Dasatinib 70mg Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe headache, confusion, or vision changes
- Shortness of breath or difficulty breathing
- Chest pain or palpitations
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Fever above 100.4°F (38°C) or chills
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is daslemia 70 tablet used for?
This medicine is a targeted cancer medicine containing dasatinib 70 mg. It is used to treat Philadelphia chromosome-positive chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) in adults. It works by blocking abnormal proteins that drive cancer cell growth. It is taken orally once daily, with or without food, under the supervision of a cancer specialist.
- Generic Name: Dasatinib (70mg)
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 daslemia 70 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डैसैटिनिब 70 मिलीग्राम युक्त एक मौखिक गोली है, जिसका उपयोग वयस्कों में फिलाडेल्फिया क्रोमोसोम-पॉजिटिव क्रोनिक मायलॉइड ल्यूकेमिया (सीएमएल) और फिलाडेल्फिया क्रोमोसोम-पॉजिटिव एक्यूट लिम्फोब्लास्टिक ल्यूकेमिया (एएलएल) के इलाज के लिए किया जाता है। यह एक टार्गेटेड कैंसर दवा है जो कैंसर कोशिकाओं के विकास को रोकने वाले असामान्य प्रोटीन को अवरुद्ध करती है। यह दवा केवल कैंसर रोग विशेषज्ञ की देखरेख में ही ली जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, थकान, सिरदर्द, मतली, उल्टी, मांसपेशियों और जोड़ों में दर्द, त्वचा पर दाने और शरीर में सूजन शामिल हैं। गंभीर दुष्प्रभावों में गंभीर रक्तस्राव, फेफड़ों या हृदय के आसपास तरल पदार्थ जमा होना, हृदय की लय में गड़बड़ी, लीवर की क्षति और ट्यूमर लिसिस सिंड्रोम शामिल हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य कैंसर विशेषज्ञ की देखरेख में ही लेनी चाहिए। डॉक्टर की सलाह के बिना दवा शुरू, बंद या उसकी खुराक न बदलें। इसे हर दिन एक ही समय पर लें, भोजन के साथ या बिना। ग्रेपफ्रूट और ग्रेपफ्रूट जूस से बचें क्योंकि यह दवा के स्तर को बढ़ा सकते हैं। गोली को पूरा निगलें, चबाएं या तोड़ें नहीं। यदि खुराक छूट जाए तो उसी दिन याद आने पर ले लें, लेकिन अगली खुराक का समय नजदीक हो तो छूटी हुई खुराक छोड़ दें। एक साथ दो खुराक न लें। उपचार के दौरान और अंतिम खुराक के कम से कम 30 दिन बाद तक प्रभावी गर्भनिरोधक का उपयोग करें। स्तनपान न करें। नियमित रक्त परीक्षण और हृदय की निगरानी के लिए सभी अपॉइंटमेंट लें।
💊 daslemia 70 tablet Uses & Benefits
[{"condition":"Philadelphia chromosome-positive chronic myeloid leukemia (CML) in chronic phase","description":"Used in adults who are newly diagnosed or resistant or intolerant to prior therapy including imatinib.","evidence":"Well-established"},{"condition":"Philadelphia chromosome-positive chronic myeloid leukemia (CML) in accelerated or blast phase","description":"Used in adults with advanced phase disease who are resistant or intolerant to other treatments.","evidence":"Well-established"},{"condition":"Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL)","description":"Used in adults with resistance or intolerance to prior therapies.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gastrointestinal stromal tumors (GIST)","description":"Sometimes used off-label in patients with specific mutations after failure of standard treatments.","evidence":"Limited"},{"condition":"Systemic mastocytosis","description":"Rarely used off-label in aggressive forms of this disease.","evidence":"Limited"}]
Primary treatment for: Philadelphia chromosome-positive chronic myeloid leukemia (CML)
Also treats: Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL)
📋 Drug Information
| Generic Name(s) | Dasatinib (70mg) |
| Brand Name | daslemia 70 tablet |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Tyrosine kinase inhibitors |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep in the original container, tightly closed, away from moisture and heat. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | Not established from the available information. Refer to the product packaging for the expiration date. |
| WHO Guideline | Not established from the available information. Refer to current WHO guidelines for CML and ALL management. |
| ICMR Guideline | Not established from the available information. Refer to ICMR guidelines for cancer management. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a potent inhibitor of multiple tyrosine kinases, including BCR-ABL, SRC family kinases, c-KIT, and PDGFR. By binding to the ATP-binding site of these enzymes, it blocks the signals that drive the growth and survival of cancer cells, particularly those carrying the Philadelphia chromosome. This leads to inhibition of cell proliferation and induction of apoptosis in leukemic cells.
Mechanism Steps
💡 How to Take daslemia 70 tablet
Strength: This medicine is available as a 70 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for chronic phase CML is 100 mg once daily, and for accelerated or blast phase CML or Ph+ ALL is 140 mg once daily. The 70 mg tablet is typically used as part of a dose reduction strategy or for specific indications as determined by the treating oncologist. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | No specific dose adjustment is recommended for elderly patients based on age alone. However, elderly patients may be more susceptible to side effects such as fluid retention and fatigue. Close monitoring is advised. |
| Renal Impairment | No dose adjustment is required for patients with mild to moderate renal impairment. There is limited experience in patients with severe renal impairment; use with caution and monitor closely. |
| Hepatic Impairment | Dose reduction is recommended for patients with moderate to severe hepatic impairment. Consult the prescribing information for specific recommendations. Monitor liver function closely. |
| Maximum Daily Dose | The maximum recommended daily dose is 140 mg once daily for accelerated or blast phase CML and Ph+ ALL, and 100 mg once daily for chronic phase CML. Doses above these are not recommended. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of daslemia 70 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampin | Major | |
| Warfarin | Major | |
| Amiodarone | Major | |
| Omeprazole | Moderate | |
| Ibuprofen | Moderate | |
| St. John's wort | Major | |
| Clarithromycin | Major | |
| Phenytoin | Major | |
| Famotidine | Moderate |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir)
- Strong CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin, St. John's wort)
- Antacids and proton pump inhibitors
- Anticoagulants (e.g., warfarin, heparin)
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
⚡ Moderate Interactions
- Grapefruit juice
- H2 blockers (e.g., famotidine, ranitidine)
- NSAIDs (e.g., ibuprofen, naproxen)
🍷 Alcohol Interaction
Alcohol may increase the risk of liver problems and dizziness when taken with this medicine. It is advisable to avoid or limit alcohol consumption while on this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to dasatinib or any component of the formulation","Severe hepatic impairment","Congenital long QT syndrome","Uncontrolled or significant cardiovascular disease","Active bleeding disorders"]
⚠️ Warnings & Precautions
["This medicine can cause severe bleeding. Monitor for signs of bleeding and avoid concomitant use of anticoagulants if possible.","Fluid retention, including pleural effusion and pericardial effusion, can occur. Monitor for weight gain, swelling, and shortness of breath.","QT prolongation can occur. Use with caution in patients with a history of QT prolongation, electrolyte abnormalities, or those taking other QT-prolonging drugs.","Tumor lysis syndrome may occur in patients with rapidly proliferating tumors. Ensure adequate hydration and monitor electrolytes.","This medicine can cause liver damage. Monitor liver function tests regularly.","Pulmonary arterial hypertension has been reported. Monitor for new onset of shortness of breath, fatigue, or chest pain.","This medicine may impair fertility in both men and women. Discuss fertility preservation options before starting treatment.","Avoid live vaccines during treatment."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding is not recommended during treatment and for at least 2 weeks after the last dose.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. In case of suspected overdose, stop the medicine and seek immediate medical attention. Supportive care and monitoring of vital signs, blood counts, and electrolytes are recommended. Gastric lavage may be considered if ingestion is recent. Contact a poison control center for guidance.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
This medicine must only be taken under the supervision of a qualified cancer specialist. Do not start, stop, or change the dose without consulting your doctor. Take the tablet at the same time each day, with or without food, but avoid grapefruit and grapefruit juice as they can increase the level of this medicine in your body. Swallow the tablet whole; do not crush, chew, or break it. If you miss a dose, take it as soon as you remember on the same day, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time. This medicine can cause dizziness or blurred vision; avoid driving or operating heavy machinery until you know how it affects you. Use effective contraception during treatment and for at least 30 days after the last dose if you are a woman of childbearing potential, and for at least 90 days if you are a man with a female partner. Do not breastfeed while taking this medicine. Inform your doctor immediately if you become pregnant or suspect pregnancy. Keep all appointments for blood tests and heart monitoring. Store this medicine at room temperature away from moisture and heat, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially fluid retention, fatigue, and heart rhythm problems. Close monitoring is recommended. Dose adjustments may be needed based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
This medicine may harm the unborn baby. Women of childbearing potential should use effective contraception during treatment and for at least 30 days after the last dose. Men with female partners should use effective contraception during treatment and for at least 90 days after the last dose. If you are planning to become pregnant, consult your doctor before stopping the medicine.
🏥 Post-Surgery Considerations
This medicine can increase the risk of bleeding and impair wound healing. Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. Your doctor may advise you to temporarily stop the medicine before surgery. Follow your doctor's instructions carefully.
🦷 Dental Procedures
This medicine can increase the risk of bleeding during dental procedures. Inform your dentist that you are taking this medicine. Your dentist may recommend postponing non-urgent procedures or taking precautions to control bleeding. Maintain good oral hygiene to prevent dental problems.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe and beneficial, but avoid strenuous activities that could increase the risk of bleeding or injury. If you experience fatigue, shortness of breath, or dizziness, stop and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause fatigue, dizziness, or blurred vision, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. You may need to adjust your work schedule or take time off during treatment. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Stopping suddenly can cause the disease to worsen. Your doctor may decide to stop treatment if the disease progresses, side effects become intolerable, or based on your overall health. Always follow your doctor's guidance.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to persistent side effects such as fatigue, fluid retention, and increased risk of infections. Regular monitoring of blood counts, liver function, and heart health is essential. Some patients may develop pulmonary arterial hypertension or other cardiovascular complications. Fertility may be affected in both men and women. Discuss long-term plans and monitoring with your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines like imatinib, nilotinib, or ponatinib may be used as alternatives based on disease status and tolerability.
Evidence: Well-establishedA potential curative option for some patients with CML or Ph+ ALL, especially those who do not respond to tyrosine kinase inhibitors.
Evidence: Well-establishedParticipation in clinical trials may provide access to new treatments.
Evidence: Varies💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment with this medicine because they can cause serious infections. Inactivated vaccines are generally safe, but their effectiveness may be reduced. Consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature between 20°C and 25°C (68°F to 77°F)
❌ DON'T
Do not refrigerate
✅ DO
Keep in the original container, tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from moisture and heat
❌ DON'T
Do not store in the bathroom
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiration date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and avoid direct sunlight. If crossing time zones, consult your doctor about adjusting the timing of your dose. Check customs regulations for carrying prescription medicines internationally. Always carry enough supply for your entire trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The onset of effect varies. Some patients may see improvements in blood counts within weeks, but full response may take several months. Your doctor will monitor your progress with regular blood tests.
A: Yes, this medicine can be taken with or without food. However, avoid grapefruit and grapefruit juice as they can increase the level of the medicine in your body.
A: If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.
A: This medicine may harm the unborn baby. It is not recommended during pregnancy. Use effective contraception during treatment and for at least 30 days after the last dose. Consult your doctor if you become pregnant.
A: It is not known if this medicine passes into breast milk. Because of the potential for serious side effects in nursing infants, breastfeeding is not recommended during treatment and for at least 2 weeks after the last dose.
🤔 Common Patient Concerns
🔄 Substitutes for daslemia 70 tablet
View AllAlternative brands with exact same active ingredient:
-
dasamyl 70mg tabletMylan Pharmaceuticals Pvt Ltd ₹4,589.00 2% CHEAPER
-
nextki 70mg tabletEmcure Pharmaceuticals Ltd ₹5,000.00 6.8% COSTLIER
-
dasamed 70mg tabletMedicamen Biotech Ltd ₹6,750.00 44.1% COSTLIER
-
dasakast 70mg tabletAprazer Healthcare Pvt Ltd ₹7,968.75 70.2% COSTLIER
-
dasatrue 70mg tabletCipla Ltd ₹8,765.62 87.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure leukemia completely.
Fact: This medicine can control the disease and improve quality of life, but it is not a cure. It helps manage the condition long-term. - Myth: This medicine can be taken without regular blood tests.
Fact: Regular blood tests are essential to monitor the effects and side effects of this medicine. - Myth: This medicine can be stopped once you feel better.
Fact: This medicine should only be stopped under the guidance of your doctor. Stopping suddenly can cause the disease to worsen.
🔄 Alternative Options
Generic Alternatives
- Dasatinib 70 mg tablet
Brand Alternatives
- Beedan 70mg Tablet