curio 4mg/500mg tablet - Lornoxicam (4mg) + Paracetamol (500mg) medicine

Campar 4mg/500mg Tablet: Complete Medicine Guide

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🏭 Dewcare Concept Pvt.Ltd. 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Use during pregnancy should be based on a careful risk-benefit assessment by a qualified clinician. Avoid use during the third trimester due to risk of premature closure of ductus arteriosus and other complications. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term use in acute pain.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising
  • Severe skin rash or blisters
  • Persistent nausea or vomiting

If experiencing severe symptoms, call emergency services immediately.

What is curio 4mg/500mg tablet used for?

This medicine is a combination of lornoxicam (an NSAID) and paracetamol (an analgesic) used for short-term relief of acute pain and inflammation. It works by reducing prostaglandins that cause pain and swelling. Take it with food to avoid stomach upset and do not exceed the prescribed dose.

  • Generic Name: Lornoxicam + Paracetamol
  • Manufacturer: Dewcare Concept Pvt.Ltd.
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 curio 4mg/500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लॉर्नोक्सिकैम और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द और सूजन के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, ऑपरेशन के बाद के दर्द, और गठिया जैसी स्थितियों में राहत देती है। इसे भोजन के साथ लें ताकि पेट में जलन न हो। इसका उपयोग डॉक्टर की सलाह के बिना 7 दिनों से अधिक न करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति, गंभीर एलर्जी प्रतिक्रिया, और हृदय संबंधी घटनाएं शामिल हो सकती हैं। यदि आपको काला या खूनी मल, खून की उल्टी, गंभीर पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, आंखों या त्वचा का पीलापन, या पेशाब में कमी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। अन्य NSAIDs या पैरासिटामोल युक्त उत्पादों को एक साथ न लें। यदि आपको पेट के अल्सर, गुर्दे या यकृत की बीमारी, हृदय रोग, या अस्थमा का इतिहास है, तो अपने डॉक्टर को बताएं। बुजुर्गों में सावधानी बरतें। गर्भावस्था के तीसरे तिमाही में इसका उपयोग न करें। स्तनपान कराने से पहले डॉक्टर से सलाह लें। इसे कमरे के तापमान पर नमी और गर्मी से दूर रखें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 curio 4mg/500mg tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from moderate to severe dental pain, including post-extraction pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain following surgical procedures.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces pain and improves joint mobility in osteoarthritis of knee, hip, and hand.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps manage pain and inflammation associated with rheumatoid arthritis.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but not a first-line option.","evidence":"Limited"}]

Primary treatment for: Acute pain and inflammation

Also treats: Osteoarthritis, Rheumatoid arthritis, Dental pain, Post-operative pain, Musculoskeletal pain

📋 Drug Information

Generic Name(s)Lornoxicam + Paracetamol
Brand NameAltra P 4mg/325mg Tablet
ManufacturerDewcare Concept Pvt.Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Do not exceed the prescribed dose or duration of treatment.
3
Avoid alcohol while taking this medicine to prevent gastrointestinal bleeding.
4
Do not take other NSAIDs or paracetamol-containing products simultaneously.
5
Consult your doctor if pain persists beyond 7 days or worsens.
6
Report any unusual bleeding, bruising, or dark stools immediately.
7
Stay well hydrated throughout the day to support kidney function.
8
Use the lowest effective dose for the shortest duration possible.
9
Inform your doctor if you have a history of stomach ulcers, kidney, or liver disease.
10
Do not drive or operate machinery if you experience dizziness or drowsiness.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acute musculoskeletal pain
This medicine is commonly prescribed for this.
Likely Use
✅
Dental pain
This medicine is effective for dental pain.
Likely Use
❌
Fever
This medicine is not a primary fever reducer, though paracetamol has antipyretic effects.
Not Primary
❌
Chronic pain
Not for long-term use without medical supervision.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLornoxicam is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly absorbed from the gastrointestinal tract. Food may slightly delay the absorption of both components.
DistributionLornoxicam is highly bound to plasma proteins and distributes into synovial fluid. Paracetamol distributes widely into most body tissues, with relatively low protein binding.
Protein BindingLornoxicam is approximately 99% bound to plasma proteins, primarily albumin. Paracetamol is approximately 10-25% bound to plasma proteins.
MetabolismLornoxicam is extensively metabolized in the liver, primarily by cytochrome P450 enzyme CYP2C9, to inactive metabolites. Paracetamol is metabolized in the liver via glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of lornoxicam is approximately 3-4 hours. The elimination half-life of paracetamol is approximately 2-3 hours.
ExcretionLornoxicam is excreted primarily in the urine and feces as metabolites. Paracetamol is excreted in the urine as glucuronide and sulfate conjugates.
BioavailabilityThe oral bioavailability of lornoxicam is approximately 90-100%. The oral bioavailability of paracetamol is approximately 80-90%.
Onset of ActionOnset of analgesic effect for lornoxicam is within 30-60 minutes. Paracetamol onset is within 30-60 minutes.
Peak Plasma TimePeak plasma concentration of lornoxicam is reached in about 1-2 hours. Peak plasma concentration of paracetamol is reached in about 0.5-2 hours.
Duration of ActionThe duration of analgesic effect for lornoxicam is approximately 8-12 hours. Paracetamol duration is approximately 4-6 hours.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Lornoxicam is a non-steroidal anti-inflammatory drug that inhibits both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased production of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis. Together, they provide enhanced pain relief through different pathways.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Lornoxicam reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: Decreased prostaglandin production leads to reduced inflammation, pain, and fever.
3
Central analgesic action of paracetamol: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain perception.
4
Combined analgesic effect: The dual mechanism provides additive or synergistic pain relief compared to either agent alone.

💡 How to Take curio 4mg/500mg tablet

Strength: Tablet containing lornoxicam 4 mg and paracetamol 500 mg.

1Take the tablet orally with a full glass of water.
2Take with food or milk to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Do not exceed the prescribed dose or duration.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally one to two times daily, or as directed by your doctor. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with food or milk to reduce stomach upset. The maximum duration of use without medical advice is typically 7 days.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and kidney effects. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing. Avoid use in severe kidney impairment.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Avoid use in severe liver impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum daily dose is 2 tablets (lornoxicam 8 mg and paracetamol 1000 mg) per day, unless otherwise prescribed by a doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver damage.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of curio 4mg/500mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If persistent, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated. Consult doctor if severe or persistent.
Stomach pain (Common (5-10%))
Take with food. Avoid alcohol. Consult doctor if severe.
Indigestion (Common (5-10%))
Take with food. Avoid spicy foods. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves. Consult doctor if severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid driving or operating machinery. Consult doctor if persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Seek immediate medical attention if you experience severe stomach pain, heartburn, or nausea.
Kidney problems (Rare (<0.1%))
Seek immediate medical attention if you notice decreased urine output, swelling, or fatigue.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, or throat, difficulty breathing, or rash.
Cardiovascular events (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, shortness of breath, or weakness.

⚠️ Rare Side Effects

Blood disorders
Consult doctor if you notice unusual bleeding, bruising, or infections.
Pancreatitis
Seek immediate medical attention if you experience severe abdominal pain radiating to back.
Severe skin reactions
Seek immediate medical attention if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
ACE inhibitors Major
Diuretics Moderate
Lithium Moderate
SSRIs Moderate
Antacids Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs
  • Corticosteroids
  • Methotrexate
  • ACE inhibitors

⚡ Moderate Interactions

  • Diuretics
  • Lithium
  • SSRIs
  • Anticoagulants (e.g., heparin)

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage. It may also increase drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to lornoxicam, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Active peptic ulcer or history of recurrent peptic ulcer.","Severe liver impairment.","Severe kidney impairment.","Severe heart failure.","Third trimester of pregnancy.","Children under 18 years of age (safety and efficacy not established)."]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration.","Use with caution in the elderly.","Use with caution in patients with a history of gastrointestinal bleeding or ulcer.","Use with caution in patients with kidney or liver disease.","Use with caution in patients with cardiovascular disease or risk factors.","Do not use concurrently with other NSAIDs or paracetamol-containing products.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not drive or operate machinery if you experience dizziness or drowsiness."]

🤱 Lactation Safety

Lornoxicam and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use if you are breastfeeding. Short-term use may be considered if clinically necessary, but monitor the infant for any adverse effects.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, abdominal pain, drowsiness, and liver damage (from paracetamol). Seek immediate medical attention. Treatment includes gastric lavage, activated charcoal, and administration of acetylcysteine for paracetamol toxicity. Monitor liver and kidney function. There is no specific antidote for lornoxicam; supportive care is provided.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it increases the risk of gastrointestinal bleeding. Do not take other NSAIDs or paracetamol-containing products simultaneously. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart disease, or asthma. Use with caution in the elderly. Do not use during the third trimester of pregnancy. Consult your doctor before use if you are breastfeeding. Store at room temperature away from moisture and heat. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution at the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy, especially in the third trimester, due to risks to the fetus.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but consult your surgeon before taking it, as it may increase bleeding risk and interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. It can also be used for dental pain, but follow your dentist's advice.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture and ergonomics.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep to aid recovery.
🌞
Stay well hydrated.
🚭
Avoid smoking and limit alcohol intake.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that may increase pain while taking this medicine. Gentle stretching and low-impact activities are generally safe. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed and fried food intake.
Eat plenty of fruits and vegetables.
Stay well hydrated.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Generally, it does not significantly impact daily activities if taken as prescribed.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, severe abdominal pain, allergic reactions, or if your pain does not improve within 7 days. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulceration, kidney impairment, liver damage, and cardiovascular events. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended. Use the lowest effective dose for the shortest duration. Consult your doctor for periodic reassessment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Heat and cold therapy

May help reduce pain and inflammation locally.

Evidence: Limited
Acupuncture

Some evidence for pain relief in certain conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture and heat. If crossing time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines. Carry enough supply for your trip and keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with acute dental pain
Took this medicine after a tooth extraction. Experienced relief within 45 minutes. She was advised to avoid alcohol and not to exceed the dose. She reported mild drowsiness but no other side effects.
💡 Lesson: This medicine provides rapid relief for acute dental pain when taken as directed. Avoid alcohol and driving if drowsy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce the risk of stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as it may increase the risk of side effects.

Q: Can I take it during pregnancy?

A: Consult your doctor before use. It is not recommended during the third trimester of pregnancy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for curio 4mg/500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: This medicine is intended for short-term use only. Long-term use requires medical supervision due to risks of gastrointestinal, kidney, and cardiovascular side effects.
  • Myth: It is safe to take extra doses if pain is severe.
    Fact: Taking more than the prescribed dose can lead to serious liver damage (from paracetamol) and increased risk of bleeding and kidney problems. Always follow the prescribed dose.
  • Myth: This medicine is safe to take with other painkillers.
    Fact: Combining with other NSAIDs or paracetamol-containing products can increase the risk of side effects. Always consult a doctor before combining.

🔄 Alternative Options

Generic Alternatives

  • Lornoxicam 4 mg + Paracetamol 500 mg tablet (various manufacturers)

Brand Alternatives

  • Campar 4mg/500mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Lornoxicam + Paracetamol","class":"NSAID + Analgesic","onset":"30-60 minutes","duration":"8-12 hours","common_side_effects":"Nausea, stomach pain, dizziness"},{"medicine":"Aceclofenac + Paracetamol","class":"NSAID + Analgesic","onset":"30-60 minutes","duration":"8-12 hours","common_side_effects":"Nausea, stomach pain, headache"},{"medicine":"Diclofenac + Paracetamol","class":"NSAID + Analgesic","onset":"30-60 minutes","duration":"6-8 hours","common_side_effects":"Nausea, stomach pain, dizziness"}]

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