dapaford m forte 10mg/1000mg tablet - Dapagliflozin (10mg) + Metformin (1000mg) medicine

Dapasach M 10mg/1000mg Tablet: Complete Guide

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🏭 Leeford Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or rapid breathing
  • Severe nausea, vomiting, or abdominal pain
  • Unusual muscle pain or weakness
  • Extreme fatigue or dizziness
  • Decreased urine output
  • Signs of genital infection with severe pain or swelling
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is dapaford m forte 10mg/1000mg tablet used for?

This medicine is a combination of dapagliflozin and metformin used to treat type 2 diabetes. It helps control blood sugar by removing excess sugar through urine and reducing sugar production in the liver.

  • Generic Name: Dapagliflozin (10mg) + Metformin (1000mg)
  • Manufacturer: Leeford Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 dapaford m forte 10mg/1000mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा टाइप 2 डायबिटीज के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में ब्लड शुगर को कंट्रोल करने में मदद करती है। यह दवा किडनी के जरिए अतिरिक्त शुगर को यूरिन से बाहर निकालती है और लिवर में शुगर बनने की प्रक्रिया को कम करती है। इसका इस्तेमाल दिल की बीमारी और किडनी की बीमारी वाले मरीजों में भी फायदेमंद हो सकता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में जननांग में फंगल इन्फेक्शन, यूरिन इन्फेक्शन, जी मिचलाना, दस्त, पेट में असहजता और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में डायबिटिक कीटोएसिडोसिस और लैक्टिक एसिडोसिस शामिल हैं। अगर सांस लेने में तकलीफ, तेज दिल की धड़कन, या मांसपेशियों में तेज दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से डोज न बदलें और न ही दवा बंद करें। पर्याप्त पानी पिएं ताकि डिहाइड्रेशन और किडनी की समस्या से बचा जा सके। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अगर आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं तो इस दवा का सेवन न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 dapaford m forte 10mg/1000mg tablet Uses & Benefits

[{"condition":"Type 2 Diabetes Mellitus","description":"Improves blood sugar control in adults when metformin alone or other therapies are insufficient.","evidence":"Well-established"},{"condition":"Heart Failure with Reduced Ejection Fraction","description":"Dapagliflozin component reduces the risk of cardiovascular death and hospitalization for heart failure.","evidence":"Well-established"},{"condition":"Chronic Kidney Disease","description":"Dapagliflozin component slows the progression of kidney disease in patients with or without diabetes.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Weight management in type 2 diabetes","description":"Dapagliflozin may cause modest weight loss, but this is not a primary indication.","evidence":"Limited"},{"condition":"Non-alcoholic fatty liver disease","description":"Some studies suggest benefit, but not an approved use.","evidence":"Limited"}]

Primary treatment for: Type 2 Diabetes Mellitus

Also treats: Heart Failure, Chronic Kidney Disease

📋 Drug Information

Generic Name(s)Dapagliflozin (10mg) + Metformin (1000mg)
Brand Namedapaford m forte 10mg/1000mg tablet
ManufacturerLeeford Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset.
2
Stay well hydrated throughout the day to prevent dehydration.
3
Monitor your blood sugar levels regularly as advised.
4
Maintain good genital hygiene to prevent fungal infections.
5
Avoid excessive alcohol consumption to reduce the risk of lactic acidosis.
6
Inform your doctor if you are scheduled for surgery or contrast imaging.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDapagliflozin is rapidly absorbed after oral administration, reaching peak plasma concentrations within 2 hours. Metformin is slowly absorbed from the small intestine, with peak levels at 2-3 hours. Food does not significantly affect the absorption of either component.
DistributionDapagliflozin is approximately 91% protein-bound and does not distribute extensively into tissues. Metformin is negligibly protein-bound and distributes into various tissues, including the liver, kidney, and gastrointestinal tract.
Protein BindingDapagliflozin: ~91% bound to plasma proteins. Metformin: negligible protein binding.
MetabolismDapagliflozin is primarily metabolized by UGT1A9 to inactive metabolites. Metformin is not metabolized and is excreted unchanged.
Half-LifeDapagliflozin: approximately 12.9 hours. Metformin: approximately 6.2 hours.
ExcretionDapagliflozin is excreted mainly in urine (75%) and feces (21%). Metformin is excreted unchanged in urine (approximately 90%).
BioavailabilityDapagliflozin: approximately 78%. Metformin: approximately 50-60%.
Onset of ActionBlood glucose lowering begins within hours, but full therapeutic effect may take several days to weeks.
Peak Plasma TimeDapagliflozin: 2 hours. Metformin: 2-3 hours.
Duration of ActionDapagliflozin: 24 hours. Metformin: 24 hours with immediate-release formulation taken multiple times daily.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Dapagliflozin inhibits sodium-glucose cotransporter 2 (SGLT2) in the proximal tubules of the kidney, reducing glucose reabsorption and increasing urinary glucose excretion. Metformin decreases hepatic glucose production, reduces intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Mechanism Steps

1
SGLT2 inhibition by dapagliflozin: Dapagliflozin blocks SGLT2 in the kidney, preventing glucose reabsorption and causing glucose to be excreted in urine.
2
Reduced hepatic glucose production by metformin: Metformin decreases glucose production in the liver by inhibiting mitochondrial respiration and activating AMPK.
3
Improved insulin sensitivity: Metformin enhances the body's response to insulin, increasing glucose uptake in muscles and fat.
4
Combined glycemic control: The two mechanisms work together to lower blood sugar levels more effectively than either alone.

💡 How to Take dapaford m forte 10mg/1000mg tablet

Strength: Tablet containing dapagliflozin 10 mg and metformin hydrochloride 1000 mg.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3Take with meals to reduce stomach upset.
4Do not crush, chew, or break the tablet.
5Take at the same time each day for best results.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once daily with meals. The dose may be adjusted by your doctor based on your blood sugar levels, kidney function, and overall health. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dehydration and kidney problems. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.
Renal ImpairmentDapagliflozin dose may need adjustment in moderate renal impairment. Metformin is contraindicated in severe renal impairment (eGFR <30 mL/min/1.73 m²). Consult your doctor for dose adjustments based on your kidney function.
Hepatic ImpairmentUse with caution in patients with liver impairment. Metformin is contraindicated in severe liver disease. Dose adjustment may be necessary.
Maximum Daily DoseThe maximum recommended daily dose is dapagliflozin 10 mg and metformin 1000 mg twice daily, but the exact dose depends on the individual patient's needs and kidney function.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with meals
Reduces stomach upset and improves absorption.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of dapaford m forte 10mg/1000mg tablet

✅ Common Side Effects

Genital fungal infections (Common (5-10%))
Maintain good hygiene. Consult doctor if symptoms persist.
Urinary tract infections (Common (5-10%))
Drink plenty of water. Consult doctor if symptoms worsen.
Nausea (Common (5-10%))
Take with food. Usually resolves over time.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe.

🚨 Serious Side Effects

Diabetic ketoacidosis (Rare (<0.1%))
Seek immediate medical attention if you experience nausea, vomiting, abdominal pain, or difficulty breathing.
Lactic acidosis (Rare (<0.1%))
Seek emergency care if you have rapid breathing, muscle pain, extreme fatigue, or stomach discomfort.
Dehydration and hypotension (Uncommon (0.1-1%))
Drink fluids and consult doctor if you feel dizzy or faint.
Kidney impairment (Uncommon (0.1-1%))
Regular monitoring of kidney function is advised. Report decreased urine output.

⚠️ Rare Side Effects

Necrotizing fasciitis of the perineum
Seek immediate medical attention if you have severe pain, redness, or swelling in the genital area.
Hypersensitivity reactions
Seek emergency care if you develop rash, swelling, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Iodinated contrast media Major
Diuretics Major
Cationic drugs Moderate
Insulin Moderate
Sulfonylureas Moderate
ACE inhibitors Minor

🚨 Major Interactions

  • Alcohol
  • Iodinated contrast media
  • Diuretics

⚡ Moderate Interactions

  • Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
  • Insulin or insulin secretagogues (e.g., sulfonylureas)

🍷 Alcohol Interaction

Avoid excessive alcohol consumption while taking this medicine because it increases the risk of lactic acidosis and may cause dangerous drops in blood sugar.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to dapagliflozin or metformin","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Risk of lactic acidosis with metformin, especially in patients with renal impairment, liver disease, or excessive alcohol use.","Risk of diabetic ketoacidosis with dapagliflozin, even if blood sugar is normal.","Risk of genital fungal infections and urinary tract infections.","May cause dehydration and hypotension; monitor fluid intake.","Temporarily discontinue before surgery or iodinated contrast procedures.","Not recommended during pregnancy or breastfeeding.","May cause vitamin B12 deficiency with long-term use."]

🤱 Lactation Safety

Not recommended during breastfeeding. It is not known if dapagliflozin passes into breast milk. Metformin passes into breast milk in small amounts. Consult your doctor for alternative treatments.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms may include severe hypoglycemia, lactic acidosis, or dehydration. Treatment is supportive and symptomatic. Hemodialysis may be considered for metformin overdose.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Stay well hydrated to help prevent dehydration and kidney problems. Maintain good genital hygiene to reduce the risk of fungal infections. Avoid excessive alcohol consumption because it increases the risk of lactic acidosis. Inform your doctor if you have kidney or liver problems, or if you are scheduled for surgery or a contrast imaging procedure. Do not take this medicine if you are pregnant or planning to become pregnant. Monitor your blood sugar regularly as advised.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of dehydration, kidney problems, and lactic acidosis. Regular monitoring of kidney function and hydration status is advised.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative like insulin.

🏥 Post-Surgery Considerations

This medicine should be temporarily discontinued before surgery and restarted only after your doctor confirms it is safe, usually after 48 hours.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve blood sugar control.
🥗
Engage in regular physical activity like walking or swimming.
😴
Eat a balanced diet rich in fiber and low in processed sugars.
💧
Monitor your blood sugar levels regularly.
🧘
Get adequate sleep to support overall health.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Exercise is beneficial, but monitor blood sugar before and after exercise. Stay hydrated to prevent dehydration. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include whole grains, fruits, and vegetables.
Limit intake of sugary drinks and processed foods.
Choose lean proteins and healthy fats.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it should not significantly impact your daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or are planning pregnancy, contact your doctor immediately for alternative treatment.

📅 Long-Term Use Effects

Long-term use may lead to vitamin B12 deficiency due to metformin. Regular monitoring of kidney function, blood sugar, and vitamin B12 levels is advised. Dapagliflozin may provide long-term cardiovascular and renal benefits.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are essential for managing diabetes.

Evidence: Well-established
Other oral antidiabetic agents

Alternatives include sulfonylureas, DPP-4 inhibitors, or insulin.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any live vaccines.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 52-year-old man with type 2 diabetes and heart failure
Started this medicine as prescribed. Within a few weeks, his blood sugar levels improved, and he felt more energetic. He was advised to drink plenty of water and maintain hygiene. He experienced mild nausea initially, which resolved after taking the medicine with food.
💡 Lesson: Taking the medicine with food and staying hydrated helps manage side effects and improves tolerability.
👤 A 60-year-old woman with type 2 diabetes and chronic kidney disease
Her doctor prescribed this medicine to help control blood sugar and protect her kidneys. She was monitored regularly for kidney function. She did not experience any serious side effects and her kidney function remained stable.
💡 Lesson: Regular monitoring of kidney function is essential for patients with kidney disease taking this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood sugar within hours, but full effects may take several days to weeks.

Q: Can I take this medicine with other diabetes medicines?

A: It may be used with other medicines, but only under your doctor's supervision due to the risk of hypoglycemia.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for dapaford m forte 10mg/1000mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes.
    Fact: This medicine helps manage blood sugar levels but does not cure diabetes.
  • Myth: This medicine causes weight gain.
    Fact: This medicine may cause mild weight loss due to glucose excretion in urine.
  • Myth: You can stop taking this medicine once blood sugar is normal.
    Fact: Diabetes is a chronic condition; stopping medicine without doctor's advice can cause blood sugar to rise again.

🔄 Alternative Options

Generic Alternatives

  • Dapagliflozin + Metformin generic tablets

Brand Alternatives

  • Dapasach M 10mg/1000mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Dapagliflozin + Metformin","class":"SGLT2 inhibitor + Biguanide","key_benefit":"Cardiovascular and renal protection"},{"medicine":"Empagliflozin + Metformin","class":"SGLT2 inhibitor + Biguanide","key_benefit":"Cardiovascular and renal protection"},{"medicine":"Sitagliptin + Metformin","class":"DPP-4 inhibitor + Biguanide","key_benefit":"Weight neutral, low hypoglycemia risk"}]

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