craft-o 1gm/20mg syrup - Sucralfate (1gm) + Oxetacaine (20mg) medicine

craft-o 1gm/20mg syrup

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🏭 Quest Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

What is craft-o 1gm/20mg syrup used for?

This medicine contains Sucralfate (1gm) + Oxetacaine (20mg) and is used to treat GASTRO INTESTINAL. Sucralfate forms a protective barrier over ulcer sites; oxetacaine provides local anesthetic effect. Always consult your doctor before use.

  • Generic Name: Sucralfate + Oxetacaine
  • Manufacturer: Quest Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Category B
  • Prescription Required: Yes
💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 craft-o 1gm/20mg syrup Uses & Benefits

Gastric ulcer, duodenal ulcer, gastroesophageal reflux disease (GERD), esophagitis

Off-label uses: Stress ulcer prophylaxis, Mucositis

📋 Drug Information

Generic Name(s)Sucralfate + Oxetacaine
Brand NameAxid O Suspension
ManufacturerQuest Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassGastrointestinal protective agent
Route of AdministrationOral suspension
StorageStore at room temperature (20-25°C); protect from freezing
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMinimal systemic absorption; acts locally in GI tract
DistributionNot significantly distributed due to minimal absorption
Protein BindingNegligible
MetabolismNot metabolized; acts locally
Half-LifeNot applicable (local action)
ExcretionPrimarily fecal as unabsorbed drug
BioavailabilityNegligible systemic bioavailability
Onset of ActionRapid (minutes) for local effect
Peak Plasma TimeNot applicable
Duration of ActionUp to 6 hours after dose

How It Works

Sucralfate forms a protective barrier over ulcer sites; oxetacaine provides local anesthetic effect

Mechanism Steps

1Sucralfate polymerizes in acidic environment to form a viscous paste
2Paste adheres to ulcer site, forming a protective barrier
3Barrier prevents further acid and pepsin damage
4Oxetacaine provides local anesthetic effect on gastric mucosa
5Pain relief occurs due to anesthetic action

💡 How to Take craft-o 1gm/20mg syrup

Follow your doctor's prescription exactly.

⚠️ Side Effects of craft-o 1gm/20mg syrup

✅ Common Side Effects

Constipation
Nausea
Dry mouth
Dizziness

🚨 Serious Side Effects

Hypersensitivity reactions
Bezoar formation

⚠️ Rare Side Effects

Aluminum toxicity (with renal impairment)
Hypophosphatemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids Major Reduced efficacy of sucralfate
Cimetidine Major Decreased absorption of cimetidine
Digoxin Major Decreased absorption of digoxin
Fluoroquinolones Major Decreased absorption of fluoroquinolones
Tetracyclines Major Decreased absorption of tetracyclines
Theophylline Major Decreased absorption of theophylline
Warfarin Major Decreased absorption of warfarin
Ketoconazole Moderate Decreased absorption of ketoconazole
Phenytoin Moderate Decreased absorption of phenytoin
Quinidine Moderate Decreased absorption of quinidine
Ranitidine Moderate Decreased absorption of ranitidine
Aluminum-containing antacids Minor Increased aluminum absorption

🚨 Major Interactions

  • Antacids
  • Cimetidine
  • Digoxin
  • Fluoroquinolones
  • Tetracyclines
  • Theophylline
  • Warfarin

⚡ Moderate Interactions

  • Ketoconazole
  • Phenytoin
  • Quinidine
  • Ranitidine

🍷 Alcohol Interaction

May increase gastric irritation; avoid alcohol

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to sucralfate or oxetacaine

🤱 Lactation Safety

Limited data; use with caution

💊 Overdose Management

Gastric lavage; supportive care; no specific antidote

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

🔄 Substitutes for craft-o 1gm/20mg syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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