paraband 75mg injection - Paracetamol (75mg/ml) medicine

Biocetamol 75mg Injection: Complete Guide to Uses, Dosage, and Safety

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🏭 Boots Lifesciences Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain, especially in the upper right quadrant
  • Dark urine or pale stools
  • Signs of allergic reaction: rash, itching, swelling of face or throat, difficulty breathing
  • Unusual bleeding or bruising
  • Severe dizziness or fainting
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is paraband 75mg injection used for?

This medicine is an intravenous form of Paracetamol used for short-term relief of moderate to severe pain and fever when oral administration is not possible. It is given by a healthcare professional and works within 5 to 10 minutes.

  • Generic Name: Paracetamol (75mg/ml)
  • Manufacturer: Boots Lifesciences Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 paraband 75mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल का इंजेक्शन है, जिसका उपयोग मध्यम से गंभीर दर्द और बुखार को कम करने के लिए किया जाता है, खासकर उन मरीजों में जो मुंह से दवा नहीं ले सकते। यह अस्पताल में डॉक्टर या नर्स द्वारा नस के माध्यम से दी जाती है। यह दर्द को कम करने और शरीर के तापमान को नियंत्रित करने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन शामिल है। कुछ मरीजों को मतली, उल्टी या सिरदर्द हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यकृत की क्षति, त्वचा पर गंभीर प्रतिक्रियाएं, और एलर्जी हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा अस्पताल में ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। अपने डॉक्टर को सभी दवाओं के बारे में बताएं, खासकर खून पतला करने वाली दवाएं। इस दवा के साथ शराब का सेवन बिल्कुल न करें। यदि आपको यकृत या गुर्दे की बीमारी है, तो डॉक्टर को बताएं। किसी भी एलर्जी के लक्षण जैसे चकत्ते, खुजली, सूजन या सांस लेने में कठिनाई हो तो तुरंत मदद लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 paraband 75mg injection Uses & Benefits

[{"condition":"Moderate to severe pain","description":"Used for short-term management of moderate to severe pain when oral administration is not possible, such as post-operative pain or pain from acute injuries.","evidence":"Well-established"},{"condition":"Fever","description":"Effective in reducing elevated body temperature in patients who cannot take oral medication.","evidence":"Well-established"},{"condition":"Post-operative analgesia","description":"Commonly used as part of multimodal analgesia after surgery to reduce opioid requirements.","evidence":"Well-established"},{"condition":"Pain in palliative care","description":"Used for pain relief in palliative settings when oral route is compromised.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Intravenous Paracetamol is sometimes used for acute migraine attacks in emergency settings, though not specifically approved for this indication.","evidence":"Limited"},{"condition":"Renal colic","description":"May be used as an adjunct for pain relief in renal colic, but evidence is limited compared to NSAIDs.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Post-operative pain, Acute injury pain, Palliative care pain

📋 Drug Information

Generic Name(s)Paracetamol (75mg/ml)
Brand Nameparaband 75mg injection
ManufacturerBoots Lifesciences Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAnalgesic & Antipyretic-PCM
Route of AdministrationParenteral (intravenous)
StorageStore below 25°C, protected from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine slowly over 15 minutes to minimize the risk of hypotension.
2
Always check the total daily dose of Paracetamol from all sources to avoid accidental overdose.
3
Monitor liver function in patients with hepatic impairment or those receiving prolonged therapy.
4
Avoid concurrent use with other Paracetamol-containing products.
5
In patients on warfarin, monitor INR closely if Paracetamol is used regularly.
6
Ensure adequate hydration before and after administration.
7
Use the lowest effective dose for the shortest duration, especially in elderly and malnourished patients.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Moderate to severe pain
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
This medicine is effective for reducing fever.
Likely Use
❌
Mild headache
Oral Paracetamol is usually preferred for mild pain.
Not Primary
❌
Inflammation
This medicine has minimal anti-inflammatory effect.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intravenous administration, Paracetamol achieves 100% bioavailability directly into the systemic circulation. There is no absorption phase as the drug bypasses the gastrointestinal tract.
DistributionParacetamol distributes rapidly into most body tissues. It crosses the placenta and is distributed into breast milk. The volume of distribution is approximately 0.8 to 1.0 L/kg in adults.
Protein BindingParacetamol is minimally bound to plasma proteins, approximately 10% to 25%.
MetabolismParacetamol is primarily metabolized in the liver via glucuronidation and sulfation to inactive metabolites. A small fraction is metabolized by cytochrome P450 2E1 to N-acetyl-p-benzoquinone imine (NAPQI), a toxic intermediate that is normally detoxified by glutathione. In overdose, glutathione stores are depleted, leading to accumulation of NAPQI and subsequent hepatotoxicity.
Half-LifeThe elimination half-life of Paracetamol is approximately 2 to 3 hours in adults with normal liver function. It may be prolonged in patients with hepatic impairment or after overdose.
ExcretionParacetamol and its metabolites are excreted primarily in the urine. Approximately 90% of the administered dose is excreted as glucuronide and sulfate conjugates, with less than 5% excreted unchanged.
Bioavailability100% for intravenous administration.
Onset of ActionPain relief begins within 5 to 10 minutes after intravenous administration. Antipyretic effect starts within 30 minutes.
Peak Plasma TimePeak plasma concentration is achieved immediately at the end of intravenous infusion.
Duration of ActionThe analgesic and antipyretic effects last approximately 4 to 6 hours.

How It Works

Paracetamol acts primarily in the central nervous system. It inhibits prostaglandin synthesis in the brain by reducing the activity of cyclooxygenase enzymes, particularly COX-2, but its exact mechanism is not fully understood. It also modulates the endogenous cannabinoid system and descending serotonergic pathways, contributing to its analgesic effect. The antipyretic effect is mediated through action on the hypothalamic heat-regulating centre, leading to peripheral vasodilation and sweating. Unlike NSAIDs, Paracetamol has minimal anti-inflammatory activity and does not inhibit platelet function or irritate the stomach lining.

Mechanism Steps

1
Central COX inhibition: Paracetamol inhibits cyclooxygenase enzymes in the central nervous system, reducing prostaglandin synthesis.
2
Reduced pain perception: Decreased prostaglandins in the brain lead to reduced pain perception and an elevated pain threshold.
3
Hypothalamic action: The drug acts on the hypothalamic temperature-regulating centre to produce antipyresis.
4
Cannabinoid pathway modulation: Paracetamol may indirectly activate cannabinoid receptors, contributing to its analgesic effect.

💡 How to Take paraband 75mg injection

Strength: Each ml contains 75 mg of Paracetamol. Available in vials of various sizes.

1This medicine is given by a healthcare professional as an intravenous injection or infusion.
2The injection is usually administered over 15 minutes to reduce the risk of hypotension.
3The dose and frequency will be determined by your doctor based on your condition.
4Inform your doctor if you have liver or kidney problems, or if you are taking other medications.
5Report any discomfort or unusual symptoms during or after the injection.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 1 gram (1000 mg) administered intravenously every 4 to 6 hours as needed, not exceeding 4 grams in 24 hours. For patients with hepatic impairment, renal impairment, or those at risk of glutathione depletion, a reduced dose or extended dosing interval may be required. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal and hepatic function. Start with the lowest effective dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance <30 mL/min), the dosing interval should be extended to every 6 to 8 hours. Dose must be individualized by a qualified clinician based on renal function.
Hepatic ImpairmentIn patients with hepatic impairment, the maximum daily dose should be reduced, and the dosing interval extended. For severe hepatic impairment, this medicine is contraindicated. Dose must be individualized by a qualified clinician based on hepatic function.
Maximum Daily DoseThe maximum recommended daily dose is 4 grams (4000 mg) for adults with normal liver function. In patients with risk factors for hepatotoxicity, the maximum daily dose should not exceed 3 grams (3000 mg).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Not applicable
This medicine is given intravenously, so food does not affect its absorption.
Alcohol
Avoid
Alcohol increases the risk of liver toxicity.

⏰ What to Do If You Miss a Dose

📌 You are in the hospital and miss a scheduled dose
→ Inform your nurse or doctor immediately.
💡 They will adjust the schedule and administer the next dose as appropriate.
📌 You are at home and miss a dose of oral Paracetamol (if prescribed)
→ Take the missed dose as soon as you remember if less than half the dosing interval has passed.
💡 If more than half the interval has passed, skip the missed dose and continue with the regular schedule. Do not double dose.

⚠️ Side Effects of paraband 75mg injection

✅ Common Side Effects

Injection site pain (Common (1-10%))
Usually resolves spontaneously. Report to nurse or doctor if severe.
Nausea (Common (1-10%))
Inform your doctor if it persists. Usually transient.
Vomiting (Uncommon (0.1-1%))
Report to healthcare provider if it continues.
Headache (Uncommon (0.1-1%))
Usually resolves on its own. Consult doctor if persistent.

🚨 Serious Side Effects

Hepatotoxicity (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) (Very rare (<0.01%))
Stop the medicine and seek emergency care if you develop rash, blisters, or peeling skin.
Anaphylaxis (Very rare (<0.01%))
Seek emergency help immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Thrombocytopenia (Very rare (<0.01%))
Report unusual bleeding or bruising to your doctor immediately.

⚠️ Rare Side Effects

Neutropenia
Seek medical advice if you develop frequent infections or fever.
Hypotension
Inform your doctor if you feel dizzy or faint after injection.
Tachycardia
Report palpitations or rapid heartbeat to your healthcare provider.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Isoniazid Moderate
Other Paracetamol products Major
Alcohol Major
Metoclopramide Minor
Cholestyramine Minor
Probenecid Moderate

🚨 Major Interactions

  • Warfarin
  • Other Paracetamol-containing products

⚡ Moderate Interactions

  • Carbamazepine, phenytoin, rifampicin
  • Isoniazid

🍷 Alcohol Interaction

Alcohol should be strictly avoided while receiving this medicine. Concurrent use of alcohol and Paracetamol can increase the risk of hepatotoxicity, even at therapeutic doses. Patients with a history of chronic alcohol use may be at higher risk and should inform their doctor before receiving this injection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Paracetamol or any component of the formulation","Severe hepatic impairment or active liver disease","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["This medicine must be administered only by a qualified healthcare professional.","Do not exceed the maximum recommended daily dose from all sources of Paracetamol.","Use with caution in patients with hepatic or renal impairment.","Avoid alcohol during treatment.","Inform your doctor if you are taking warfarin or other blood thinners.","Monitor for signs of allergic reactions during administration.","Use with caution in patients with glutathione depletion (e.g., malnutrition, chronic alcohol use).","Not recommended for routine use when oral Paracetamol is feasible."]

🤱 Lactation Safety

Paracetamol is excreted in breast milk in small amounts. It is considered safe for use during breastfeeding. Intravenous use should be discussed with a healthcare provider to ensure the benefits outweigh any potential risks to the infant.

💊 Overdose Management

Overdose of Paracetamol can cause severe liver damage, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and confusion. If overdose is suspected, seek emergency medical attention immediately. The antidote N-acetylcysteine should be administered as soon as possible, ideally within 8 to 10 hours of ingestion. Management includes gastric decontamination if appropriate, monitoring of liver function, and supportive care. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

This medicine is administered by a healthcare professional in a clinical setting. If a dose is missed, inform your nurse or doctor immediately. Do not attempt to self-administer a missed dose. The dosing schedule will be adjusted by your healthcare provider.

Additional Safety Advice

General Safety

This medicine must only be administered by a healthcare professional in a clinical setting. Do not attempt to self-administer this injection. Inform your doctor about all medications you are taking, especially blood thinners like warfarin, as Paracetamol can increase the risk of bleeding. Avoid alcohol completely while receiving this medicine, as it increases the risk of liver damage. Tell your doctor if you have a history of liver or kidney disease, or if you are malnourished or dehydrated. Do not receive this medicine if you have taken other Paracetamol-containing products in the last 4 to 6 hours. The total daily dose from all sources must not exceed the maximum recommended limit. If you experience signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing, seek emergency medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to the effects of this medicine, especially hypotension and hepatotoxicity. Dose adjustment may be needed based on renal and hepatic function. Monitor closely during administration.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Paracetamol is generally considered safe, but intravenous use should be limited to situations where oral administration is not possible.

🏥 Post-Surgery Considerations

This medicine is commonly used after surgery for pain relief. It is often part of multimodal analgesia to reduce opioid requirements. Inform your surgeon and anesthesiologist about all medications you are taking.

🦷 Dental Procedures

This medicine may be used for pain relief after dental procedures if oral administration is not possible. Inform your dentist if you are taking this medicine or have any allergies.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to support kidney function.
🥗
Avoid alcohol completely while receiving this medicine.
😴
Maintain a healthy diet rich in fruits and vegetables.
💧
Get adequate rest to aid recovery.
🧘
Follow your doctor's advice for managing the underlying condition.
🌞
Do not self-medicate with other Paracetamol products.

🏋️ Exercise Considerations

This medicine may cause dizziness or lightheadedness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. If you feel dizzy, lie down and inform your nurse or doctor.

🥗 Diet Recommendations

Avoid alcohol.
Stay well hydrated.
Eat a balanced diet to support liver health.
Avoid high-fat and processed foods if you have liver disease.

💼 Impact on Daily Work & Life

This medicine is given in a hospital or clinic setting. It may cause dizziness or drowsiness in some patients. Avoid driving or operating heavy machinery until you feel fully alert. Inform your employer if you need time off for treatment.

🛑 When to Stop This Medicine

This medicine is usually given for a short duration. Your doctor will determine when to stop based on your condition. Do not stop or change the dose without consulting your doctor. If you experience any serious side effects, inform your doctor immediately.

📅 Long-Term Use Effects

Long-term use of Paracetamol at therapeutic doses is generally safe, but prolonged high-dose use may increase the risk of liver and kidney damage. Regular monitoring of liver and kidney function is recommended for patients on long-term therapy. It is important not to exceed the maximum daily dose and to avoid alcohol. If you require pain relief for more than 10 days, consult your doctor to evaluate the underlying cause.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral Paracetamol

Preferred when the patient can swallow and absorb oral medications.

Evidence: Well-established
NSAIDs

May be used for pain and fever, but have different side effect profiles.

Evidence: Well-established
Opioid analgesics

May be used for severe pain, often in combination with Paracetamol.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you have a fever, vaccination may be postponed until you recover. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store below 25°C

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in direct sunlight

✅ DO

Keep out of reach of children

❌ DON'T

Do not use if solution is discolored or contains particles

✈️ Traveling with This Medicine

This medicine is administered in a clinical setting and is not for self-administration during travel. If you are prescribed this medicine, it will be given by a healthcare professional. If you need to carry it for emergency use, keep it in its original packaging with the prescription. Store below 25°C and protect from light. Do not freeze. Carry a copy of your prescription for customs. Inform your doctor if you are traveling across time zones, as dosing schedules may need adjustment.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man underwent knee replacement surgery and was unable to take oral medications due to nausea.
He was prescribed this medicine intravenously every 6 hours. He reported significant pain relief within 10 minutes of each dose and was able to participate in physiotherapy. His liver function tests remained normal throughout the hospital stay.
💡 Lesson: Intravenous Paracetamol provides rapid and effective pain relief when oral route is not feasible, and it is well-tolerated with proper monitoring.
👤 A 35-year-old woman with a high fever and severe throat pain was admitted to the hospital and could not swallow tablets.
She received this medicine intravenously. Her fever subsided within 30 minutes, and her pain was well controlled. She was later switched to oral Paracetamol once she could swallow.
💡 Lesson: This medicine is a valuable option for managing fever and pain in patients who cannot take oral medication, and it can be transitioned to oral therapy when appropriate.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts relieving pain within 5 to 10 minutes after intravenous administration. The effect lasts for about 4 to 6 hours.

Q: Can I take this medicine at home?

A: No, this medicine must only be administered by a qualified healthcare professional in a clinical setting.

Q: What is the maximum daily dose?

A: The maximum daily dose is 4 grams for adults with normal liver function. In patients with risk factors, it should not exceed 3 grams.

Q: Is it safe during pregnancy?

A: Paracetamol is generally considered safe during pregnancy when used at the lowest effective dose for the shortest duration. Consult your doctor before use.

Q: Can I take it with other pain medicines?

A: You should inform your doctor about all medicines you are taking. Combining with other Paracetamol-containing products can lead to overdose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • How often can I receive this injection?

🔄 Substitutes for paraband 75mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Paracetamol injection is stronger than oral Paracetamol.
    Fact: The injection is not stronger; it simply delivers the same medicine directly into the bloodstream when oral route is not possible.
  • Myth: Paracetamol injection can be self-administered at home.
    Fact: This injection must only be given by a qualified healthcare professional in a clinical setting.
  • Myth: Paracetamol injection is safe for everyone.
    Fact: It is contraindicated in severe liver disease and must be used with caution in kidney disease and other conditions.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol injection 75mg/ml

Brand Alternatives

  • Biocetamol 75mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Paracetamol injection","class":"Analgesic/Antipyretic","route":"Intravenous","onset":"5-10 minutes","duration":"4-6 hours"},{"medicine":"Paracetamol oral","class":"Analgesic/Antipyretic","route":"Oral","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Ibuprofen injection","class":"NSAID","route":"Intravenous","onset":"5-10 minutes","duration":"4-6 hours"}]

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