cool zone-spas tablet - Uses, Price, Side Effects & Substitutes
What is cool zone-spas tablet used for?
Cool Zone-Spas Tablet (Omeprazole + Dicyclomine) is used to treat GASTRO INTESTINAL. It contains Omeprazole (10mg) + Dicyclomine (10mg), which Omeprazole irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Omeprazole + Dicyclomine
- Manufacturer: Minova Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cool zone-spas tablet Uses & Benefits
Gastroesophageal reflux disease, Peptic ulcer disease, Irritable bowel syndrome with spasm, Functional dyspepsia
Off-label uses: Zollinger-Ellison syndrome, Gastroparesis, Cyclic vomiting syndrome
๐ Drug Information
| Generic Name(s) | Omeprazole + Dicyclomine |
| Brand Name | Cool Zone-Spas Tablet |
| Manufacturer | Minova Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Proton Pump Inhibitor + Anticholinergic |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Omeprazole irreversibly inhibits H+/K+ ATPase in gastric parietal cells, reducing acid secretion. Dicyclomine blocks muscarinic receptors, reducing smooth muscle spasms.
Mechanism Steps
๐ก How to Take cool zone-spas tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cool zone-spas tablet
โ Common Side Effects
- Headache
- Nausea
- Diarrhea
- Constipation
- Dry mouth
- Dizziness
๐จ Serious Side Effects
- Severe allergic reactions
- Acute interstitial nephritis
- Clostridium difficile diarrhea
- Bone fracture
- Hypomagnesemia
โ ๏ธ Rare Side Effects
- Pancreatitis
- Hepatotoxicity
- Agranulocytosis
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased INR and bleeding risk |
| Clopidogrel | Major | Reduced clopidogrel efficacy |
| Methotrexate | Major | Increased methotrexate toxicity |
| Ketoconazole | Moderate | Reduced ketoconazole absorption |
๐จ Major Interactions
- Cilostazol
- Clopidogrel
- Methotrexate
- Rilpivirine
- St. John's Wort
โก Moderate Interactions
- Diazepam
- Phenytoin
- Warfarin
- Ketoconazole
- Iron salts
โน๏ธ Minor Interactions
- Caffeine
- Theophylline
- Digoxin
๐ฝ๏ธ Food Interactions
Food delays absorption of omeprazole; dicyclomine may be taken with food to reduce GI upset.
๐ท Alcohol Interaction
Alcohol may increase risk of GI irritation and worsen side effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to components, Glaucoma, Obstructive uropathy, Myasthenia gravis, Severe hepatic impairment
๐ Monitoring Parameters
Liver function tests, Renal function, Magnesium levels (long-term), Bone density (long-term)
๐คฑ Lactation Safety
Omeprazole is excreted in breast milk; dicyclomine may suppress lactation. Use with caution.
๐ Overdose Management
Symptomatic and supportive treatment; gastric lavage if recent ingestion.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next.