Consticalo 2 Tablet (Prucalopride 2mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or persistent diarrhoea leading to dehydration
- Fast, irregular, or pounding heartbeat
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe abdominal pain or cramping
- Blood in stool or vomit
- Signs of dehydration such as dry mouth, reduced urine output, or dizziness
If experiencing severe symptoms, call emergency services immediately.
What is convio 2mg tablet used for?
This medicine is a prescription medicine used to treat chronic constipation in adults when other treatments have not worked. It works by stimulating specific receptors in the gut to improve bowel movements. The usual dose is 2 mg once daily.
- Generic Name: Prucalopride
- Manufacturer: Wellvio Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 convio 2mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा प्रुकैलोप्राइड 2 मिलीग्राम युक्त एक प्रिस्क्रिप्शन टैबलेट है, जिसका उपयोग वयस्कों में पुरानी कब्ज (क्रोनिक इडियोपैथिक कब्ज) के इलाज के लिए किया जाता है, जब अन्य दवाओं से लाभ नहीं होता। यह आंतों में विशिष्ट रिसेप्टर्स को उत्तेजित करके आंतों की गति को बढ़ाती है, जिससे मल त्याग में सुधार होता है। यह दवा दस्त या मल को नरम करने वाली साधारण दवा नहीं है। इसका सेवन डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, जी मिचलाना, दस्त, पेट दर्द और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन गंभीर दस्त, धड़कन तेज होना, या एलर्जी प्रतिक्रिया हो सकती है। यदि आपको कोई गंभीर या लगातार लक्षण महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को स्वयं कम या ज्यादा न करें। टैबलेट को पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ या बिना भी लिया जा सकता है, लेकिन भोजन के साथ लेने से जी मिचलाना कम हो सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे या हृदय की समस्या है, तो डॉक्टर को बताएं। शराब से बचें क्योंकि इससे चक्कर आ सकते हैं। बच्चों की पहुंच से दूर रखें।
💊 convio 2mg tablet Uses & Benefits
- [{"condition":"Chronic idiopathic constipation","description":"This medicine is used to treat chronic constipation in adults when other laxatives have not provided adequate relief.
- It helps increase the frequency and improve the consistency of bowel movements.","evidence":"Well-established"},{"condition":"Constipation-predominant irritable bowel syndrome (IBS-C)","description":"Sometimes prescribed to help relieve constipation and abdominal discomfort in people with IBS-C, though this is not its primary approved use.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"May be used off-label to improve gastric emptying in people with delayed stomach emptying, but evidence is limited.","evidence":"Limited"}]
Off-label uses: [{"condition":"Opioid-induced constipation","description":"May be used to treat constipation caused by opioid pain medicines, but it is not specifically approved for this purpose.","evidence":"Limited"},{"condition":"Post-operative ileus","description":"Occasionally used to help restore bowel function after surgery, but this is not a standard approved indication.","evidence":"Limited"}]
Primary treatment for: Chronic idiopathic constipation
Also treats: Irritable bowel syndrome with constipation, Gastroparesis, Opioid-induced constipation
📋 Drug Information
| Generic Name(s) | Prucalopride |
| Brand Name | Consticalo 2 Tablet |
| Manufacturer | Wellvio Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin (5-HT4) receptor agonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, away from moisture and direct sunlight. Do not refrigerate unless specified by the manufacturer. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture. Check the expiry date on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. The World Health Organization has not issued specific guidelines for the use of prucalopride in chronic constipation. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has not published specific guidelines for prucalopride. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively stimulating the serotonin 5-HT4 receptors located in the gastrointestinal tract. When these receptors are activated, they trigger the release of acetylcholine and other neurotransmitters that enhance the peristaltic reflex. This reflex is responsible for the coordinated wave-like contractions that move contents through the intestines. By enhancing this reflex, the medicine increases the frequency and strength of bowel movements, leading to improved stool passage. Unlike some older medicines in this class, it has a much higher selectivity for the 5-HT4 receptor, which reduces the risk of side effects related to other serotonin receptors.
Mechanism Steps
💡 How to Take convio 2mg tablet
Strength: This medicine is available as an immediate-release tablet containing 2 mg of Prucalopride.
Dosage Information
| Adult Dosage | The usual recommended dose for adults is 2 mg once daily, taken orally with or without food. For patients with severe renal impairment (creatinine clearance less than 30 mL/min), the recommended dose is 1 mg once daily. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients based on age alone. However, because elderly patients may have reduced renal function, dose adjustment may be necessary if kidney impairment is present. The dose must be individualized by a qualified clinician. |
| Renal Impairment | For patients with severe renal impairment (creatinine clearance less than 30 mL/min), the recommended dose is 1 mg once daily. In patients with end-stage renal disease requiring dialysis, use is not recommended. For mild to moderate renal impairment, no dose adjustment is needed. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No dose adjustment is required for patients with mild to moderate hepatic impairment. In patients with severe hepatic impairment, caution is advised as there is limited data. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 mg for adults with normal renal function. For patients with severe renal impairment, the maximum daily dose is 1 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of convio 2mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cisapride | Major | |
| Amiodarone | Major | |
| Ketoconazole | Moderate | |
| Rifampicin | Moderate | |
| Hyoscine | Minor |
🚨 Major Interactions
- Other 5-HT4 agonists (e.g., cisapride, tegaserod)
- Drugs that prolong QT interval (e.g., amiodarone, sotalol, haloperidol)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness and fatigue associated with this medicine. It is advisable to avoid or limit alcohol consumption while taking this medicine, especially when starting treatment or adjusting the dose.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to prucalopride or any component of the tablet","Intestinal obstruction or blockage","Perforation of the stomach or intestinal wall","Severe inflammatory bowel conditions such as Crohn's disease or ulcerative colitis with toxic megacolon","Severe renal impairment requiring dialysis","Children under 18 years of age (safety and efficacy not established)"]
⚠️ Warnings & Precautions
["This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with a history of cardiac arrhythmias or QT prolongation.","Patients with severe kidney disease may need a lower dose; consult your doctor.","Do not use this medicine for constipation that is not chronic or that has not been evaluated by a doctor.","If you experience severe diarrhoea, stop the medicine and seek medical advice to prevent dehydration.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Because many medicines are excreted in breast milk, caution should be exercised when this medicine is administered to a breastfeeding woman. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
There is limited information on overdose with this medicine. In case of suspected overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor for signs of excessive gastrointestinal motility such as severe diarrhoea, abdominal cramps, and dehydration. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Swallow the tablet whole with a glass of water; do not crush or chew it. This medicine can be taken with or without food, but taking it with food may help reduce nausea. Inform your doctor if you have kidney or liver problems, heart rhythm disorders, or if you are pregnant or breastfeeding. Avoid alcohol while taking this medicine as it may worsen dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep this medicine out of reach of children. Store it at room temperature away from moisture and direct sunlight. Do not use it after the expiry date. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Never double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and diarrhoea. Renal function should be assessed before starting treatment, as dose adjustment may be needed if kidney function is reduced. Start with the lowest effective dose and monitor closely for side effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting or continuing this medicine. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks and may recommend alternative treatments.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to help restore bowel function, but this is not a standard approved indication. If you are scheduled for surgery, inform your surgeon and anesthesiologist about this medicine. It may need to be stopped before certain surgeries, especially those involving the gastrointestinal tract.
🦷 Dental Procedures
There are no specific precautions for dental procedures while taking this medicine. However, inform your dentist about all medicines you are taking. If you experience dizziness, avoid driving to and from dental appointments.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged as it can help improve bowel motility. However, if you experience dizziness or fatigue after taking this medicine, avoid strenuous activities until you know how it affects you. Stay hydrated during exercise, especially if you have diarrhoea.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities, but if you experience persistent side effects, consult your doctor. It is advisable to take the medicine at a time that allows you to manage any initial side effects, such as taking it in the evening if nausea is a problem.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects such as severe diarrhoea, palpitations, or allergic reactions, stop the medicine and seek immediate medical attention. Your doctor may decide to discontinue treatment if your constipation improves or if you experience intolerable side effects. Always follow your doctor's guidance.
📅 Long-Term Use Effects
Long-term use of this medicine has been studied for up to 12 months and is generally well tolerated. It does not appear to cause dependence or tolerance. However, regular follow-up with your doctor is recommended to assess ongoing need and monitor for any rare side effects. If you stop taking it, constipation may return, so discuss a plan with your doctor before discontinuing.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing fiber intake can help soften stool and promote regularity.
Evidence: Well-establishedThese draw water into the bowel to soften stool and are often first-line for chronic constipation.
Evidence: Well-establishedHelps retrain pelvic floor muscles for people with dyssynergic defecation.
Evidence: ModerateCertain strains may improve stool frequency and consistency, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations while taking this medicine. However, always inform your healthcare provider about all medicines you are taking before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in your carry-on luggage to avoid extreme temperatures in checked baggage. Keep it away from direct sunlight and moisture. If crossing time zones, continue taking your dose at the same time each day according to your home schedule, or consult your doctor for adjustments. Check local customs regulations regarding prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some people notice improvement within 24 hours, but it may take up to a week for the full effect. Continue taking it as prescribed.
A: Yes, it is usually taken once daily. Your doctor will determine how long you should take it based on your condition.
A: Common side effects include headache, nausea, diarrhoea, and abdominal pain. These are usually mild and temporary.
A: It has been studied for up to 12 months of use. Your doctor will periodically assess whether continued treatment is necessary.
A: It is best to avoid or limit alcohol as it may increase dizziness and fatigue.
A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip it and take your next dose at the regular time. Do not double dose.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor if you are pregnant or planning to become pregnant.
A: It has few interactions, but it may interact with certain heart medicines and drugs that affect liver enzymes. Always inform your doctor about all medicines you take.
🤔 Common Patient Concerns
🔄 Substitutes for convio 2mg tablet
View AllAlternative brands with exact same active ingredient:
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fitgut 2mg tabletHetero Drugs Ltd ₹191.68 29.5% CHEAPER
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prucapride 2 tabletCare Formulation Labs Pvt Ltd ₹206.25 24.1% CHEAPER
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calopride 2mg tabletCorona Remedies Pvt Ltd ₹214.69 21% CHEAPER
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muvpru 2mg tabletEmcure Pharmaceuticals Ltd ₹214.69 21% CHEAPER
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prugonist 2 tabletMylan Pharmaceuticals Pvt Ltd ₹215.50 20.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a laxative and can be used for occasional constipation.
Fact: This medicine is not a laxative. It is a prescription medicine for chronic constipation and should only be used under medical supervision. - Myth: This medicine works immediately after the first dose.
Fact: It may take a few days to notice the full effect. Some people experience improvement within 24 hours, but it can take up to a week. - Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription-only medicine. It should only be taken if prescribed by a qualified doctor.
🔄 Alternative Options
Generic Alternatives
- Prucalopride 2 mg tablet
Brand Alternatives
- Consticalo 2 tablet