anacold syrup - Cetirizine (2.5mg/5ml) + Paracetamol (125mg/5ml) medicine

Alkem Cold Suspension: Complete Medicine Guide

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🏭 Magnum Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe abdominal pain or yellowing of eyes/skin
  • Blood in vomit or stool
  • Unusual bleeding or bruising
  • Severe drowsiness or confusion
  • Persistent fever for more than 3 days
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is anacold syrup used for?

This medicine is a combination of cetirizine (antihistamine) and paracetamol (pain reliever and fever reducer) used to treat symptoms of common cold and allergies such as runny nose, sneezing, and mild fever.

  • Generic Name: Cetirizine + Paracetamol
  • Manufacturer: Magnum Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 anacold syrup के बारे में (Hindi Summary)

उपयोग: यह दवा सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आँखों में पानी आना, खुजली और हल्के बुखार या दर्द से राहत दिलाने के लिए इस्तेमाल की जाती है। इसमें सेटिरिज़िन और पैरासिटामोल दोनों होते हैं, जो मिलकर लक्षणों को कम करते हैं।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, थकान और हल्का पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लिवर की समस्या या खून की बीमारी हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा की मात्रा न बढ़ाएँ। पैरासिटामोल वाली अन्य दवाओं के साथ न लें। शराब न पिएँ। नींद आ सकती है, इसलिए वाहन न चलाएँ। लिवर या किडनी की बीमारी में सावधानी बरतें। डॉक्टर की सलाह के बिना लंबे समय तक न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 anacold syrup Uses & Benefits

[{"condition":"Common cold","description":"Relieves runny nose, sneezing, watery eyes, and mild fever associated with common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, nasal itching, rhinorrhea, and ocular symptoms.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps relieve itching and hives.","evidence":"Well-established"},{"condition":"Mild pain and fever","description":"Paracetamol component reduces mild to moderate pain and fever.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold and allergic rhinitis

Also treats: Urticaria, Mild pain and fever

📋 Drug Information

Generic Name(s)Cetirizine + Paracetamol
Brand NameAlerid Cold Tablet
ManufacturerMagnum Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Shake the bottle well before each use to ensure uniform mixing of the suspension.
2
Use the provided measuring cup or spoon to measure the dose accurately; household spoons are not reliable.
3
Avoid giving this medicine to children under 2 years without a doctor's advice.
4
Do not use this medicine for more than 7 days without consulting a doctor.
5
If you are taking other medications, check with your doctor or pharmacist for interactions.
6
Store the bottle in a cool, dry place and keep it out of reach of children.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Runny nose
This medicine is commonly used for this symptom.
Likely Use
Sneezing
This medicine helps relieve sneezing.
Likely Use
Mild fever
Paracetamol component reduces fever.
Likely Use
Severe headache
This medicine is not intended for severe headache; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCetirizine is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1 hour. Paracetamol is also rapidly absorbed from the gastrointestinal tract, with peak plasma levels occurring within 0.5 to 2 hours.
DistributionCetirizine is widely distributed throughout the body, including the skin. Paracetamol distributes rapidly into most body tissues except fat.
Protein BindingCetirizine is about 93% bound to plasma proteins. Paracetamol is only minimally bound to plasma proteins (about 10-25%).
MetabolismCetirizine undergoes minimal hepatic metabolism. Paracetamol is metabolized primarily in the liver via glucuronidation and sulfation, with a small fraction metabolized by cytochrome P450 2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeCetirizine elimination half-life is approximately 8-10 hours in adults. Paracetamol half-life is about 2-3 hours.
ExcretionCetirizine is excreted primarily unchanged in the urine. Paracetamol metabolites are excreted in the urine.
BioavailabilityCetirizine oral bioavailability is high (approximately 70% or more). Paracetamol oral bioavailability is about 80-100%.
Onset of ActionCetirizine onset of action is within 1 hour. Paracetamol onset of action is within 30-60 minutes.
Peak Plasma TimeCetirizine peak plasma time is about 1 hour. Paracetamol peak plasma time is 0.5-2 hours.
Duration of ActionCetirizine duration of action is about 24 hours. Paracetamol duration of action is 4-6 hours.

How It Works

Cetirizine is a selective peripheral H1-receptor antagonist. It inhibits the early phase of allergic reactions by blocking histamine release from mast cells and basophils. Paracetamol acts primarily in the central nervous system to produce analgesia and antipyresis, possibly by inhibiting prostaglandin synthesis in the brain.

Mechanism Steps

1
Histamine H1 receptor blockade: Cetirizine binds to H1 receptors on effector cells, preventing histamine from triggering allergic responses like vasodilation, increased vascular permeability, and sensory nerve stimulation.
2
Central prostaglandin inhibition: Paracetamol inhibits prostaglandin synthesis in the central nervous system, which elevates the pain threshold and lowers fever.
3
Symptom relief: The combined actions reduce runny nose, sneezing, itching, fever, and mild pain associated with colds and allergies.

💡 How to Take anacold syrup

Strength: Each 5 ml contains cetirizine 2.5 mg and paracetamol 125 mg.

1Shake the bottle well before use.
2Use the measuring cup or spoon provided to measure the correct dose.
3Take orally, with or without food.
4Follow the prescribed schedule.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 5-10 ml of the suspension every 4-6 hours as needed, not to exceed 4 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor.
Maximum Daily DoseFor adults: maximum 4 doses (20 ml) in 24 hours. Do not exceed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect the absorption or efficacy.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of anacold syrup

✅ Common Side Effects

Drowsiness (Common (up to 10%))
Avoid driving or operating machinery. Usually resolves with continued use.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if persistent.
Fatigue (Common (5-10%))
Rest if needed. Consult doctor if severe or persistent.
Nausea (Uncommon (1-5%))
Take with food. Consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling of face/throat, difficulty breathing.
Liver damage (Rare (<0.1%) with normal doses)
Seek medical help if you notice yellowing of eyes or skin, dark urine, or severe abdominal pain.
Blood disorders (e.g., thrombocytopenia) (Very rare (<0.01%))
Report unusual bleeding or bruising to your doctor immediately.

⚠️ Rare Side Effects

Seizures
Seek emergency medical care.
Severe skin reactions (e.g., Stevens-Johnson syndrome)
Stop medicine and seek immediate medical attention if rash with blisters or peeling skin occurs.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other paracetamol products Major
CNS depressants Moderate
Anticholinergics Moderate
Alcohol Major

🚨 Major Interactions

  • Other paracetamol-containing products
  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • CNS depressants (e.g., sedatives, tranquilizers)
  • Anticholinergics

🍷 Alcohol Interaction

Avoid alcohol consumption while taking this medicine. Alcohol increases the risk of liver damage from paracetamol and may enhance drowsiness caused by cetirizine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to cetirizine, paracetamol, or any component","Severe liver impairment","Severe kidney impairment (requires medical supervision)"]

⚠️ Warnings & Precautions

["Do not exceed recommended dose.","Avoid other paracetamol-containing products.","May cause drowsiness; avoid driving.","Avoid alcohol.","Use with caution in liver or kidney disease.","Consult doctor if symptoms persist beyond 7 days."]

🤱 Lactation Safety

Cetirizine and paracetamol are excreted in breast milk in small amounts. Consult a doctor before use during breastfeeding.

💊 Overdose Management

Overdose of paracetamol can cause severe liver damage. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include activated charcoal, N-acetylcysteine, and supportive care. Cetirizine overdose may cause drowsiness, agitation, or tachycardia; manage symptomatically.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not exceed the recommended dose of this medicine. Avoid using other products containing paracetamol while taking this medicine to prevent accidental overdose. Avoid alcohol consumption as it may increase the risk of liver damage and enhance drowsiness. This medicine may cause drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Use with caution in patients with liver or kidney disease, and in the elderly. Do not use for longer than directed without consulting a doctor. Keep out of reach of children. If symptoms persist or worsen, consult a healthcare professional.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and anticholinergic effects. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy has not been fully established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental issues. It may also interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Avoid exposure to allergens like dust and pollen.
💧
Use a humidifier to ease nasal congestion.
🧘
Wash your hands frequently to prevent spreading infections.

🏋️ Exercise Considerations

This medicine may cause drowsiness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Drink warm fluids like soup and tea.
Include vitamin C-rich foods like oranges and lemons.
Avoid cold drinks and ice cream.
Eat light, easily digestible meals.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take it when you can rest.

🛑 When to Stop This Medicine

Stop taking this medicine and consult a doctor if your symptoms persist beyond 7 days, worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver damage, especially at high doses. Cetirizine may cause tolerance or persistent drowsiness. Regular monitoring of liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal spray

Helps relieve nasal congestion without medication.

Evidence: Well-established
Steam inhalation

Can ease nasal congestion and soothe irritated airways.

Evidence: Commonly used

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription if traveling internationally. Store at room temperature and protect from direct sunlight. No time zone adjustments are needed for this medicine as it is taken as needed. Check customs regulations for carrying medications across borders.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with seasonal allergies and mild fever
She was prescribed this medicine for her runny nose, sneezing, and low-grade fever. She took it as directed and noticed significant relief within a day. She experienced mild drowsiness but it subsided after a few doses.
💡 Lesson: This medicine effectively relieves both allergy symptoms and fever when taken as prescribed.
👤 A 45-year-old man with common cold and body ache
He used this medicine for his cold symptoms and body pain. He reported that his symptoms improved, but he felt sleepy, so he avoided driving. He was advised not to take additional paracetamol.
💡 Lesson: Drowsiness is a common side effect; avoid driving and do not exceed the dose.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Cetirizine starts working within 1 hour, and paracetamol within 30-60 minutes. You may feel relief from symptoms within an hour.

Q: Can I take this medicine on an empty stomach?

A: Yes, it can be taken with or without food. However, if you experience stomach upset, take it with food.

Q: Is it safe to take this medicine with other cold medicines?

A: Avoid taking other medicines containing paracetamol or antihistamines without consulting a doctor, as it may lead to overdose or increased side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for anacold syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take extra doses for faster relief.
    Fact: Taking more than the recommended dose can lead to serious side effects, especially liver damage from paracetamol.

🔄 Alternative Options

Generic Alternatives

  • Cetirizine + Paracetamol suspension (generic)

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cetirizine 2.5mg/5ml + Paracetamol 125mg/5ml","uses":"Cold and allergy symptoms with mild fever","notes":"Combination product"},{"medicine":"Cetirizine alone","composition":"Cetirizine","uses":"Allergy symptoms only","notes":"No fever relief"},{"medicine":"Paracetamol alone","composition":"Paracetamol","uses":"Fever and pain only","notes":"No allergy relief"}]

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