dinal-mx tablet - Thiocolchicoside (4mg) + Aceclofenac (100mg) medicine

dinal-mx tablet

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🏭 Sapco Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is dinal-mx tablet used for?

This medicine contains Thiocolchicoside (4mg) + Aceclofenac (100mg) and is used to treat PAIN ANALGESICS. Thiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxation; Aceclofenac: In. Always consult your doctor before use.

  • Generic Name: Thiocolchicoside + Aceclofenac
  • Manufacturer: Sapco Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 dinal-mx tablet Uses & Benefits

Acute musculoskeletal pain, muscle spasms, inflammatory conditions

Off-label uses: Not well established

📋 Drug Information

Generic Name(s)Thiocolchicoside + Aceclofenac
Brand NameAnaflam TH 4 Tablet
ManufacturerSapco Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassMuscle Relaxant + NSAID
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration
DistributionWidely distributed in body tissues
Protein BindingThiocolchicoside: ~13%; Aceclofenac: >99%
MetabolismThiocolchicoside: Hepatic; Aceclofenac: Hepatic via CYP2C9
Half-LifeThiocolchicoside: ~7 hours; Aceclofenac: ~4 hours
ExcretionThiocolchicoside: Renal (70-80%); Aceclofenac: Renal (70-80%)
BioavailabilityThiocolchicoside: ~25%; Aceclofenac: ~100%
Onset of ActionThiocolchicoside: 30-60 min; Aceclofenac: 30 min
Peak Plasma TimeThiocolchicoside: 1-2 hours; Aceclofenac: 1-3 hours
Duration of ActionThiocolchicoside: 4-6 hours; Aceclofenac: 12-24 hours

How It Works

Thiocolchicoside: Acts on GABA-A and glycine receptors to produce muscle relaxation; Aceclofenac: Inhibits COX-1 and COX-2, reducing prostaglandin synthesis

Mechanism Steps

1Thiocolchicoside binds to GABA-A receptors, enhancing inhibitory neurotransmission
2Thiocolchicoside also acts on glycine receptors, promoting spinal inhibition
3Aceclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes
4Inhibition of COX reduces conversion of arachidonic acid to prostaglandins
5Decreased prostaglandins lead to reduced pain and inflammation

💡 How to Take dinal-mx tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of dinal-mx tablet

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Dizziness
Somnolence

🚨 Serious Side Effects

GI bleeding
Peptic ulcer
Renal failure
Hepatotoxicity
Anaphylaxis

⚠️ Rare Side Effects

Blood dyscrasias
Stevens-Johnson syndrome
Seizures

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Aspirin Major Increased GI ulceration risk
Other NSAIDs Major Additive GI and renal toxicity
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect, increased nephrotoxicity
Anticoagulants Moderate Increased bleeding risk
Corticosteroids Moderate Increased GI ulceration risk
Antacids Minor Reduced absorption of aceclofenac
Digoxin Minor Possible increased digoxin levels
Phenytoin Minor Possible increased phenytoin levels

🚨 Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Aspirin
  • Other NSAIDs

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

🍷 Alcohol Interaction

Increased risk of GI bleeding and hepatotoxicity

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, pregnancy (third trimester), lactation, children

🤱 Lactation Safety

Not recommended; excreted in breast milk

💊 Overdose Management

Symptomatic and supportive; gastric lavage, activated charcoal

⏰ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

🔄 Substitutes for dinal-mx tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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