andiflex 50mg injection - Nandrolone Decanoate (50mg/ml) medicine

Andiflex 50mg Injection: Complete Medicine Guide

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🏭 Quest Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category This medicine is contraindicated during pregnancy as it may cause harm to the fetus. Effective contraception should be used during treatment. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of the skin or eyes (jaundice)
  • Severe abdominal pain or swelling
  • Chest pain or shortness of breath
  • Sudden weakness or difficulty speaking
  • Blood in vomit or black, tarry stools
  • Decreased urine output or swelling in legs
  • Severe headache with vision changes

If experiencing severe symptoms, call emergency services immediately.

What is andiflex 50mg injection used for?

This medicine is an anabolic steroid injection containing nandrolone decanoate, used under medical supervision for conditions like anemia of chronic kidney disease and wasting syndromes. It is not for athletic performance enhancement.

  • Generic Name: Nandrolone Decanoate
  • Manufacturer: Quest Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 andiflex 50mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा नैंड्रोलोन डेकानोएट नामक एक एनाबॉलिक स्टेरॉयड है, जिसका उपयोग कुछ विशेष चिकित्सीय स्थितियों में किया जाता है। यह गुर्दे की बीमारी से जुड़े एनीमिया, वेस्टिंग सिंड्रोम और कुछ प्रकार के ऑस्टियोपोरोसिस के इलाज में मदद कर सकती है। यह दवा मांसपेशियों की वृद्धि और लाल रक्त कोशिकाओं के उत्पादन को बढ़ावा देती है। इसका उपयोग केवल डॉक्टर की देखरेख में ही किया जाना चाहिए। इसे इंजेक्शन के रूप में मांसपेशियों में दिया जाता है। गर्भवती महिलाओं, स्तनपान कराने वाली महिलाओं, प्रोस्टेट कैंसर या स्तन कैंसर वाले पुरुषों और गंभीर यकृत रोग वाले रोगियों को यह दवा नहीं दी जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन, तरल पदार्थ का जमाव, मुँहासे और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में यकृत विषाक्तता, हृदय संबंधी समस्याएं, रक्त के थक्के और हार्मोनल असंतुलन शामिल हो सकते हैं। पुरुषों में अंडकोष का सिकुड़ना और स्तन वृद्धि हो सकती है, जबकि महिलाओं में आवाज भारी होना और चेहरे पर बाल बढ़ना जैसे पुरुषीकरण के लक्षण हो सकते हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल योग्य डॉक्टर की देखरेख में ही दी जानी चाहिए। इसे स्वयं न लगाएं और न ही शरीर सौष्ठव के लिए उपयोग करें। उपचार से पहले अपने सभी चिकित्सीय इतिहास, विशेषकर हृदय, यकृत, गुर्दे और प्रोस्टेट की समस्याओं के बारे में डॉक्टर को बताएं। उपचार के दौरान नियमित रूप से यकृत और गुर्दे की कार्यप्रणाली, रक्त गणना और लिपिड प्रोफाइल की जांच कराएं। शराब का सेवन न करें क्योंकि इससे यकृत को नुकसान हो सकता है। गर्भावस्था से बचने के लिए प्रभावी गर्भनिरोधक उपाय करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 andiflex 50mg injection Uses & Benefits

[{"condition":"Anemia of chronic kidney disease","description":"This medicine can stimulate erythropoiesis and improve hemoglobin levels in some patients with anemia associated with chronic kidney disease, though it is not a first-line treatment.","evidence":"Limited"},{"condition":"Wasting syndrome associated with HIV/AIDS","description":"It may be used to promote weight gain and lean body mass in patients with HIV-related wasting, but only as part of a comprehensive treatment plan.","evidence":"Limited"},{"condition":"Osteoporosis in selected patients","description":"This medicine may be used to increase bone mineral density in certain forms of osteoporosis, such as corticosteroid-induced osteoporosis, but other agents are generally preferred.","evidence":"Limited"},{"condition":"Hereditary angioedema","description":"Nandrolone decanoate has been used off-label to prevent attacks of hereditary angioedema by increasing C1 esterase inhibitor levels, but this is not a standard approved use.","evidence":"Limited"}]

Off-label uses: [{"condition":"Male hypogonadism","description":"Sometimes used off-label for testosterone replacement, but it is not a preferred therapy due to its adverse effect profile and potential for abuse.","evidence":"Limited"},{"condition":"Athletic performance enhancement","description":"This is an illegal and unsafe off-label use. It is not recommended and can cause serious health harm.","evidence":"Not established from the available information."}]

Primary treatment for: Anemia of chronic kidney disease

Also treats: Wasting syndrome, Osteoporosis, Hereditary angioedema

📋 Drug Information

Generic Name(s)Nandrolone Decanoate
Brand NameAlkem Nandrolone 50mg Injection
ManufacturerQuest Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassAnabolic steroid
Route of AdministrationIntramuscular
StorageStore this medicine at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Do not freeze.
Shelf LifeThe shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the product label for the exact expiry date.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only under medical supervision; never self-inject.
2
Monitor liver function tests regularly due to the risk of hepatotoxicity.
3
Assess cardiovascular status before and during therapy, especially in patients with heart disease.
4
Advise patients to report any signs of virilization or fluid retention immediately.
5
Use effective contraception in women of childbearing potential during treatment.
6
Monitor prostate-specific antigen in men over 40 before and during therapy.
7
Avoid concomitant use with hepatotoxic drugs or anticoagulants.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic fatigue due to anemia
This medicine may be prescribed for anemia of chronic kidney disease.
Likely Use
✅
Muscle wasting
This medicine may be used in wasting syndromes.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is administered intramuscularly and is absorbed slowly from the injection site. The esterified form is hydrolyzed to release the active nandrolone.
DistributionNandrolone is widely distributed in the body, with high concentrations in muscle, liver, and fat tissue. It crosses the placenta and is excreted in breast milk.
Protein BindingNandrolone is approximately 80% bound to plasma proteins, primarily to sex hormone-binding globulin and albumin.
MetabolismThis medicine is metabolized in the liver by esterase enzymes that cleave the decanoate ester, releasing free nandrolone, which is further metabolized by reduction and conjugation.
Half-LifeThe elimination half-life of nandrolone decanoate is approximately 6 to 12 days after intramuscular injection.
ExcretionThis medicine is excreted primarily in the urine as conjugated metabolites, with a small amount in the feces.
BioavailabilityThe bioavailability of this medicine after intramuscular injection is high, but the exact percentage is not established from the available information.
Onset of ActionThe onset of action of this medicine is gradual, with effects typically becoming noticeable within 1 to 2 weeks after injection.
Peak Plasma TimePeak plasma concentrations of nandrolone are reached approximately 3 to 7 days after intramuscular injection.
Duration of ActionThe duration of action of this medicine is approximately 2 to 3 weeks after a single intramuscular injection.

How It Works

This medicine is a synthetic anabolic-androgenic steroid that binds to androgen receptors in target tissues, leading to increased protein synthesis, positive nitrogen balance, and enhanced erythropoietin production. It also has progestational activity and can suppress gonadotropin secretion.

Mechanism Steps

1
Binding to androgen receptor: This medicine binds to the androgen receptor in the cytoplasm of target cells, leading to receptor activation.
2
Translocation to nucleus: The activated receptor-ligand complex moves into the nucleus and binds to specific DNA sequences.
3
Gene transcription: This binding alters the transcription of specific genes, leading to increased protein synthesis and cell growth.
4
Erythropoietin stimulation: This medicine stimulates the production of erythropoietin in the kidneys, which increases red blood cell production.
5
Suppression of gonadotropins: It suppresses the release of luteinizing hormone and follicle-stimulating hormone from the pituitary, reducing natural testosterone production.

💡 How to Take andiflex 50mg injection

Strength: This medicine is available as a 50 mg/ml intramuscular injection.

1This medicine must be administered by a qualified healthcare professional.
2The injection is given into a large muscle, usually the gluteus maximus.
3The injection site should be rotated to prevent irritation.
4Do not self-administer this medicine.
5Follow your doctor's instructions regarding the frequency of injections.

Dosage Information

Adult DosageThe dosage of this medicine must be individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and clinical response. Typical adult doses range from 25 mg to 100 mg intramuscularly every 2 to 4 weeks, but this is for educational reference only. Do not self-administer.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the cardiovascular and hepatic side effects of this medicine. Dose adjustments should be made cautiously by a clinician.
Renal ImpairmentThis medicine should be used with caution in patients with renal impairment. Dose adjustment may be necessary based on renal function.
Hepatic ImpairmentThis medicine is contraindicated in severe liver disease. In mild to moderate hepatic impairment, dose reduction and close monitoring are advised.
Maximum Daily DoseThe maximum daily dose is not established from the available information. Dosing is typically intermittent (every 2-4 weeks) rather than daily.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing required
This medicine is injectable and not affected by food.
Grapefruit
No known interaction
This medicine is injectable and not affected by grapefruit.

⏰ What to Do If You Miss a Dose

📌 If you miss a scheduled injection
→ Contact your healthcare provider to reschedule as soon as possible.
💡 Do not attempt to double the dose.
📌 If you miss a dose and it is almost time for the next one
→ Skip the missed dose and continue with your regular schedule.
💡 Never take two doses at the same time.

⚠️ Side Effects of andiflex 50mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold pack to the injection site and avoid rubbing. Consult a doctor if pain persists.
Fluid retention (Common (5-10%))
Reduce salt intake and inform your doctor if swelling worsens.
Acne (Common (5-10%))
Keep skin clean and consult a dermatologist if severe.
Headache (Common (5-10%))
Rest and stay hydrated. Consult a doctor if headaches are persistent.

🚨 Serious Side Effects

Liver toxicity (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Cardiovascular events (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, or sudden weakness.
Pulmonary embolism (Rare (<0.1%))
Seek emergency care if you have sudden difficulty breathing, chest pain, or coughing up blood.
Testicular atrophy (Uncommon (1-5%))
Consult your doctor if you notice testicular shrinkage or reduced libido.

⚠️ Rare Side Effects

Hepatic peliosis
Seek immediate medical attention if you experience severe abdominal pain or signs of internal bleeding.
Liver tumors
Report any abdominal swelling or pain to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Insulin Major
Corticosteroids Moderate
Cyclosporine Moderate

🚨 Major Interactions

  • Warfarin
  • Insulin
  • Hepatotoxic drugs

⚡ Moderate Interactions

  • Corticosteroids
  • Cyclosporine

🍷 Alcohol Interaction

Alcohol should be avoided while using this medicine because it can increase the risk of liver toxicity and may worsen fluid retention.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Breastfeeding","Prostate cancer in men","Breast cancer in men","Hypercalcemia","Severe liver disease","Known hypersensitivity to nandrolone decanoate"]

⚠️ Warnings & Precautions

["This medicine should be used with caution in patients with cardiovascular disease, as it can cause fluid retention and hypertension.","Hepatic function should be monitored regularly due to the risk of liver toxicity.","Men should be monitored for prostate changes and advised to report urinary symptoms.","Women may experience virilization effects such as deepening of voice and increased facial hair; these may be irreversible.","This medicine can suppress natural testosterone production and cause testicular atrophy.","Use with caution in patients with diabetes, as it may affect blood glucose control.","This medicine may increase the risk of bleeding when used with anticoagulants."]

🤱 Lactation Safety

This medicine is excreted in breast milk and may cause serious adverse effects in a nursing infant. Breastfeeding is not recommended during treatment.

💊 Overdose Management

Overdose with this medicine is unlikely due to its intramuscular route and medical supervision. In case of accidental overdose, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a scheduled dose of this medicine, contact your healthcare provider to reschedule. Do not attempt to double the dose to catch up.

Additional Safety Advice

General Safety

This medicine must only be used under the supervision of a qualified healthcare professional. Do not self-administer or use it for bodybuilding or athletic performance. Before starting treatment, inform your doctor about all your medical conditions, especially heart disease, liver disease, kidney disease, prostate problems, or bleeding disorders. Regular monitoring of liver function, kidney function, blood counts, and lipid profile is essential during therapy. Avoid alcohol consumption as it can increase the risk of liver damage. Use effective contraception during treatment and for at least 6 months after stopping if you are of childbearing potential. Do not share this medicine with others. Keep all follow-up appointments and report any side effects promptly. Store this medicine as directed and never use it after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of cardiovascular and hepatic side effects. Close monitoring and dose adjustments are recommended.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy and should be avoided if you are planning to become pregnant. Use effective contraception during treatment and for at least 6 months after stopping.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine, as it may affect healing and increase the risk of complications. It may need to be stopped before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may affect bleeding and healing. Your dentist may recommend postponing elective dental work.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart and joints.
🥗
Engage in regular low-impact exercise as advised by your doctor.
😴
Avoid alcohol to protect your liver.
💧
Eat a balanced diet rich in fruits, vegetables, and lean proteins.
🧘
Get adequate sleep to support overall health.
🌞
Stay hydrated but monitor fluid intake if you have heart or kidney issues.

🏋️ Exercise Considerations

Consult your doctor before starting any exercise program. Avoid strenuous activities if you have heart or kidney problems. Low-impact exercises like walking or swimming are generally safer.

🥗 Diet Recommendations

Limit sodium intake to manage fluid retention.
Include potassium-rich foods if your doctor approves.
Avoid high-fat and processed foods to protect your liver.
Stay hydrated but follow fluid restrictions if advised.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some patients. Avoid driving or operating heavy machinery until you know how it affects you. Inform your employer if your job involves such activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your doctor will determine when to stop based on your response and any side effects. If you experience serious side effects, seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to liver toxicity, cardiovascular complications, hormonal imbalances, and suppression of natural testosterone production. Regular monitoring of liver function, renal function, lipid profile, and blood counts is essential. The risk of adverse effects increases with prolonged use, so the lowest effective dose should be used for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Erythropoiesis-stimulating agents

These are often used for anemia of chronic kidney disease and may be safer alternatives.

Evidence: Well-established
Nutritional support

For wasting syndromes, nutritional support and appetite stimulants may be used.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions known with this medicine. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Check the customs regulations of your destination country regarding anabolic steroids, as they may be controlled substances. Store it at room temperature and avoid direct sunlight. If you need to adjust the timing of your dose due to time zone changes, consult your doctor for guidance.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with chronic kidney disease and anemia
He was prescribed this medicine by his nephrologist to help with his anemia. After a few weeks, his hemoglobin levels improved, and he felt less fatigued. He experienced mild fluid retention, which was managed by reducing salt intake. He emphasized the importance of regular blood tests and never missing follow-up appointments.
💡 Lesson: Regular monitoring and adherence to the prescribed schedule are crucial for safe and effective treatment.
👤 A 40-year-old woman with hereditary angioedema
She received this medicine off-label to prevent angioedema attacks. While it reduced the frequency of attacks, she developed acne and mild voice deepening. Her doctor adjusted the dose and monitored her closely. She learned that any unusual symptoms should be reported promptly.
💡 Lesson: Off-label use requires careful monitoring and open communication with the healthcare provider.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Effects of this medicine may begin within 1 to 2 weeks, but full benefits may take several weeks to months.

Q: What should I do if I experience side effects?

A: Report any side effects to your doctor immediately. Do not stop the medicine without consulting your doctor.

Q: Can I take this medicine if I am pregnant?

A: No, this medicine is contraindicated during pregnancy as it may harm the fetus.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for andiflex 50mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe for bodybuilding.
    Fact: This medicine is a prescription drug with serious risks and is not approved for bodybuilding. It can cause liver damage, heart problems, and hormonal imbalances.
  • Myth: This medicine is a vitamin injection.
    Fact: This medicine is an anabolic steroid, not a vitamin. It has potent hormonal effects and must be used only under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Nandrolone decanoate

Brand Alternatives

  • Andiflex 50mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Nandrolone decanoate","class":"Anabolic steroid","route":"Intramuscular","half_life":"6-12 days"},{"medicine":"Testosterone enanthate","class":"Anabolic steroid","route":"Intramuscular","half_life":"4-5 days"}]

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