cytopill 35mg tablet sr - Uses, Price, Side Effects & Substitutes
What is cytopill 35mg tablet sr used for?
Accardi MR Tablet MR (Trimetazidine) is used to treat CARDIAC. It contains Trimetazidine (35mg), which Inhibits long-chain 3-ketoacyl-CoA thiolase, shifting myocardial energy metaboli. Always consult your doctor before use. Take as prescribed.
- Generic Name: Trimetazidine
- Manufacturer: Race Pharmaceuticals pvt ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cytopill 35mg tablet sr Uses & Benefits
Adjunctive therapy for stable angina pectoris; also used for vertigo and tinnitus (off-label in some regions).
Off-label uses: Vertigo, Tinnitus, Diabetic cardiomyopathy
๐ Drug Information
| Generic Name(s) | Trimetazidine |
| Brand Name | Accardi MR Tablet MR |
| Manufacturer | Race Pharmaceuticals pvt ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Fatty acid modulator & Sodium channel blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits long-chain 3-ketoacyl-CoA thiolase, shifting myocardial energy metabolism from fatty acid oxidation to glucose oxidation, thereby improving cardiac efficiency under ischemic conditions.
Mechanism Steps
๐ก How to Take cytopill 35mg tablet sr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cytopill 35mg tablet sr
โ Common Side Effects
- Dizziness
- Headache
- Gastrointestinal disturbances (nausea, vomiting, diarrhea)
- Asthenia
๐จ Serious Side Effects
- Parkinsonism
- Tremor
- Gait instability
- Restless leg syndrome
- Severe bradycardia
โ ๏ธ Rare Side Effects
- Allergic reactions (rash, urticaria)
- Hepatitis
- Thrombocytopenia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Paroxetine | Major | Increased trimetazidine plasma concentration due to CYP2D6 inhibition |
| Ketoconazole | Major | Increased trimetazidine plasma concentration due to CYP3A4 inhibition |
| Warfarin | Moderate | Possible increased anticoagulant effect; monitor INR |
| Metoprolol | Moderate | Additive bradycardia and hypotension |
๐จ Major Interactions
- CYP2D6 inhibitors (e.g., paroxetine, fluoxetine)
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
โก Moderate Interactions
- Antihypertensives (additive hypotensive effect)
- Beta-blockers
- Calcium channel blockers
โน๏ธ Minor Interactions
- Antacids
- Food (delayed absorption)
๐ฝ๏ธ Food Interactions
Food may delay absorption but does not significantly affect overall bioavailability.
๐ท Alcohol Interaction
No significant interaction reported; however, alcohol may exacerbate angina symptoms.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to trimetazidine or excipients; Parkinson's disease, parkinsonian symptoms, tremors, restless leg syndrome; severe renal impairment (CrCl <30 mL/min).
๐ Monitoring Parameters
Blood pressure, heart rate, ECG, renal function, liver function tests.
๐คฑ Lactation Safety
Excreted in breast milk; avoid use or discontinue breastfeeding.
๐ Overdose Management
No specific antidote; symptomatic and supportive treatment. Gastric lavage if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless almost time for next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cytopill 35mg tablet sr
View AllAlternative brands with exact same active ingredient (Trimetazidine (35mg)):
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davaindia trimetazidine 35mg tablet mrDavaindia Generic Pharmacy โน30.00 57.1% CHEAPER
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flavezee 35 sr tabletZeelab Pharmacy Pvt Ltd โน35.00 49.9% CHEAPER
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stayhappi trimetazidine 35mg tabletSarvagunaushdhi Pvt Ltd โน39.38 43.7% CHEAPER
-
carzid 35mg tabletDiligence Pharma โน56.25 19.5% CHEAPER
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isvedon 35mg tablet crLife Medicare & Biotech Pvt Ltd โน56.25 19.5% CHEAPER
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minodon 35 xr tabletMinova Life Sciences Pvt Ltd โน65.00 7% CHEAPER
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invidon 35 xr tabletInvision Medi Sciences Pvt Ltd โน65.63 6.1% CHEAPER
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stridon 35mg tablet mrSiochem Pharma Pvt Ltd โน66.56 4.8% CHEAPER
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carvidon-od 35mg tabletMicro Labs Ltd โน69.83 0.1% CHEAPER
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zutrim 35mg tablet srZodley Pharmaceuticals Pvt Ltd โน70.00 0.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.