Akme Clobetacon-GM Skin Cream: Complete Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling, dizziness, trouble breathing.
- Signs of adrenal suppression: extreme tiredness, weakness, nausea, weight loss.
- Severe skin thinning or stretch marks.
- Worsening of infection: increased redness, swelling, pus, or pain.
- Blurred vision or eye pain.
- Symptoms of high blood sugar: increased thirst, frequent urination, confusion.
If experiencing severe symptoms, call emergency services immediately.
What is cutiplain 4 cream used for?
This medicine is a topical cream combining chlorhexidine (an antiseptic) and clobetasol (a strong steroid) to treat inflamed skin conditions with bacterial infection. It should be used short-term and only as prescribed.
- Generic Name: Chlorhexidine Gluconate + Clobetasol Propionate
- Manufacturer: Curever Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cutiplain 4 cream के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल क्रीम है जिसमें क्लोरहेक्सिडिन ग्लूकोनेट और क्लोबेटासोल होते हैं। यह सूजन, खुजली और बैक्टीरियल संक्रमण वाली त्वचा की समस्याओं के इलाज के लिए इस्तेमाल की जाती है। इसे डॉक्टर की सलाह के अनुसार ही लगाएं।
साइड इफेक्ट्स: आम दुष्प्रभावों में जलन, खुजली, सूखापन और लालिमा शामिल हैं। लंबे समय तक उपयोग से त्वचा पतली हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं। कोई भी असामान्य लक्षण होने पर डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस क्रीम को केवल प्रभावित हिस्से पर पतली परत में लगाएं। आंखों, मुंह और श्लेष्मा झिल्ली से बचें। बिना डॉक्टर की सलाह के चेहरे पर न लगाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें। बच्चों की पहुंच से दूर रखें।
💊 cutiplain 4 cream Uses & Benefits
[{"condition":"Eczema with secondary bacterial infection","description":"Helps reduce inflammation and itching while controlling bacterial growth on the skin.","evidence":"Well-established for short-term use"},{"condition":"Psoriasis with secondary infection","description":"Reduces plaques and itching, and prevents infection in affected areas.","evidence":"Well-established for short-term use"},{"condition":"Contact dermatitis with infection","description":"Soothes inflammation and treats bacterial contamination.","evidence":"Well-established for short-term use"},{"condition":"Seborrheic dermatitis with infection","description":"Controls flaking and itching, and reduces bacterial overgrowth.","evidence":"Limited evidence, used in practice"}]
Off-label uses: [{"condition":"Lichen simplex chronicus","description":"Sometimes used to reduce thickening and itching in localized areas.","evidence":"Limited"},{"condition":"Discoid lupus erythematosus","description":"May be used short-term for localized lesions.","evidence":"Limited"}]
Primary treatment for: Inflammatory skin conditions with secondary bacterial infection
Also treats: Eczema, Psoriasis, Contact dermatitis, Seborrheic dermatitis
📋 Drug Information
| Generic Name(s) | Chlorhexidine Gluconate + Clobetasol Propionate |
| Brand Name | Akme Clobetacon-GM Skin Cream |
| Manufacturer | Curever Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Corticosteroid + Antiseptic |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Chlorhexidine gluconate disrupts bacterial cell membranes, leading to leakage of cellular contents and bacterial death. Clobetasol, a super-potent corticosteroid, binds to glucocorticoid receptors in the skin, reducing the production of inflammatory chemicals and suppressing immune responses. Together, they reduce inflammation, itching, and bacterial load on the skin.
Mechanism Steps
💡 How to Take cutiplain 4 cream
Strength: Cream containing chlorhexidine gluconate 0.2% w/w and clobetasol 0.05% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer to the affected area once or twice daily, or as directed by your doctor. The duration of treatment should be limited to 2 weeks unless otherwise prescribed. Dose must be individualized by a qualified clinician based on the condition, severity, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects. Use with caution and for the shortest duration possible. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is required for topical use. Consult your doctor if you have severe kidney disease. |
| Hepatic Impairment | No specific dose adjustment is required for topical use. Consult your doctor if you have severe liver disease. |
| Maximum Daily Dose | Not established from the available information. Use only as prescribed by your doctor. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cutiplain 4 cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole (topical) | Moderate | |
| Ritonavir | Major | |
| Furosemide | Moderate | |
| Insulin | Moderate | |
| Warfarin | Minor |
🚨 Major Interactions
- Other topical corticosteroids
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Antidiabetics
🍷 Alcohol Interaction
No known direct interaction with alcohol when used topically. However, alcohol may worsen certain skin conditions. Consult your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to chlorhexidine, clobetasol, or any ingredient","Untreated bacterial, fungal, or viral skin infections","Acne rosacea","Perioral dermatitis","Use on the face, groin, or underarms unless directed by a doctor","Children under 12 years (unless specifically prescribed)"]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, ears, and mucous membranes.","Do not use on open wounds or broken skin.","Do not cover with airtight dressings unless instructed.","Do not use for longer than prescribed, as it can cause skin thinning and other side effects.","If you are pregnant or breastfeeding, consult your doctor before use.","Keep out of reach of children.","Do not use on the face unless specifically directed by a doctor."]
🤱 Lactation Safety
It is not known if clobetasol or chlorhexidine pass into breast milk in significant amounts after topical use. Consult your doctor before use. Do not apply to the breast area before breastfeeding.
💊 Overdose Management
Overdose is unlikely with topical use. If swallowed, seek immediate medical attention. If applied to large areas for a long time, systemic effects may occur; consult a doctor.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply a thin layer to the affected area only, and rub it in gently. Do not cover with airtight dressings unless told to do so. Avoid contact with eyes, mouth, and other mucous membranes. Wash your hands before and after applying, unless your hands are the treated area. Do not use on large areas or for longer than prescribed. Keep away from children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Do not use on the face unless specifically instructed, as it can cause skin thinning and other problems.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as skin thinning. Use the lowest effective dose for the shortest duration possible.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning pregnancy. Use only if clearly needed and prescribed.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine on surgical wounds. It should not be applied to open wounds unless specifically directed.
🦷 Dental Procedures
No specific considerations for dental procedures. However, inform your dentist if you are using this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions. However, avoid excessive sweating on the treated area immediately after application. If you exercise, gently clean the area and reapply if needed as per your doctor's advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied to the skin and is unlikely to affect your ability to work or drive. However, if you experience any dizziness or unusual symptoms, avoid driving or operating machinery until you feel better.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your condition worsens, if you develop signs of an allergic reaction, or if you notice skin thinning or stretch marks. Do not stop abruptly if you have been using it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to skin thinning, stretch marks, and increased risk of systemic side effects such as adrenal suppression. It should only be used for short periods unless otherwise directed by a doctor. Regular monitoring by a dermatologist is recommended if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help soothe and protect the skin.
Evidence: Well-establishedMay help reduce itching.
Evidence: Well-establishedFor certain chronic skin conditions, under medical supervision.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interaction with vaccines. However, if you have a skin infection, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case you need to show it at customs. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue applying as prescribed; no time adjustment is needed for topical use.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice improvement in itching and redness within a few days. Full effect may take up to a week.
A: No, this cream is not for acne and may worsen it. It is for specific inflammatory skin conditions with infection.
A: No, unless specifically directed by your doctor. It can cause skin thinning and other side effects on the face.
A: Apply it as soon as you remember, but if it is almost time for your next dose, skip the missed dose. Do not double dose.
A: Consult your doctor before use. Do not apply to the breast area before breastfeeding.
🤔 Common Patient Concerns
🔄 Substitutes for cutiplain 4 cream
View AllAlternative brands with exact same active ingredient:
-
dikart 4 creamCure Tech Skincare ₹62.00 27.1% CHEAPER
-
akme clobetacon-gm skin creamAkme Biotec ₹67.97 20% CHEAPER
-
dermalarc 4 creamWynclark Pharmaceuticals Private Limited ₹86.25 1.5% COSTLIER
-
intaderm plus creamIntas Pharmaceuticals Ltd ₹93.00 9.4% COSTLIER
-
curatika four creamTruecure Healthcare Private Limited ₹97.50 14.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This cream can be used for any skin problem.
Fact: It is only for specific inflammatory conditions with infection, and should be used as prescribed. - Myth: More cream means faster healing.
Fact: Using more than prescribed can increase side effects without improving results. - Myth: It is safe to use on the face.
Fact: It should not be used on the face unless specifically directed by a doctor, as it can cause skin thinning.
🔄 Alternative Options
Generic Alternatives
- Chlorhexidine + Clobetasol cream (generic)
Brand Alternatives
- Akme Clobetacon-GM Skin Cream