Consticalo 1 Tablet (Prucalopride 1 mg): Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or persistent diarrhoea with signs of dehydration such as dry mouth, dizziness, or reduced urine output.
- Blood in stool or vomit.
- Severe abdominal pain or cramping.
- Signs of an allergic reaction: rash, itching, swelling of the face, lips, or throat, difficulty breathing.
- Irregular heartbeat or palpitations.
- Yellowing of the skin or eyes (jaundice).
- Severe headache that does not go away.
If experiencing severe symptoms, call emergency services immediately.
What is convio 1mg tablet used for?
This medicine contains Prucalopride 1 mg, a selective serotonin 5-HT4 receptor agonist used to treat chronic idiopathic constipation in adults. It works by stimulating gut motility, helping to increase bowel movement frequency and improve stool consistency. It is taken orally once daily, with or without food. Common side effects include headache, nausea, and diarrhoea. It is available only by prescription.
- Generic Name: Prucalopride
- Manufacturer: Wellvio Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 convio 1mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा प्रुकैलोप्राइड 1 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग वयस्कों में दीर्घकालिक इडियोपैथिक कब्ज के इलाज के लिए किया जाता है। यह आंतों की गति को बढ़ाकर मल त्याग की आवृत्ति को बढ़ाती है और मल की स्थिरता में सुधार करती है। यह दवा उन रोगियों के लिए है जिन्हें अन्य उपचारों से लाभ नहीं हुआ है। यह केवल डॉक्टर के पर्चे पर ही मिलती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, दस्त और पेट दर्द शामिल हैं। ये आमतौर पर हल्के होते हैं और उपचार शुरू करने पर कुछ समय बाद कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन गंभीर दस्त, निर्जलीकरण, या एलर्जी प्रतिक्रिया हो सकती है। यदि आपको कोई गंभीर लक्षण महसूस हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या गुर्दे या यकृत की समस्या है, तो डॉक्टर को सूचित करें। इस दवा को लेते समय शराब का सेवन न करें। ड्राइविंग या मशीनरी चलाने से बचें जब तक कि आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है। दवा को बच्चों की पहुंच से दूर रखें और निर्देशानुसार ही लें।
💊 convio 1mg tablet Uses & Benefits
- [{"condition":"Chronic idiopathic constipation","description":"This medicine is used to treat chronic idiopathic constipation in adults when other treatments have not provided adequate relief.
- It helps to increase the frequency of bowel movements and improve stool consistency.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gastroparesis","description":"Sometimes prescribed off-label to improve gastric emptying in people with gastroparesis, but evidence is limited.","evidence":"Limited"},{"condition":"Constipation-predominant irritable bowel syndrome","description":"May be used off-label for constipation-predominant irritable bowel syndrome, but it is not approved for this indication.","evidence":"Limited"}]
Primary treatment for: Chronic idiopathic constipation
Also treats: Gastroparesis (off-label), Constipation-predominant irritable bowel syndrome (off-label)
📋 Drug Information
| Generic Name(s) | Prucalopride |
| Brand Name | Consticalo 2 Tablet |
| Manufacturer | Wellvio Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin (5-HT4) receptor agonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively stimulating the serotonin 5-HT4 receptors located in the gastrointestinal tract. When these receptors are activated, they trigger a series of events that enhance the release of acetylcholine, a neurotransmitter that promotes smooth muscle contraction and peristalsis. This leads to faster transit of stool through the colon and improved bowel movement frequency. Unlike some other prokinetic agents, this medicine does not significantly affect other serotonin receptor subtypes, which reduces the risk of certain side effects.
Mechanism Steps
💡 How to Take convio 1mg tablet
Strength: Prucalopride 1 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual recommended dose of this medicine for adults is 1 mg taken orally once daily. The dose may be adjusted by your doctor based on your response and tolerability. For patients with severe renal impairment (creatinine clearance less than 30 mL/min), the recommended dose is 0.5 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients based on age alone. However, because elderly patients may have reduced renal function, dose should be selected with caution and renal function should be monitored. |
| Renal Impairment | For patients with severe renal impairment (creatinine clearance less than 30 mL/min), the recommended dose is 0.5 mg once daily. This medicine is not recommended for patients with end-stage renal disease requiring dialysis. |
| Hepatic Impairment | No dose adjustment is required for patients with mild to moderate hepatic impairment. In patients with severe hepatic impairment, this medicine should be used with caution and dose adjustment may be necessary. |
| Maximum Daily Dose | The maximum recommended daily dose is 1 mg for adults with normal renal function. For patients with severe renal impairment, the maximum daily dose is 0.5 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of convio 1mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Erythromycin | Moderate | |
| Verapamil | Moderate | |
| Grapefruit juice | Moderate |
🚨 Major Interactions
- Ketoconazole
- Clarithromycin
⚡ Moderate Interactions
- Erythromycin
- Verapamil
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness and drowsiness associated with this medicine. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Prucalopride or any component of the formulation","Intestinal obstruction or perforation","Severe inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis)","Toxic megacolon","Severe renal impairment requiring dialysis","Children and adolescents under 18 years of age"]
⚠️ Warnings & Precautions
["This medicine may cause dizziness or fatigue; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with a history of cardiac arrhythmias or QT prolongation.","Dose adjustment is required in patients with severe renal impairment.","Use with caution in patients with severe hepatic impairment.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not exceed the recommended dose.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. Because many medicines are excreted in breast milk, caution should be exercised when this medicine is administered to a breastfeeding woman. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
There is limited information on overdose with this medicine. In case of overdose, seek immediate medical attention. Treatment should be symptomatic and supportive. Monitor vital signs and observe for signs of increased side effects such as severe diarrhoea, headache, or nausea. There is no specific antidote.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before starting this medicine, tell your doctor if you have any kidney or liver problems, or if you have a history of heart rhythm disturbances. This medicine may cause dizziness or fatigue in some people; avoid driving or operating heavy machinery until you know how it affects you. Do not take this medicine if you are allergic to Prucalopride or any of the other ingredients. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine is not recommended for children and adolescents under 18 years of age. Do not exceed the prescribed dose. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use this medicine after the expiry date printed on the pack. Always follow your doctor's instructions and read the patient information leaflet provided with the medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on renal function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not fully established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may need to be temporarily stopped before surgery, especially if bowel rest is required. Follow your doctor's instructions.
🦷 Dental Procedures
This medicine does not typically interfere with dental procedures. However, inform your dentist about all medicines you are taking. If you need to fast for a procedure, adjust your dose timing as advised by your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe while taking this medicine. However, if you experience dizziness or fatigue, avoid strenuous activities until you know how the medicine affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Otherwise, it should not significantly impact your daily work or activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or if your doctor decides to discontinue it, they will provide instructions on how to stop safely. Abruptly stopping may cause constipation to return.
📅 Long-Term Use Effects
Long-term use of this medicine has been studied in clinical trials for up to 24 months and has been generally well-tolerated. However, regular monitoring of kidney and liver function may be advised, especially in patients with underlying conditions. Some patients may develop tolerance, and the dose may need adjustment. If you experience any new or worsening symptoms, consult your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Increasing dietary fibre can help relieve constipation in some people.
Evidence: Well-establishedMedicines like polyethylene glycol can help soften stool and promote bowel movements.
Evidence: Well-establishedFor patients with pelvic floor dysfunction, biofeedback can be helpful.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as recommended by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. Store at room temperature and protect from moisture. If crossing time zones, continue taking your dose at the same time each day as closely as possible. Check local customs regulations regarding prescription medicines before travelling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to work within a few days, but it may take up to a week to see the full benefit. If you do not notice improvement after a week, consult your doctor.
A: Yes, this medicine can be taken with or without food. Taking it with food may help reduce nausea.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: This medicine has been studied for long-term use in chronic constipation. Your doctor will monitor you regularly to ensure it remains safe and effective for you.
A: It is advisable to avoid or limit alcohol while taking this medicine, as it may increase dizziness and drowsiness.
🤔 Common Patient Concerns
🔄 Substitutes for convio 1mg tablet
View AllAlternative brands with exact same active ingredient:
-
fitgut 1mg tabletHetero Drugs Ltd ₹124.72 25.3% CHEAPER
-
calopride 1mg tabletCorona Remedies Pvt Ltd ₹139.69 16.3% CHEAPER
-
prumotion 1mg tabletKoye Pharmaceuticals Pvt ltd ₹139.69 16.3% CHEAPER
-
prugonist 1mg tabletMylan Pharmaceuticals Pvt Ltd ₹140.50 15.8% CHEAPER
-
prucapla 1mg tabletCipla Ltd ₹144.38 13.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a laxative.
Fact: This medicine is not a laxative; it is a prokinetic agent that stimulates gut motility. - Myth: This medicine can be taken for occasional constipation.
Fact: This medicine is approved for chronic idiopathic constipation and should only be used under medical supervision. - Myth: This medicine works immediately.
Fact: This medicine may take a few days to show its full effect. - Myth: This medicine is safe for everyone.
Fact: This medicine is not suitable for people with certain bowel conditions, severe kidney disease, or children under 18.
🔄 Alternative Options
Generic Alternatives
- Prucalopride 1 mg tablet
Brand Alternatives
- Consticalo 1 tablet