convio 1mg tablet - Prucalopride (1mg) medicine

convio 1mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Wellvio Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 4, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 04, 2026

What is convio 1mg tablet used for?

Consticalo 2 Tablet (Prucalopride) is used to treat GASTRO INTESTINAL. It contains Prucalopride (1mg), which Selective serotonin 5-HT4 receptor agonist; enhances gastrointestinal motility b. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Prucalopride
  • Manufacturer: Wellvio Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š convio 1mg tablet Uses & Benefits

Chronic idiopathic constipation; constipation-predominant irritable bowel syndrome (IBS-C).

Off-label uses: Gastroparesis; chronic intestinal pseudo-obstruction.

๐Ÿ“‹ Drug Information

Generic Name(s)Prucalopride
Brand NameConsticalo 2 Tablet
ManufacturerWellvio Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin (5-HT4) receptor agonist-Prokinetic agent
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached within 2-3 hours.
DistributionWidely distributed; volume of distribution approximately 567 L.
Protein BindingApproximately 30% bound to plasma proteins.
MetabolismMetabolized primarily via CYP3A4; minor metabolism via CYP2D6 and CYP2C9.
Half-LifeApproximately 24-30 hours.
ExcretionPrimarily excreted in urine (60-65% as unchanged drug and metabolites) and feces (20-25%).
BioavailabilityApproximately 90%.
Onset of ActionWithin 1-2 hours.
Peak Plasma Time2-3 hours.
Duration of ActionUp to 24 hours.

How It Works

Selective serotonin 5-HT4 receptor agonist; enhances gastrointestinal motility by increasing acetylcholine release from enteric neurons.

Mechanism Steps

1Prucalopride binds to 5-HT4 receptors on enteric neurons.
2Activation of 5-HT4 receptors stimulates adenylate cyclase.
3Increased cAMP levels lead to enhanced acetylcholine release.

๐Ÿ’ก How to Take convio 1mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of convio 1mg tablet

โœ… Common Side Effects

  • Headache
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Flatulence

๐Ÿšจ Serious Side Effects

  • Severe diarrhea leading to electrolyte imbalance
  • Hypersensitivity reactions
  • Cardiac arrhythmias (rare)

โš ๏ธ Rare Side Effects

  • QT prolongation
  • Seizures
  • Hepatotoxicity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased prucalopride exposure due to CYP3A4 inhibition
Rifampin Major Decreased prucalopride exposure due to CYP3A4 induction
Atropine Moderate Reduced prokinetic effect due to anticholinergic action
Morphine Moderate Opposing effects on gastrointestinal motility

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole)
  • CYP3A4 inducers (e.g., rifampin)

โšก Moderate Interactions

  • Anticholinergic drugs
  • Opioid analgesics

โ„น๏ธ Minor Interactions

  • Metoclopramide
  • Domperidone

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

No specific interaction; alcohol may worsen gastrointestinal symptoms.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to prucalopride; intestinal obstruction; severe inflammatory bowel disease; renal impairment (CrCl <30 mL/min).

๐Ÿ“Š Monitoring Parameters

Bowel movement frequency; renal function; signs of hypersensitivity.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk in animal studies.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; monitor for arrhythmias.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 04, 2026

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๐Ÿ”„ Substitutes for convio 1mg tablet

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Alternative brands with exact same active ingredient (Prucalopride (1mg)):

Medical Note: Always consult your doctor before switching medications.

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