Anaflam TH 4 Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
- Severe skin rash or blisters
If experiencing severe symptoms, call emergency services immediately.
What is critace tp 4mg/100mg/325mg tablet used for?
This medicine is a prescription combination of Thiocolchicoside 4 mg and Aceclofenac 100 mg used for short-term relief of musculoskeletal pain and muscle spasm. It works by reducing inflammation and relaxing muscles. Take it with food, avoid alcohol, and do not exceed the prescribed dose.
- Generic Name: Thiocolchicoside + Aceclofenac
- Manufacturer: Stellar Bio-Labs
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 critace tp 4mg/100mg/325mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा थायोकोल्चिकोसाइड 4 मिलीग्राम और एसिटोक्लोफेनाक 100 मिलीग्राम का संयोजन है। इसका उपयोग मांसपेशियों में दर्द, अकड़न और सूजन के इलाज के लिए किया जाता है। यह अक्सर कमर दर्द, गर्दन दर्द, जोड़ों के दर्द और चोट लगने पर होने वाली सूजन में राहत देने के लिए दी जाती है। यह दवा मांसपेशियों को आराम देती है और दर्द व सूजन को कम करती है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए। इसे खाने के साथ लें ताकि पेट में जलन न हो। शराब का सेवन बिल्कुल न करें। गर्भवती और स्तनपान कराने वाली महिलाओं को इसका सेवन डॉक्टर की सलाह के बिना नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सीने में जलन, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। कुछ लोगों को त्वचा पर चकत्ते या खुजली भी हो सकती है। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, जिसमें काला मल या खून की उल्टी हो सकती है, शामिल है। अगर आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने दिखें तो तुरंत डॉक्टर से मिलें। लंबे समय तक इस दवा के सेवन से किडनी और लिवर की समस्या हो सकती है।
सुरक्षा सलाह: इस दवा को हमेशा खाने के साथ या दूध के साथ लें ताकि पेट में जलन न हो। शराब का सेवन बिल्कुल न करें क्योंकि इससे पेट में रक्तस्राव और लिवर की समस्या हो सकती है। डॉक्टर की सलाह के बिना कोई अन्य दर्द निवारक दवा न लें। अगर आपको पेट की बीमारी, किडनी, लिवर या दिल की समस्या है, तो डॉक्टर को पहले बताएं। इस दवा को कम से कम समय के लिए, कम से कम प्रभावी खुराक में लें। अगर आपको चक्कर आते हैं या नींद आती है तो वाहन न चलाएं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
💊 critace tp 4mg/100mg/325mg tablet Uses & Benefits
[{"condition":"Acute low back pain with muscle spasm","description":"This medicine helps relieve pain and reduces muscle spasm in the lower back, improving mobility and comfort.","evidence":"Well-established"},{"condition":"Neck pain and cervical spondylosis with spasm","description":"It reduces inflammation and relaxes neck muscles, easing pain and stiffness.","evidence":"Moderate"},{"condition":"Osteoarthritis of knee, hip, or hand","description":"Provides symptomatic relief from pain and improves joint function when muscle spasm is present.","evidence":"Well-established for Aceclofenac component; combination evidence is moderate."},{"condition":"Soft tissue injuries such as sprains and strains","description":"Helps reduce swelling, pain, and muscle spasm after minor injuries.","evidence":"Moderate"},{"condition":"Post-operative pain and spasm","description":"Sometimes used after surgery to manage pain and muscle spasm, but only under strict medical supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Tension-type headache with muscle spasm","description":"Occasionally prescribed off-label when headache is associated with neck muscle spasm.","evidence":"Limited"},{"condition":"Fibromyalgia pain flare","description":"Not a standard treatment, but sometimes used short-term for muscle spasm component.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain with muscle spasm
Also treats: Osteoarthritis, Low back pain, Neck pain, Soft tissue injuries, Post-operative pain
📋 Drug Information
| Generic Name(s) | Thiocolchicoside + Aceclofenac |
| Brand Name | Anaflam TH 4 Tablet |
| Manufacturer | Stellar Bio-Labs |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Muscle Relaxant + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the production of prostaglandins that cause pain, inflammation, and fever. Thiocolchicoside is a centrally acting muscle relaxant that binds to GABA-A receptors and strychnine-sensitive glycine receptors in the spinal cord and brainstem, reducing excessive muscle tone and spasm. Together, they address both the inflammatory pain and the muscle spasm that often accompany musculoskeletal conditions.
Mechanism Steps
💡 How to Take critace tp 4mg/100mg/325mg tablet
Strength: Each tablet contains Thiocolchicoside 4 mg and Aceclofenac 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally twice daily, preferably with meals. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not self-adjust the dose. The maximum recommended duration for continuous use without medical review is typically 7 to 14 days. Prolonged use should be avoided unless specifically advised by your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest possible duration. Close monitoring of kidney and liver function is advised. Consult a doctor for individualized dosing. |
| Renal Impairment | In patients with mild to moderate renal impairment, use with caution and consider dose reduction. In severe renal impairment (creatinine clearance <30 mL/min), this medicine is contraindicated. Consult a nephrologist or your doctor for appropriate dose adjustment. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, use with caution and consider dose reduction. In severe hepatic impairment, this medicine is contraindicated. Regular monitoring of liver function is advised. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily (i.e., Aceclofenac 200 mg and Thiocolchicoside 8 mg per day). Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of critace tp 4mg/100mg/325mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Aspirin | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| SSRIs | Moderate | |
| Corticosteroids | Moderate | |
| Cyclosporine | Moderate | |
| Digoxin | Moderate |
🚨 Major Interactions
- Warfarin and other anticoagulants
- Other NSAIDs (e.g., ibuprofen, naproxen, aspirin)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- SSRIs
- Cyclosporine
- Digoxin
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Combining alcohol with Aceclofenac increases the risk of stomach bleeding, ulcers, and liver damage. Alcohol may also enhance the drowsiness and dizziness caused by Thiocolchicoside, increasing the risk of falls and accidents.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to Aceclofenac, Thiocolchicoside, or any component of the formulation","Active or history of recurrent peptic ulcer, gastrointestinal bleeding, or perforation","Severe heart failure, ischemic heart disease, peripheral arterial disease, or cerebrovascular disease","Severe liver impairment or active liver disease","Severe kidney impairment (creatinine clearance
⚠️ Warnings & Precautions
["Take with food or milk to minimize gastrointestinal irritation.","Avoid alcohol and other NSAIDs during treatment.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of gastrointestinal bleeding, especially with long-term use.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not exceed the recommended dose or duration without medical advice.","Inform your doctor if you have a history of kidney, liver, or heart disease.","Stop the medicine and seek medical help if you experience allergic reactions or severe skin rash."]
🤱 Lactation Safety
It is not known whether Aceclofenac and Thiocolchicoside are excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, this medicine should be used with caution in breastfeeding women. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, dizziness, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be considered if the patient presents early. Monitor vital signs, kidney and liver function, and manage complications accordingly.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine with food or milk to reduce the chance of stomach upset. Do not crush, chew, or break the tablet unless your doctor advises otherwise. Avoid alcohol completely while taking this medicine because it can increase the risk of stomach bleeding and liver problems. Do not take other pain relievers, especially other NSAIDs like ibuprofen, naproxen, or aspirin, without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or asthma, tell your doctor before starting this medicine. Use the lowest effective dose for the shortest possible duration. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Keep all follow-up appointments and report any unusual bleeding, bruising, or swelling immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events with NSAIDs. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Avoid concomitant use of other NSAIDs or anticoagulants. Consult a doctor for individualized dosing and monitoring.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like Aceclofenac may affect ovulation and are not recommended during pregnancy, especially in the third trimester. Discuss alternative treatment options with your doctor.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to manage pain and muscle spasm, but only under strict medical supervision. It may increase the risk of bleeding, so inform your surgeon if you are taking it before any surgical procedure. Your doctor will decide the appropriate dose and duration based on your condition.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may increase the risk of bleeding during dental work. Your dentist may advise you to stop the medicine temporarily or take precautions. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercises or activities that may exacerbate pain or cause injury. Gentle stretching and low-impact exercises are generally safe, but consult your doctor or physiotherapist before starting any new exercise regimen. If you experience dizziness or drowsiness, avoid exercises that require balance or coordination.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate heavy machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. Inform your employer if your work involves operating machinery or driving. Generally, you can continue your daily activities with caution.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any serious side effects such as black stools, vomiting blood, severe abdominal pain, allergic reactions, or signs of liver or kidney problems. Do not stop the medicine abruptly without consulting your doctor, especially if you have been taking it for a prolonged period. Your doctor will advise you on the appropriate duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to increased risks of gastrointestinal bleeding, kidney impairment, liver injury, and cardiovascular events. If long-term use is necessary, regular monitoring of kidney and liver function, blood counts, and cardiovascular health is advised. The lowest effective dose should be used for the shortest duration. Consult your doctor regularly to reassess the need for continued treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and muscle spasm.
Evidence: Well-establishedMay help relieve muscle spasm and pain.
Evidence: ModerateSome evidence for chronic pain relief.
Evidence: LimitedMay provide localized pain relief with fewer systemic side effects.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider about all medicines you are taking. Live vaccines should be avoided if you are on immunosuppressive therapy, but this medicine is not immunosuppressive.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking the medicine at the same intervals as prescribed; consult your doctor for specific advice. Keep it in your carry-on luggage to avoid loss. Check local customs regulations regarding prescription medicines before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet, but the full effect may take a few hours. Muscle relaxant effects may take longer.
A: No, it is best taken with food or milk to reduce the risk of stomach upset and ulcers.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol should be completely avoided while taking this medicine as it increases the risk of stomach bleeding and liver problems.
A: This medicine is not recommended during pregnancy, especially in the third trimester. Consult your doctor for alternative options.
🤔 Common Patient Concerns
🔄 Substitutes for critace tp 4mg/100mg/325mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia aceclofenac+thiocolchicoside 100mg/4mg tabletDavaindia Generic Pharmacy ₹60.00 72.6% CHEAPER
-
xynac th 100mg/4mg tabletArlak Biotech Pvt Ltd ₹60.94 72.2% CHEAPER
-
dinal-mx tabletSapco Laboratories Pvt Ltd ₹61.88 71.7% CHEAPER
-
inflamex tabletExcella Life Sciences Pvt Ltd ₹72.19 67% CHEAPER
-
Thicop AP 4mg/100mg/325mg TabletPasco Pharmaceuticals ₹73.13 66.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects and should be avoided unless specifically advised by a doctor. - Myth: It is safe to take this medicine on an empty stomach.
Fact: Taking this medicine on an empty stomach increases the risk of stomach upset and ulcers. Always take it with food or milk. - Myth: This medicine is a steroid.
Fact: This medicine is not a steroid. It contains an NSAID and a muscle relaxant. - Myth: You can stop this medicine abruptly without consulting a doctor.
Fact: Always consult your doctor before stopping this medicine, especially if you have been taking it for more than a few days.
🔄 Alternative Options
Generic Alternatives
- Thiocolchicoside + Aceclofenac generic
Brand Alternatives
- Anaflam TH 4 Tablet