clonithem 100 tablet

4.5 (10 reviews)

Clonidine (100mcg)

🏭 Anthem Biopharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is clonithem 100 tablet used for?

Arkamin (Clonidine) is used to treat CARDIAC. It contains Clonidine (100mcg), which Stimulates alpha-2 adrenergic receptors in the brainstem, reducing sympathetic o. Always consult your doctor before use. Take as prescribed.

Generic Name: Clonidine
Manufacturer: Anthem Biopharma
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 clonithem 100 tablet Uses & Benefits

Hypertension, Attention deficit hyperactivity disorder (ADHD), Opioid withdrawal, Migraine prophylaxis, Menopausal hot flashes

Off-label uses: Tourette syndrome, Post-traumatic stress disorder (PTSD), Diabetic neuropathy, Glaucoma

📋 Drug Information

Generic Name(s)	Clonidine
Brand Name	Arkamin
Manufacturer	Anthem Biopharma
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Alpha 2-adrenoceptors agonist (Central sympatholytics)
Route of Administration	Oral, transdermal patch
Storage	Store at room temperature (20-25°C); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and almost completely absorbed from the gastrointestinal tract.

DistributionWidely distributed throughout the body; crosses blood-brain barrier and placenta.

Protein Binding20-40%

MetabolismHepatic metabolism via CYP2D6; about 50% undergoes first-pass metabolism.

Half-Life12-16 hours (normal renal function); prolonged in renal impairment.

ExcretionRenal (40-60% unchanged); fecal (20%).

Bioavailability75-95% (oral).

Onset of Action30-60 minutes (oral).

Peak Plasma Time2-4 hours (oral).

Duration of Action6-8 hours (oral).

How It Works

Stimulates alpha-2 adrenergic receptors in the brainstem, reducing sympathetic outflow from the CNS.

Mechanism Steps

1Clonidine binds to presynaptic alpha-2 adrenergic receptors in the medulla oblongata.

2Activation of these receptors inhibits adenylate cyclase, reducing cAMP levels.

3Decreased cAMP leads to reduced calcium influx and neurotransmitter release.

💡 How to Take clonithem 100 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of clonithem 100 tablet

✅ Common Side Effects

Dry mouth
Drowsiness
Dizziness
Constipation
Fatigue

🚨 Serious Side Effects

Severe bradycardia
Rebound hypertension (abrupt withdrawal)
Hallucinations
Angioedema

⚠️ Rare Side Effects

Raynaud phenomenon
Parotid gland pain
Gynecomastia
Hepatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

🚨 Major Interactions

Beta-blockers (risk of bradycardia and rebound hypertension)
MAOIs (hypertensive crisis)
Tricyclic antidepressants (reduced antihypertensive effect)

⚡ Moderate Interactions

Antipsychotics (enhanced hypotensive effect)
Calcium channel blockers (additive bradycardia)
Digoxin (bradycardia)
Insulin (masking of hypoglycemia symptoms)

ℹ️ Minor Interactions

Diuretics (additive hypotensive effect)
NSAIDs (reduced antihypertensive effect)

🍽️ Food Interactions

Avoid alcohol; may enhance hypotensive effect.

🍷 Alcohol Interaction

Additive hypotensive effect; avoid.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to clonidine, Severe bradycardia or sick sinus syndrome, Concurrent use with MAOIs

📊 Monitoring Parameters

Blood pressure, Heart rate, Sedation level, Renal function

🤱 Lactation Safety

Low risk; excreted in breast milk in small amounts; monitor infant for hypotension.

💊 Overdose Management

Supportive care; atropine for bradycardia; vasopressors for hypotension; activated charcoal if recent ingestion.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for clonithem 100 tablet

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Alternative brands with exact same active ingredient (Clonidine (100mcg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026