Cididap M 10mg/500mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, muscle pain, or extreme fatigue (possible lactic acidosis)
- Nausea, vomiting, abdominal pain, or rapid breathing (possible ketoacidosis)
- Severe dizziness or fainting (possible dehydration or low blood pressure)
- Decreased urine output or swelling in legs (possible kidney problems)
- Blood in urine or painful urination (possible urinary tract infection or bladder cancer)
- Swelling of face, lips, or throat (possible allergic reaction)
- Yellowing of skin or eyes (possible liver problems)
If experiencing severe symptoms, call emergency services immediately.
What is dapatrend m 10mg/500mg tablet used for?
This medicine is a combination of dapagliflozin and metformin used to treat type 2 diabetes. It helps lower blood sugar by increasing glucose excretion in urine and reducing glucose production in the liver. It is taken orally with meals, usually once daily.
- Generic Name: Dapagliflozin + Metformin
- Manufacturer: Anthem Biopharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 dapatrend m 10mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में ब्लड शुगर को कंट्रोल करने में मदद करती है। इसमें डैपाग्लिफ्लोज़िन और मेटफॉर्मिन दो दवाएं होती हैं जो अलग-अलग तरीकों से शुगर को कम करती हैं। यह दवा खाने के साथ लेनी चाहिए और डॉक्टर की सलाह के बिना बंद नहीं करनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में जननांगों में फंगल इन्फेक्शन, यूरिन इन्फेक्शन, जी मिचलाना, दस्त, सिरदर्द और चक्कर आना शामिल हैं। गंभीर साइड इफेक्ट्स में लैक्टिक एसिडोसिस, कीटोएसिडोसिस, डिहाइड्रेशन और किडनी की समस्या हो सकती है। अगर आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे खाने के साथ लें ताकि पेट में जलन न हो। दिनभर पर्याप्त पानी पिएं। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अपने ब्लड शुगर की नियमित जांच कराएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो इस दवा का इस्तेमाल न करें।
💊 dapatrend m 10mg/500mg tablet Uses & Benefits
[{"condition":"Type 2 Diabetes Mellitus","description":"Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when metformin alone or dapagliflozin alone does not provide adequate control.","evidence":"Well-established"},{"condition":"Type 2 Diabetes Mellitus with Cardiovascular Risk","description":"May reduce the risk of cardiovascular death, hospitalization for heart failure, and kidney disease progression in patients with type 2 diabetes and established cardiovascular disease or multiple risk factors.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Heart Failure with Reduced Ejection Fraction (HFrEF)","description":"Dapagliflozin, a component of this medicine, is approved for HFrEF irrespective of diabetes status, but the combination with metformin is not indicated for this use.","evidence":"Well-established for dapagliflozin alone"},{"condition":"Chronic Kidney Disease","description":"Dapagliflozin alone is approved for chronic kidney disease, but the combination product is not indicated for this purpose.","evidence":"Well-established for dapagliflozin alone"}]
Primary treatment for: Type 2 Diabetes Mellitus
Also treats: Cardiovascular disease, Chronic kidney disease, Heart failure
📋 Drug Information
| Generic Name(s) | Dapagliflozin + Metformin |
| Brand Name | Cididap M 10mg/500mg Tablet |
| Manufacturer | Anthem Biopharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | SGLT2 Inhibitor + Biguanide |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends metformin as a first-line treatment for type 2 diabetes. SGLT2 inhibitors, including dapagliflozin, are recommended as second-line or add-on therapy in patients with cardiovascular or renal disease. |
| ICMR Guideline | The Indian Council of Medical Research guidelines recommend metformin as initial therapy for type 2 diabetes. Dapagliflozin may be added for additional glycemic control and cardiovascular/renal benefits. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antidiabetic agents with complementary mechanisms. Dapagliflozin inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules, reducing renal glucose reabsorption and increasing urinary glucose excretion, thereby lowering blood glucose levels independently of insulin. Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Together, they improve glycemic control through different pathways.
Mechanism Steps
💡 How to Take dapatrend m 10mg/500mg tablet
Strength: Tablet containing Dapagliflozin 10 mg and Metformin 500 mg (immediate-release).
Dosage Information
| Adult Dosage | The usual recommended dose is one tablet taken orally once daily with meals. The dose may be adjusted by your doctor based on your blood sugar levels, kidney function, and overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially regarding kidney function and dehydration. Dose should be adjusted based on renal function. Regular monitoring is advised. |
| Renal Impairment | Dapagliflozin: not recommended if eGFR <45 mL/min/1.73 m2 for glycemic control; may be continued for other benefits. Metformin: contraindicated if eGFR <30 mL/min/1.73 m2; dose adjustment needed for eGFR 30-45. Consult your doctor for specific guidance. |
| Hepatic Impairment | Dapagliflozin: no dose adjustment needed for mild to moderate hepatic impairment; not recommended for severe impairment. Metformin: use with caution in hepatic impairment due to risk of lactic acidosis. Consult your doctor. |
| Maximum Daily Dose | Dapagliflozin: 10 mg. Metformin: 2000 mg (immediate-release). The maximum daily dose of this combination is one tablet of 10 mg/500 mg, but your doctor may prescribe additional metformin separately if needed. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of dapatrend m 10mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Iodinated contrast media | Major | |
| Diuretics | Major | |
| Insulin | Moderate | |
| Cationic drugs | Moderate | |
| Nifedipine | Minor | |
| Furosemide | Minor |
🚨 Major Interactions
- Alcohol
- Iodinated contrast media
- Diuretics
⚡ Moderate Interactions
- Insulin or insulin secretagogues
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
🍷 Alcohol Interaction
Alcohol should be avoided or limited while taking this medicine due to an increased risk of lactic acidosis, a rare but serious complication associated with metformin. Alcohol can also cause hypoglycemia and worsen dehydration.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Lactic acidosis: rare but serious; discontinue and seek immediate medical help if suspected.","Ketoacidosis: may occur even with normal blood sugar; report symptoms immediately.","Volume depletion: may cause hypotension; monitor and maintain hydration.","Genital mycotic infections: monitor and treat as needed.","Vitamin B12 deficiency: long-term metformin use may cause; monitor levels.","Hypoglycemia: risk increases when used with insulin or secretagogues.","Surgery: temporarily discontinue before surgery as advised by doctor."]
🤱 Lactation Safety
Not recommended during breastfeeding. It is not known if dapagliflozin is excreted in human milk. Metformin is excreted in human milk in small amounts. Consult your doctor for alternative treatments.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Symptoms may include severe hypoglycemia, lactic acidosis, or dehydration. Treatment is supportive and symptomatic. Hemodialysis may be considered for metformin overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor. Swallow the tablet whole with a glass of water. Take it with meals to reduce stomach upset. Stay well hydrated throughout the day. Avoid excessive alcohol consumption while taking this medicine, as it increases the risk of lactic acidosis. Monitor your blood sugar levels regularly as advised. Inform your doctor if you have kidney or liver problems, or if you are scheduled for surgery or imaging tests. Do not use this medicine if you are pregnant or breastfeeding. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to dehydration, hypotension, and kidney impairment. Regular monitoring of kidney function and blood pressure is advised. Dose adjustments may be necessary based on renal function.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative, such as insulin, before conception.
🏥 Post-Surgery Considerations
This medicine may need to be temporarily discontinued before surgery due to the risk of lactic acidosis and dehydration. Consult your surgeon and doctor for specific instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed for routine dental procedures, but maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is encouraged while taking this medicine, but be cautious about dehydration, especially if you sweat heavily. Drink plenty of water before, during, and after exercise. If you experience dizziness or weakness, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people, especially during the initial days. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it should not significantly impact your daily work life. Maintain regular meal times and take the medicine with food.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as lactic acidosis, ketoacidosis, or severe allergic reactions, seek immediate medical attention and follow your doctor's advice regarding discontinuation.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to vitamin B12 deficiency due to metformin, requiring periodic monitoring. It may also increase the risk of genital infections and, rarely, bladder cancer. Regular monitoring of kidney function, blood sugar, and vitamin B12 levels is recommended. The cardiovascular and renal benefits of dapagliflozin may persist with long-term use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet and exercise are essential for managing type 2 diabetes and can complement medication.
Evidence: Well-establishedDepending on your condition, your doctor may prescribe alternative medications such as sulfonylureas, DPP-4 inhibitors, or insulin.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, patients with diabetes should stay up to date with recommended vaccinations, including influenza and pneumococcal vaccines, as they are at higher risk of infections.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip plus extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but it may take several weeks to see the full effect on blood sugar levels. Regular monitoring is important.
A: It depends on the severity of kidney disease. This medicine is not recommended if your eGFR is below 30 mL/min/1.73 m2. Consult your doctor for personalized advice.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for dapatrend m 10mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
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dgson m 10mg/500mg tabletUnison Healthcare ₹60.75 48.9% CHEAPER
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novidap-m tablet erMetamorf Lifesciences ₹88.13 25.9% CHEAPER
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dapend-10 m tablet erHalberd Pharmaceuticals ₹102.19 14.1% CHEAPER
-
dapashot-m 10/500 tablet erCapitis Healthcare Pvt Ltd ₹102.68 13.7% CHEAPER
-
dapajust m 10mg/500mg tabletErinyle Pharma ₹103.13 13.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar levels but does not cure diabetes. Lifestyle changes and ongoing medical care are essential. - Myth: This medicine causes kidney damage.
Fact: When used appropriately, this medicine can actually protect kidney function in some patients. However, it is not recommended in severe kidney impairment. - Myth: You can stop taking this medicine once your sugar levels are normal.
Fact: Diabetes is a chronic condition. Stopping medication without consulting your doctor can lead to serious complications.
🔄 Alternative Options
Generic Alternatives
- Dapagliflozin + Metformin (generic)
Brand Alternatives
- Cididap M 10mg/500mg Tablet