Crusimol Injection: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe abdominal pain or yellowing of skin or eyes
- Decreased urine output or swelling in legs
- Unusual bleeding or bruising
- Severe rash with blisters or peeling skin
- Persistent vomiting or nausea
If experiencing severe symptoms, call emergency services immediately.
What is crusimol injection used for?
This medicine is an injectable form of Paracetamol used to treat pain and fever when oral administration is not possible. It works by reducing fever and pain through central inhibition of prostaglandin synthesis. It is administered by a healthcare professional and should not be self-administered.
- Generic Name: Paracetamol
- Manufacturer: Himanshu Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 crusimol injection के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल का इंजेक्शन है, जिसका उपयोग दर्द और बुखार को कम करने के लिए किया जाता है। यह उन रोगियों के लिए उपयोगी है जो मुंह से दवा नहीं ले सकते या जिन्हें तेजी से राहत की आवश्यकता होती है। यह दवा अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा दी जाती है। इसे स्वयं न लगाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन शामिल हो सकते हैं। कुछ रोगियों को मतली, उल्टी या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, लीवर की समस्या या खून से संबंधित विकार हो सकते हैं। कोई भी गंभीर लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। अगर आपको लीवर या किडनी की बीमारी है, शराब का सेवन करते हैं या कुपोषण है, तो डॉक्टर को बताएं। इस दवा के साथ अन्य पैरासिटामोल युक्त दवाएं न लें। शराब का सेवन न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। एलर्जी के लक्षण दिखने पर तुरंत डॉक्टर को बताएं।
💊 crusimol injection Uses & Benefits
[{"condition":"Mild to moderate pain","description":"This medicine is used to relieve pain when oral administration is not possible or when rapid relief is needed.","evidence":"Well-established"},{"condition":"Fever","description":"It is effective in reducing fever in patients who cannot take oral medications.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used as part of multimodal analgesia to manage pain after surgery.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, though evidence is limited.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Post-operative pain, Migraine, Cancer pain
📋 Drug Information
| Generic Name(s) | Paracetamol |
| Brand Name | Action or 1000mg Tablet |
| Manufacturer | Himanshu Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Analgesic & Antipyretic-PCM |
| Route of Administration | Parenteral (intravenous) |
| Storage | Store below 25°C, protected from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Paracetamol is included in the WHO Model List of Essential Medicines for the treatment of pain and fever. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paracetamol, the active ingredient in this medicine, produces analgesia and antipyresis primarily through central inhibition of prostaglandin synthesis. It acts on the hypothalamus to lower fever and on the central nervous system to reduce pain perception. Unlike nonsteroidal anti-inflammatory drugs, it has minimal anti-inflammatory effects and does not significantly inhibit cyclooxygenase in peripheral tissues. The exact mechanism is not fully understood but is believed to involve inhibition of a central cyclooxygenase variant and modulation of descending serotonergic pathways.
Mechanism Steps
💡 How to Take crusimol injection
Strength: Paracetamol 75 mg/ml injection
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the patient's condition, weight, and renal and hepatic function. For adults, a common dose is 1 gram (1000 mg) every 6 hours as needed, with a maximum of 4 grams in 24 hours. For patients with risk factors for hepatotoxicity, the maximum daily dose may be reduced. The injection should be administered slowly over 15 minutes. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment based on renal and hepatic function. Use with caution and monitor for side effects. |
| Renal Impairment | In patients with severe renal impairment (creatinine clearance less than 30 mL/min), the dosing interval should be increased. Consult a clinician for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, the dose should be reduced or the dosing interval increased. Avoid use in severe liver disease. |
| Maximum Daily Dose | The maximum daily dose for adults is 4 grams (4000 mg) in 24 hours. For patients with risk factors, the maximum may be lower. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of crusimol injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Rifampicin | Moderate |
🚨 Major Interactions
- Warfarin
- Alcohol
⚡ Moderate Interactions
- Carbamazepine
- Phenytoin
- Rifampicin
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine. Chronic alcohol consumption can induce liver enzymes, leading to increased production of a toxic metabolite of Paracetamol and a higher risk of severe liver damage. Even moderate alcohol intake may increase this risk.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Paracetamol or any component of the formulation","Severe liver disease or active liver failure","Severe kidney impairment (unless dose adjusted)","Malnutrition or chronic alcohol abuse (relative contraindication)"]
⚠️ Warnings & Precautions
["Do not exceed the maximum daily dose of Paracetamol.","Avoid concomitant use of other Paracetamol-containing products.","Use with caution in patients with liver or kidney disease.","Avoid alcohol during treatment.","Consult a doctor if symptoms persist or worsen.","Not for self-administration; must be given by a healthcare professional."]
🤱 Lactation Safety
Paracetamol is excreted in breast milk in small amounts. It is considered safe for use during breastfeeding when taken at recommended doses. Consult your doctor before use.
💊 Overdose Management
Overdose of Paracetamol can cause severe liver damage, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and loss of appetite. If overdose is suspected, seek immediate medical attention. The antidote is N-acetylcysteine, which is most effective when administered within 8 to 10 hours of ingestion. Treatment may include activated charcoal, gastric lavage, and supportive care. Monitor liver function tests and coagulation parameters.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, it should be given as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to catch up.
Additional Safety Advice
This medicine must be administered only by a healthcare professional. Do not self-administer. Inform your doctor if you have a history of liver or kidney disease, alcohol abuse, or malnutrition. Avoid taking other products containing Paracetamol while receiving this medicine to prevent overdose. Do not consume alcohol during treatment as it increases the risk of liver damage. If you are pregnant or breastfeeding, consult your doctor before receiving this medicine. Report any signs of allergic reaction, such as rash, itching, or swelling, immediately. Keep all follow-up appointments and laboratory tests as advised by your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, especially liver and kidney toxicity. Dose adjustment may be necessary based on renal and hepatic function. Monitor closely for any adverse effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Paracetamol is generally considered safe during pregnancy, but it should be used only when clearly needed.
🏥 Post-Surgery Considerations
This medicine is commonly used for post-operative pain management. It is effective and well-tolerated. Inform your surgeon if you have any liver or kidney conditions.
🦷 Dental Procedures
This medicine can be used for pain relief after dental procedures. Inform your dentist if you are taking this medicine or have any allergies.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness in some patients. Avoid driving or operating heavy machinery until you know how it affects you. Light activity is generally safe, but consult your doctor before starting any exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a healthcare setting, so it may not directly impact your work life. However, if you experience dizziness or drowsiness, avoid driving or operating machinery until the effects wear off.
🛑 When to Stop This Medicine
This medicine is usually given for a short duration. Do not stop or continue use without consulting your doctor. If you experience any serious side effects, seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine at recommended doses is generally safe, but prolonged use may increase the risk of liver and kidney damage. Regular monitoring of liver and kidney function is advised for patients on long-term therapy. Consult your doctor if you need to use this medicine for more than a few days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be used when oral administration is possible.
Evidence: Well-establishedMay be used for pain and inflammation but have different side effect profiles.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. It can be used before or after vaccination if needed for pain or fever.
📦 Storage Guide
✅ DO
Store below 25°C
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store in direct sunlight
✈️ Traveling with This Medicine
This medicine is administered by healthcare professionals and is not typically self-administered during travel. If you are prescribed this medicine for travel, carry it in its original packaging with a copy of your prescription. Store it below 25°C and protect it from light. Check with airlines and customs regarding regulations for carrying injectable medications. If you need to cross time zones, consult your doctor for dosing schedule adjustments.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 5 to 10 minutes after injection.
A: It is given as a slow intravenous injection by a healthcare professional.
A: Avoid alcohol and other Paracetamol-containing products.
A: Paracetamol is generally considered safe during pregnancy when used as directed. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for crusimol injection
View AllAlternative brands with exact same active ingredient:
-
flumol 75mg injectionElder Pharmaceuticals Ltd ₹6.09 78.4% CHEAPER
-
paraband 75mg injectionBoots Lifesciences Ltd ₹6.56 76.7% CHEAPER
-
medomol injectionMedopharm ₹7.40 73.7% CHEAPER
-
febrinil 75mg injectionSvizera Healthcare Pvt Ltd ₹11.60 58.8% CHEAPER
-
biocetamol 75mg injectionBio Medica Laboratories Pvt Ltd ₹13.13 53.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Paracetamol injection is stronger than oral tablets.
Fact: The injectable form works faster but provides similar pain relief and fever reduction as oral Paracetamol when used at equivalent doses. - Myth: Paracetamol is completely safe and has no side effects.
Fact: While generally safe at recommended doses, Paracetamol can cause serious liver damage if taken in excess or with alcohol.
🔄 Alternative Options
Generic Alternatives
- Paracetamol injection 75 mg/ml
Brand Alternatives
- Crusimol injection