Codistar-DX Cough Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of the face, lips, tongue, or throat
- Severe dizziness or fainting
- Fast, irregular, or pounding heartbeat
- Seizures or convulsions
- Hallucinations or confusion
- Severe rash or itching
If experiencing severe symptoms, call emergency services immediately.
What is coffingo-cd syrup used for?
This medicine is a combination of chlorpheniramine (an antihistamine) and dextromethorphan (a cough suppressant) used to treat dry cough and allergy symptoms. It works by blocking histamine and suppressing the cough reflex in the brain. It is for short-term use and may cause drowsiness.
- Generic Name: Chlorpheniramine Maleate + Dextromethorphan Hydrobromide
- Manufacturer: Curever Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coffingo-cd syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सूखी खांसी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना और आंखों में पानी आना के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन मेलिएट और डेक्सट्रोमेथोर्फन हाइड्रोब्रोमाइड दो सक्रिय तत्व हैं। क्लोरफेनिरामाइन एक एंटीहिस्टामिन है जो एलर्जी को कम करता है, और डेक्सट्रोमेथोर्फन एक खांसी दबाने वाली दवा है जो दिमाग में खांसी के केंद्र पर काम करती है। यह दवा केवल अल्पकालिक उपयोग के लिए है और इसका उपयोग डॉक्टर की सलाह के अनुसार ही करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, जी मिचलाना, कब्ज और पेशाब करने में कठिनाई शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज बुखार, दाने, सूजन, सांस लेने में तकलीफ, दौरे और हृदय गति में अनियमितता शामिल हो सकती है। अगर आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, खासकर अगर आपको अस्थमा, ग्लूकोमा, प्रोस्टेट की समस्या, हृदय रोग, या लीवर/किडनी की बीमारी है। यह दवा नींद और चक्कर का कारण बन सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। इस दवा के साथ शराब का सेवन न करें। 12 साल से कम उम्र के बच्चों को बिना डॉक्टर की सलाह के यह दवा न दें। गर्भवती और स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।
💊 coffingo-cd syrup Uses & Benefits
[{"condition":"Dry cough","description":"This medicine is used to provide temporary relief from dry, irritating, and unproductive coughs.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"The antihistamine component helps relieve runny nose, sneezing, and watery eyes associated with allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"This medicine may help relieve cough and nasal symptoms associated with the common cold.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cough in interstitial lung disease","description":"Sometimes prescribed off-label to manage chronic dry cough in conditions like interstitial lung disease, but only under specialist supervision.","evidence":"Limited"}]
Primary treatment for: Dry cough
Also treats: Allergic rhinitis, Common cold
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Dextromethorphan Hydrobromide |
| Brand Name | Alex Junior Syrup |
| Manufacturer | Curever Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Antitussive |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains two active ingredients with different mechanisms. Chlorpheniramine maleate is a first-generation antihistamine that works by blocking histamine H1 receptors, thereby reducing allergic symptoms such as runny nose, sneezing, and itching. Dextromethorphan hydrobromide is a centrally acting cough suppressant that acts on the cough center in the medulla oblongata to raise the threshold for coughing. It is a non-opioid agent that does not cause addiction or respiratory depression at therapeutic doses.
Mechanism Steps
💡 How to Take coffingo-cd syrup
Strength: Each 5 ml of syrup contains 4 mg chlorpheniramine maleate and 10 mg dextromethorphan hydrobromide.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 ml (2 teaspoons) every 4 to 6 hours, not to exceed 60 ml in 24 hours. However, the dose may vary depending on the severity of the cough and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. This medicine is for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 12 years of age unless directed by a doctor. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, confusion, and anticholinergic effects. Use with caution and consider dose reduction. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be necessary in patients with renal impairment. Consult a doctor for appropriate dosing. |
| Hepatic Impairment | Dose adjustment may be necessary in patients with hepatic impairment. Consult a doctor for appropriate dosing. |
| Maximum Daily Dose | For adults: 60 ml in 24 hours. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coffingo-cd syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| CNS depressants | Major | |
| CYP2D6 inhibitors | Moderate | |
| Anticholinergics | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to drive or operate machinery. It can also increase the risk of other side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, dextromethorphan, or any component of the formulation.","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOI therapy.","Patients with chronic cough associated with excessive phlegm or chronic bronchitis.","Children under 12 years of age (unless directed by a doctor).","Patients with severe liver disease or severe kidney disease."]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how this medicine affects you.","Avoid alcohol and other CNS depressants.","Do not use for chronic cough or cough with excessive phlegm unless directed by a doctor.","Use with caution in patients with asthma, glaucoma, difficulty urinating, or heart disease.","Do not exceed the recommended dose.","Consult a doctor if cough persists for more than 7 days, or if it is accompanied by fever, rash, or persistent headache.","Keep out of reach of children.","Elderly patients may be more sensitive to the side effects, especially drowsiness and confusion."]
🤱 Lactation Safety
Chlorpheniramine and dextromethorphan are excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, nausea, vomiting, blurred vision, hallucinations, seizures, and respiratory depression. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have a history of asthma, chronic bronchitis, emphysema, or any other breathing problems. Also, tell your doctor if you have glaucoma, difficulty urinating due to an enlarged prostate, thyroid problems, heart disease, high blood pressure, or liver or kidney disease. This medicine may cause drowsiness and impair your ability to drive or operate machinery. Avoid alcoholic beverages while taking this medicine, as alcohol can increase drowsiness and other side effects. Do not take this medicine for a chronic cough that persists for more than 7 days, or for a cough accompanied by excessive phlegm, unless directed by a doctor. Do not use this medicine in children under 12 years of age without medical advice. Pregnant and breastfeeding women should consult their doctor before using this medicine. Keep this medicine out of reach of children. Do not exceed the recommended dose. If your cough does not improve within 7 days or if you develop a fever, rash, or persistent headache, stop taking this medicine and consult your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, confusion, and anticholinergic effects such as dry mouth, constipation, and urinary retention. Use with caution and consider a lower dose. Consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Use only if clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
This medicine may cause drowsiness and respiratory depression, which can be dangerous after surgery. Inform your surgeon and anesthesiologist if you are taking this medicine. It may need to be stopped before surgery.
🦷 Dental Procedures
This medicine may cause dry mouth, which can increase the risk of dental problems. Inform your dentist if you are taking this medicine. It may also interact with medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness, which can impair your ability to exercise safely. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and impair concentration, which may affect your ability to work, drive, or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. If your job requires alertness, discuss with your doctor about timing the dose or alternative options.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, if it is accompanied by fever, rash, or persistent headache, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of chlorpheniramine can lead to tolerance, dependence, and cognitive impairment. Dextromethorphan can cause dependence and withdrawal symptoms with prolonged high-dose use. Regular monitoring by a doctor is advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Warm fluids, honey, and steam inhalation can help soothe a dry cough.
Evidence: LimitedCan help relieve nasal congestion and runny nose.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, continue taking the medicine as prescribed, but adjust the timing gradually to the new time zone. Check the customs regulations of your destination regarding carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The cough suppressant effect usually starts within 15-30 minutes, and the antihistamine effect within 30-60 minutes.
A: You should avoid taking other cough and cold medicines without consulting your doctor, as they may contain similar ingredients and increase the risk of side effects.
A: This medicine is not recommended for children under 12 years of age unless directed by a doctor. Consult a pediatrician for appropriate dosing.
A: Yes, drowsiness is a common side effect. Avoid driving or operating machinery until you know how this medicine affects you.
🤔 Common Patient Concerns
🔄 Substitutes for coffingo-cd syrup
View AllAlternative brands with exact same active ingredient:
-
presil plus syrupKentreck Laboratories Pvt Ltd ₹38.00 59.5% CHEAPER
-
cc go syrupIntas Pharmaceuticals Ltd ₹42.00 55.2% CHEAPER
-
Toxolite DX SyrupLitaka Pharmaceuticals Ltd ₹43.31 53.8% CHEAPER
-
nt kuf syrupHauz Pharma Pvt Ltd ₹45.00 52% CHEAPER
-
coricuff d syrupFervent Life Sciences Pvt Ltd ₹49.22 47.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for dry cough. It is not effective for productive cough with phlegm and may be harmful. - Myth: It is safe to take this medicine for a long time.
Fact: This medicine is for short-term use only. Prolonged use can lead to side effects and dependence. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol increases drowsiness and other side effects. Avoid alcohol.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine + Dextromethorphan syrup (various manufacturers)
Brand Alternatives
- Codistar-DX Cough Syrup