Alcoxia-MR Tablet: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe allergic reaction (rash, itching, swelling)
- Persistent nausea or vomiting
If experiencing severe symptoms, call emergency services immediately.
What is z cox th 60mg/4mg tablet used for?
This medicine is a combination of Etoricoxib (60 mg) and Thiocolchicoside (4 mg) used for short-term relief of acute musculoskeletal pain and muscle spasm. It works by reducing inflammation and relaxing muscles. It is taken orally with food, usually once or twice daily, and should not be used for more than 7 days without medical advice.
- Generic Name: Etoricoxib (60mg) + Thiocolchicoside (4mg)
- Manufacturer: Arlak Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 z cox th 60mg/4mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरिकॉक्सिब 60 मिलीग्राम और थायोकोल्चिकोसाइड 4 मिलीग्राम का संयोजन है। इसका उपयोग तीव्र मस्कुलोस्केलेटल दर्द और मांसपेशियों की ऐंठन के अल्पकालिक उपचार के लिए किया जाता है, जैसे कि कमर दर्द, गर्दन दर्द, मोच और खिंचाव। यह दर्द और सूजन को कम करने के साथ-साथ मांसपेशियों को आराम देने में मदद करता है। इसे डॉक्टर के निर्देशानुसार ही लें और 7 दिनों से अधिक न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट दर्द, जी मिचलाना, अपच, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट या आंतों में रक्तस्राव, एलर्जी प्रतिक्रिया, गुर्दे की समस्या, यकृत की सूजन और रक्तचाप में वृद्धि शामिल हो सकते हैं। यदि आपको काला या खूनी मल, खून की उल्टी, गंभीर पेट दर्द, सांस लेने में कठिनाई, या त्वचा या आंखों का पीलापन दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक या निर्धारित अवधि से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। गोली को पूरा निगलें, चबाएं नहीं। इस दवा के साथ शराब का सेवन न करें। यदि आपको चक्कर आते हैं या नींद आती है तो वाहन न चलाएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या गर्भधारण की योजना बना रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 z cox th 60mg/4mg tablet Uses & Benefits
[{"condition":"Acute low back pain","description":"This medicine helps relieve pain and muscle spasm associated with acute low back pain, improving mobility and reducing discomfort.","evidence":"Well-established for short-term use"},{"condition":"Neck pain (cervical spondylosis)","description":"It reduces inflammation and muscle spasm in the neck, providing symptomatic relief.","evidence":"Commonly used, evidence supports short-term benefit"},{"condition":"Musculoskeletal sprains and strains","description":"Used to alleviate pain and spasm following soft tissue injuries.","evidence":"Well-established for acute injuries"},{"condition":"Post-operative pain and spasm","description":"May be prescribed short-term after surgery to manage pain and muscle spasm.","evidence":"Limited to short-term use under medical supervision"}]
Off-label uses: [{"condition":"Tension-type headache with muscle spasm","description":"Sometimes prescribed off-label when muscle tension contributes to headache.","evidence":"Limited"},{"condition":"Fibromyalgia flare-ups","description":"May be used off-label for short-term relief of muscle pain and spasm in fibromyalgia.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Sprains and strains, Post-operative pain
📋 Drug Information
| Generic Name(s) | Etoricoxib (60mg) + Thiocolchicoside (4mg) |
| Brand Name | z cox th 60mg/4mg tablet |
| Manufacturer | Arlak Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Etoricoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, reducing the production of prostaglandins that mediate pain, inflammation, and fever. Thiocolchicoside acts as a centrally acting muscle relaxant by binding to GABA-A and strychnine-sensitive glycine receptors in the spinal cord and brainstem, thereby reducing muscle spasms. Together, they provide relief from both inflammation and muscle spasm.
Mechanism Steps
💡 How to Take z cox th 60mg/4mg tablet
Strength: Tablet containing Etoricoxib 60 mg and Thiocolchicoside 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once or twice daily, as prescribed by your doctor. The exact dose and duration depend on the condition being treated, its severity, and your response to therapy. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with mild to moderate renal impairment. Not recommended in severe renal impairment (creatinine clearance <30 mL/min). Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. Not recommended in severe hepatic impairment (Child-Pugh C). Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | The maximum recommended daily dose of Etoricoxib is 90 mg. For this combination, the maximum daily dose is typically one tablet twice daily, but must not exceed the prescribed dose. Do not exceed the dose recommended by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of z cox th 60mg/4mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Ketoconazole | Moderate | |
| Rifampicin | Moderate | |
| Aspirin | Minor |
🚨 Major Interactions
- Warfarin
- ACE inhibitors / ARBs
- Diuretics
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP3A4 inducers (e.g., rifampicin)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding, ulcers, and liver damage. It may also worsen drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to Etoricoxib, Thiocolchicoside, or any component of the formulation","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe heart failure (NYHA class II-IV)","Uncontrolled hypertension","Severe liver disease (Child-Pugh C)","Severe kidney disease (creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with dehydration or volume depletion.","Monitor blood pressure regularly.","Use with caution in patients with a history of gastrointestinal ulcers or bleeding.","May impair ability to drive or operate machinery; avoid until you know how it affects you.","Do not use for longer than the recommended duration without medical advice.","Inform your doctor if you have heart disease, kidney disease, liver disease, or asthma.","Avoid concomitant use with other NSAIDs.","Alcohol should be avoided.","Not recommended for children under 16 years."]
🤱 Lactation Safety
Not established from the available information. It is not known whether Etoricoxib or Thiocolchicoside passes into breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for guidance.
💊 Overdose Management
Overdose of this medicine may cause severe gastrointestinal, kidney, liver, and cardiovascular effects. If you suspect an overdose, seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs and organ function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take the tablet with food or milk to reduce stomach upset. Swallow it whole with a glass of water; do not crush or chew. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver problems. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of heart disease, high blood pressure, kidney or liver problems, asthma, or stomach ulcers. Do not take other NSAIDs or pain relievers without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor blood pressure, kidney and liver function regularly. Avoid if possible in frail elderly patients.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are trying to conceive, consult your doctor for safer alternatives for pain management. Etoricoxib may affect ovulation and is not recommended in the third trimester due to risk of premature closure of the ductus arteriosus.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery for short-term pain and muscle spasm management. However, it should be used with caution due to increased risk of bleeding and kidney problems. Follow your surgeon's instructions carefully and do not exceed the prescribed dose or duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop the medicine temporarily before surgery. Do not stop without consulting your prescribing doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may worsen your condition while taking this medicine. Gentle stretching and low-impact exercises may be beneficial, but consult your doctor or physiotherapist before starting any exercise program. Stop immediately if you experience increased pain, dizziness, or shortness of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. If your work involves physical labor, take precautions to avoid injury. Consult your doctor if you have concerns about your work.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience any serious side effects such as severe abdominal pain, black stools, allergic reactions, or signs of liver or kidney problems. Do not stop abruptly without consulting your doctor if you have been taking it for more than a few days. Your doctor will advise you on the appropriate duration and tapering if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of Etoricoxib can increase the risk of cardiovascular events, gastrointestinal bleeding, kidney impairment, and liver damage. Thiocolchicoside may cause liver enzyme elevations. Regular monitoring of blood pressure, kidney and liver function is advised if used for extended periods. Consult your doctor for alternative treatments if long-term pain management is needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedHelps relax muscles and reduce pain.
Evidence: Commonly usedMay help with pain relief.
Evidence: LimitedImproves flexibility and reduces muscle tension.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture and heat. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines. Do not leave it in a hot car or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Etoricoxib begins to provide pain relief within 1 hour of oral administration. The muscle relaxant effect may take a few hours to become noticeable.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not take other NSAIDs or pain relievers without consulting your doctor, as it may increase the risk of side effects.
A: Do not stop taking this medicine abruptly without consulting your doctor. Your doctor will advise you on the appropriate duration of treatment.
🤔 Common Patient Concerns
🔄 Substitutes for z cox th 60mg/4mg tablet
View AllAlternative brands with exact same active ingredient:
-
etovero t 60mg/4mg tabletBiorika Healthcare ₹70.31 66.7% COSTLIER
-
davaindia etoricoxib+thiocolchicoside 60mg/4mg tabletDavaindia Generic Pharmacy ₹75.00 77.8% COSTLIER
-
etodose th 60mg/4mg tabletBioshine Healthcare Pvt Ltd ₹84.38 100% COSTLIER
-
yaxoflex 60mg/4mg tabletYaxon BioCare Pvt Ltd ₹89.06 111.1% COSTLIER
-
etorbee-ch 60mg/4mg tabletBonsai Pharma ₹93.75 122.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects. - Myth: It is safe to take this medicine without a prescription.
Fact: This is a prescription medicine. It should only be taken under medical supervision. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol should be avoided as it increases the risk of stomach bleeding and liver problems.
🔄 Alternative Options
Generic Alternatives
- Etoricoxib + Thiocolchicoside
Brand Alternatives
- Alcoxia-MR Tablet