Brutal Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face or throat, difficulty breathing.
- Signs of liver problems: yellowing of skin or eyes, dark urine, severe abdominal pain.
- Signs of blood disorders: unusual bruising or bleeding, fever, sore throat.
- Severe skin reactions: blistering or peeling skin, mouth sores.
- Persistent vomiting or diarrhea leading to dehydration.
- Confusion, seizures, or unusual behavior.
- Decreased urine output or swelling in legs.
If experiencing severe symptoms, call emergency services immediately.
What is bemisol 400mg/150mg tablet used for?
This medicine is a combination of albendazole and levamisole used to treat intestinal worm infections. It works by paralyzing and killing the worms, which are then expelled from the body. It is usually taken as a single dose with food.
- Generic Name: Albendazole + Levamisole
- Manufacturer: Lifecom Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 bemisol 400mg/150mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एल्बेंडाजोल और लेवामिसोल का संयोजन है, जिसका उपयोग आंतों के कीड़ों के संक्रमण के इलाज के लिए किया जाता है। यह दवा कीड़ों को लकवा मारकर मार देती है, जिससे वे मल के माध्यम से शरीर से बाहर निकल जाते हैं। यह आमतौर पर गोल कृमि, हुकवर्म, पिनवर्म और अन्य आंतों के परजीवियों के इलाज के लिए निर्धारित की जाती है। इस दवा को भोजन के साथ लेना चाहिए और डॉक्टर के निर्देशानुसार ही सेवन करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, सिरदर्द, चक्कर आना और थकान शामिल हो सकते हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभावों में एलर्जी, रक्त विकार, यकृत की समस्या और त्वचा पर गंभीर प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको कोई भी गंभीर लक्षण दिखाई दे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। इस दवा को लेते समय शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों को यह दवा डॉक्टर की सलाह के बिना न दें। दवा को बच्चों की पहुंच से दूर रखें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें।
💊 bemisol 400mg/150mg tablet Uses & Benefits
[{"condition":"Intestinal roundworm infection (Ascariasis)","description":"This medicine is used to treat infections caused by Ascaris lumbricoides, a common roundworm that can cause abdominal pain, malnutrition, and intestinal blockage.","evidence":"Well-established"},{"condition":"Hookworm infection (Ancylostomiasis)","description":"This medicine is effective against hookworms such as Ancylostoma duodenale and Necator americanus, which can cause anemia and nutritional deficiencies.","evidence":"Well-established"},{"condition":"Pinworm infection (Enterobiasis)","description":"This medicine may be used to treat pinworm infections, although other agents are often preferred.","evidence":"Limited"},{"condition":"Strongyloidiasis","description":"This medicine may be used in some cases of Strongyloides stercoralis infection, but efficacy may vary.","evidence":"Limited"},{"condition":"Mixed intestinal worm infections","description":"The combination of albendazole and levamisole is sometimes used to treat multiple types of intestinal worms at the same time.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Cutaneous larva migrans","description":"Albendazole, a component of this medicine, is sometimes used off-label to treat skin infections caused by hookworm larvae.","evidence":"Limited"},{"condition":"Giardiasis","description":"Albendazole has been used off-label for Giardia intestinalis infections, but it is not the first-line treatment.","evidence":"Limited"}]
Primary treatment for: Intestinal worm infections
Also treats: Ascariasis, Hookworm infection, Pinworm infection, Strongyloidiasis
📋 Drug Information
| Generic Name(s) | Albendazole + Levamisole |
| Brand Name | Brutal Tablet |
| Manufacturer | Lifecom Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Anthelmintic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends albendazole or mebendazole for preventive chemotherapy of soil-transmitted helminthiases. The combination of albendazole and levamisole is not specifically recommended by WHO for mass deworming, but may be used in certain clinical settings. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) has not issued specific guidelines for the combination of albendazole and levamisole. However, albendazole is commonly used in India for deworming as per national guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two anthelmintic agents with complementary mechanisms. Albendazole binds to beta-tubulin in parasitic worms, inhibiting microtubule polymerization, which disrupts glucose uptake and energy production, leading to worm paralysis and death. Levamisole acts as a nicotinic acetylcholine receptor agonist, causing persistent depolarization of the worm's muscle cells, resulting in spastic paralysis. The paralyzed worms are then expelled from the gastrointestinal tract by normal peristalsis. This dual mechanism enhances the overall anthelmintic effect against susceptible parasites.
Mechanism Steps
💡 How to Take bemisol 400mg/150mg tablet
Strength: Tablet: Albendazole 400 mg + Levamisole 150 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet (Albendazole 400 mg + Levamisole 150 mg) taken orally with food. For most intestinal worm infections, a single dose is sufficient. However, the exact dose and duration depend on the specific infection being treated, the patient's age, weight, and liver function. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. Follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. The dose is typically based on the child's weight and the specific infection. Do not give this medicine to children under 2 years of age unless prescribed by a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution. Dose adjustment may be necessary based on liver and kidney function. Consult your doctor. |
| Renal Impairment | No specific dose adjustment is established for patients with renal impairment. Use with caution. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Monitor liver function. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of bemisol 400mg/150mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Phenytoin | Major | |
| Carbamazepine | Major | |
| Cimetidine | Moderate | |
| Dexamethasone | Moderate | |
| Ritonavir | Moderate | |
| Praziquantel | Moderate | |
| Theophylline | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- Phenytoin
- Carbamazepine
- Cimetidine
- Dexamethasone
⚡ Moderate Interactions
- Ritonavir
- Praziquantel
- Theophylline
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol may increase the risk of liver toxicity and worsen side effects such as dizziness, drowsiness, and nausea. It is best to abstain from alcohol until you have completed the course and consulted your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to albendazole, levamisole, or any component of the formulation.","Pregnancy, especially during the first trimester, unless clearly needed.","Breastfeeding without medical advice.","Children under 2 years of age (unless specifically prescribed by a pediatrician).","Severe liver disease.","Blood disorders such as agranulocytosis or severe thrombocytopenia."]
⚠️ Warnings & Precautions
["Use with caution in patients with liver disease. Monitor liver function.","Use with caution in patients with kidney disease. Dose adjustment may be needed.","Use with caution in patients with blood disorders. Monitor blood counts.","Avoid alcohol during treatment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use in pregnancy unless clearly needed. Consult your doctor.","Not recommended for children under 2 years without medical advice.","Complete the full course as prescribed to ensure eradication of the infection.","Practice good hygiene to prevent reinfection.","Inform your doctor if you are taking any other medications, especially warfarin, phenytoin, or carbamazepine."]
🤱 Lactation Safety
It is not known whether albendazole and levamisole are excreted in human breast milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a breastfeeding woman. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhea, abdominal pain, dizziness, and potentially liver toxicity or blood disorders. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor liver function and blood counts.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. This medicine is usually taken with food to reduce stomach upset. Avoid drinking alcohol while taking this medicine, as it may increase the risk of liver problems and worsen side effects such as dizziness. Inform your doctor if you have a history of liver disease, kidney disease, or blood disorders before taking this medicine. Do not use this medicine if you are pregnant or planning to become pregnant without consulting your doctor first. If you are breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of the reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not share this medicine with others, even if they have similar symptoms. Complete the full course as prescribed, even if you start feeling better after the first dose. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. If you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek emergency medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, especially dizziness and liver toxicity. Use with caution and monitor liver and kidney function. Dose adjustment may be necessary.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is advisable to avoid this medicine during pregnancy, especially in the first trimester. Use effective contraception while taking this medicine if you are of childbearing age.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery. Your doctor will advise you on whether to continue or temporarily stop the medicine.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific precautions, but it is important for your healthcare provider to know your medication history.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue. Avoid strenuous exercise or activities requiring alertness until you know how the medicine affects you. Light exercise is generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, fatigue, or headache, which can affect your ability to drive or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. Most people can continue their normal daily activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, stop the medicine and seek medical attention immediately. Your doctor will advise you on whether to continue or switch to an alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically prescribed for a chronic infection. Prolonged use may increase the risk of liver toxicity and blood disorders. Regular monitoring of liver function and blood counts may be required if long-term therapy is necessary. Always consult your doctor before taking this medicine for an extended period.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another anthelmintic that may be used as an alternative for certain worm infections.
Evidence: Well-establishedAn alternative for pinworm and roundworm infections.
Evidence: Well-establishedPrevents reinfection and complements medical treatment.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue taking the medicine as prescribed; no specific time zone adjustment is needed for a single-dose regimen. Check customs regulations for carrying prescription medicines. Keep it in your carry-on luggage to avoid loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but it may take 1-3 days for the worms to be expelled. Follow-up stool tests are usually done after 1-2 weeks to confirm cure.
A: It is best to take this medicine with food to reduce stomach upset and improve absorption. Taking it on an empty stomach may increase the risk of nausea.
A: This medicine should only be given to children under medical supervision. The dose is determined by a pediatrician based on the child's weight and the type of infection.
A: This medicine should be avoided during pregnancy, especially in the first trimester, unless clearly needed. Consult your doctor if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for bemisol 400mg/150mg tablet
View AllAlternative brands with exact same active ingredient:
-
midazole 400mg/150mg tabletChemida Labs Pvt Ltd ₹11.20 29.7% CHEAPER
-
eradix 400mg/150mg tabletSresan Pharmaceuticals ₹12.00 24.7% CHEAPER
-
megmabend leo 400mg/150mg tabletRidhima Biocare ₹14.06 11.7% CHEAPER
-
wormis l 400 mg/150 mg tabletAaron Pharmaceuticals Pvt Ltd ₹18.71 17.5% COSTLIER
-
leben 400 mg/150 mg tabletMDC Pharmaceuticals Pvt Ltd ₹18.75 17.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: This medicine can cure all types of worm infections.
Fact: This medicine is effective against specific intestinal worms. It may not be effective for all parasitic infections. - Myth: You can stop taking this medicine once symptoms improve.
Fact: You should complete the full course as prescribed to ensure the infection is fully cleared.
🔄 Alternative Options
Generic Alternatives
- Albendazole 400 mg + Levamisole 150 mg tablet (generic)
Brand Alternatives
- Brutal Tablet