cyprotone 500 mg/600 mg syrup - Ciprofloxacin (500mg) + Tinidazole (600mg) medicine

cyprotone 500 mg/600 mg syrup

No reviews yet
🏭 Magnum Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is cyprotone 500 mg/600 mg syrup used for?

This medicine contains Ciprofloxacin (500mg) + Tinidazole (600mg) and is used to treat GASTRO INTESTINAL. Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Tinidazole disrupts DNA structure . Always consult your doctor before use.

  • Generic Name: Ciprofloxacin + Tinidazole
  • Manufacturer: Magnum Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 cyprotone 500 mg/600 mg syrup Uses & Benefits

Infectious diarrhea, dysentery, intra-abdominal infections, gynecologic infections, and mixed infections caused by susceptible bacteria and protozoa.

Off-label uses: Prophylaxis in travelers' diarrhea, treatment of Helicobacter pylori (with other agents).

📋 Drug Information

Generic Name(s)Ciprofloxacin + Tinidazole
Brand NameAlcipro TN 500 mg/600 mg Tablet
ManufacturerMagnum Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAntibiotic + Antiprotozoal
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCiprofloxacin: Rapidly absorbed from GI tract; Tinidazole: Well absorbed orally.
DistributionCiprofloxacin: Widely distributed to tissues and fluids; Tinidazole: Distributed to most tissues and crosses blood-brain barrier.
Protein BindingCiprofloxacin: 20-40%; Tinidazole: 12%.
MetabolismCiprofloxacin: Partially hepatic (CYP1A2); Tinidazole: Hepatic via oxidation.
Half-LifeCiprofloxacin: 4 hours; Tinidazole: 12-14 hours.
ExcretionCiprofloxacin: Renal (50-70% unchanged); Tinidazole: Renal (25%) and fecal.
BioavailabilityCiprofloxacin: 70-80%; Tinidazole: >90%.
Onset of ActionCiprofloxacin: 1-2 hours; Tinidazole: 1 hour.
Peak Plasma TimeCiprofloxacin: 1-2 hours; Tinidazole: 2 hours.
Duration of ActionCiprofloxacin: 12 hours; Tinidazole: 24 hours.

How It Works

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Tinidazole disrupts DNA structure in protozoa and anaerobic bacteria.

Mechanism Steps

1Ciprofloxacin enters bacterial cell via porins.
2Binds to DNA gyrase and topoisomerase IV, inhibiting DNA supercoiling and replication.
3Bactericidal effect due to DNA fragmentation.
4Tinidazole enters anaerobic cells via diffusion.
5Nitro group reduced to toxic radicals that damage DNA.
6DNA strand breakage and cell death.

💡 How to Take cyprotone 500 mg/600 mg syrup

Follow your doctor's prescription exactly.

⚠️ Side Effects of cyprotone 500 mg/600 mg syrup

✅ Common Side Effects

Nausea
Diarrhea
Headache
Dizziness
Metallic taste
Vomiting

🚨 Serious Side Effects

Tendon rupture
Peripheral neuropathy
CNS effects (seizures, confusion)
QT prolongation
Clostridioides difficile colitis
Severe hypersensitivity

⚠️ Rare Side Effects

Hemolytic anemia
Stevens-Johnson syndrome
Hepatotoxicity
Nephritis
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Theophylline Major Increased theophylline toxicity
Tizanidine Major Severe hypotension and sedation
NSAIDs Major Increased CNS stimulation and seizure risk
Oral hypoglycemics Major Hypoglycemia
Cyclosporine Moderate Increased nephrotoxicity
Methotrexate Moderate Increased methotrexate toxicity
Phenytoin Moderate Altered phenytoin levels
Probenecid Moderate Increased ciprofloxacin levels
Ropinirole Moderate Increased ropinirole levels
Caffeine Minor Increased caffeine effects
Duloxetine Minor Possible increased duloxetine levels
Metformin Minor Possible lactic acidosis risk
Omeprazole Minor Reduced ciprofloxacin absorption

🚨 Major Interactions

  • Warfarin
  • Theophylline
  • Tizanidine
  • NSAIDs
  • Oral hypoglycemics

⚡ Moderate Interactions

  • Cyclosporine
  • Methotrexate
  • Phenytoin
  • Probenecid
  • Ropinirole

🍷 Alcohol Interaction

Avoid alcohol during and for 3 days after tinidazole due to disulfiram-like reaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to quinolones or nitroimidazoles; history of tendon disorders with quinolones; pregnancy (first trimester for tinidazole); lactation; children

🤱 Lactation Safety

Ciprofloxacin: Excreted in milk, avoid; Tinidazole: Excreted in milk, avoid.

💊 Overdose Management

Supportive care; monitor ECG, renal function; dialysis may help remove ciprofloxacin.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

🔄 Substitutes for cyprotone 500 mg/600 mg syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory