly avoided as it increases the risk of severe drowsiness, respiratory depression, and other CNS effects. - Myth: This medicine is a cure for IBS.
Fact: This medicine provides symptomatic relief but does not cure IBS. Lifestyle and dietary modifications are also important.
🔄 Alternative Options
Generic Alternatives
- Clidinium + Chlordiazepoxide combination generics
Brand Alternatives
- Gutrex D 2.5mg/5mg/10mg Tablet