coligo 40mg drop - Dicyclomine (40mg) medicine

Coligo 40mg Drop: Complete Medicine Guide

No reviews yet
🏭 Biostrass Health Sciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for IBS and functional bowel disorders.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is coligo 40mg drop used for?

This medicine is an antispasmodic used to treat irritable bowel syndrome and other functional bowel disorders. It works by relaxing the muscles in the stomach and intestines, relieving cramps and pain.

  • Generic Name: Dicyclomine
  • Manufacturer: Biostrass Health Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 coligo 40mg drop के बारे में (Hindi Summary)

उपयोग: यह दवा पेट और आंतों की ऐंठन और दर्द को कम करने के लिए इस्तेमाल की जाती है। यह चिड़चिड़ा आंत्र सिंड्रोम (IBS) और अन्य कार्यात्मक आंत्र विकारों के इलाज में मदद करती है। यह मांसपेशियों को आराम देकर काम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मुंह सूखना, धुंधली दृष्टि, चक्कर आना, नींद आना, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन तेज़ दिल की धड़कन, पेशाब करने में कठिनाई, या गंभीर एलर्जी हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। जब तक आपको इस दवा का असर पता न चल जाए, वाहन न चलाएं। शराब न पिएं। यदि आपको ग्लूकोमा, पेशाब रोकने की समस्या, या लीवर/किडनी की बीमारी है तो डॉक्टर को बताएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 coligo 40mg drop Uses & Benefits

[{"condition":"Irritable bowel syndrome (IBS)","description":"Relieves abdominal cramps and pain associated with IBS by relaxing intestinal smooth muscle.","evidence":"Well-established"},{"condition":"Functional bowel disorders","description":"Used to treat spasms and discomfort in the gastrointestinal tract.","evidence":"Well-established"},{"condition":"Infantile colic","description":"Sometimes prescribed for colic in infants, but only under strict medical supervision.","evidence":"Limited"}]

Off-label uses: [{"condition":"Biliary dyskinesia","description":"May be used off-label to relieve spasms of the biliary tract.","evidence":"Limited"},{"condition":"Urinary bladder spasms","description":"Occasionally used to relax bladder muscles in certain conditions.","evidence":"Limited"}]

Primary treatment for: Irritable bowel syndrome

Also treats: Functional bowel disorders, Infantile colic

📋 Drug Information

Generic Name(s)Dicyclomine
Brand NameBencolic 20mg Tablet
ManufacturerBiostrass Health Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAnticholinergic- antispasmodic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine.
4
Stay hydrated and increase fiber intake to prevent constipation.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual symptoms like rapid heartbeat or difficulty urinating immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDicyclomine is well absorbed from the gastrointestinal tract after oral administration.
DistributionIt is distributed widely in the body, including the gastrointestinal tract, liver, and kidneys.
Protein BindingApproximately 80% bound to plasma proteins.
MetabolismMetabolized in the liver via oxidation and conjugation.
Half-LifeApproximately 1.5 to 2 hours.
ExcretionPrimarily excreted in urine as metabolites and unchanged drug.
BioavailabilityApproximately 50-60% due to first-pass metabolism.
Onset of ActionWithin 30 to 60 minutes after oral administration.
Peak Plasma Time1 to 2 hours.
Duration of Action4 to 6 hours.

How It Works

Dicyclomine works by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions. By antagonizing muscarinic receptors on smooth muscle cells, it reduces muscle spasms and pain in the gastrointestinal tract.

Mechanism Steps

1
Binding to muscarinic receptors: Dicyclomine binds to muscarinic acetylcholine receptors on the surface of smooth muscle cells in the gut.
2
Blocking acetylcholine action: By occupying these receptors, it prevents acetylcholine from binding and triggering muscle contractions.
3
Relaxation of smooth muscle: The blockade leads to relaxation of the smooth muscle, relieving spasms and reducing pain.
4
Reduced motility and secretion: This results in decreased gastrointestinal motility and reduced secretion of acid and digestive enzymes.

💡 How to Take coligo 40mg drop

Strength: Oral drops, 40mg per ml.

1Shake the bottle well before use.
2Use the dropper provided to measure the prescribed dose.
3Place the drops directly into the mouth or mix with a small amount of water or juice.
4Take with food or milk to reduce stomach upset.
5Follow your doctor's instructions carefully.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 to 20 mg three to four times daily, depending on the severity of symptoms. The dose may be adjusted by your doctor based on your response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 160 mg for adults.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of coligo 40mg drop

✅ Common Side Effects

Dry mouth (Common (10-30%))
Sip water, chew sugar-free gum, or use saliva substitutes. Consult doctor if severe.
Blurred vision (Common (5-15%))
Avoid driving until vision clears. Consult doctor if persistent.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Drowsiness (Common (5-10%))
Avoid driving or operating machinery. Consult doctor if excessive.
Nausea (Common (5-10%))
Take with food or milk. Consult doctor if persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if severe.

🚨 Serious Side Effects

Rapid heartbeat (tachycardia) (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations or chest pain.
Difficulty urinating (Rare (<0.1%))
Consult doctor immediately if you cannot urinate.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, or difficulty breathing.
Confusion or hallucinations (Rare (<0.1%))
Discontinue and seek medical help immediately.
Heat stroke (Rare (<0.1%))
Avoid hot environments. Seek medical help if you develop high fever, hot dry skin, or confusion.

⚠️ Rare Side Effects

Psychosis
Seek immediate medical attention.
Seizures
Call emergency services.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Atropine Major
MAO inhibitors Major
Potassium chloride Major
Antihistamines Moderate
Tricyclic antidepressants Moderate
Opioids Moderate
Antacids Minor
Corticosteroids Minor

🚨 Major Interactions

  • Anticholinergic drugs (e.g., atropine, benztropine)
  • MAO inhibitors
  • Potassium chloride (solid oral dosage forms)

⚡ Moderate Interactions

  • Antihistamines
  • Tricyclic antidepressants
  • Opioid analgesics

🍷 Alcohol Interaction

Alcohol can increase drowsiness and dizziness caused by this medicine. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Glaucoma","Urinary retention","Myasthenia gravis","Severe ulcerative colitis","Infants less than 6 months of age","Hypersensitivity to dicyclomine"]

⚠️ Warnings & Precautions

["Avoid in patients with glaucoma.","Use with caution in elderly due to increased risk of confusion.","Avoid in patients with urinary retention.","May impair ability to drive or operate machinery.","Avoid alcohol.","Use with caution in liver or kidney disease.","Do not use for prolonged periods without medical supervision."]

🤱 Lactation Safety

Dicyclomine may pass into breast milk and could cause side effects in the infant. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe anticholinergic symptoms such as delirium, tachycardia, hyperthermia, and urinary retention. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Avoid alcohol while taking this medicine as it can increase drowsiness. Inform your doctor if you have glaucoma, urinary retention, or liver/kidney disease. Do not use this medicine for prolonged periods without medical supervision. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to anticholinergic effects. Use with caution and monitor for confusion, urinary retention, and falls.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy. This medicine is Category B; use only if clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine. It may affect bowel motility post-surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and affect oral health.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce abdominal pressure.
🥗
Regular low-impact exercise like walking or swimming.
😴
Practice stress-reduction techniques like yoga or meditation.
💧
Include fiber-rich foods in your diet.
🧘
Get adequate sleep.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after taking this medicine if you experience dizziness or drowsiness.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or blurred vision, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. It may cause tolerance and increased side effects. Regular monitoring of heart rate, urinary function, and bowel habits is advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Low-FODMAP diet can help manage IBS symptoms.

Evidence: Well-established
Stress management

Yoga, meditation, and counseling can reduce stress-related IBS flares.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with IBS
She was prescribed this medicine for abdominal cramps. She noticed relief within 30 minutes of taking the drops. She experienced dry mouth initially, which subsided after a week. She was advised to take it with food.
💡 Lesson: Taking this medicine with food reduces stomach upset and improves tolerability.
👤 A 50-year-old man with functional bowel disorder
He started this medicine as prescribed. His abdominal pain decreased significantly. He was cautioned about drowsiness and advised not to drive immediately after taking the dose.
💡 Lesson: Avoid driving until you know how this medicine affects you.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after oral administration.

Q: Can I take this medicine with other medications?

A: Inform your doctor about all medications you are taking, as this medicine can interact with several drugs.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure IBS permanently.
    Fact: This medicine only provides symptomatic relief and does not cure the underlying condition.
  • Myth: This medicine is safe for everyone.
    Fact: It is not safe for people with glaucoma, urinary retention, or myasthenia gravis.
  • Myth: You can stop this medicine abruptly without consulting a doctor.
    Fact: Always consult your doctor before stopping this medicine.

🔄 Alternative Options

Generic Alternatives

  • Dicyclomine 40mg oral drops

Brand Alternatives

  • Coligo 40mg drop

📊 Comparison with Similar Medicines

[{"medicine":"Dicyclomine","class":"Anticholinergic","main_use":"IBS, functional bowel disorders","common_side_effects":"Dry mouth, blurred vision, dizziness"},{"medicine":"Hyoscyamine","class":"Anticholinergic","main_use":"IBS, gastrointestinal spasms","common_side_effects":"Dry mouth, blurred vision, constipation"},{"medicine":"Mebeverine","class":"Antispasmodic","main_use":"IBS","common_side_effects":"Nausea, headache, dizziness"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory