coldwar suspension - Chlorpheniramine Maleate (1mg) + Phenylephrine (2.5mg) medicine

Coldwar Suspension: Complete Medicine Guide

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🏭 Corona Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe headache with blurred vision or confusion
  • Chest pain, palpitations, or irregular heartbeat
  • Difficulty breathing or swelling of face, lips, or throat
  • Inability to urinate or severe abdominal pain
  • Yellowing of skin or eyes, dark urine
  • Severe drowsiness or fainting
  • High fever with rash or persistent symptoms beyond 7 days

If experiencing severe symptoms, call emergency services immediately.

What is coldwar suspension used for?

This medicine is a combination of chlorpheniramine (an antihistamine) and phenylephrine (a decongestant) used to relieve symptoms of cold and allergies such as runny nose, sneezing, and nasal congestion. It works by blocking histamine and constricting nasal blood vessels. It may cause drowsiness, so avoid driving. Do not use for more than 7 days without consulting a doctor.

  • Generic Name: Chlorpheniramine Maleate + Phenylephrine
  • Manufacturer: Corona Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 coldwar suspension के बारे में (Hindi Summary)

उपयोग: यह दवा सर्दी और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, नाक बंद होना और आंखों में पानी आना को कम करने के लिए उपयोग की जाती है। यह क्लोरफेनिरामाइन और फेनिलएफ्रिन का संयोजन है। क्लोरफेनिरामाइन एक एंटीहिस्टामिन है जो एलर्जी के लक्षणों को कम करता है, और फेनिलएफ्रिन एक डिकंजेस्टेंट है जो नाक की भीड़ को कम करता है। यह दवा नींद ला सकती है, इसलिए वाहन चलाने से बचें। इसका उपयोग 7 दिनों से अधिक न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, मतली और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में तेज धड़कन, रक्तचाप में वृद्धि, पेशाब में रुकावट और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि कोई दुष्प्रभाव बना रहता है या बिगड़ जाता है, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन चलाने या भारी मशीनरी चलाने से बचें। इस दवा के साथ शराब और अन्य केंद्रीय तंत्रिका तंत्र अवसादकों से बचें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड समस्या, ग्लूकोमा या पेशाब करने में कठिनाई है, तो अपने डॉक्टर को बताएं। बिना डॉक्टर की सलाह के इस दवा का उपयोग 7 दिनों से अधिक न करें। बच्चों की पहुंच से दूर रखें। यदि आप गर्भवती या स्तनपान करा रही हैं, तो उपयोग से पहले अपने डॉक्टर से परामर्श करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 coldwar suspension Uses & Benefits

[{"condition":"Common cold","description":"Provides temporary relief of nasal congestion, runny nose, sneezing, and watery eyes associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Relieves symptoms of seasonal or perennial allergic rhinitis, including sneezing, rhinorrhea, and nasal itching.","evidence":"Well-established"},{"condition":"Upper respiratory tract allergy","description":"Helps reduce allergic symptoms affecting the nose and throat.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Common cold and allergic rhinitis

Also treats: Sinusitis, Otitis media, Pharyngitis

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate + Phenylephrine
Brand NameAscoril Flu Syrup
ManufacturerCorona Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Decongestant
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid driving or operating machinery until you know how this medicine affects you.
3
Do not take this medicine for more than 7 days without consulting your doctor.
4
Avoid alcohol and other CNS depressants while taking this medicine.
5
Inform your doctor if you have high blood pressure, heart disease, or glaucoma before taking this medicine.
6
Keep out of reach of children and store in a cool, dry place.
7
If symptoms persist or worsen, consult your doctor promptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing
This medicine helps relieve sneezing due to allergies.
Likely Use
✅
Nasal congestion
This medicine contains a decongestant to reduce nasal swelling.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Body ache
This medicine is not indicated for body aches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine maleate is well absorbed from the gastrointestinal tract after oral administration. Phenylephrine is also absorbed orally but undergoes extensive first-pass metabolism, resulting in reduced systemic bioavailability.
DistributionChlorpheniramine is widely distributed throughout body tissues and crosses the blood-brain barrier. Phenylephrine distribution is not well characterized but is expected to distribute to vascular tissues.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Protein binding of phenylephrine is not established from the available information.
MetabolismChlorpheniramine is metabolized in the liver, primarily via N-demethylation and oxidative deamination. Phenylephrine is metabolized in the liver and intestine by monoamine oxidase and sulfotransferases.
Half-LifeThe elimination half-life of chlorpheniramine is approximately 12 to 43 hours. The elimination half-life of phenylephrine is approximately 2 to 3 hours.
ExcretionChlorpheniramine and its metabolites are excreted primarily in the urine. Phenylephrine metabolites are excreted in the urine, with a small amount excreted unchanged.
BioavailabilityChlorpheniramine oral bioavailability is approximately 25% to 50%. Phenylephrine oral bioavailability is low and variable, approximately 38% due to first-pass metabolism.
Onset of ActionThe onset of action for chlorpheniramine is about 30 to 60 minutes after oral administration. Phenylephrine nasal decongestant effect begins within 15 to 30 minutes.
Peak Plasma TimePeak plasma concentration of chlorpheniramine is reached in about 2 to 6 hours. Peak plasma concentration of phenylephrine is reached in about 1 to 2 hours.
Duration of ActionThe duration of action for chlorpheniramine is approximately 4 to 6 hours. The decongestant effect of phenylephrine lasts about 4 to 6 hours.

How It Works

This medicine combines an antihistamine and a decongestant. Chlorpheniramine maleate competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract, thereby reducing allergic symptoms. Phenylephrine is an alpha-1 adrenergic receptor agonist that causes vasoconstriction of nasal mucosal blood vessels, leading to reduced swelling and congestion.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine maleate binds to H1 receptors, preventing histamine from triggering allergic responses such as sneezing, itching, and vasodilation.
2
Alpha-1 adrenergic receptor stimulation: Phenylephrine stimulates alpha-1 receptors on nasal blood vessels, causing them to constrict and reducing blood flow and swelling in the nasal mucosa.
3
Reduction of nasal congestion: The vasoconstrictive action of phenylephrine decreases nasal airway resistance, making breathing easier.
4
Anticholinergic effects: Chlorpheniramine also exhibits anticholinergic properties, which contribute to drying of respiratory secretions, further alleviating runny nose.

💡 How to Take coldwar suspension

Strength: Each 5 mL of suspension contains Chlorpheniramine Maleate 1 mg and Phenylephrine 2.5 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take the medicine orally, with or without food.
4Follow the dosage instructions provided by your doctor.
5Do not exceed the recommended dose or duration of use.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 mL (2 teaspoons) orally every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. However, dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. This medicine is not recommended for children under 2 years of age.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor for individualized dosing.
Maximum Daily DoseFor adults: Maximum 6 doses (60 mL) in 24 hours. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases drowsiness and CNS depression.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of coldwar suspension

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. Usually resolves with continued use.
Dry mouth (Common (5-15%))
Sip water or chew sugarless gum. Consult doctor if persistent.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Hypertensive crisis (Rare (<0.1%))
Seek immediate medical attention if you experience severe headache, blurred vision, or chest pain.
Urinary retention (Rare (<0.1%))
Consult a doctor if you are unable to urinate or have difficulty passing urine.
Severe allergic reaction (anaphylaxis) (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, tongue, or throat, or difficulty breathing.
Cardiac arrhythmias (Rare (<0.1%))
Seek medical attention if you notice palpitations, irregular heartbeat, or fainting.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising, bleeding, or signs of infection to your doctor.
Hepatotoxicity
Seek medical attention if you develop yellowing of skin or eyes, dark urine, or abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
Digoxin Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Digoxin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair motor skills. Combined use may also increase the risk of central nervous system depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, phenylephrine, or any component of the formulation","Severe hypertension or severe coronary artery disease","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Concurrent use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs","Children under 2 years of age"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in patients with hypertension, cardiovascular disease, diabetes, thyroid disorders, or glaucoma.","Do not exceed recommended dose or duration of use without medical advice.","Elderly patients may be more sensitive to side effects.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever."]

🤱 Lactation Safety

Chlorpheniramine and phenylephrine may pass into breast milk. Consult your doctor before using this medicine while breastfeeding. Drowsiness in the infant is a potential concern.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, confusion, tachycardia, hypertension, and in severe cases, seizures, coma, or cardiac arrest. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid alcohol and other central nervous system depressants while taking this medicine. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or difficulty urinating. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more likely to experience side effects such as drowsiness, dizziness, dry mouth, and urinary retention. They may also be more sensitive to the effects of phenylephrine on blood pressure. Use with caution and consider lower doses. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy has not been fully established. Your doctor will weigh the benefits against potential risks.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your doctor. It may interact with other medications used during or after surgery, such as anesthetics or pain relievers. Inform your surgeon and anesthesiologist about all medications you are taking.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. The anticholinergic effects may cause dry mouth, which can affect dental health. Also, the sedative effects may interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus and relieve congestion.
🥗
Use a humidifier to add moisture to the air and ease breathing.
😴
Get plenty of rest to support your immune system.
💧
Avoid exposure to allergens such as dust, pollen, and pet dander.
🧘
Practice good hand hygiene to prevent spreading infections.
🌞
Use saline nasal sprays to help clear nasal passages.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can affect your coordination. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Light activities like walking may be fine if you feel up to it.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or soup to soothe your throat and loosen mucus.
Include foods rich in vitamin C such as oranges, strawberries, and bell peppers to support immune function.
Avoid dairy products if they seem to thicken mucus, though this varies by individual.
Stay hydrated with water and clear broths.
Avoid alcohol and caffeine, which can worsen dehydration and interact with the medicine.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may impair your ability to drive or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. If your work requires alertness, discuss with your doctor about alternative options. The sedative effect may also affect concentration and productivity.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as severe drowsiness, palpitations, or difficulty urinating. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of decongestants like phenylephrine can lead to rebound congestion. Antihistamines like chlorpheniramine may cause tolerance to sedative effects. Regular monitoring of blood pressure and symptoms is advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Using a saline solution to rinse nasal passages can help relieve congestion without medication.

Evidence: Well-established
Steam inhalation

Inhaling steam from a bowl of hot water can help loosen mucus and ease breathing.

Evidence: Traditional
Antihistamine nasal sprays

Prescription nasal sprays like azelastine can provide allergy relief with fewer systemic side effects.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for a vaccination, inform your healthcare provider about all medications you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, continue your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medications across borders. Keep a list of your medications with you in case of emergency.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergic rhinitis
She was prescribed this medicine for her runny nose and sneezing. She took it as directed and noticed relief within 30 minutes. She experienced mild drowsiness, so she avoided driving after taking it. She was advised not to use it for more than a week.
💡 Lesson: This medicine provides quick relief from allergy symptoms but can cause drowsiness; avoid driving and limit duration of use.
👤 A 50-year-old man with common cold and nasal congestion
He used this medicine for his cold symptoms. His nasal congestion improved significantly, but he experienced dry mouth. He was advised to stay hydrated and use sugarless gum. He stopped the medicine after 5 days as symptoms resolved.
💡 Lesson: Dry mouth is a common side effect that can be managed with hydration and sugarless gum. Do not exceed the recommended duration.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after oral administration.

Q: How long does the effect last?

A: The effects typically last for about 4 to 6 hours, so it may need to be taken every 4 to 6 hours as needed.

Q: Can I take this medicine with food?

A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.

Q: Is it safe to take this medicine during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. The risk-benefit must be assessed by your healthcare provider.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for children?
  • Can I take it with other cold medicines?

🔄 Substitutes for coldwar suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: This medicine should not be used for more than 7 days without medical advice due to risk of side effects.
  • Myth: This medicine is safe for children under 2 years.
    Fact: This medicine is not recommended for children under 2 years due to risk of serious side effects.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine + Phenylephrine suspension

Brand Alternatives

  • Coldwar Suspension

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Chlorpheniramine + Phenylephrine","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine + Phenylephrine","active_ingredients":"Cetirizine + Phenylephrine","sedation":"Low","duration":"24 hours"},{"medicine":"Loratadine + Pseudoephedrine","active_ingredients":"Loratadine + Pseudoephedrine","sedation":"Low","duration":"12-24 hours"}]

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