flavezee 35 sr tablet - Trimetazidine (35mg) medicine

Flavedon MR Tablet (Trimetazidine 35mg): Complete Medicine Guide

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🏭 Zeelab Pharmacy Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for stable angina as add-on therapy.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden severe chest pain that does not respond to your usual angina medicine
  • Tremors, rigidity, or difficulty walking
  • Restless legs or uncontrollable urge to move legs
  • Fainting or severe dizziness
  • Irregular heartbeat or palpitations
  • Signs of allergic reaction: rash, itching, swelling of face, lips, or throat
  • Decreased urine output or swelling in legs

If experiencing severe symptoms, call emergency services immediately.

What is flavezee 35 sr tablet used for?

This medicine contains Trimetazidine 35 mg, used as add-on therapy for stable angina. It improves heart energy metabolism and reduces angina attacks. It is not for immediate relief of acute angina.

  • Generic Name: Trimetazidine (35mg)
  • Manufacturer: Zeelab Pharmacy Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 flavezee 35 sr tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ट्राइमेटाजिडीन 35 मिलीग्राम युक्त है और स्थिर एनजाइना (सीने में दर्द) के इलाज में सहायक दवा के रूप में उपयोग की जाती है। यह हृदय की मांसपेशियों को ऑक्सीजन का बेहतर उपयोग करने में मदद करती है, जिससे एनजाइना के दौरे कम होते हैं। यह दवा तीव्र एनजाइना के दौरे के तत्काल राहत के लिए नहीं है। इसे डॉक्टर के परामर्श के बिना न लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, पेट दर्द, दस्त, अपच, मतली, उल्टी और कमजोरी शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पार्किंसन जैसे लक्षण (कंपन, अकड़न), गिरना, अनियमित दिल की धड़कन और निम्न रक्तचाप शामिल हो सकते हैं। यदि आपको असामान्य मांसपेशियों की हरकत, चलने में कठिनाई या लगातार चक्कर आते हैं तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गोली को चबाएं या तोड़ें नहीं, पूरा निगल लें। यह दवा तीव्र एनजाइना के दौरे के तत्काल इलाज के लिए नहीं है, इसलिए अपनी तेजी से काम करने वाली एनजाइना दवा हमेशा साथ रखें। यदि आपको चक्कर या कमजोरी महसूस हो तो वाहन चलाने या मशीनरी चलाने से बचें। यदि आपको गुर्दे की समस्या, पार्किंसन रोग या कोई मूवमेंट डिसऑर्डर है तो अपने डॉक्टर को बताएं। डॉक्टर की सलाह के बिना दवा बंद न करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 flavezee 35 sr tablet Uses & Benefits

[{"condition":"Stable angina pectoris","description":"Used as add-on therapy for the symptomatic treatment of stable angina in adults who are inadequately controlled by or intolerant to first-line anti-anginal therapies.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Ischemic cardiomyopathy","description":"Sometimes prescribed off-label to improve heart muscle function in patients with ischemic heart disease.","evidence":"Limited"},{"condition":"Vertigo","description":"Occasionally used off-label for vertigo, but evidence is weak.","evidence":"Limited"}]

Primary treatment for: Stable angina pectoris

Also treats: Ischemic heart disease, Coronary artery disease

📋 Drug Information

Generic Name(s)Trimetazidine (35mg)
Brand Nameflavezee 35 sr tablet
ManufacturerZeelab Pharmacy Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassFatty acid modulator & Sodium channel blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset.
2
Do not crush or chew the modified-release tablet; swallow it whole.
3
Keep a fast-acting angina medicine (like nitroglycerin) with you at all times for acute attacks.
4
Inform your doctor if you experience any movement difficulties, tremors, or restless legs.
5
Avoid driving or operating machinery if you feel dizzy after taking this medicine.
6
Do not stop this medicine abruptly without consulting your doctor.
7
Regular follow-up with your doctor is important to monitor kidney function and symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chest pain on exertion
This medicine is commonly prescribed for stable angina.
Likely Use
Acute angina attack
This medicine is not for immediate relief of acute attacks.
Not Primary
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTrimetazidine is rapidly absorbed after oral administration. The modified-release formulation provides a more sustained release of the drug over time. Food does not significantly affect the absorption of this medicine.
DistributionTrimetazidine is widely distributed in the body. It has a volume of distribution of approximately 4.8 L/kg. It crosses the blood-brain barrier and can accumulate in the brain.
Protein BindingTrimetazidine is approximately 16% bound to plasma proteins.
MetabolismTrimetazidine is primarily metabolized in the liver, but the exact metabolic pathways are not fully established from the available information.
Half-LifeThe elimination half-life of Trimetazidine is approximately 7 hours in healthy volunteers and up to 12 hours in elderly patients.
ExcretionTrimetazidine is mainly excreted unchanged in the urine. About 60-80% of an oral dose is excreted in the urine, primarily as unchanged drug.
BioavailabilityThe bioavailability of Trimetazidine after oral administration is approximately 90%.
Onset of ActionThe onset of action for this medicine is not established from the available information, but it is not intended for immediate relief of acute angina attacks.
Peak Plasma TimeThe peak plasma concentration for the modified-release formulation is reached in about 3-5 hours after oral administration.
Duration of ActionThe duration of action for this medicine is not established from the available information, but it is typically taken twice daily to provide continuous symptom control.

How It Works

This medicine works by inhibiting the enzyme long-chain 3-ketoacyl-CoA thiolase, which is involved in fatty acid oxidation in the heart muscle. By blocking this enzyme, it shifts the heart's energy production from fatty acid oxidation to glucose oxidation, which is more oxygen-efficient. This results in better utilization of oxygen by the heart muscle, reducing the demand for oxygen and thereby decreasing the frequency of angina attacks. It does not affect heart rate or blood pressure significantly.

Mechanism Steps

1
Inhibition of fatty acid oxidation: This medicine inhibits long-chain 3-ketoacyl-CoA thiolase, an enzyme involved in fatty acid beta-oxidation in the heart muscle.
2
Shift to glucose oxidation: By inhibiting fatty acid oxidation, the heart muscle shifts to glucose oxidation, which requires less oxygen to produce the same amount of energy.
3
Improved oxygen efficiency: This metabolic shift allows the heart to function more efficiently with the available oxygen, reducing the occurrence of angina attacks.

💡 How to Take flavezee 35 sr tablet

Strength: Modified-release tablet, 35 mg

1Swallow the tablet whole with a glass of water.
2Do not crush, chew, or break the tablet.
3Take with meals to reduce stomach upset.
4Take at the same times each day to maintain consistent levels.
5If you have kidney problems, your doctor may adjust the dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one 35 mg modified-release tablet taken twice daily, preferably with meals. The dose may be adjusted by your doctor based on your kidney function and clinical response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and movement disorders. Dose adjustment may be necessary based on renal function. Close monitoring is recommended.
Renal ImpairmentIn patients with moderate renal impairment (creatinine clearance 30-60 mL/min), the dose should be reduced to one 35 mg tablet once daily. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min).
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 70 mg (two 35 mg tablets) in patients with normal renal function. In moderate renal impairment, the maximum daily dose is 35 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of flavezee 35 sr tablet

✅ Common Side Effects

Dizziness (Common (1-10%))
Avoid driving or operating machinery until you know how this medicine affects you. If dizziness persists, consult your doctor.
Headache (Common (1-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Abdominal pain (Common (1-10%))
Take the medicine with food to reduce stomach discomfort. If pain persists, consult your doctor.
Diarrhea (Common (1-10%))
Stay hydrated. If diarrhea is severe or lasts more than a few days, consult your doctor.
Nausea (Common (1-10%))
Take with food. If nausea is bothersome, consult your doctor.

🚨 Serious Side Effects

Parkinsonian symptoms (tremor, rigidity, bradykinesia) (Rare (<0.1%))
Stop the medicine and seek immediate medical attention. These symptoms usually resolve after discontinuation.
Falls (Rare (<0.1%))
Seek medical attention if you experience a fall, especially if you have dizziness or unsteady gait.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, fainting, or shortness of breath.
Low blood pressure (hypotension) (Rare (<0.1%))
If you feel faint or dizzy, lie down and seek medical help if symptoms persist.

⚠️ Rare Side Effects

Restless legs syndrome
Consult your doctor if you experience an uncontrollable urge to move your legs, especially at night.
Gait instability
Report to your doctor if you have difficulty walking or unsteadiness.
Hallucinations
Seek immediate medical attention if you experience hallucinations.

Consult your doctor if you experience any unusual symptoms.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Trimetazidine or any component of the formulation","Parkinson's disease, Parkinsonian symptoms, tremors, restless legs syndrome","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["This medicine is not for the immediate relief of an acute angina attack. Always keep fast-acting nitrates available.","May cause or worsen Parkinsonian symptoms. Discontinue if such symptoms occur.","Use with caution in elderly patients due to increased risk of falls and movement disorders.","Dose adjustment is required in patients with moderate renal impairment.","Avoid use in patients with severe renal impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Not established from the available information. It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

There is no specific antidote for Trimetazidine overdose. Treatment should be symptomatic and supportive. In case of overdose, seek immediate medical attention. Monitor vital signs and provide supportive care as needed.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not crush or chew the modified-release tablet; swallow it whole with water. This medicine is not for immediate relief of an acute angina attack; always keep your fast-acting angina medicine available. Avoid driving or operating heavy machinery if you feel dizzy or weak after taking this medicine. Inform your doctor if you have kidney problems, Parkinson's disease, or any movement disorder. Do not stop taking this medicine without consulting your doctor, as sudden withdrawal may worsen angina. Regular follow-up with your doctor is important to monitor your condition and adjust treatment if needed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at increased risk of dizziness, falls, and Parkinsonian symptoms. Dose adjustment may be needed based on kidney function. Close monitoring is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily. Follow your doctor's advice.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are established, but it is important for your dentist to know your medical history.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the workload on your heart.
🥗
Engage in regular low-impact exercise like walking or swimming, as advised by your doctor.
😴
Follow a heart-healthy diet low in saturated fats and salt.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep to support heart health.

🏋️ Exercise Considerations

This medicine may cause dizziness or low blood pressure, which can affect your ability to exercise. Start slowly and avoid strenuous activities until you know how the medicine affects you. Always warm up and cool down. If you experience chest pain during exercise, stop and seek medical attention.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits and vegetables.
Limit salt to control blood pressure.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or weakness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It should not affect your ability to perform desk work, but take breaks if you feel dizzy.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like Parkinsonian symptoms, your doctor may advise you to stop. Always follow your doctor's guidance.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well-tolerated. However, it may cause or worsen Parkinsonian symptoms, especially in the elderly. Regular monitoring of kidney function and neurological symptoms is recommended. The medicine should be reviewed periodically to ensure it remains appropriate for your condition.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Heart-healthy diet, exercise, and stress management can complement medicine.

Evidence: Well-established
Other anti-anginal medicines

Beta-blockers, calcium channel blockers, or nitrates may be used.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from direct sunlight. If crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Check local customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 62-year-old man with stable angina despite taking other heart medicines
He was prescribed this medicine as add-on therapy. After a few weeks, he noticed fewer angina attacks during his daily walks. He initially felt dizzy but it subsided after a few days. He emphasizes taking it with breakfast and dinner.
💡 Lesson: This medicine can reduce angina frequency when added to existing therapy. Dizziness is common initially but often improves.
👤 A 70-year-old woman with angina and mild kidney problems
Her doctor adjusted the dose to once daily due to her kidney function. She experienced no side effects and her angina remained well controlled. She stresses the importance of regular kidney function tests.
💡 Lesson: Dose adjustment is crucial in kidney impairment to avoid side effects and ensure safety.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine may take a few weeks to show its full effect in reducing angina attacks. It is not for immediate relief of acute angina.

Q: Can I take this medicine with other heart medicines?

A: Yes, it is often prescribed as add-on therapy with other heart medicines. However, always inform your doctor about all medicines you are taking.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for flavezee 35 sr tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used to relieve an acute angina attack.
    Fact: This medicine is not for immediate relief of acute angina. It is used for long-term management to reduce the frequency of attacks.
  • Myth: This medicine can be taken without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision.
  • Myth: This medicine is safe for everyone with heart disease.
    Fact: It is contraindicated in people with Parkinson's disease, severe kidney problems, and certain other conditions.

🔄 Alternative Options

Generic Alternatives

  • Trimetazidine 35 mg modified-release tablet

Brand Alternatives

  • Flavedon MR Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Trimetazidine","class":"Anti-anginal","mechanism":"Shifts energy metabolism","route":"Oral","common_side_effects":"Dizziness, headache, GI upset"},{"medicine":"Ranolazine","class":"Anti-anginal","mechanism":"Inhibits late sodium current","route":"Oral","common_side_effects":"Dizziness, constipation, nausea"}]

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