dapatrend m 10mg/500mg tablet - Dapagliflozin (10mg) + Metformin (500mg) medicine

dapatrend m 10mg/500mg tablet

4.8 (12 reviews)
๐Ÿญ Anthem Biopharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is dapatrend m 10mg/500mg tablet used for?

Cididap M 10mg/500mg Tablet (Dapagliflozin + Metformin) is used to treat ANTI DIABETIC. It contains Dapagliflozin (10mg) + Metformin (500mg), which Dapagliflozin: Inhibits SGLT2 in proximal renal tubules, reducing glucose reabso. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Dapagliflozin + Metformin
  • Manufacturer: Anthem Biopharma
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š dapatrend m 10mg/500mg tablet Uses & Benefits

Type 2 diabetes mellitus as adjunct to diet and exercise; when monotherapy with metformin or dapagliflozin is inadequate

Off-label uses: Type 1 diabetes (dapagliflozin as adjunct; not approved), polycystic ovary syndrome (metformin)

๐Ÿ“‹ Drug Information

Generic Name(s)Dapagliflozin + Metformin
Brand NameCididap M 10mg/500mg Tablet
ManufacturerAnthem Biopharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassSGLT2 Inhibitor + Biguanide
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionDapagliflozin: Rapidly absorbed, Tmax ~2h; Metformin: Absorbed mainly from small intestine, Tmax ~2.5h
DistributionDapagliflozin: Vd ~118 L; Metformin: Vd 654ยฑ358 L, extensively distributed into tissues
Protein BindingDapagliflozin: ~91%; Metformin: Negligible (<5%)
MetabolismDapagliflozin: Primarily via UGT1A9 to inactive metabolites; Metformin: Not metabolized
Half-LifeDapagliflozin: ~12.9h; Metformin: ~6.2h
ExcretionDapagliflozin: 75% urine, 21% feces; Metformin: 90% unchanged in urine
BioavailabilityDapagliflozin: ~78%; Metformin: 50-60%
Onset of ActionDapagliflozin: Within 1h; Metformin: Within 2h
Peak Plasma TimeDapagliflozin: 2h; Metformin: 2.5h
Duration of ActionDapagliflozin: ~24h; Metformin: ~8-12h

How It Works

Dapagliflozin: Inhibits SGLT2 in proximal renal tubules, reducing glucose reabsorption; Metformin: Decreases hepatic glucose production, increases insulin sensitivity

Mechanism Steps

1Dapagliflozin inhibits SGLT2 in proximal renal tubules, reducing glucose reabsorption and increasing urinary glucose excretion.
2Metformin activates AMPK, reducing hepatic gluconeogenesis and increasing peripheral insulin sensitivity.
3Combined effect lowers blood glucose levels independent of insulin secretion.

๐Ÿ’ก How to Take dapatrend m 10mg/500mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of dapatrend m 10mg/500mg tablet

โœ… Common Side Effects

  • Genital mycotic infections
  • Urinary tract infections
  • Nausea
  • Diarrhea
  • Headache
  • Nasopharyngitis

๐Ÿšจ Serious Side Effects

  • Lactic acidosis
  • Diabetic ketoacidosis
  • Acute kidney injury
  • Hypoglycemia
  • Volume depletion
  • Urosepsis

โš ๏ธ Rare Side Effects

  • Fournier's gangrene
  • Pancreatitis
  • Vitamin B12 deficiency (metformin)
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Insulin Major Increased risk of hypoglycemia
Sulfonylureas Major Increased risk of hypoglycemia
Iodinated contrast media Major Increased risk of lactic acidosis (metformin)
Diuretics Moderate Additive volume depletion
ACE inhibitors Moderate Increased risk of hypotension
NSAIDs Moderate Reduced renal function, decreased efficacy
Cimetidine Minor Increased metformin exposure

๐Ÿšจ Major Interactions

  • Insulin
  • Sulfonylureas
  • Meglitinides
  • Contrast media (iodinated)
  • Alcohol abuse

โšก Moderate Interactions

  • Diuretics
  • ACE inhibitors
  • ARBs
  • NSAIDs
  • Corticosteroids
  • Beta-2 agonists

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Furosemide
  • Nifedipine

๐Ÿฝ๏ธ Food Interactions

Metformin: Food decreases absorption; Dapagliflozin: No significant effect

๐Ÿท Alcohol Interaction

Increased risk of lactic acidosis with metformin; acute alcohol intoxication

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Severe renal impairment (eGFR <30), acute or chronic metabolic acidosis, diabetic ketoacidosis, hypersensitivity, severe hepatic impairment, history of lactic acidosis

๐Ÿ“Š Monitoring Parameters

Blood glucose, HbA1c, renal function (eGFR), lactate levels, volume status, blood pressure

๐Ÿคฑ Lactation Safety

Not recommended; dapagliflozin excreted in milk in animal studies; metformin present in human milk

๐Ÿ’Š Overdose Management

Supportive care; monitor glucose, lactate, renal function; hemodialysis may remove metformin

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

๐Ÿ˜Š Was this information helpful?

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