cyclonim 10mg/100mg tablet
What is cyclonim 10mg/100mg tablet used for?
Avospas 20mg/100mg Tablet (Dicyclomine + Nimesulide) is used to treat GASTRO INTESTINAL. It contains Dicyclomine (10mg) + Nimesulide (100mg), which Dicyclomine: Antimuscarinic; Nimesulide: COX-2 selective inhibition. Always consult your doctor before use. Take as prescribed.
- Generic Name: Dicyclomine + Nimesulide
- Manufacturer: Pharmatech Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cyclonim 10mg/100mg tablet Uses & Benefits
Irritable bowel syndrome, dysmenorrhea, gastrointestinal spasms
Off-label uses: Not well established
๐ Drug Information
| Generic Name(s) | Dicyclomine + Nimesulide |
| Brand Name | Avospas 20mg/100mg Tablet |
| Manufacturer | Pharmatech Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protected from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Dicyclomine: Antimuscarinic; Nimesulide: COX-2 selective inhibition
Mechanism Steps
๐ก How to Take cyclonim 10mg/100mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cyclonim 10mg/100mg tablet
โ Common Side Effects
- Dry mouth
- Dizziness
- Drowsiness
- Nausea
- Diarrhea
- Abdominal pain
๐จ Serious Side Effects
- GI bleeding
- Hepatotoxicity
- Renal failure
- Anaphylaxis
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Pancreatitis
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| Aspirin | Major | Increased GI ulcer risk |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect |
| Corticosteroids | Moderate | Increased GI ulcer risk |
| SSRIs | Moderate | Increased bleeding risk |
| Antacids | Minor | Reduced absorption of nimesulide |
| Cimetidine | Minor | Increased nimesulide levels |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- Anticoagulants
- Aspirin
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Corticosteroids
- SSRIs
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
Avoid high-fat meals; may delay absorption
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active GI bleeding, severe hepatic/renal impairment, pregnancy (third trimester), history of asthma, children <12 years
๐ Monitoring Parameters
Liver function tests, renal function, GI symptoms, blood pressure
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Gastric lavage, activated charcoal, symptomatic treatment
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double