cosklot plus 250mg/250mg tablet - Uses, Price, Side Effects & Substitutes
What is cosklot plus 250mg/250mg tablet used for?
Arsyl T 250mg/250mg Tablet (Tranexamic Acid + Ethamsylate) is used to treat BLOOD RELATED. It contains Tranexamic Acid (250mg) + Ethamsylate (250mg), which Tranexamic acid: Competitively inhibits plasminogen activation, reducing fibrino. Always consult your doctor before use. Take as prescribed.
- Generic Name: Tranexamic Acid + Ethamsylate
- Manufacturer: Oaknet Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cosklot plus 250mg/250mg tablet Uses & Benefits
Menorrhagia, epistaxis, post-surgical bleeding, hematuria, dental bleeding in hemophiliacs
Off-label uses: Hereditary angioedema (tranexamic acid), prevention of bleeding in cardiac surgery
๐ Drug Information
| Generic Name(s) | Tranexamic Acid + Ethamsylate |
| Brand Name | Arsyl T 250mg/250mg Tablet |
| Manufacturer | Oaknet Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Antifibrinolytic + Hemostatic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Tranexamic acid: Competitively inhibits plasminogen activation, reducing fibrinolysis. Ethamsylate: Reduces capillary bleeding by improving platelet adhesion and decreasing capillary permeability.
Mechanism Steps
๐ก How to Take cosklot plus 250mg/250mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cosklot plus 250mg/250mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Dizziness
- Headache
๐จ Serious Side Effects
- Thromboembolism
- Seizures
- Hypotension
- Anaphylaxis
โ ๏ธ Rare Side Effects
- Visual disturbances
- Renal failure
- Rash
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Heparin | Major | Increased bleeding risk |
| Aspirin | Moderate | Increased bleeding risk |
| Clopidogrel | Moderate | Increased bleeding risk |
๐จ Major Interactions
- Warfarin
- Heparin
- Direct oral anticoagulants
- Thrombolytics
โก Moderate Interactions
- Aspirin
- NSAIDs
- Clopidogrel
- Antiplatelet agents
โน๏ธ Minor Interactions
- Oral contraceptives
- Hormone replacement therapy
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
No known interaction
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active thromboembolic disease, severe renal impairment, history of seizures (tranexamic acid)
๐ Monitoring Parameters
Bleeding time, clotting time, renal function, signs of thrombosis
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Symptomatic and supportive treatment; no specific antidote
โฐ Missed Dose
Take as soon as remembered; skip if almost time for next dose; do not double dose