Flavedon MR Tablet (Trimetazidine 35mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Sudden severe chest pain that does not respond to your usual angina medicine
- Tremors, rigidity, or difficulty walking
- Restless legs or uncontrollable urge to move legs
- Fainting or severe dizziness
- Irregular heartbeat or palpitations
- Signs of allergic reaction: rash, itching, swelling of face, lips, or throat
- Decreased urine output or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is isvedon 35mg tablet cr used for?
This medicine contains Trimetazidine 35 mg, used as add-on therapy for stable angina. It improves heart energy metabolism and reduces angina attacks. It is not for immediate relief of acute angina.
- Generic Name: Trimetazidine (35mg)
- Manufacturer: Life Medicare & Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 isvedon 35mg tablet cr के बारे में (Hindi Summary)
उपयोग: यह दवा ट्राइमेटाजिडीन 35 मिलीग्राम युक्त है और स्थिर एनजाइना (सीने में दर्द) के इलाज में सहायक दवा के रूप में उपयोग की जाती है। यह हृदय की मांसपेशियों को ऑक्सीजन का बेहतर उपयोग करने में मदद करती है, जिससे एनजाइना के दौरे कम होते हैं। यह दवा तीव्र एनजाइना के दौरे के तत्काल राहत के लिए नहीं है। इसे डॉक्टर के परामर्श के बिना न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, पेट दर्द, दस्त, अपच, मतली, उल्टी और कमजोरी शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पार्किंसन जैसे लक्षण (कंपन, अकड़न), गिरना, अनियमित दिल की धड़कन और निम्न रक्तचाप शामिल हो सकते हैं। यदि आपको असामान्य मांसपेशियों की हरकत, चलने में कठिनाई या लगातार चक्कर आते हैं तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गोली को चबाएं या तोड़ें नहीं, पूरा निगल लें। यह दवा तीव्र एनजाइना के दौरे के तत्काल इलाज के लिए नहीं है, इसलिए अपनी तेजी से काम करने वाली एनजाइना दवा हमेशा साथ रखें। यदि आपको चक्कर या कमजोरी महसूस हो तो वाहन चलाने या मशीनरी चलाने से बचें। यदि आपको गुर्दे की समस्या, पार्किंसन रोग या कोई मूवमेंट डिसऑर्डर है तो अपने डॉक्टर को बताएं। डॉक्टर की सलाह के बिना दवा बंद न करें।
💊 isvedon 35mg tablet cr Uses & Benefits
[{"condition":"Stable angina pectoris","description":"Used as add-on therapy for the symptomatic treatment of stable angina in adults who are inadequately controlled by or intolerant to first-line anti-anginal therapies.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Ischemic cardiomyopathy","description":"Sometimes prescribed off-label to improve heart muscle function in patients with ischemic heart disease.","evidence":"Limited"},{"condition":"Vertigo","description":"Occasionally used off-label for vertigo, but evidence is weak.","evidence":"Limited"}]
Primary treatment for: Stable angina pectoris
Also treats: Ischemic heart disease, Coronary artery disease
📋 Drug Information
| Generic Name(s) | Trimetazidine (35mg) |
| Brand Name | isvedon 35mg tablet cr |
| Manufacturer | Life Medicare & Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Fatty acid modulator & Sodium channel blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting the enzyme long-chain 3-ketoacyl-CoA thiolase, which is involved in fatty acid oxidation in the heart muscle. By blocking this enzyme, it shifts the heart's energy production from fatty acid oxidation to glucose oxidation, which is more oxygen-efficient. This results in better utilization of oxygen by the heart muscle, reducing the demand for oxygen and thereby decreasing the frequency of angina attacks. It does not affect heart rate or blood pressure significantly.
Mechanism Steps
💡 How to Take isvedon 35mg tablet cr
Strength: Modified-release tablet, 35 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 35 mg modified-release tablet taken twice daily, preferably with meals. The dose may be adjusted by your doctor based on your kidney function and clinical response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and movement disorders. Dose adjustment may be necessary based on renal function. Close monitoring is recommended. |
| Renal Impairment | In patients with moderate renal impairment (creatinine clearance 30-60 mL/min), the dose should be reduced to one 35 mg tablet once daily. This medicine is contraindicated in severe renal impairment (creatinine clearance <30 mL/min). |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 70 mg (two 35 mg tablets) in patients with normal renal function. In moderate renal impairment, the maximum daily dose is 35 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of isvedon 35mg tablet cr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Trimetazidine or any component of the formulation","Parkinson's disease, Parkinsonian symptoms, tremors, restless legs syndrome","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine is not for the immediate relief of an acute angina attack. Always keep fast-acting nitrates available.","May cause or worsen Parkinsonian symptoms. Discontinue if such symptoms occur.","Use with caution in elderly patients due to increased risk of falls and movement disorders.","Dose adjustment is required in patients with moderate renal impairment.","Avoid use in patients with severe renal impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Not established from the available information. It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
There is no specific antidote for Trimetazidine overdose. Treatment should be symptomatic and supportive. In case of overdose, seek immediate medical attention. Monitor vital signs and provide supportive care as needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush or chew the modified-release tablet; swallow it whole with water. This medicine is not for immediate relief of an acute angina attack; always keep your fast-acting angina medicine available. Avoid driving or operating heavy machinery if you feel dizzy or weak after taking this medicine. Inform your doctor if you have kidney problems, Parkinson's disease, or any movement disorder. Do not stop taking this medicine without consulting your doctor, as sudden withdrawal may worsen angina. Regular follow-up with your doctor is important to monitor your condition and adjust treatment if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at increased risk of dizziness, falls, and Parkinsonian symptoms. Dose adjustment may be needed based on kidney function. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily. Follow your doctor's advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are established, but it is important for your dentist to know your medical history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or low blood pressure, which can affect your ability to exercise. Start slowly and avoid strenuous activities until you know how the medicine affects you. Always warm up and cool down. If you experience chest pain during exercise, stop and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or weakness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It should not affect your ability to perform desk work, but take breaks if you feel dizzy.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like Parkinsonian symptoms, your doctor may advise you to stop. Always follow your doctor's guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well-tolerated. However, it may cause or worsen Parkinsonian symptoms, especially in the elderly. Regular monitoring of kidney function and neurological symptoms is recommended. The medicine should be reviewed periodically to ensure it remains appropriate for your condition.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Heart-healthy diet, exercise, and stress management can complement medicine.
Evidence: Well-establishedBeta-blockers, calcium channel blockers, or nitrates may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from direct sunlight. If crossing time zones, continue taking your doses at the same intervals as prescribed; consult your doctor for specific advice. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take a few weeks to show its full effect in reducing angina attacks. It is not for immediate relief of acute angina.
A: Yes, it is often prescribed as add-on therapy with other heart medicines. However, always inform your doctor about all medicines you are taking.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for isvedon 35mg tablet cr
View AllAlternative brands with exact same active ingredient:
-
davaindia trimetazidine 35mg tablet mrDavaindia Generic Pharmacy ₹30.00 46.7% CHEAPER
-
flavezee 35 sr tabletZeelab Pharmacy Pvt Ltd ₹35.00 37.8% CHEAPER
-
stayhappi trimetazidine 35mg tabletSarvagunaushdhi Pvt Ltd ₹39.38 30% CHEAPER
-
carzid 35mg tabletDiligence Pharma ₹56.25 SAME PRICE
-
minodon 35 xr tabletMinova Life Sciences Pvt Ltd ₹65.00 15.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used to relieve an acute angina attack.
Fact: This medicine is not for immediate relief of acute angina. It is used for long-term management to reduce the frequency of attacks. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision. - Myth: This medicine is safe for everyone with heart disease.
Fact: It is contraindicated in people with Parkinson's disease, severe kidney problems, and certain other conditions.
🔄 Alternative Options
Generic Alternatives
- Trimetazidine 35 mg modified-release tablet
Brand Alternatives
- Flavedon MR Tablet