curio 4mg/500mg tablet - Lornoxicam (4mg) + Paracetamol (500mg) medicine

curio 4mg/500mg tablet

4.4 (13 reviews)
๐Ÿญ Dewcare Concept Pvt.Ltd. ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is curio 4mg/500mg tablet used for?

Altra P 4mg/325mg Tablet (Lornoxicam + Paracetamol) is used to treat PAIN ANALGESICS. It contains Lornoxicam (4mg) + Paracetamol (500mg), which Lornoxicam inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetam. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Lornoxicam + Paracetamol
  • Manufacturer: Dewcare Concept Pvt.Ltd.
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š curio 4mg/500mg tablet Uses & Benefits

Acute pain, osteoarthritis, rheumatoid arthritis, dental pain, dysmenorrhea.

Off-label uses: Migraine, postoperative pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Lornoxicam + Paracetamol
Brand NameAltra P 4mg/325mg Tablet
ManufacturerDewcare Concept Pvt.Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionLornoxicam: Well absorbed orally; Paracetamol: Rapidly and completely absorbed from GI tract.
DistributionLornoxicam: Highly bound to plasma proteins; Paracetamol: Widely distributed throughout body fluids.
Protein BindingLornoxicam: >99%; Paracetamol: 10-25%.
MetabolismLornoxicam: Hepatic via CYP2C9; Paracetamol: Hepatic via conjugation (glucuronidation, sulfation) and CYP450 (minor).
Half-LifeLornoxicam: 3-5 hours; Paracetamol: 1.5-3 hours.
ExcretionLornoxicam: Urine (metabolites) and feces; Paracetamol: Urine (metabolites).
BioavailabilityLornoxicam: 90-100%; Paracetamol: 75-85%.
Onset of ActionLornoxicam: 30-60 minutes; Paracetamol: 30-60 minutes.
Peak Plasma TimeLornoxicam: 1-2 hours; Paracetamol: 0.5-1 hour.
Duration of ActionLornoxicam: 8-12 hours; Paracetamol: 4-6 hours.

How It Works

Lornoxicam inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Paracetamol inhibits COX in the CNS, reducing pain and fever.

Mechanism Steps

1Lornoxicam inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis from arachidonic acid.
2Decreased prostaglandins lead to reduced inflammation, pain, and fever.
3Paracetamol inhibits COX in the central nervous system, reducing pain and fever.

๐Ÿ’ก How to Take curio 4mg/500mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of curio 4mg/500mg tablet

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Dizziness
  • Headache
  • Somnolence

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Blood dyscrasias
  • Anaphylaxis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Methotrexate Major Increased methotrexate toxicity
Lithium Major Increased lithium levels
Aspirin Major Increased GI ulceration risk
Other NSAIDs Major Additive GI and renal toxicity
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Anticoagulants Moderate Increased bleeding risk
Corticosteroids Moderate Increased GI ulceration risk
Antacids Minor Reduced absorption of lornoxicam
Cholestyramine Minor Reduced absorption of lornoxicam

๐Ÿšจ Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • Aspirin
  • Other NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Cholestyramine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of lornoxicam; paracetamol absorption unaffected.

๐Ÿท Alcohol Interaction

Increased risk of hepatotoxicity with chronic alcohol use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe hepatic/renal impairment, third trimester pregnancy, history of asthma with NSAIDs.

๐Ÿ“Š Monitoring Parameters

Liver function, renal function, blood pressure, signs of GI bleeding.

๐Ÿคฑ Lactation Safety

Lornoxicam: Not recommended; Paracetamol: Safe in usual doses.

๐Ÿ’Š Overdose Management

Paracetamol: N-acetylcysteine; Lornoxicam: supportive care, activated charcoal.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory