cutiplain 4 cream
What is cutiplain 4 cream used for?
Akme Clobetacon-GM Skin Cream (Chlorhexidine Gluconate + Clobetasol Propionate) is used to treat DERMA. It contains Chlorhexidine Gluconate (0.2% w/w) + Clobetasol (0.05% w/w), which Clobetasol: Binds to glucocorticoid receptors, inhibiting phospholipase A2, redu. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlorhexidine Gluconate + Clobetasol Propionate
- Manufacturer: Curever Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cutiplain 4 cream Uses & Benefits
Eczema, psoriasis, dermatitis, allergic reactions, bacterial skin infections
Off-label uses: Lichen planus, discoid lupus erythematosus
๐ Drug Information
| Generic Name(s) | Chlorhexidine Gluconate + Clobetasol Propionate |
| Brand Name | Akme Clobetacon-GM Skin Cream |
| Manufacturer | Curever Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Corticosteroid + Antiseptic |
| Route of Administration | Topical |
| Storage | Store at room temperature (20-25ยฐC), away from moisture and heat |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clobetasol: Binds to glucocorticoid receptors, inhibiting phospholipase A2, reducing prostaglandin and leukotriene synthesis; Chlorhexidine: Disrupts microbial cell membranes
Mechanism Steps
๐ก How to Take cutiplain 4 cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cutiplain 4 cream
โ Common Side Effects
- Skin burning
- itching
- irritation
- dryness
- folliculitis
๐จ Serious Side Effects
- Adrenal suppression
- Cushing's syndrome
- skin atrophy
- secondary infection
โ ๏ธ Rare Side Effects
- Allergic contact dermatitis
- hypertrichosis
- pigmentation changes
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased systemic clobetasol levels due to CYP3A4 inhibition |
| Warfarin | Moderate | Possible enhanced anticoagulant effect if significant systemic absorption |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Other topical corticosteroids
โก Moderate Interactions
- Anticoagulants (e.g., warfarin) - systemic absorption may enhance effect
- Antidiabetic agents - may increase blood glucose
โน๏ธ Minor Interactions
- None significant
๐ฝ๏ธ Food Interactions
None known
๐ท Alcohol Interaction
No known interaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, untreated bacterial/fungal/viral infections, rosacea, perioral dermatitis
๐ Monitoring Parameters
Skin condition, signs of infection, adrenal suppression with prolonged use
๐คฑ Lactation Safety
Use with caution; avoid application to breast area
๐ Overdose Management
Excessive topical use may cause systemic corticosteroid effects; treat symptomatically
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
This medicine was effective for me. I followed the doctor's advice.