Comcet A 2.5mg/60mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe allergic reaction with rash and itching
- Irregular heartbeat or palpitations
- Yellowing of skin or eyes
- Severe abdominal pain
- Unusual bleeding or bruising
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is comcet a 2.5mg/60mg tablet used for?
This medicine is a combination of levocetirizine (antihistamine) and ambroxol (mucolytic) used to treat allergic symptoms with productive cough. It relieves sneezing, runny nose, and thins mucus to ease cough.
- Generic Name: Levocetirizine + Ambroxol
- Manufacturer: Lifecom Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 comcet a 2.5mg/60mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसेटिरिज़िन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग एलर्जी के लक्षणों जैसे छींक, नाक बहना, खुजली और बलगम वाली खांसी के इलाज के लिए किया जाता है। यह एलर्जी को कम करती है और बलगम को पतला करके खांसी को आसान बनाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, सिरदर्द और हल्का पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चकत्ते, या दिल की धड़कन में अनियमितता महसूस हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अधिक मात्रा में न लें। इस दवा को लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 comcet a 2.5mg/60mg tablet Uses & Benefits
[{"condition":"Allergic rhinitis with productive cough","description":"Relieves sneezing, runny nose, itching, and watery eyes while thinning mucus to ease cough.","evidence":"Well-established"},{"condition":"Sinusitis with thick mucus","description":"Helps reduce allergic symptoms and facilitates drainage of thick sinus secretions.","evidence":"Moderate"},{"condition":"Productive cough due to respiratory allergies","description":"Levocetirizine controls allergy while ambroxol helps expel mucus.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Chronic urticaria with mucus","description":"Sometimes prescribed off-label for itching with associated mucus, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis with productive cough
Also treats: Sinusitis, Bronchitis, Chronic urticaria
📋 Drug Information
| Generic Name(s) | Levocetirizine + Ambroxol |
| Brand Name | Amicet |
| Manufacturer | Lifecom Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Mucolytic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Levocetirizine is a selective peripheral H1-receptor antagonist. It competes with histamine for binding sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract, thereby reducing allergic symptoms. Ambroxol is a mucolytic agent that increases serous bronchial secretion, reduces mucus viscosity, and promotes ciliary clearance, making cough more productive. Together, they address both allergic and mucus-related components of respiratory conditions.
Mechanism Steps
💡 How to Take comcet a 2.5mg/60mg tablet
Strength: Tablet containing Levocetirizine 2.5 mg and Ambroxol 60 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, as prescribed by your doctor. The exact dose and frequency depend on the condition being treated, your age, weight, and kidney/liver function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially drowsiness. Dose adjustment may be necessary based on renal function. Consult your doctor. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. In severe renal impairment (creatinine clearance <10 mL/min), levocetirizine is contraindicated. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution and consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily, but this must be confirmed by your doctor. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of comcet a 2.5mg/60mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| MAOIs | Major | |
| Ketoconazole | Moderate | |
| Erythromycin | Moderate | |
| Anticholinergics | Moderate |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol may increase drowsiness and dizziness caused by levocetirizine. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levocetirizine, ambroxol, or any component","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with renal or hepatic impairment.","Not recommended for children under 6 years.","Consult doctor if symptoms persist beyond 7 days.","Do not exceed the recommended dose."]
🤱 Lactation Safety
Levocetirizine and ambroxol may pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause increased drowsiness, dizziness, nausea, and tachycardia. Seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol while taking this medicine, as it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for a longer duration than prescribed without consulting your doctor. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to drowsiness and dizziness. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental issues. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel drowsy or dizzy. Light activities like walking are generally safe. Consult your doctor before starting any exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, affecting your ability to drive or operate machinery. Avoid such activities until you know how it affects you. It may also cause dry mouth, so keep water handy.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, or if you experience any serious side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of levocetirizine may lead to tolerance or rare blood disorders. Ambroxol is generally safe for short-term use. Regular monitoring of kidney and liver function may be advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve nasal congestion and allergy symptoms.
Evidence: Well-establishedHelps loosen mucus and ease breathing.
Evidence: Traditional💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor if you are due for any vaccinations while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Levocetirizine starts working within 1 hour, while ambroxol's mucolytic effect may take a few hours. You may notice relief from sneezing and runny nose quickly, but cough improvement may take a day or two.
A: Consult your doctor before combining with other cold medicines, as they may contain similar ingredients and increase the risk of side effects.
A: The safety of this combination during pregnancy is not well established. Consult your doctor before taking it.
🤔 Common Patient Concerns
🔄 Substitutes for comcet a 2.5mg/60mg tablet
View AllAlternative brands with exact same active ingredient:
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cyptic 60mg/2.5mg/500mg/5mg tabletPax Healthcare ₹32.81 64.1% COSTLIER
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elzik tabletAden Healthcare ₹32.81 64.1% COSTLIER
-
histalev a plus tabletAltruist Pharmacia Pvt Ltd ₹32.81 64.1% COSTLIER
-
kargip tabletAcinom Healthcare ₹32.81 64.1% COSTLIER
-
ambrolid cold tabletMayGriss Healthcare Pvt. Ltd ₹33.00 65% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of cough.
Fact: It is effective only for allergic cough with mucus; it does not treat dry cough or infections. - Myth: It is safe to take without a prescription.
Fact: It is a prescription medicine and should only be taken under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Levocetirizine + Ambroxol combination tablets from other manufacturers
Brand Alternatives
- Comcet A 2.5mg/60mg tablet