coriphen suspension
What is coriphen suspension used for?
Alex P Syrup (Chlorpheniramine Maleate + Paracetamol) is used to treat RESPIRATORY. It contains Chlorpheniramine Maleate (1mg/5ml) + Paracetamol (125mg/5ml), which Chlorpheniramine: H1-receptor antagonist; Paracetamol: COX inhibition in CNS. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlorpheniramine Maleate + Paracetamol
- Manufacturer: McW Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ coriphen suspension Uses & Benefits
๐ Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Paracetamol |
| Brand Name | Alex P Syrup |
| Manufacturer | McW Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Chlorpheniramine: H1-receptor antagonist; Paracetamol: COX inhibition in CNS
Mechanism Steps
๐ก How to Take coriphen suspension
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of coriphen suspension
โ Common Side Effects
- Drowsiness
- Dry mouth
- Nausea
- Dizziness
๐จ Serious Side Effects
- Hepatotoxicity
- Severe allergic reaction
- Blood dyscrasias
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Agranulocytosis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Increased anticholinergic and CNS effects |
| Alcohol | Major | Increased CNS depression and hepatotoxicity |
| CNS depressants | Major | Additive sedation |
| Warfarin | Moderate | Increased INR with high doses of paracetamol |
| Isoniazid | Moderate | Increased hepatotoxicity risk |
| Rifampin | Moderate | Reduced paracetamol efficacy |
| Anticholinergics | Minor | Additive anticholinergic effects |
| Corticosteroids | Minor | Increased intraocular pressure risk |
๐จ Major Interactions
- MAOIs
- Alcohol
- CNS depressants
โก Moderate Interactions
- Warfarin
- Isoniazid
- Rifampin
โน๏ธ Minor Interactions
- Anticholinergics
- Corticosteroids
๐ฝ๏ธ Food Interactions
Avoid alcohol, No significant food interactions
๐ท Alcohol Interaction
Increased CNS depression and hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, MAOI use
๐ Monitoring Parameters
Liver function tests, renal function, CBC
๐คฑ Lactation Safety
Use with caution; small amounts excreted in breast milk
๐ Overdose Management
Activated charcoal, N-acetylcysteine for paracetamol overdose; supportive care
โฐ Missed Dose
Take as soon as remembered; skip if near next dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.